-
1
-
-
80355148374
-
Cognitive and behavioral outcomes after early exposure to anesthesia and surgery
-
Flick RP, Katusic SK, Colligan RC, Wilder RT, Voigt RG, Olson MD, et al. Cognitive and behavioral outcomes after early exposure to anesthesia and surgery. Pediatrics 2011;128:e1053-61.
-
(2011)
Pediatrics
, vol.128
, pp. e1053-e1061
-
-
Flick, RP1
Katusic, SK2
Colligan, RC3
Wilder, RT4
Voigt, RG5
Olson, MD6
-
2
-
-
78650873111
-
General anesthesia, sleep, and coma
-
Brown EN, Lydic R, Schiff ND. General anesthesia, sleep, and coma. N Engl J Med 2010;363:2638-50.
-
(2010)
N Engl J Med
, vol.363
, pp. 2638-2650
-
-
Brown, EN1
Lydic, R2
Schiff, ND.3
-
3
-
-
79952130484
-
Functional connectivity in the brain: Effects of anesthesia
-
Nallasamy N, Tsao DY. Functional connectivity in the brain: Effects of anesthesia. Neuroscientist 2011;17:94-106.
-
(2011)
Neuroscientist
, vol.17
, pp. 94-106
-
-
Nallasamy, N1
Tsao, DY.2
-
4
-
-
77956342625
-
Anesthesia complications during scheduled cesarean delivery for morbidly obese women
-
5
-
Vricella LK, Louis JM, Mercer BM, Bolden N. Anesthesia complications during scheduled cesarean delivery for morbidly obese women. Am J Obstet Gynecol 2010;203:276 e1-5.
-
(2010)
Am J Obstet Gynecol
, vol.203
, pp. 276e1
-
-
Vricella, LK1
Louis, JM2
Mercer, BM3
Bolden, N.4
-
5
-
-
79955474596
-
Postoperative cognitive dysfunction is independent of type of surgery and anesthetic
-
Evered L, Scott DA, Silbert B, Maruff P. Postoperative cognitive dysfunction is independent of type of surgery and anesthetic. Anesth Analg 2011;112:1179-85.
-
(2011)
Anesth Analg
, vol.112
, pp. 1179-1185
-
-
Evered, L1
Scott, DA2
Silbert, B3
Maruff, P.4
-
6
-
-
55849108126
-
Consciousness and anesthesia
-
Alkire MT, Hudetz AG, Tononi G. Consciousness and anesthesia. Science 2008;322:876-80.
-
(2008)
Science
, vol.322
, pp. 876-880
-
-
Alkire, MT1
Hudetz, AG2
Tononi, G.3
-
7
-
-
77955262711
-
New insights into the pathophysiology of postoperative cognitive dysfunction
-
Krenk L, Rasmussen LS, Kehlet H. New insights into the pathophysiology of postoperative cognitive dysfunction. Acta Anaesthesiol Scand 2010;54:951-6.
-
(2010)
Acta Anaesthesiol Scand
, vol.54
, pp. 951-956
-
-
Krenk, L1
Rasmussen, LS2
Kehlet, H.3
-
8
-
-
78650786676
-
Anesthesia-related maternal mortality in the united states: 1979-2002
-
Hawkins JL, Chang J, Palmer SK, Gibbs CP, Callaghan WM. Anesthesia-related maternal mortality in the united states: 1979-2002. Obstet Gynecol 2011;117:69-74.
-
(2011)
Obstet Gynecol
, vol.117
, pp. 69-74
-
-
Hawkins, JL1
Chang, J2
Palmer, SK3
Gibbs, CP4
Callaghan, WM.5
-
9
-
-
65349172340
-
Epidemiology of anesthesia-related mortality in the united states, 1999-2005
-
Li G, Warner M, Lang BH, Huang L, Sun LS. Epidemiology of anesthesia-related mortality in the united states, 1999-2005. Anesthesiology 2009;110:759-65.
