Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation

Journal of Biological Chemistry

Volumn 292, Issue 20, 2017, Pages 8244-8261

  Grishkovskaya, X Irina ^a   Paumann Page, Martina ^b   Tscheliessnig, Rupert ^c   Stampler, Johanna ^b   Hofbauer, X Stefan ^a   Soudi, Monika ^b   Sevcnikar, Benjamin ^b   Oostenbrink, X Chris ^b   Furtmüller, X Paul G ^b   Djinović Carugo, X Kristina ^a,e   Nauseef, X William M ^d   Obinger, Christian ^b  

^a UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^c AUSTRIAN CENTRE OF INDUSTRIAL BIOTECHNOLOGY   (Austria)

^d UNIVERSITY OF IOWA   (United States)

^e UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; PROTEINS; X RAY SCATTERING;

ENZYMATIC ACTIVITIES; GLYCOSYLATION SITES; HEAVY AND LIGHT CHAINS; N-TERMINAL PROPEPTIDE; SOLUTION STRUCTURES; STRUCTURAL MOTIFS; STRUCTURE-FUNCTION RELATIONSHIP; WILD-TYPE PROTEINS;

CRYSTAL STRUCTURE;

CALNEXIN; HEME; MYELOPEROXIDASE; PROMYELOPEROXIDASE; PROTEIN; UNCLASSIFIED DRUG; ENZYME PRECURSOR; PEROXIDASE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; BIOSYNTHESIS; CONTROLLED STUDY; COVALENT BOND; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME STRUCTURE; GLYCOSYLATION; HUMAN; HUMAN CELL; MATURATION; PRIORITY JOURNAL; PROTEIN PROCESSING; WILD TYPE; X RAY CRYSTALLOGRAPHY; AMINO ACID SUBSTITUTION; CHEMISTRY; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; GOLGI COMPLEX; HEK293 CELL LINE; K-562 CELL LINE; METABOLISM; MISSENSE MUTATION; PHYSIOLOGY; PROTEIN DOMAIN;

AMINO ACID SUBSTITUTION; CALNEXIN; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; ENZYME PRECURSORS; GOLGI APPARATUS; HEK293 CELLS; HUMANS; K562 CELLS; MUTATION, MISSENSE; PEROXIDASE; PROTEIN DOMAINS;

EID: 85019647280     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M117.775031     Document Type: Article

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