Resistance to malaria through structural variation of red blood cell invasion receptors

Science

Volumn 356, Issue 6343, 2017, Pages 1140-1152

  Leffler, Ellen M ^a,b   Band, Gavin ^a,b   Busby, George B J ^a   Kivinen, Katja ^b   Le, Quang Si ^a   Clarke, Geraldine M ^a   Bojang, Kalifa A ^c   Conway, David J ^c,d   Jallow, Muminatou ^c,e   Sisay Joof, Fatoumatta ^c   Bougouma, Edith C ^f   Mangano, Valentina D ^g   Modiano, David ^g   Sirima, Sodiomon B ^f   Achidi, Eric ^h   Apinjoh, Tobias O ^h   Marsh, Kevin ^i,j   Ndila, Carolyne M ⁱ   Peshu, Norbert ⁱ   Williams, Thomas N ^i,k   Drakeley, Chris ^d,l   Manjurano, Alphaxard ^d,l,m   Reyburn, Hugh ^d,l   Riley, Eleanor ^d   Kachala, David ⁿ   Molyneux, Malcolm ^n,o   Nyirongo, Vysaul ⁿ   Taylor, Terrie ^p,q   Thornton, Nicole ^r   Tilley, Louise ^r   Grimsley, Shane ^r   Drury, Eleanor ^b   Stalker, Jim ^b   Cornelius, Victoria ^a   Hubbart, Christina ^a   Jeffreys, Anna E ^a   Rowlands, Kate ^a   Rockett, Kirk A ^a,b   Spencer, Chris C A ^a   Kwiatkowski, Dominic P ^a,b   more..

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^e Royal Victoria Teaching Hospital Gambia   (Gambia)

^f Centre National de Recherche et de Formation Sur le Paludisme   (Burkina Faso)

^g SAPIENZA UNIVERSITY OF ROME   (Italy)

^h UNIVERSITY OF BUEA   (Cameroon)

ⁱ KEMRI WELLCOME TRUST RESEARCH PROGRAMME   (Kenya)

^j UNIVERSITY OF OXFORD   (United Kingdom)

^k IMPERIAL COLLEGE LONDON   (United Kingdom)

^l KILIMANJARO CHRISTIAN MEDICAL CENTRE   (Tanzania)

^m NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (Tanzania)

ⁿ UNIVERSITY OF MALAWI   (Malawi)

^o LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^p QUEEN ELIZABETH CENTRAL HOSPITAL   (Malawi)

^q MICHIGAN STATE UNIVERSITY   (United States)

^r NHS BLOOD AND TRANSPLANT   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD GROUP ANTIGEN; DUP4 PROTEIN; GLYCOPHORIN; GYPA PROTEIN; GYPB PROTEIN; MEMBRANE PROTEIN; PROTEIN; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; GLYCOPHORIN DANTU; GYPA PROTEIN, HUMAN; GYPB PROTEIN, HUMAN;

ANTIGEN; ARRAY; CELLS AND CELL COMPONENTS; DISEASE RESISTANCE; GENOME; HEALTH RISK; MALARIA; PARASITIC DISEASE; PUBLIC HEALTH;

ALLELE; ARTICLE; BLOOD GROUP; BLOOD GROUP SYSTEM; CELL INVASION; CHROMOSOME STRUCTURE; CLINICAL ASSESSMENT; CLINICAL EVALUATION; COPY NUMBER VARIATION; DISEASE ASSOCIATION; DISEASE SEVERITY; ERYTHROCYTE; ETHNIC GROUP; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC RESISTANCE; GENETIC VARIABILITY; GENOME-WIDE ASSOCIATION STUDY; HAPLOTYPE; HUMAN; HUMAN GENOME; HYBRID GENE; INDEL MUTATION; INFECTION RISK; MALARIA; PLASMODIUM FALCIPARUM; POPULATION; PRIORITY JOURNAL; RECEPTOR GENE; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; ADULT; AFRICA SOUTH OF THE SAHARA; CHEMISTRY; CHILD; DISEASE RESISTANCE; GENE FREQUENCY; GENETICS; HOST PARASITE INTERACTION; MALARIA FALCIPARUM; METABOLISM; MOLECULAR MODEL; PARASITOLOGY; PROTEIN SECONDARY STRUCTURE;

KENYA; SUB-SAHARAN AFRICA;

PLASMODIUM FALCIPARUM;

ADULT; AFRICA SOUTH OF THE SAHARA; CHILD; DISEASE RESISTANCE; DNA COPY NUMBER VARIATIONS; ERYTHROCYTES; GENE FREQUENCY; GENOME, HUMAN; GLYCOPHORIN; HOST-PARASITE INTERACTIONS; HUMANS; MALARIA, FALCIPARUM; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, CELL SURFACE;

EID: 85019617478     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aam6393     Document Type: Article

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