Carbon nanotube-anandamide complex exhibits sustained protective effects in an in vitro model of stroke

Physiology and Pharmacology

Volumn 20, Issue 1, 2016, Pages 12-23

  Hassanzadeh, Parichehr ^a,b   Arbabi, Elham ^c   Atyabi, Fatemeh ^a   Dinarvand, Rassoul ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Anandamide; Carbon nanotubes; Ischemic stroke; Oxidative stress

Indexed keywords

ANANDAMIDE; CARBON NANOTUBE; CARBON NANOTUBE ANANDAMIDE COMPLEX; ETHYLENEDIAMINE; GLUTATHIONE; MALONALDEHYDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; CYTOTOXICITY; CYTOTOXICITY ASSAY; DRUG DELIVERY SYSTEM; EXPERIMENTAL STUDY; IMMOBILIZATION; INFRARED SPECTROSCOPY; MTT ASSAY; NONHUMAN; OXIDATIVE STRESS; PC12 CELL LINE; RAT; REOXYGENATION; TRANSMISSION ELECTRON MICROSCOPY;

EID: 85018495619     PISSN: 17350581     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (68)

1. Adinolfi B, Romanini A, Vanni A, Martinotti E, Chicca A, Fogli S, et al. Anticancer activity of anandamide in human cutaneous melanoma cells. Eur J Pharmacol 2013; 718: 154-59.
2. Bhirde AA, Patel V, Gavard J, Zhang G, Sousa AA, Masedunskas A, et al. Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery. ACS Nano 2009; 3: 307-16.
3. Boger DL, Sato H, Lerner AE, Hedrick MP, Fecik RA, Miyauchi H, et al. Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. Proc Natl Acad Sci U S A 2000; 97: 5044-49.
4. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-54.
5. Casanova ML, Blazquez C, Martinez-Palacio J, Villanueva C, Fernandez-Acenero MJ, Huffman JW, et al. Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. J Clin Invest 2003; 111: 43-50.
6. Cellot G, Cilia E, Cipollone S, Rancic V, Sucapane A, Giordani S, et al. Carbon nanotubes might improve neuronal performance by favouring electrical shortcuts. Nat Nanotechnol 2009; 4: 126-33.
7. Cellot G, Toma FM, Varley ZK, Laishram J, Villari A, Quintana M, et al. Carbon nanotube scaffolds tune synaptic strength in cultured neural circuits: novel frontiers in nanomaterial-tissue interactions. J Neurosci 2011; 31: 12945-53.
8. Chen H, Yoshioka H, Kim GS, Jung JE, Okami N, Sakata H, et al. Oxidative stress in ischemic brain damage: mechanisms of cell death and potential molecular targets for neuroprotection. Antioxid Redox Signal 2011; 14: 1505-17.
9. Chen W, Xiong Q, Ren Q, Guo Y, Li G. Can amino-functionalized carbon nanotubes carry functional nerve growth factor? Neural Regen Res 2014; 9: 285-92.
10. Devane WA, Hanus L, Breuer A, Pertwee RG, Stevenson LA, Griffin G, et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 1992; 258: 1946-1949.
11. Di Marzo V, Melck D, Bisogno T, De Petrocellis L. Endocannabinoids: endogenous cannabinoid receptor ligands with neuroremodulatory action. Trends Neurosci 1998; 21: 521-28.
12. Draper HH, Hadley M. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol 1990; 186: 421-31.
13. Eljaschewitsch E, Witting A, Mawrin C, Lee T, Schmidt PM, Wolf S, et al. The endocannabinoid anandamine protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. Neuron 2006; 49: 67-79.
14. Fabbro A, Bosi S, Ballerini L, Prato M. Carbon nanotubes: artificial nanomaterials to engineer single neurons and neuronal networks. ACS Chem Neurosci 2012; 3: 611-18.
15. Fernandez-Ruiz J, Berrendero F, Hernandez ML, Ramos JA. The endogenous cannabinoid system and brain development. Trends Neurosci 2000; 23: 14-20.
16. Gerdeman GL, Lovinger DM. Emerging roles for endocannabinoids in long-term synaptic plasticity. Br J Pharmacol 2003; 140: 781-89.
17. Giuffrida A, Leweke FM, Gerth CW, Schreiber D, Koethe D, Faulhaber J, et al. Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptoms. Neuropsychopharmacology 2004; 29: 2108-14.
18. Gobbi G, Bambico FR, Mangieri R, Bortolato M, Campolongo P, Solinas M, et al. Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. Proc Natl Acad Sci U S A 2005; 102: 18620-25.
