Antioxidant and anti-inflammatory activities of the major phenolics from Zygophyllum simplex L.

Journal of Ethnopharmacology

Volumn 205, Issue , 2017, Pages 51-56

  Abdallah, Hossam M ^a,b   Esmat, Ahmed ^c  

^a KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^b CAIRO UNIVERSITY   (Egypt)

^c African Union Organization St Abbassia   (Egypt)

Author keywords

Anti inflammatory; Anti oxidant; Flavonoids; Zygophyllum simplex

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; ISORHAMNETIN; ISORHAMNETIN 3 O BETA DEXTRO GLUCOSIDE; ISORHAMNETIN 3 O BETA DEXTRO RUTINOSIDE; LUTEOLIN 7 GLUCOSIDE; METHANOL; MYRICITRIN; PHENOL DERIVATIVE; PHYTOHEMAGGLUTININ; PLANT EXTRACT; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ZYGOPHYLLUM SIMPLEX EXTRACT; PHYTOCHEMICAL;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; PHYTOCHEMISTRY; ZYGOPHYLLUM; ZYGOPHYLLUM SIMPLEX; AERIAL PLANT PART; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; LYMPHOCYTE;

ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; HUMANS; LYMPHOCYTES; MOLECULAR STRUCTURE; PHENOLS; PHYTOCHEMICALS; PLANT COMPONENTS, AERIAL; ZYGOPHYLLUM;

EID: 85019012902     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2017.04.022     Document Type: Article

References (24)

1. Abdou, A.M., Abdallah, H.M., Mohamed, M.A., Fawzy, G.A., Abdel-Naim, A.B., A new anti-inflammatory triterpene saponin isolated from Anabasis setifera. Arch. Pharmacal Res. 36 (2013), 715–722.
2. Amarowicz, R., Pegg, R., Rahimi-Moghaddam, P., Barl, B., Weil, J., Free-radical scavenging capacity and antioxidant activity of selected plant species from the Canadian prairies. Food Chem. 84 (2004), 551–562.
3. Batanouny, K.H., 1981. Ecology and flora of Qatar. Ecology and Flora of Qatar.
4. Conner, E.M., Grisham, M.B., Inflammation, free radicals, and antioxidants. Nutr 12 (1996), 274–277.
5. Di Carlo, G., Mascolo, N., Izzo, A.A., Capasso, F., Flavonoids: old and new aspects of a class of natural therapeutic drugs. Life Sci. 65 (1999), 337–353.
6. Ezzat, S.M., Abdallah, H.M., Fawzy, G.A., El-Maraghy, S.A., Hepatoprotective constituents of Torilis radiata Moench (Apiaceae). Nat. Prod. Res. 26 (2012), 282–285.
7. Gerritsen, M.E., Carley, W.W., Ranges, G.E., Shen, C.-P., Phan, S.A., Ligon, G.F., Perry, C.A., Flavonoids inhibit cytokine-induced endothelial cell adhesion protein gene expression. Am. J. Pathol., 147, 1995, 278.
8. Hämäläinen, M., Nieminen, R., Vuorela, P., Heinonen, M., Moilanen, E., Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-κ B activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-κ B activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages. Mediat. Inflamm., 2007, 2007.
9. Haroun, S.A., Abualghaith, A.S., Evaluation of the Allelopathic Effect of Aqueous Extract of Zygophyllum simplex L. on Vicia faba L. Plants. Cytologia 80 (2015), 363–371.
10. Hassanean, H., Desoky, E., An acylated isorhamnetin glucoside from Zygophyllum simplex. Phytochemistry 31 (1992), 3293–3294.
11. Ishiwa, J., Sato, T., Mimaki, Y., Sashida, Y., Yano, M., Ito, A., A citrus flavonoid, nobiletin, suppresses production and gene expression of matrix metalloproteinase 9/gelatinase B in rabbit synovial fibroblasts. J. Rheumatol. 27 (2000), 20–25.
12. Kakrani, H.K.N., Kakrani, P.H., Saluja, A.K., Evaluation of analgesic and anti-inflammatory activity of ethyl acetate extract of Zygophyllum simplex Linn. herb. Int. J. Res. Phytochem. Pharmacol. 1 (2011), 180–183.
13. Manna, S.K., Mukhopadhyay, A., Van, N.T., Aggarwal, B.B., Silymarin suppresses TNF-induced activation of NF-κB, c-Jun N-terminal kinase, and apoptosis. J. Immunol. 163 (1999), 6800–6809.
14. Michinori, K., Hideaki, M., Motoharu, T., Yoshiyuki, K., Hiromichi, O., Masayuki, H., Tadato, T., Kensuke, N., Shigeru, A., Studies on Scutellariae radix. VII. anti-arthritic and anti-inflammatory actions of methanolic extract and flavonoid components from Scutellariae radix. Chem. Pharm. Bull. (Tokyo) 32 (1984), 2724–2729.
15. Middleton, E. Jr, Effect of plant flavonoids on immune and inflammatory cell function. Flavonoids in the Living System, 1998, Springer, 175–182.
16. Odontuya, G., Hoult, J., Houghton, P., Structure‐activity relationship for antiinflammatory effect of luteolin and its derived glycosides. Phytother. Res. 19 (2005), 782–786.
17. Santos, A.R., Anti-inflammatory compounds of plant origin. Part II. Modulation of pro-inflammatory cytokines, chemokines and adhesion molecules. Planta Med 70 (2004), 93–103.
18. Schinella, G., Tournier, H., Prieto, J., De Buschiazzo, P.M., Rıos, J., Antioxidant activity of anti-inflammatory plant extracts. Life Sci. 70 (2002), 1023–1033.
19. Shabana, M.M., Ei-Sherei, M.M., Moussa, M.Y., Sleem, A.A., Abdallah, H.M., Flavonoid constituents of Carduncellus mareoticus (Del.) hanelt and their biological activities. Nat. Prod. Commun. 3 (2008), 779–784.
20. Tackholm, V., Drar, M., 1956. Students' flora of Egypt.
21. Tunon, M., Garcia-Mediavilla, M., Sanchez-Campos, S., Gonzalez-Gallego, J., Potential of flavonoids as anti-inflammatory agents: modulation of pro-inflammatory gene expression and signal transduction pathways. Curr. Drug Metab. 10 (2009), 256–271.
22. Virella, G., Litwin, V.M., Immunoserology. Med. Immunol., 2001, 279.
23. Wiart, C., Anti-inflammatory plants. Ethnopharmacol. Med. Plant.: Asia Pac., 2007, 1–55.
24. Xagorari, A., Papapetropoulos, A., Mauromatis, A., Economou, M., Fotsis, T., Roussos, C., Luteolin inhibits an endotoxin-stimulated phosphorylation cascade and proinflammatory cytokine production in macrophages. J. Pharmacol. Exp. Ther. 296 (2001), 181–187.