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Volumn 198, Issue 9, 2017, Pages 3548-3557

Scavenger receptor MARCO orchestrates early defenses and contributes to fungal containment during cryptococcal infection

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MACROPHAGE RECEPTOR WITH COLLAGENOUS STRUCTURE RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; SCAVENGER RECEPTOR; UNCLASSIFIED DRUG; IMMUNOGLOBULIN RECEPTOR; MARCO PROTEIN, HUMAN;

EID: 85018487094     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1700057     Document Type: Article
Times cited : (35)

References (46)
  • 1
    • 77955958026 scopus 로고    scopus 로고
    • Mechanisms of cryptococcal virulence and persistence
    • Olszewski, M. A., Y. Zhang, and G. B. Huffnagle. 2010. Mechanisms of cryptococcal virulence and persistence. Future Microbiol. 5: 1269-1288.
    • (2010) Future Microbiol , Issue.5 , pp. 1269-1288
    • Olszewski, M.A.1    Zhang, Y.2    Huffnagle, G.B.3
  • 2
    • 84927725574 scopus 로고    scopus 로고
    • Host immunity to Cryptococcus neoformans
    • Rohatgi, S., and L. A. Pirofski. 2015. Host immunity to Cryptococcus neoformans. Future Microbiol. 10: 565-581.
    • (2015) Future Microbiol , Issue.10 , pp. 565-581
    • Rohatgi, S.1    Pirofski, L.A.2
  • 3
    • 84937884570 scopus 로고    scopus 로고
    • Immunity to Cryptococcus neoformans and C gattii during cryptococcosis
    • Gibson, J. F., and S. A. Johnston. 2015. Immunity to Cryptococcus neoformans and C. gattii during cryptococcosis. Fungal Genet. Biol. 78: 76-86.
    • (2015) Fungal Genet. Biol , Issue.78 , pp. 76-86
    • Gibson, J.F.1    Johnston, S.A.2
  • 4
    • 84936791313 scopus 로고    scopus 로고
    • Is development of a vaccine against Cryptococcus neoformans feasible?
    • Leopold Wager, C. M., and F. L. Wormley, Jr. 2015. Is development of a vaccine against Cryptococcus neoformans feasible? PLoS Pathog. 11: e1004843.
    • (2015) PLoS Pathog , Issue.11 , pp. e1004843
    • Leopold Wager, C.M.1    Wormley, F.L.2
  • 5
    • 84959196715 scopus 로고    scopus 로고
    • Innate host defenses against Cryptococcus neoformans
    • Hole, C., and F. L. Wormley, Jr. 2016. Innate host defenses against Cryptococcus neoformans. J. Microbiol. 54: 202-211.
    • (2016) J. Microbiol , Issue.54 , pp. 202-211
    • Hole, C.1    Wormley, F.L.2
  • 6
    • 76249117469 scopus 로고    scopus 로고
    • Accumulation of CD11b+ lung dendritic cells in response to fungal infection results from the CCR2-mediated recruitment and differentiation of Ly-6Chigh monocytes
    • Osterholzer, J. J., G.-H. Chen, M. A. Olszewski, J. L. Curtis, G. B. Huffnagle, and G. B. Toews. 2009. Accumulation of CD11b+ lung dendritic cells in response to fungal infection results from the CCR2-mediated recruitment and differentiation of Ly-6Chigh monocytes. J. Immunol. 183: 8044-8053.
    • (2009) J. Immunol , vol.183 , pp. 8044-8053
    • Osterholzer, J.J.1    Chen, G.-H.2    Olszewski, M.A.3    Curtis, J.L.4    Huffnagle, G.B.5    Toews, G.B.6
  • 7
    • 47949122479 scopus 로고    scopus 로고
    • CCR2 mediates conventional dendritic cell recruitment and the formation of bronchovascular mononuclear cell infiltrates in the lungs of mice infected with Cryptococcus neoformans
    • Osterholzer, J. J., J. L. Curtis, T. Polak, T. Ames, G. H. Chen, R. McDonald, G. B. Huffnagle, and G. B. Toews. 2008. CCR2 mediates conventional dendritic cell recruitment and the formation of bronchovascular mononuclear cell infiltrates in the lungs of mice infected with Cryptococcus neoformans. J. Immunol. 181: 610-620.