-
(2009)
Anesthesiology
, vol.110
, pp. 759-765
-
-
Li, G1
Warner, M2
Lang, BH3
Huang, L4
Sun, LS.5
-
10
-
-
84901008792
-
Targeting pi3k/AKT/mtor signaling in cancer
-
Porta C, Paglino C, Mosca A. Targeting pi3k/AKT/mtor signaling in cancer. Front Oncol 2014;4:64.
-
(2014)
Front Oncol
, vol.4
, pp. 64
-
-
Porta, C1
Paglino, C2
Mosca, A.3
-
11
-
-
77952311165
-
Novel expression patterns of pi3k/AKT/ mtor signaling pathway components in colorectal cancer
-
76-8
-
Johnson SM, Gulhati P, Rampy BA, Han Y, Rychahou PG, Doan HQ, et al. Novel expression patterns of pi3k/AKT/ mtor signaling pathway components in colorectal cancer. J Am Coll Surg 2010;210:767-76, 76-8.
-
(2010)
J Am Coll Surg
, vol.210
, pp. 767-776
-
-
Johnson, SM1
Gulhati, P2
Rampy, BA3
Han, Y4
Rychahou, PG5
Doan, HQ6
-
12
-
-
84937965830
-
Pi3king the lock: Targeting the pi3k/AKT/mtor pathway as a novel therapeutic strategy in neuroblastoma
-
King D, Yeomanson D, Bryant HE. Pi3king the lock: Targeting the pi3k/AKT/mtor pathway as a novel therapeutic strategy in neuroblastoma. J Pediatr Hematol Oncol 2015;37:245-51.
-
(2015)
J Pediatr Hematol Oncol
, vol.37
, pp. 245-251
-
-
King, D1
Yeomanson, D2
Bryant, HE.3
-
13
-
-
43049131769
-
Targeting the pi3k/AKT/mtor pathway: Effective combinations and clinical considerations
-
LoPiccolo J, Blumenthal GM, Bernstein WB, Dennis PA. Targeting the pi3k/AKT/mtor pathway: Effective combinations and clinical considerations. Drug Resist Updat 2008;11:32-50.
-
(2008)
Drug Resist Updat
, vol.11
, pp. 32-50
-
-
LoPiccolo, J1
Blumenthal, GM2
Bernstein, WB3
Dennis, PA.4
-
14
-
-
84983168903
-
Targeting pi3k/AKT/mtor signaling pathway in the treatment of prostate cancer radioresistance
-
Chang L, Graham PH, Ni J, Hao J, Bucci J, Cozzi PJ, et al. Targeting pi3k/AKT/mtor signaling pathway in the treatment of prostate cancer radioresistance. Crit Rev Oncol Hematol 2015;96:507-17.
-
(2015)
Crit Rev Oncol Hematol
, vol.96
, pp. 507-517
-
-
Chang, L1
Graham, PH2
Ni, J3
Hao, J4
Bucci, J5
Cozzi, PJ6
-
15
-
-
51449095342
-
Targeting the pi3k-AKT-mtor pathway: Progress, pitfalls, and promises
-
Yap TA, Garrett MD, Walton MI, Raynaud F, de Bono JS, Workman P. Targeting the pi3k-AKT-mtor pathway: Progress, pitfalls, and promises. Curr Opin Pharmacol 2008;8:393-412.
-
(2008)
Curr Opin Pharmacol
, vol.8
, pp. 393-412
-
-
Yap, TA1
Garrett, MD2
Walton, MI3
Raynaud, F4
de Bono, JS5
Workman, P.6
-
16
-
-
79957983577
-
Targeting the pi3k/AKT/mtor pathway-beyond rapalogs
-
Markman B, Dienstmann R, Tabernero J. Targeting the pi3k/AKT/mtor pathway-beyond rapalogs. Oncotarget 2010;1:530-43. doi: 10.18632/oncotarget.188.