19. Green AR, Shuaib A. Therapeutic strategies for the treatment of stroke. Drug Discov Today 2006; 11: 681-93.
20. Hamdi H, De La Torre-Roche R, Hawthorne J, White JC. Impact of non-functionalized and amino-functionalized multiwall carbon nanotubes on pesticide uptake by lettuce (Lactuca sativa L.). Nanotoxicology 2015; 9: 172-80.
21. Hassanzadeh P, Rahimpour S. The cannabinergic system is implicated in the upregulation of central NGF protein by psychotropic drugs. Psychopharmacology 2011; 215: 129-41.
22. 1 receptors mediate the gastroprotective effect of neurotensin. Iran J Basic Med Sci 2012; 15: 803-10.
23. Hassanzadeh P. Computational modelling: Moonlighting on the neuroscience and medicine. Biomed Rev 2013; 24: 25-31.
24. 1 Cannabinoid receptors are involved in neuroleptic-induced enhancement of brain neurotensin. Iran J Basic Med Sci 2014; 17: 181-88.
25. Hassanzadeh P. Nanopharmaceurticals: Innovative theranostics for the neurological disorders. Biomed Rev 2014; 25: 25-34.
26. Hassanzadeh P, Arbabi E, Atyabi F, Dinarvand R. The endocannabinoid system and NGF are involved in the mechanism of action of resveratrol: A multi-target nutraceutical with therapeutic potential in neuropsychiatric disorders. Psychopharmacology 2016; 233: 1087-96.
27. Hayakawa K, Mishima K, Irie K, Hazekawa M, Mishima S, Fujioka M, et al. Cannabidiol prevents a post-ischemic injury progressively induced by cerebral ischemia via a high-mobility group box1-inhibiting mechanism. Neuropharmacology 2008; 55: 1280-86.
28. Iuvone T, Esposito G, Esposito R, Santamaria R, Di Rosa M, Izzo AA. Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on beta-amyloid-induced toxicity in PC12 cells. J Neurochem 2004; 89: 134-41.
29. Jarho P, Urtti A, Pate DW, Suhonen P, Ja¨rvinen T. Increase in aqueous solubility, stability and in vitro corneal permeability of anandamide by hydroxypropyl-ß-cyclodextrin. Int J Pharm 1996; 137: 209-16.
30. Jollow DJ, Mitchell JR, Zampaglione N, Gillette JR. Bromobenze induced liver necrosis: protective role of glutathione and evidence for 3,4-bromobenzenoxide as the hepatotoxic metabolite. Pharmacology 1974; 11: 151–69.
31. Kakkar P, Das B, Viswanathan PN. A modified spectrophotometric assay of superoxide dismutase. Indian J Biochem Biophys 1984; 21: 130-32.
32. Kam NW, Dai H. Carbon nanotubes as intracellular protein transporters: generality and biological functionality. J Am Chem Soc 2005; 127: 6021-26.
33. Klijn CJ, Hankey GJ. Management of acute ischaemic stroke: new guidelines from the American Stroke Association and European Stroke Initiative. Lancet Neurol 2003; 2: 698-701.
34. Larsen EC, Hatcher JF, Adibhatla RM. Effect of tricyclodecan-9-yl potassium xanthate (D609) on phospholipid metabolism and cell death during oxygen– glucose deprivation in PC12 cells. Neuroscience 2007; 146: 946-61.
35. Lavie G, Teichner A, Shohami E, Ovadia H, Leker RR. Long term cerebroprotective effects of dexanabinol in a model of focal cerebral ischemia. Brain Res 2001; 901: 195-201.
36. Lee HJ, Park J, Yoon OJ, Kim HW, Lee do Y, Kim do H, et al. Amine-modified single-walled carbon nanotubes protect neurons from injury in a rat stroke model. Nat Nanotechnol 2011; 6: 121-25.
37. Marsicano G, Moosmann B, Hermann H, Lutz B, Behl C. Neuroprotective Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1. J Neurochem 2002; 80: 448-56.
38. 9THC blocks endocannabinoid-mediated synaptic plasticity. Nat Neurosci 2004; 7: 585-86.
39. Matsumoto K, Sato C, Naka Y, Whitby R, Shimizu N. Stimulation of neuronal neurite outgrowth using functionalized carbon nanotubes. Nanotechnology 2010; 21: 115101.
40. McCormick DA, Contreras D. On the cellular and network bases of epileptic seizures. Annu Rev Physiol 2001; 63: 815-46.
41. McKinney MK, Cravatt BF. Structure and function of fatty acid amide hydrolase. Annu Rev Biochem 2005; 74: 411-32.
