Genotype-Phenotype Correlation of SCN5A Mutation for the Clinical and Electrocardiographic Characteristics of Probands with Brugada Syndrome: A Japanese Multicenter Registry

Circulation

Volumn 135, Issue 23, 2017, Pages 2255-2270

  Yamagata, Kenichiro ^a,c   Horie, Minoru ^b   Aiba, Takeshi ^a   Ogawa, Satoshi ^d   Aizawa, Yoshifusa ^e   Ohe, Tohru ^f   Yamagishi, Masakazu ^g   Makita, Naomasa ^h   Sakurada, Harumizu ⁱ   Tanaka, Toshihiro ^j   Shimizu, Akihiko ^k   Hagiwara, Nobuhisa ^l   Kishi, Ryoji ^m   Nakano, Yukiko ⁿ   Takagi, Masahiko ^o   Makiyama, Takeru ^p   Ohno, Seiko ^b   Fukuda, Keiichi ^d   Watanabe, Hiroshi ^e   Morita, Hiroshi ^f   Hayashi, Kenshi ^g   Kusano, Kengo ^a   Kamakura, Shiro ^a   Yasuda, Satoshi ^a   Ogawa, Hisao ^a   Miyamoto, Yoshihiro ^a   Kapplinger, Jamie D ^q   Ackerman, Michael J ^q   Shimizu, Wataru ^a,r   more..

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d KEIO UNIVERSITY   (Japan)

^e NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^f OKAYAMA UNIVERSITY   (Japan)

^g KANAZAWA UNIVERSITY   (Japan)

^h NAGASAKI UNIVERSITY   (Japan)

ⁱ TOKYO METROPOLITAN HIROO HOSPITAL   (Japan)

^j TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^k YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^l TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^m ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

ⁿ HIROSHIMA UNIVERSITY   (Japan)

^o Osaka Prefecture University   (Japan)

^p KYOTO UNIVERSITY   (Japan)

^q MAYO CLINIC   (United States)

^r NIPPON MEDICAL SCHOOL   (Japan)

more..

Author keywords

Brugada syndrome; Computer similation; Death; Genetic association studies; NAV1.5 voltage gated sodium channel; Risk assessment; Sudden

Indexed keywords

DISOPYRAMIDE; FLECAINIDE; PILSICAINIDE; PROCAINAMIDE; SODIUM CHANNEL BLOCKING AGENT; SODIUM CHANNEL NAV1.5; SCN5A PROTEIN, HUMAN;

ADOLESCENT; ADULT; AGED; ARTICLE; ATRIAL FIBRILLATION; BRUGADA SYNDROME; CARDIOVERSION; CHILD; CLINICAL FEATURE; COMPUTER MODEL; CONTROLLED STUDY; CORONARY ANGIOGRAPHY; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; EVENT FREE SURVIVAL; FAINTNESS; FEMALE; FOLLOW UP; GENE FREQUENCY; GENE MUTATION; GENETIC SCREENING; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HEART ARREST; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HUMAN; IMPLANTABLE CARDIOVERTER DEFIBRILLATOR; LONG QT SYNDROME; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; P WAVE; PHYSICAL EXAMINATION; POLYMORPHIC VENTRICULAR TACHYCARDIA; PQ INTERVAL; PRIORITY JOURNAL; PROGNOSIS; PROVOCATION TEST; QRS COMPLEX; QRS INTERVAL; QT INTERVAL; QTC INTERVAL; REGISTER; RR INTERVAL; SINGLE NUCLEOTIDE POLYMORPHISM; SODIUM CURRENT; THORAX RADIOGRAPHY; CLINICAL TRIAL; GENETICS; GENOTYPE; JAPAN; MIDDLE AGED; MULTICENTER STUDY; MUTATION; PATHOPHYSIOLOGY; PHENOTYPE; PRESCHOOL CHILD; PROCEDURES; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BRUGADA SYNDROME; CHILD; CHILD, PRESCHOOL; ELECTROCARDIOGRAPHY; FEMALE; FOLLOW-UP STUDIES; GENOTYPE; HUMANS; JAPAN; MALE; MIDDLE AGED; MUTATION; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PHENOTYPE; REGISTRIES; YOUNG ADULT;

EID: 85018802794     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.117.027983     Document Type: Article

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