-
(2010)
Oncotarget
, vol.1
, pp. 530-543
-
-
Markman, B1
Dienstmann, R2
Tabernero, J.3
-
17
-
-
38149062059
-
Role of mtor in physiology and pathology of the nervous system
-
Swiech L, Perycz M, Malik A, Jaworski J. Role of mtor in physiology and pathology of the nervous system. Biochim Biophys Acta 2008;1784:116-32.
-
(2008)
Biochim Biophys Acta
, vol.1784
, pp. 116-132
-
-
Swiech, L1
Perycz, M2
Malik, A3
Jaworski, J.4
-
18
-
-
80051982748
-
Critical role of pi3k/AKT/gsk3beta in motoneuron specification from human neural stem cells in response to fgf2 and egf
-
Ojeda L, Gao J, Hooten KG, Wang E, Thonhoff JR, Dunn TJ, et al. Critical role of pi3k/AKT/gsk3beta in motoneuron specification from human neural stem cells in response to fgf2 and egf. PLoS One 2011;6:e23414.
-
(2011)
PLoS One
, vol.6
, pp. e23414
-
-
Ojeda, L1
Gao, J2
Hooten, KG3
Wang, E4
Thonhoff, JR5
Dunn, TJ6
-
19
-
-
34547793039
-
Pi3k/AKT and creb regulate adult neural hippocampal progenitor proliferation and differentiation
-
Peltier J, O'Neill A, Schaffer DV. Pi3k/AKT and creb regulate adult neural hippocampal progenitor proliferation and differentiation. Dev Neurobiol 2007;67:1348-61.
-
(2007)
Dev Neurobiol
, vol.67
, pp. 1348-1361
-
-
Peltier, J1
O'Neill, A2
Schaffer, DV.3
-
20
-
-
75749114797
-
Mtor signaling: At the crossroads of plasticity, memory and disease
-
Hoeffer CA, Klann E. Mtor signaling: At the crossroads of plasticity, memory and disease. Trends Neurosci 2010;33:67-75.
-
(2010)
Trends Neurosci
, vol.33
, pp. 67-75
-
-
Hoeffer, CA1
Klann, E.2
-
21
-
-
3242724040
-
Activation of the phosphoinositide 3-kinase-AKT-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression
-
Hou L, Klann E. Activation of the phosphoinositide 3-kinase-AKT-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression. J Neurosci 2004;24:6352-61.
-
(2004)
J Neurosci
, vol.24
, pp. 6352-6361
-
-
Hou, L1
Klann, E.2
-
23
-
-
4544272020
-
Chronobiological study of the pharmacological response of rats to combination ketamine-midazolam
-
Rebuelto M, Ambros L, Waxman S, Montoya L. Chronobiological study of the pharmacological response of rats to combination ketamine-midazolam. Chronobiol Int 2004;21 (4-5):591-600.
-
(2004)
Chronobiol Int
, vol.21
, Issue.4-5
, pp. 591-600
-
-
Rebuelto, M1
Ambros, L2
Waxman, S3
Montoya, L.4
-
24
-
-
33846461062
-
Morris water maze: Procedures for assessing spatial and related forms of learning and memory
-
Vorhees CV, Williams MT. Morris water maze: Procedures for assessing spatial and related forms of learning and memory. Nat Protoc 2006;1:848-58.
-
(2006)
Nat Protoc
, vol.1
, pp. 848-858
-
-
Vorhees, CV1
Williams, MT.2
-
25
-
-
0033910789
-
Influences of pre- and postnatal nutritional exposures on vascular/endocrine systems in animals
-
Suppl 3
-
Hoet JJ, Ozanne S, Reusens B. Influences of pre- and postnatal nutritional exposures on vascular/endocrine systems in animals. Environ Health Perspect 2000;108 Suppl 3:563-8.
