Use of a central venous line for fluids, drugs and nutrient administration in a mouse model of critical Illness

Journal of Visualized Experiments

Volumn 2017, Issue 123, 2017, Pages

  Derde, Sarah ^a   Thiessen, Steven ^a   Goossens, Chloë ^a   Dufour, Thomas ^a   van den Berghe, Greet ^a   Langouche, Lies ^a  

^a LABORATORY OF MOLECULAR AND CELLULAR SIGNALING   (Belgium)

Author keywords

Catheter; Cecal ligation and puncture; Critical illness; Intensive care; Issue 123; Medicine; Mice; Sepsis

Indexed keywords

DRUG;

ANIMAL; BODY FLUID; C57BL MOUSE; CECUM; CENTRAL VENOUS CATHETERIZATION; CHEMISTRY; CRITICAL ILLNESS; DEVICES; DISEASE MODEL; INDWELLING CATHETER; INTENSIVE CARE; JUGULAR VEIN; LIGATION; MALE; METABOLISM; MOUSE; MULTIPLE ORGAN FAILURE; MUSCLE WEAKNESS; PROCEDURES; PUNCTURE; SURVIVAL ANALYSIS;

ANIMALS; BODY FLUIDS; CATHETERIZATION, CENTRAL VENOUS; CATHETERS, INDWELLING; CECUM; CRITICAL CARE; CRITICAL ILLNESS; DISEASE MODELS, ANIMAL; JUGULAR VEINS; LIGATION; MALE; MICE; MICE, INBRED C57BL; MULTIPLE ORGAN FAILURE; MUSCLE WEAKNESS; PHARMACEUTICAL PREPARATIONS; PUNCTURES; SURVIVAL ANALYSIS;

EID: 85018903770     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/55553     Document Type: Article

References (14)

1. Angus, D. C., & van der Poll, T. Severe sepsis and septic shock. N Engl J Med. 369 (9), 840-851 (2013).
2. Singer, M. et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 315 (8), 801-810 (2016).
3. Remick, D. G., Newcomb, D. E., Bolgos, G. L., & Call, D. R. Comparison of the mortality and inflammatory response of two models of sepsislipopolysaccharide vs. cecal ligation and puncture. Shock. 13 (2), 110-116 (2000).
4. Copeland, S. et al. Acute inflammatory response to endotoxin in mice and humans. Clin Diagn Lab Immunol. 12 (1), 60-67 (2005).
5. Seok, J. et al. Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A. 110 (9), 3507-3512 (2013).
6. Rittirsch, D., Huber-Lang, M. S., Flierl, M. A., & Ward, P. A. Immunodesign of experimental sepsis by cecal ligation and puncture. Nat Protoc. 4 (1), 31-36 (2009).
7. Zolfaghari, P. S., Pinto, B. B., Dyson, A., & Singer, M. The metabolic phenotype of rodent sepsis: cause for concern? Intensive Care Med Exp1 (1), 25 (2013).
8. Radermacher, P., & Haouzi, P. A mouse is not a rat is not a man: species-specific metabolic responses to sepsis - a nail in the coffin of murine models for critical care research? Intensive Care Med Exp. 1 (1), 26 (2013).
9. Dyson, A., & Singer, M. Animal models of sepsis: why does preclinical efficacy fail to translate to the clinical setting? Crit Care Med. 37 (1 Suppl), S30-S37 (2009).
10. Osuchowski, M. F. et al. Abandon the mouse research ship? Not just yet! Shock. 41 (6), 463-475 (2014).
11. Langford DJ1, B. A., Chanda, M.L., Clarke, S.E., Drummond, T.E., Echols, S., Glick, S., Ingrao, J., Klassen-Ross, T., Lacroix-Fralish, M.L., Matsumiya, L., Sorge, R.E., Sotocinal, S.G., Tabaka, J.M., Wong, D., van den Maagdenberg, A.M., Ferrari, M.D., Craig, K.D., Mogil, J.S. Coding of facial expressions of pain in the laboratory mouse. Nat Methods. 7 (2010).
12. Hollenberg, S. M. et al. Characterization of a hyperdynamic murine model of resuscitated sepsis using echocardiography. Am J Respir Crit Care Med. 164 (5), 891-895 (2001).
13. Heuer, J. G. et al. Cecal ligation and puncture with total parenteral nutrition: a clinically relevant model of the metabolic, hormonal, and inflammatory dysfunction associated with critical illness. J Surg Res. 121 (2), 178-186 (2004).
14. Conti, M., Merlani, P., & Ricou, B. Prognosis and quality of life of elderly patients after intensive care. Swiss Med Wkly. 142 w13671 (2012).