Protective effects of tyrosol against LPS-induced acute lung injury via inhibiting NF-κB and AP-1 activation and activating the HO-1/Nrf2 pathways

Biological and Pharmaceutical Bulletin

Volumn 40, Issue 5, 2017, Pages 583-593

  Wang, Wen Chen ^a   Xia, Yan Min ^a   Yang, Bo ^b   Su, Xiang Ni ^c   Chen, Jia Kuan ^a   Li, Wei ^c   Jiang, Tao ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b TIANJIN FIRST CENTRAL HOSPITAL   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Activator protein (AP) 1; Acute lung injury (ALI); Heme oxygenase (HO) 1; Nuclear factor (NF) B; Nuclear factor erythroid 2 related factor 2(Nrf2); Tyrosol(Tyr)

Indexed keywords

CATALASE; CYCLOOXYGENASE 2; DEXAMETHASONE; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MYELOPEROXIDASE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR; TYROSOL; 4-HYDROXYPHENYLETHANOL; LIPOPOLYSACCHARIDE; NFE2L2 PROTEIN, MOUSE; PEROXIDASE; PHENETHYL ALCOHOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; EMBRYO; ENZYME ACTIVITY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPOPOLYSACCHARIDE-INDUCED ACUTE LUNG INJURY; LOW DRUG DOSE; LUNG ALVEOLUS EPITHELIUM CELL; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SURVIVAL RATE; UPREGULATION; ACUTE LUNG INJURY; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ACUTE LUNG INJURY; ANIMALS; CELLS, CULTURED; HEME OXYGENASE-1; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; NF-KAPPA B; PEROXIDASE; PHENYLETHYL ALCOHOL; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 85019246245     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b16-00756     Document Type: Article

References (34)