-
(2000)
Environ Health Perspect
, vol.108
, pp. 563-568
-
-
Hoet, JJ1
Ozanne, S2
Reusens, B.3
-
26
-
-
84878153366
-
Preclinical assessment of ketamine
-
Wang C, Liu F, Patterson TA, Paule MG, Slikker W, Jr. Preclinical assessment of ketamine. CNS Neurosci Ther 2013;19:448-53.
-
(2013)
CNS Neurosci Ther
, vol.19
, pp. 448-453
-
-
Wang, C1
Liu, F2
Patterson, TA3
Paule, MG4
Slikker, W5
-
27
-
-
84859457602
-
Ngf promotes cell cycle progression by regulating d-type cyclins via pi3k/akt and mapk/erk activation in human corneal epithelial cells
-
Hong J, Qian T, Le Q, Sun X, Wu J, Chen J, et al. Ngf promotes cell cycle progression by regulating d-type cyclins via pi3k/akt and mapk/erk activation in human corneal epithelial cells. Mol Vis 2012;18:758-64.
-
(2012)
Mol Vis
, vol.18
, pp. 758-764
-
-
Hong, J1
Qian, T2
Le, Q3
Sun, X4
Wu, J5
Chen, J6
-
28
-
-
84864663005
-
Activation of erk1/2 and pi3k/akt by igf-1 on gap-43 expression in drg neurons with excitotoxicity induced by glutamate in vitro
-
Liu Z, Cai H, Zhang P, Li H, Liu H, Li Z. Activation of erk1/2 and pi3k/akt by igf-1 on gap-43 expression in drg neurons with excitotoxicity induced by glutamate in vitro. Cell Mol Neurobiol 2012;32:191-200.
-
(2012)
Cell Mol Neurobiol
, vol.32
, pp. 191-200
-
-
Liu, Z1
Cai, H2
Zhang, P3
Li, H4
Liu, H5
Li, Z.6
-
29
-
-
0025178689
-
Function of myocardial alpha-adrenoceptors
-
Benfey BG. Function of myocardial alpha-adrenoceptors. Life Sci 1990;46:743-57.
-
(1990)
Life Sci
, vol.46
, pp. 743-757
-
-
Benfey, BG.1
-
30
-
-
0346724668
-
Mechanism of action of volatile anesthetics: Role of protein kinase c
-
Gomez RS, Guatimosim C, Gomez MV. Mechanism of action of volatile anesthetics: Role of protein kinase c. Cell Mol Neurobiol 2003;23:877-85.
-
(2003)
Cell Mol Neurobiol
, vol.23
, pp. 877-885
-
-
Gomez, RS1
Guatimosim, C2
Gomez, MV.3
-
31
-
-
84858079914
-
Pi3k/AKT/mtor pathway in angiogenesis
-
Karar J, Maity A. Pi3k/AKT/mtor pathway in angiogenesis. Front Mol Neurosci 2011;4:51.
-
(2011)
Front Mol Neurosci
, vol.4
, pp. 51
-
-
Karar, J1
Maity, A.2
-
32
-
-
84883370400
-
Neuroprotective effect of brain-derived neurotrophic factor mediated by autophagy through the pi3k/AKT/mtor pathway
-
Chen A, Xiong LJ, Tong Y, Mao M. Neuroprotective effect of brain-derived neurotrophic factor mediated by autophagy through the pi3k/AKT/mtor pathway. Mol Med Rep 2013;8:1011-6.
-
(2013)
Mol Med Rep
, vol.8
, pp. 1011-1016
-
-
Chen, A1
Xiong, LJ2
Tong, Y3
Mao, M.4
-
33
-
-
11144335900
-
A new paradigm: Cross talk of protein kinases during reperfusion saves life!
