Plasmid-mediated mcr-1 gene in colistin-resistant clinical isolates of Klebsiella pneumoniae in France and Laos

Antimicrobial Agents and Chemotherapy

Volumn 60, Issue 11, 2016, Pages 6994-6995

  Rolain, Jean Marc ^a   Kempf, Marie ^b   Leangapichart, Thongpan ^a   Chabou, Selma ^a   Olaitan, Abiola Olumuyiwa ^a   Le Page, Stéphanie ^a   Morand, Serge ^c,d   Raoult, Didier ^a  

^a AIX MARSEILLE UNIVERSITÉ   (France)

^b ANGERS UNIVERSITY HOSPITAL   (France)

^c INSTITUT DES SCIENCES DE L EVOLUTION   (France)

^d CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AZTREONAM; CEFEPIME; CEFOTAXIME; CEFTRIAXONE; CIPROFLOXACIN; COLISTIN; COTRIMOXAZOLE; DOXYCYCLINE; ERTAPENEM; FOSFOMYCIN; GENTAMICIN; IMIPENEM; MEROPENEM; MINOCYCLINE; NALIDIXIC ACID; NITROFURANTOIN; PIPERACILLIN PLUS TAZOBACTAM; TICARCILLIN; TIGECYCLINE; TOBRAMYCIN; ANTIINFECTIVE AGENT;

AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; BACTERIAL GENE; BACTERIUM ISOLATE; CHILD; FECES; FRANCE; GENE SEQUENCE; HUMAN; KLEBSIELLA PNEUMONIAE; LAOS; LETTER; MCR 1 GENE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PLASMID; PRESCHOOL CHILD; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; VERY ELDERLY; DRUG EFFECT; GENETICS; ISOLATION AND PURIFICATION;

ANTI-BACTERIAL AGENTS; COLISTIN; DRUG RESISTANCE, BACTERIAL; FRANCE; KLEBSIELLA PNEUMONIAE; LAOS; PLASMIDS;

EID: 84994494777     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00960-16     Document Type: Letter

References (7)

1. Liu Y-Y, Wang Y, Walsh TR, Yi L-X, Zhang R, Spencer J, Doi Y, Tian G, Dong B, Huang X, Yu L-F, Gu D, Ren H, Chen X, Lv L, He D, Zhou H, Liang Z, Liu J-H, Shen J. 2016. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study. Lancet Infect Dis 16:161-168. http://dx.doi.org/10.1016/S1473-3099(15)00424-7.
2. Olaitan AO, Chabou S, Okdah L, Morand S, Rolain J-M. 2016. Dissemination of the mcr-1 colistin resistance gene. Lancet Infect Dis 16:147. http://dx.doi.org/10.1016/S1473-3099(15)00540-X.
3. Olaitan AO, Morand S, Rolain J-M. 2016. Emergence of colistin-resistant bacteria in humans without colistin usage: a new worry and cause for vigilance. Int J Antimicrob Agents 47:1-3. http://dx.doi.org/10.1016/j.ijantimicag.2015.11.009.
4. Rolain J-M, Olaitan AO. 2016. Plasmid-mediated colistin resistance: the final blow to colistin? Int J Antimicrob Agents 47:4-5. http://dx.doi.org/10.1016/j.ijantimicag.2015.11.010.
5. Chabou S, Leangapichart T, Okdah L, Le Page S, Hadjadj L, Rolain J-M. 2016. Real-time quantitative PCR assay with Taqman® probe for rapid detection of MCR-1 plasmid-mediated colistin resistance. New Microbes New Infect 13:71-74. http://dx.doi.org/10.1016/j.nmni.2016.06.017.
6. Olaitan AO, Diene SM, Kempf M, Berrazeg M, Bakour S, Gupta SK, Thongmalayvong B, Akkhavong K, Somphavong S, Paboriboune P, Chaisiri K, Komalamisra C, Adelowo OO, Fagade OE, Banjo OA, Oke AJ, Adler A, Assous MV, Morand S, Raoult D, Rolain J-M. 2014. Worldwide emergence of colistin resistance in Klebsiella pneumoniae from healthy humans and patients in Lao PDR, Thailand, Israel, Nigeria and France owing to inactivation of the PhoP/PhoQ regulator mgrB: an epidemiological and molecular study. Int J Antimicrob Agents 44:500-507. http://dx.doi.org/10.1016/j.ijantimicag.2014.07.020.
7. Hasman H, Hammerum AM, Hansen F, Hendriksen RS, Olesen B, Agersø Y, Zankari E, Leekitcharoenphon P, Stegger M, Kaas RS, Cavaco LM, Hansen DS, Aarestrup FM, Skov RL. 2015. Detection of mcr-1 encoding plasmid-mediated colistin-resistant Escherichia coli isolates from human bloodstream infection and imported chicken meat, Denmark 2015. Euro Surveill 20:30085. http://dx.doi.org/10.2807/1560-7917.ES.2015.20.49.30085.