    • (2008) J. Immunol , vol.181 , pp. 610-620
    • Osterholzer, J.J.1    Curtis, J.L.2    Polak, T.3    Ames, T.4    Chen, G.H.5    McDonald, R.6    Huffnagle, G.B.7    Toews, G.B.8
  • 9
    • 79955642451 scopus 로고    scopus 로고
    • Effect of cytokine interplay on macrophage polarization during chronic pulmonary infection with Cryptococcus neoformans
    • Arora, S., M. A. Olszewski, T. M. Tsang, R. A. McDonald, G. B. Toews, and G. B. Huffnagle. 2011. Effect of cytokine interplay on macrophage polarization during chronic pulmonary infection with Cryptococcus neoformans. Infect. Immun. 79: 1915-1926.
    • (2011) Infect. Immun , vol.79 , pp. 1915-1926
    • Arora, S.1    Olszewski, M.A.2    Tsang, T.M.3    McDonald, R.A.4    Toews, G.B.5    Huffnagle, G.B.6
  • 10
    • 79251499275 scopus 로고    scopus 로고
    • Chemokine receptor 2-mediated accumulation of fungicidal exudate macrophages in mice that clear cryptococcal lung infection
    • Osterholzer, J. J., G.-H. Chen, M. A. Olszewski, Y.-M. Zhang, J. L. Curtis, G. B. Huffnagle, and G. B. Toews. 2011. Chemokine receptor 2-mediated accumulation of fungicidal exudate macrophages in mice that clear cryptococcal lung infection. Am. J. Pathol. 178: 198-211.
    • (2011) Am. J. Pathol , Issue.178 , pp. 198-211
    • Osterholzer, J.J.1    Chen, G.-H.2    Olszewski, M.A.3    Zhang, Y.-M.4    Curtis, J.L.5    Huffnagle, G.B.6    Toews, G.B.7
  • 11
    • 84948141154 scopus 로고    scopus 로고
    • Role of dendritic cell-pathogen interactions in the immune response to pulmonary cryptococcal infection
    • Eastman, A. J., J. J. Osterholzer, and M. A. Olszewski. 2015. Role of dendritic cell-pathogen interactions in the immune response to pulmonary cryptococcal infection. Future Microbiol. 10: 1837-1857.
    • (2015) Future Microbiol , vol.10 , pp. 1837-1857
    • Eastman, A.J.1    Osterholzer, J.J.2    Olszewski, M.A.3
  • 12
    • 84896440873 scopus 로고    scopus 로고
    • Defect of CARD9 leads to impaired accumulation of gamma interferon-producing memory phenotype T cells in lungs and increased susceptibility to pulmonary infection with Cryptococcus neoformans
    • Yamamoto, H., Y. Nakamura, K. Sato, Y. Takahashi, T. Nomura, T. Miyasaka, K. Ishii, H. Hara, N. Yamamoto, E. Kanno, et al. 2014. Defect of CARD9 leads to impaired accumulation of gamma interferon-producing memory phenotype T cells in lungs and increased susceptibility to pulmonary infection with Cryptococcus neoformans. Infect. Immun. 82: 1606-1615.
    • (2014) Infect. Immun , Issue.82 , pp. 1606-1615
    • Yamamoto, H.1    Nakamura, Y.2    Sato, K.3    Takahashi, Y.4    Nomura, T.5    Miyasaka, T.6    Ishii, K.7    Hara, H.8    Yamamoto, N.9    Kanno, E.10
  • 13
    • 33847736330 scopus 로고    scopus 로고
    • Protection against cryptococcosis by using a murine gamma interferon-producing Cryptococcus neoformans strain
    • Wormley, F. L. Jr., J. R. Perfect, C. Steele, and G. M. Cox. 2007. Protection against cryptococcosis by using a murine gamma interferon-producing Cryptococcus neoformans strain. Infect. Immun. 75: 1453-1462.
