Isomalto-oligosaccharides ameliorate visceral hyperalgesia with repair damage of ileal epithelial ultrastructure in rats

PLoS ONE

Volumn 12, Issue 4, 2017, Pages

  Wang, Weida ^a,e   Xin, Haiwei ^a   Fang, Xiucai ^a   Dou, Hongtao ^a   Liu, Fangyi ^a   Huang, Dan ^b   Han, Shaomei ^c   Fei, Guijun ^a   Zhu, Liming ^a   Zha, Shenghua ^d   Zhang, Hong ^d   Ke, Meiyun ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^b PEOPLE'S HOSPITAL OF GUANGXI ZHUANG AUTONOMOUS REGION   (China)

^c INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^d Beijing Zhongyan Tong Ren Tang Pharmaceutical R d Co Ltd   (China)

^e SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; ISOMALTO OLIGOSACCHARIDE; PLACEBO; PREBIOTIC AGENT; UNCLASSIFIED DRUG;

ABDOMINAL WITHDRAWAL REFLEX; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON DILATATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; FECES CULTURE; FECES MICROFLORA; HYPERALGESIA; ILEUM DISEASE; ILEUM EPITHELIUM; INTESTINE INJURY; INTESTINE TRANSIT TIME; IRRITABLE COLON; MALE; NONHUMAN; PAIN THRESHOLD; PROTEIN BLOOD LEVEL; RAT; SCANNING ELECTRON MICROSCOPY; TREATMENT DURATION; ULTRASTRUCTURE; VISCERAL PAIN; WITHDRAWAL REFLEX; ANIMAL; ANIMAL BEHAVIOR; DISEASE MODEL; DRUG EFFECTS; GASTROINTESTINAL TRANSIT; ILEUM; INTESTINE MUCOSA; MENTAL STRESS; MICROBIOLOGY; TREATMENT OUTCOME; WISTAR RAT;

ANIMALS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; GASTROINTESTINAL TRANSIT; HYPERALGESIA; ILEUM; INTESTINAL MUCOSA; MALE; PREBIOTICS; RATS; RATS, WISTAR; STRESS, PSYCHOLOGICAL; TREATMENT OUTCOME;

EID: 85018588451     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0175276     Document Type: Article

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