Cordycepin suppresses TNF-α-induced NF-κB activation by reducing p65 transcriptional activity, inhibiting IκBα phosphorylation, and blocking IKKγ ubiquitination

International Immunopharmacology

Volumn 14, Issue 4, 2012, Pages 698-703

  Ren, Zhenghua ^a   Cui, Jianhua ^b   Huo, Zeren ^a   Xue, Jinru ^b   Cui, Hao ^c   Luo, Bin ^d   Jiang, Lanjin ^d   Yang, Rirong ^d  

^a SUN YAT SEN UNIVERSITY   (China)

^b JILIN UNIVERSITY   (China)

^c Changchun Central Hospital   (China)

^d GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Cordycepin; I B; IKK; NF B

Indexed keywords

CORDYCEPIN; I KAPPA B; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL NUCLEUS; CELL STRAIN HEK293; DNA BINDING; DOSE RESPONSE; HUMAN; HUMAN CELL; INFLAMMATORY DISEASE; NEOPLASM; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; TRANSCRIPTION INITIATION; UBIQUITINATION;

DEOXYADENOSINES; DOSE-RESPONSE RELATIONSHIP, DRUG; EIF-2 KINASE; GENE EXPRESSION REGULATION; HEK293 CELLS; HELA CELLS; HUMANS; I-KAPPA B KINASE; I-KAPPA B PROTEINS; NF-KAPPA B; PHOSPHORYLATION; PLASMIDS; TUMOR NECROSIS FACTOR-ALPHA; UBIQUITINATION;

EID: 84868221981     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.10.008     Document Type: Article

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