Structural modification of lipopolysaccharide conferred by mcr-1 in gram-negative ESKAPE pathogens

Antimicrobial Agents and Chemotherapy

Volumn 61, Issue 6, 2017, Pages

  Liu, Yi Yun ^a,b   Chandler, Courtney E ^c   Leung, Lisa M ^c   McElheny, Christi L ^a   Mettus, Roberta T ^a   Shanks, Robert M Q ^a   Liu, Jian Hua ^b   Goodlett, David R ^d   Ernst, Robert K ^c   Doi, Yohei ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b SOUTH CHINA AGRICULTURAL UNIVERSITY   (China)

^c UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

Lipid A; Phosphoethanolamine; Plasmid; Plasmidmediated resistance; Polymyxin resistance; Polymyxins

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; COLISTIN; ETHANOLAMINE PHOSPHOTRANSFERASE; MCR 1 PROTEIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; LIPOPOLYSACCHARIDE; POLYMYXIN;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ARTICLE; CONTROLLED STUDY; ENTEROBACTER; ENTEROCOCCUS FAECIUM; ENZYME MODIFICATION; HYDROXYLATION; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RECOMBINANT PLASMID; STAPHYLOCOCCUS AUREUS; DRUG EFFECTS; ESCHERICHIA COLI; GENETICS; METABOLISM; MICROBIAL SENSITIVITY TEST; PLASMID;

ACINETOBACTER BAUMANNII; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; COLISTIN; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; LIPOPOLYSACCHARIDES; MICROBIAL SENSITIVITY TESTS; PLASMIDS; POLYMYXINS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

EID: 85019671091     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00580-17     Document Type: Article

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