42. Mehta SL, Manhas N, Raghubir R. Molecular targets in cerebral ischemia for developing novel therapeutics. Brain Res Rev 2007; 54: 34-66.
43. Milton NG. Anandamide and noladin ether prevent neurotoxicity of the human amyloid-β peptide. Neurosci Lett 2002; 332: 127-30.
44. Mohammadi A, Moghaddam AB, Dinarvand R, Rezaei-Zarchi S. Direct electron transfer of polyphenol oxidase on carbon nanotube surfaces: Application in Biosensing.Int J Electrochem Sci 2009; 4: 895-905.
45. Moskowitz MA, Lo EH, Iadecola C. The science of stroke: mechanisms in search of treatments. Neuron 2010; 67: 181-98.
46. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55-63.
47. Nagayama T, Sinor AD, Simon RP, Chen J, Graham SH, Jin K, et al. Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures. J Neurosci 1999; 19: 2987-95.
48. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351-58.
49. Pacher P, Batkai S, Kunos G. The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev 2006; 58: 389-62.
50. Piomelli D. The molecular logic of endocannabinoid signalling. Nat Rev Neurosci 2003; 4: 873-84.
51. Roman JA, Niedzielko TL, Haddon RC, Parpura V, Floy CL. Single-walled carbon nanotubes chemically functionalized with polyethylene glycol promote tissue repair in a rat model of spinal cord injury. J Neurotrauma 2011; 28: 2349-62.
52. Sancho R, Calzado MA, Di Marzo V, Appendino G, Muñoz E. Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway. Mol Pharmacol 2003; 63: 429-38.
53. Serteser M, Ozben T, Gumuslu S, Balkan S, Balkan E. The effects of NMDA receptor antagonist MK-801 on lipid peroxidation during focal cerebral ischemia in rats. Prog Neuropsychopharmacol Biol Psychiatry 2002; 26: 871-77.
54. Sinor AD, Irvin SM, Greenberg DA. Endocannabinoids protect cerebral cortical neurons from in vitro ischemia in rats. Neurosci Lett 2000; 278: 157-60.
55. Son SJ, Bai X, Nan A, Ghandehari H, Lee SB. Template synthesis of multifunctional nanotubes for controlled release. J Control Release 2006; 114: 143-52.
56. Spitz DR, Sullivan SJ, Malcolm RR, Roberts RJ. Glutathione dependent metabolism and detoxification of 4- hydroxy-2-nonenal. Free Radic Biol Med 1991; 11: 415-23.
57. Sun YP, Fu K, Lin Y, Huang W. Functionalized carbon nanotubes: properties and applications. Acc Chem Res 2002; 35: 1096-104.
58. van der Stelt M, Veldhuis WB, van Haaften GW, Fezza F, Bisogno T, Bar PR, et al., Exogenous anandamide protects rat brain against acute neuronal injury in vivo. J Neurosci 2001; 21: 8765-71.
59. van der Stelt M, Di Marzo V. Cannabinoid receptors and their role in neuroprotection. Neuromolecular Med 2005; 7: 37-50.
60. Walker JM, Krey JF, Chu CJ, Huang SM. Endocannabinoids and related fatty acid derivatives in pain modulation. Chem Phys Lipids 2002; 121: 159-72.
61. Wallace MJ, Martin BR, DeLorenzo RJ. Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity. Eur J Pharmacol 2002; 452: 295-301.
62. Wang J, Sun P, Bao Y, Liu J, An L. Cytotowalled carbon nanotubes on PC12 cells. 2011; 25: 242-50.
63. Warner DS, Sheng H, Batinic-Haberle antioxidants and the ischemic brain. J 207: 3221-31.
64. Whan LB, West MC, McClure N, Lewis SE. tetrahydrocannabinol, the primary cannabinoid in marijuana, on human sperm function in vitro. Fertil Steril 2006; 85: 653-60.
65. Williams EJ, Walsh FS, Doherty P. The FGF receptor uses ignaling system to couple to an e. J Cell Biol 2003; 160: 481-86.
66. Xu L, Sun J, Lu R, Ji Q, Xu JG. Effect of glutamate on inflammatory responses of intestine and brain after focal cerebral ischemia. World J Gastroenterol 2005; 11: 733-36.
67. Zhang S, Uludağ H. Nanoparticulate systems for growth factor delivery. Pharm Res 2009; 26: 1561-80.
68. Zhao D, Alizadeh D, Zhang L, Liu W, Farrukh O, Manuel E, et al. Carbon nanotubes enhance CpG uptake and potentiate antiglioma immunity. Clin Cancer Res 2011; 17: 771-82.