1. Ware LB, Matthay MA. The acute respiratory distress syndrome. N. Engl. J. Med., 342, 1334-1349 (2000).
2. Stearns-Kurosawa DJ, Osuchowski MF, Valentine C, Kurosawa S, Remick DG. The pathogenesis of sepsis. Annu. Rev. Pathol., 6, 19-48 (2011).
3. Gilmore TD. Introduction to NF-kappaB: players, pathways, perspectives. Oncogene, 25, 6680-6684 (2006).
4. Kim EK, Choi EJ. Pathological roles of MAPK signaling pathways in human diseases. Biochim. Biophys. Acta, 1802, 396-405 (2010).
5. Liu D, Zeng BX, Shang Y. Decreased expression of peroxisome proliferatoractivated receptor gamma in endotoxin-induced acute lung injury. Physiol. Res., 55, 291-299 (2006).
6. Kuo MY, Liao MF, Chen FL, Li YC, Yang ML, Lin RH, Kuan YH. Luteolin attenuates the pulmonary inflammatory response involves abilities of antioxidation and inhibition of MAPK and NFkappaB pathways in mice with endotoxin-induced acute lung injury. Food Chem. Toxicol., 49, 2660-2666 (2011).
7. Nguyen T, Sherratt PJ, Huang HC, Yang CS, Pickett CB. Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome. J. Biol. Chem., 278, 4536-4541 (2003).
8. Gong Q, Yin H, Fang M, Xiang Y, Yuan CL, Zheng GY, Yang H, Xiong P, Chen G, Gong FL, Zheng F. Heme oxygenase-1 upregulation significantly inhibits TNF-α and Hmgb1 releasing and attenuates lipopolysaccharide-induced acute lung injury in mice. Int. Immunopharmacol., 8, 792-798 (2008).
9. Tuck KL, Hayball PJ. Major phenolic compounds in olive oil: 558 metabolism and health effects. J. Nutr. Biochem., 13, 636-644 (2002).
10. Dudley JI, Lekli I, Mukherjee S, Das M, Bertelli AAA, Das DK. Does white wine qualify for French paradox? Comparison of the cardio protective effects of red and white wine sand their constituents: resveratrol, tyrosol, and hydroxytyrosol. J. Agric. Food Chem., 56, 9362-9373 (2008).
11. Zhou X, Wu Y, Wang X, Liu B, Xu H. Salidroside production by hairy roots of rhodiola sachalinensis obtained after transformation with agrobacterium rhizogenes. Biol. Pharm. Bull., 30, 439-442 (2007).
12. Choe KI, Kwon JH, Park KH, Oh MH, Kim MH, Kim HH, Cho SH, Chung EK, Ha SY, Lee MW. The Antioxidant and Anti-inflammatory effects of phenolic compounds isolated from the root of rhodiola sachalinensis A. BOR. Molecules, 17, 11484-11494 (2012).
13. Sun L, Isaak CK, Zhou Y, Petkau JC, O K, Liu Y, Siow YL. Salidroside and Tyrosol from Rhodiola protect H9c2 cell from ischemia/reperfusion-induced apoptosis. Life Sci., 91, 151-158 (2012).
14. Bertelli A, Migliori M, Bertelli AA, Origlia N, Filippi C, Panichi V, Falchi M, Giovannini L. Effect of some white wine phenols in preventing inflammatory cytokine release. Drugs Exp. Clin. Res., 28, 11-15 (2002).
15. Stiuso P, Bagarolo ML, Ilisso CP, Vanacore D, Martino E, Caraglia M, Porcelli M, Cacciapuoti G. Protective effect of tyrosol and S-adenosylmethionine against ethanol-induced oxidative stress of Hepg2 cells involves sirtuin 1, P53 and Erk1/2 signaling. Int. J. Mol. Sci., 17, 622 (2016).
16. Lee TS, Chau LY. Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat. Med., 8, 240-246 (2002).
17. Lee SY, Li MH, Shi LS, Chu H, Ho CW, Chang TC. Rhodiola crenulata extract alleviates hypoxic pulmonary edema in rats. Evid. Based Complement. Alternat. Med., 2013, 718739 (2013).
18. Matute-Bello G, Winn RK, Jonas M, Chi EY, Martin TR, Liles WC. Fas (CD95) induces alveolar epithelial cell apoptosis in vivo: Implications for acute pulmonary inflammation. Am. J. Pathol., 158, 153-161 (2001).
19. Ren Z, Cui J, Huo Z, Xue J, Cui H, Luo B, Jiang L, Yang R. Cordycepin suppresses TNF-a-induced NF-κB activation by reducing p65 transcriptional activity, inhibiting IκBα phosphorylation, and blocking IKKγ ubiquitination. Int. Immunopharmacol., 14, 698-703 (2012).
20. Galani V, Tatsaki E, Bai M, Kitsoulis P, Lekka M, Nakos G, Kanavaros P. The role of apoptosis in the pathophysiology of acute respiratory distress syndrome (ARDS): an up-to-date cell-specific review. Pathol. Res. Pract., 206, 145-150 (2010).
21. Hosakote YM, Liu T, Castro SM, Garofalo RP, Casola A. Respiratory syncytial virus induces oxidative stress by modulating antioxidant enzymes. Am. J. Respir. Cell Mol. Biol., 41, 348-357 (2009).
22. Hoesel B, Schmid JA. The complexity of NF-κB signaling in inflammation and cancer. Mol. Cancer, 12, 86 (2013).
23. Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J. Biol. Chem., 270, 16483-16486 (1995).
24. Yeh CH, Yang JJ, Yang ML, Li YC, Kuan YH. Rutin decreases lipopolysaccharide-induced acute lung injury via inhibition of oxidative stress and the MAPK-NF-κB pathway. Free Radic. Biol. Med., 69, 249-257 (2014).
25. Guo RF, Ward PA. Role of oxidants in lung injury during sepsis. Antioxid. Redox Signal., 9, 1991-2002 (2007).
26. Ashbaugh DG, Boyd Bigelow D, Petty TL, Levine BE. Acute respiratory distress in adults. Lancet, 290, 319-323 (1967).
27. Rhen T, Cidlowski JA. Antiinflammatory action of glucocorticoids-new mechanism for old drugs. N. Engl. J. Med., 353, 1711-1723 (2005).
28. Matthay MA, Zimmerman GA. Acute lung injury and the acute respiratory distresssyndrome: four decades of inquiry into pathogenesis and rational management. Am. J. Respir. Cell Mol. Biol., 33, 319-327 (2005).
29. Zhang X, Huang H, Yang T, Ye Y, Shan J, Yin Z, Luo L. Chlorogenic acid protects mice against lipopolysaccharide-induced acute lung injury. Injury, 41, 746-752 (2010).
30. Xia Z, Triffitt JT. A review on macrophage responses to biomaterials. Biomed. Mater., 1, R1-R9 (2006).
31. Hosakote YM, Liu T, Castro SM, Garofalo RP, Casola A. Respiratory syncytial virus induces oxidative stress by modulating antioxidant enzymes. Am. J. Respir. Cell Mol. Biol., 41, 348-357 (2009).
32. Camacho-Barquero L, Villegas I, Sanchez Calvo JM, Talero E, Sanchez Fidalgo S, Motilva V, Alarcon de la Lastra C. Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and iNOS expression in chronic experimental colitis. Int. Immunopharmacol., 7, 333-342 (2007).
33. Bhatia M, Moochhala S. Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome. J. Pathol., 202, 145-156 (2004).
34. Yoon WJ, Lee NH, Hyun CG. Limonene suppresses lipopolysaccharide-induced production of nitric oxide, prostaglandin E2, andproinflammatory cytokines in RAW 264.7 macrophages. J. Oleo Sci., 59, 415-421 (2010).