-
Schulz R. A new paradigm: Cross talk of protein kinases during reperfusion saves life! Am J Physiol Heart Circ Physiol 2005;288:H1-2.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.288
, pp. H1-H2
-
-
Schulz, R.1
-
34
-
-
84896401739
-
Molecular targets for cancer therapy in the pi3k/AKT/mtor pathway
-
Polivka J, Jr., Janku F. Molecular targets for cancer therapy in the pi3k/AKT/mtor pathway. Pharmacol Ther 2014;142:164-75.
-
(2014)
Pharmacol Ther
, vol.142
, pp. 164-175
-
-
Polivka, J1
Janku, F.2
-
35
-
-
84899787783
-
Neuropathological role of pi3k/AKT/ mtor axis in down syndrome brain
-
Perluigi M, Pupo G, Tramutola A, Cini C, Coccia R, Barone E, et al. Neuropathological role of pi3k/AKT/ mtor axis in down syndrome brain. Biochim Biophys Acta 2014;1842:1144-53.
-
(2014)
Biochim Biophys Acta
, vol.1842
, pp. 1144-1153
-
-
Perluigi, M1
Pupo, G2
Tramutola, A3
Cini, C4
Coccia, R5
Barone, E6
-
36
-
-
84878831559
-
Overcoming acquired resistance to anticancer therapy: Focus on the pi3k/AKT/mtor pathway
-
Burris HA, 3rd. Overcoming acquired resistance to anticancer therapy: Focus on the pi3k/AKT/mtor pathway. Cancer Chemother Pharmacol 2013;71:829-42.
-
(2013)
Cancer Chemother Pharmacol
, vol.71
, pp. 829-842
-
-
Burris, HA1
-
37
-
-
84879478480
-
Targeting the pi3k/AKT/mtor pathway in castration-resistant prostate cancer
-
Bitting RL, Armstrong AJ. Targeting the pi3k/AKT/mtor pathway in castration-resistant prostate cancer. Endocr Relat Cancer 2013;20:R83-99.
-
(2013)
Endocr Relat Cancer
, vol.20
, pp. R83-R99
-
-
Bitting, RL1
Armstrong, AJ.2
-
38
-
-
58749105333
-
Incidence and risk factors for perioperative hyperglycemia in children with traumatic brain injury
-
Sharma D, Jelacic J, Chennuri R, Chaiwat O, Chandler W, Vavilala MS. Incidence and risk factors for perioperative hyperglycemia in children with traumatic brain injury. Anesth Analg 2009;108:81-9.
-
(2009)
Anesth Analg
, vol.108
, pp. 81-89
-
-
Sharma, D1
Jelacic, J2
Chennuri, R3
Chaiwat, O4
Chandler, W5
Vavilala, MS.6
-
39
-
-
84896856648
-
Folic acid stimulation of neural stem cell proliferation is associated with altered methylation profile of pi3k/akt/creb
-
Yu M, Li W, Luo S, Zhang Y, Liu H, Gao Y, et al. Folic acid stimulation of neural stem cell proliferation is associated with altered methylation profile of pi3k/akt/creb. J Nutr Biochem 2014;25:496-502.
-
(2014)
J Nutr Biochem
, vol.25
, pp. 496-502
-
-
Yu, M1
Li, W2
Luo, S3
Zhang, Y4
Liu, H5
Gao, Y6
-
40
-
-
85101782937
-
S6k promotes dopaminergic neuronal differentiation through pi3k/akt/ mtor-dependent signaling pathways in human neural stem cells. Mol Neurobiol 2015 41 Feliciano DM, Zhang S, Nasrallah CM, Lisgo SN, Bordey A. Embryonic cerebrospinal fluid nanovesicles carry evolutionarily conserved molecules and promote neural stem cell amplification
-
Lee JE, Lim MS, Park JH, Park CH, Koh HC. S6k promotes dopaminergic neuronal differentiation through pi3k/akt/ mtor-dependent signaling pathways in human neural stem cells. Mol Neurobiol 2015 41 Feliciano DM, Zhang S, Nasrallah CM, Lisgo SN, Bordey A. Embryonic cerebrospinal fluid nanovesicles carry evolutionarily conserved molecules and promote neural stem cell amplification. PLoS One 2014;9:e88810.
