PSD-95 uncoupling from NMDA receptors by Tat- N -dimer ameliorates neuronal depolarization in cortical spreading depression

Journal of Cerebral Blood Flow and Metabolism

Volumn 37, Issue 5, 2017, Pages 1820-1828

  Kucharz, Krzysztof ^a   Søndergaard Rasmussen, Ida ^a   Bach, Anders ^b   Strømgaard, Kristian ^b   Lauritzen, Martin ^a,c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Cortical spreading depression; NMDAR; postsynaptic density protein 95; spreading depolarization; stroke; Tat N dimer; UCCB01 144

Indexed keywords

CELL PENETRATING PEPTIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROPROTECTIVE AGENT; NITRIC OXIDE SYNTHASE; POSTSYNAPTIC DENSITY PROTEIN 95; TAT N DIMER; UNCLASSIFIED DRUG; DLGH4 PROTEIN, MOUSE; GUANYLATE KINASE; MEMBRANE PROTEIN; PEPTIDE; TAT-NPEG4(IETDV)2;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD PH; BRAIN BLOOD FLOW; BRAIN METABOLISM; CARBON DIOXIDE TENSION; CEREBRAL METABOLIC RATE OF OXYGEN; COMPLEX FORMATION; CONTROLLED STUDY; DIRECT CURRENT; ELECTROCORTICOGRAPHY; ELECTROPHYSIOLOGY PARAMETERS; EVOKED RESPONSE OF LOCAL FIELD POTENTIAL; EXCITATORY POSTSYNAPTIC POTENTIAL; FLUORESCENCE MICROSCOPY; GAS ANALYSIS PARAMETERS; MALE; MEAN ARTERIAL PRESSURE; MOUSE; NERVE CELL; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NERVOUS SYSTEM PARAMETERS; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; OXYGEN TENSION; PRESSURE AND TENSION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; SOMATOSENSORY CORTEX; SPREADING CORTICAL DEPRESSION; TISSUE PARTIAL PRESSURE OF OXYGEN; ANIMAL; BRAIN CIRCULATION; C57BL MOUSE; DRUG EFFECTS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SYNAPTIC POTENTIAL;

ANIMALS; BLOOD-BRAIN BARRIER; CEREBROVASCULAR CIRCULATION; CORTICAL SPREADING DEPRESSION; GUANYLATE KINASES; MALE; MEMBRANE PROTEINS; MICE, INBRED C57BL; NEURONS; NEUROPROTECTIVE AGENTS; PEPTIDES; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPTIC POTENTIALS;

EID: 85018764807     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1177/0271678X16645595     Document Type: Article

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