Polo-like kinase-dependent phosphorylation of the synaptonemal complex protein SYP-4 regulates double-strand break formation through a negative feedback loop

eLife

Volumn 6, Issue , 2017, Pages

  Nadarajan, Saravanapriah ^a   Lambert, Talley J ^a   Altendorfer, Elisabeth ^a   Gao, Jinmin ^a   Blower, Michael D ^a,b   Waters, Jennifer C ^a   Colaiácovo, Monica P ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDES AND PROTEINS; POLO LIKE KINASE; SYNAPTONEMAL COMPLEX PROTEIN SYP 4; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; NUCLEAR PROTEIN; PLK-1 PROTEIN, C ELEGANS; POLO-LIKE KINASE 2, C ELEGANS; PROTEIN SERINE THREONINE KINASE; SYP-4 PROTEIN, C ELEGANS;

APOPTOSIS; ARTICLE; AUTOSOME; CAENORHABDITIS ELEGANS; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA STRAND BREAKAGE; ENZYME REGULATION; FERRIC REDUCING ANTIOXIDANT POWER ASSAY; FLUORESCENCE IN SITU HYBRIDIZATION; GENOTYPE; IMMUNOFLUORESCENCE; IMMUNOLOCALIZATION; NONHUMAN; PACHYTENE; PHOSPHORYLATION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SYNAPTONEMAL COMPLEX; ANIMAL; DOUBLE STRANDED DNA BREAK; METABOLISM; PHYSIOLOGICAL FEEDBACK; PHYSIOLOGY; PROTEIN PROCESSING;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DNA BREAKS, DOUBLE-STRANDED; FEEDBACK, PHYSIOLOGICAL; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES;

EID: 85019593851     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.23437     Document Type: Article

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