Retinal Degeneration in A Mouse Model of CLN5 Disease Is Associated with Compromised Autophagy

Scientific Reports

Volumn 7, Issue 1, 2017, Pages

  Leinonen, Henri ^a,d   Keksa Goldsteine, Velta ^a   Ragauskas, Symantas ^b   Kohlmann, Philip ^a   Singh, Yajuvinder ^a   Savchenko, Ekaterina ^a   Puranen, Jooseppi ^b   Malm, Tarja ^a   Kalesnykas, Giedrius ^b,c   Koistinaho, Jari ^a   Tanila, Heikki ^a   Kanninen, Katja M ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b Experimentica Ltd   (Finland)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLN5 PROTEIN, MOUSE; MEMBRANE PROTEIN;

ANIMAL; APOPTOSIS; AUTOPHAGY; COMPLICATION; DEFICIENCY; DISEASE MODEL; FEMALE; FLUORESCENCE; INFLAMMATION; MACROGLIA; MALE; METABOLISM; MICROGLIA; MOUSE; NEURONAL CEROID LIPOFUSCINOSIS; PATHOLOGY; PATHOPHYSIOLOGY; RETINA DEGENERATION; RETINA ROD; TIME FACTOR; VISUAL ACUITY;

ANIMALS; APOPTOSIS; AUTOPHAGY; DISEASE MODELS, ANIMAL; EPENDYMOGLIAL CELLS; FEMALE; FLUORESCENCE; INFLAMMATION; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICROGLIA; NEURONAL CEROID-LIPOFUSCINOSES; RETINAL DEGENERATION; RETINAL ROD PHOTORECEPTOR CELLS; TIME FACTORS; VISUAL ACUITY;

EID: 85018899417     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-01716-1     Document Type: Article

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