    • (2007) Infect. Immun , vol.75 , pp. 1453-1462
    • Wormley, F.L.1    Perfect, J.R.2    Steele, C.3    Cox, G.M.4
  • 14
    • 84860347125 scopus 로고    scopus 로고
    • Early induction of CCL7 downstream of TLR9 signaling promotes the development of robust immunity to cryptococcal infection
    • Qiu, Y., S. Zeltzer, Y. Zhang, F. Wang, G. H. Chen, J. Dayrit, B. J. Murdock, U. Bhan, G. B. Toews, J. J. Osterholzer, et al. 2012. Early induction of CCL7 downstream of TLR9 signaling promotes the development of robust immunity to cryptococcal infection. J. Immunol. 188: 3940-3948.
    • (2012) J. Immunol , Issue.188 , pp. 3940-3948
    • Qiu, Y.1    Zeltzer, S.2    Zhang, Y.3    Wang, F.4    Chen, G.H.5    Dayrit, J.6    Murdock, B.J.7    Bhan, U.8    Toews, G.B.9    Osterholzer, J.J.10
  • 15
    • 77957285801 scopus 로고    scopus 로고
    • TLR9 signaling is required for generation of the adaptive immune protection in Cryptococcus neoformans-infected lungs
    • Zhang, Y., F. Wang, U. Bhan, G. B. Huffnagle, G. B. Toews, T. J. Standiford, and M. A. Olszewski. 2010. TLR9 signaling is required for generation of the adaptive immune protection in Cryptococcus neoformans-infected lungs. Am. J. Pathol. 177: 754-765.
    • (2010) Am. J. Pathol , Issue.177 , pp. 754-765
    • Zhang, Y.1    Wang, F.2    Bhan, U.3    Huffnagle, G.B.4    Toews, G.B.5    Standiford, T.J.6    Olszewski, M.A.7
  • 16
    • 46249083628 scopus 로고    scopus 로고
    • Role of the mannose receptor in a murine model of Cryptococcus neoformans infection
    • Dan, J. M., R. M. Kelly, C. K. Lee, and S. M. Levitz. 2008. Role of the mannose receptor in a murine model of Cryptococcus neoformans infection. Infect. Immun. 76: 2362-2367.
    • (2008) Infect. Immun , vol.76 , pp. 2362-2367
    • Dan, J.M.1    Kelly, R.M.2    Lee, C.K.3    Levitz, S.M.4
  • 17
    • 67650102353 scopus 로고    scopus 로고
    • Scavenger receptors: Role in innate immunity and microbial pathogenesis
    • Areschoug, T., and S. Gordon. 2009. Scavenger receptors: role in innate immunity and microbial pathogenesis. Cell. Microbiol. 11: 1160-1169.
    • (2009) Cell. Microbiol , vol.11 , pp. 1160-1169
    • Areschoug, T.1    Gordon, S.2
  • 18
    • 67650904929 scopus 로고    scopus 로고
    • TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis
    • MARCO
    • Bowdish, D. M., K. Sakamoto, M.-J. Kim, M. Kroos, S. Mukhopadhyay, C. A. Leifer, K. Tryggvason, S. Gordon, and D. G. Russell. 2009. MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis. PLoS Pathog. 5: e1000474.
    • (2009) PLoS Pathog , vol.5 , pp. e1000474
    • Bowdish, D.M.1    Sakamoto, K.2    Kim, M.-J.3    Kroos, M.4    Mukhopadhyay, S.5    Leifer, C.A.6    Tryggvason, K.7    Gordon, S.8    Russell, D.G.9
  • 19
    • 84871825753 scopus 로고    scopus 로고
    • MARCO is required for TLR2-And Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx
    • Dorrington, M. G., A. M. Roche, S. E. Chauvin, Z. Tu, K. L. Mossman, J. N. Weiser, and D. M. Bowdish. 2013. MARCO is required for TLR2-And Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx. J. Immunol. 190: 250-258.