-
(2014)
PLoS One
, vol.9
, pp. e88810
-
-
Lee, JE1
Lim, MS2
Park, JH3
Park, CH4
Koh, HC.5
-
41
-
-
77749340948
-
Keratinocyte growth factor promotes preadipocyte proliferation via an autocrine mechanism
-
Zhang T, Guan H, Yang K. Keratinocyte growth factor promotes preadipocyte proliferation via an autocrine mechanism. J Cell Biochem 2010;109:737-46.
-
(2010)
J Cell Biochem
, vol.109
, pp. 737-746
-
-
Zhang, T1
Guan, H2
Yang, K.3
-
42
-
-
62149136644
-
Anesthesia, calcium homeostasis and alzheimer's disease
-
Wei H, Xie Z. Anesthesia, calcium homeostasis and alzheimer's disease. Curr Alzheimer Res 2009;6:30-5.
-
(2009)
Curr Alzheimer Res
, vol.6
, pp. 30-35
-
-
Wei, H1
Xie, Z.2
-
43
-
-
84869217593
-
General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex
-
Thrane AS, Rangroo Thrane V, Zeppenfeld D, Lou N, Xu Q, Nagelhus EA, et al. General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex. Proc Natl Acad Sci U S A 2012;109:18974-9.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 18974-18979
-
-
Thrane, AS1
Rangroo Thrane, V2
Zeppenfeld, D3
Lou, N4
Xu, Q5
Nagelhus, EA6
-
45
-
-
77649230770
-
contribution of functional neuroimaging studies to the understanding of the mechanisms of general anesthesia
-
Spe
-
Boveroux P, Bonhomme V, Kirsch M, Noirhomme Q, Ledoux D, Hans G, et al. [contribution of functional neuroimaging studies to the understanding of the mechanisms of general anesthesia]. Rev Med Liege 2009;64 Spec No:36-41.
-
(2009)
Rev Med Liege
, vol.64
, pp. 36-41
-
-
Boveroux, P1
Bonhomme, V2
Kirsch, M3
Noirhomme, Q4
Ledoux, D5
Hans, G6
-
46
-
-
78650873111
-
General anesthesia, sleep, and coma
-
Brown EN, Lydic R, Schiff ND. General anesthesia, sleep, and coma. N Engl J Med 2010;363:2638-50.
-
(2010)
N Engl J Med
, vol.363
, pp. 2638-2650
-
-
Brown, EN1
Lydic, R2
Schiff, ND.3
-
47
-
-
84948165767
-
Effects of anesthesia type on short-term postoperative cognitive function in obstetric patients following cesarean section
-
Altun C, Borazan H, Sahin O, Gezginc K. Effects of anesthesia type on short-term postoperative cognitive function in obstetric patients following cesarean section. J Turk Ger Gynecol Assoc 2015;16:219-25.
-
(2015)
J Turk Ger Gynecol Assoc
, vol.16
, pp. 219-225
-
-
Altun, C1
Borazan, H2
Sahin, O3
Gezginc, K.4
-
48
-
-
78650475179
-
The impact of general and regional anesthesia on the incidence of post-operative cognitive dysfunction and post-operative delirium: A systematic review with meta-analysis
-
Suppl 3
-
Mason SE, Noel-Storr A, Ritchie CW. The impact of general and regional anesthesia on the incidence of post-operative cognitive dysfunction and post-operative delirium: A systematic review with meta-analysis. J Alzheimers Dis 2010;22 Suppl 3:67-79.
-
(2010)
J Alzheimers Dis
, vol.22
, pp. 67-79
-
-
Mason, SE1
Noel-Storr, A2
Ritchie, CW.3
|