Microgravity-induced transcriptome adaptation in mouse paraspinal longissimus dorsi muscle highlights insulin resistance-linked genes

Frontiers in Physiology

Volumn 8, Issue MAY, 2017, Pages

  Gambara, Guido ^a   Salanova, Michele ^a   Ciciliot, Stefano ^b,c   Furlan, Sandra ^d   Gutsmann, Martina ^a   Schiffl, Gudrun ^a   Ungethuem, Ute ^a   Volpe, Pompeo ^c   Gunga, Hanns Christian ^a   Blottner, Dieter ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b VENETIAN INSTITUTE OF MOLECULAR MEDICINE   (Italy)

^c UNIVERSITY OF PADOVA   (Italy)

^d CNR   (Italy)

Author keywords

BION M1; Disuse; Gene expression; Insulin resistance; Microarray; Microgravity; Skeletal muscle; Spaceflight

Indexed keywords

ATROGIN 1; MUSCLE RING FINGER 1 PROTEIN; MYOSIN HEAVY CHAIN; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PROTEIN KINASE C DELTA; TRANSCRIPTION FACTOR MAFB; TRANSCRIPTOME;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENETIC ANALYSIS; INSULIN RESISTANCE; INSULIN SENSITIVITY; LCN2 GENE; LONGISSIMUS MUSCLE; MAFB GENE; MAFBX GENE; MALE; MICROGRAVITY; MORPHOLOGY; MOUSE; MURF 1 GENE; NONHUMAN; PARASPINAL MUSCLE; PIK3R1 GENE; PRKCD GENE; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SESN1 GENE; TRANSCRIPTION REGULATION; UPREGULATION;

EID: 85019712332     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2017.00279     Document Type: Article

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