    • (2013) J. Immunol , Issue.190 , pp. 250-258
    • Dorrington, M.G.1    Roche, A.M.2    Chauvin, S.E.3    Tu, Z.4    Mossman, K.L.5    Weiser, J.N.6    Bowdish, D.M.7
  • 20
    • 3242782480 scopus 로고    scopus 로고
    • The scavenger receptor MARCO is required for lung defense against pneumococcal pneumonia and inhaled particles
    • Arredouani, M., Z. Yang, Y. Ning, G. Qin, R. Soininen, K. Tryggvason, and L. Kobzik. 2004. The scavenger receptor MARCO is required for lung defense against pneumococcal pneumonia and inhaled particles. J. Exp. Med. 200: 267-272.
    • (2004) J. Exp. Med , vol.200 , pp. 267-272
    • Arredouani, M.1    Yang, Z.2    Ning, Y.3    Qin, G.4    Soininen, R.5    Tryggvason, K.6    Kobzik, L.7
  • 22
    • 84955473949 scopus 로고    scopus 로고
    • A single-cell gene-expression profile reveals inter-cellular heterogeneity within human monocyte subsets
    • Gren, S. T., T. B. Rasmussen, S. Janciauskiene, K. Hakansson, J. G. Gerwien, and O. Grip. 2015. A single-cell gene-expression profile reveals inter-cellular heterogeneity within human monocyte subsets. PLoS One 10: e0144351.
    • (2015) PLoS One , vol.10 , pp. e0144351
    • Gren, S.T.1    Rasmussen, T.B.2    Janciauskiene, S.3    Hakansson, K.4    Gerwien, J.G.5    Grip, O.6
  • 24
    • 84857626526 scopus 로고    scopus 로고
    • Scavenger receptors and b-glucan receptors participate in the recognition of yeasts by murine macrophages
    • Józefowski, S., Z. Yang, J. Marcinkiewicz, and L. Kobzik. 2012. Scavenger receptors and b-glucan receptors participate in the recognition of yeasts by murine macrophages. Inflamm. Res. 61: 113-126.
    • (2012) Inflamm. Res , vol.61 , pp. 113-126
    • Józefowski, S.1    Yang, Z.2    Marcinkiewicz, J.3    Kobzik, L.4
  • 25
    • 0038783458 scopus 로고    scopus 로고
    • Identification of uteroglobin-related protein 1 and macrophage scavenger receptor with collagenous structure as a lung-specific ligand-receptor pair
    • Bin, L.-H., L. D. Nielson, X. Liu, R. J. Mason, and H.-B. Shu. 2003. Identification of uteroglobin-related protein 1 and macrophage scavenger receptor with collagenous structure as a lung-specific ligand-receptor pair. J. Immunol. 171: 924-930.
    • (2003) J. Immunol , vol.171 , pp. 924-930
    • Bin, L.-H.1    Nielson, L.D.2    Liu, X.3    Mason, R.J.4    Shu, H.-B.5
  • 26
    • 0034541230 scopus 로고    scopus 로고
    • The role of macrophage inflammatory protein-1a/CCL3 in regulation of T cell-mediated immunity to Cryptococcus neoformans infection
    • Olszewski, M. A., G. B. Huffnagle, R. A. McDonald, D. M. Lindell, B. B. Moore, D. N. Cook, and G. B. Toews. 2000. The role of macrophage inflammatory protein-1a/CCL3 in regulation of T cell-mediated immunity to Cryptococcus neoformans infection. J. Immunol. 165: 6429-6436.
    • (2000) J. Immunol , vol.165 , pp. 6429-6436
    • Olszewski, M.A.1    Huffnagle, G.B.2    McDonald, R.A.3    Lindell, D.M.4    Moore, B.B.5    Cook, D.N.6    Toews, G.B.7
  • 27
  • 28
    • 84876361438 scopus 로고    scopus 로고
    • Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections
    • Guilliams, M., B. N. Lambrecht, and H. Hammad. 2013. Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections. Mucosal Immunol. 6: 464-473.
    • (2013) Mucosal Immunol , Issue.6 , pp. 464-473
    • Guilliams, M.1    Lambrecht, B.N.2    Hammad, H.3
  • 29
    • 84883158032 scopus 로고    scopus 로고
    • Scavenger receptors in homeostasis and immunity
    • Canton, J., D. Neculai, and S. Grinstein. 2013. Scavenger receptors in homeostasis and immunity. Nat. Rev. Immunol. 13: 621-634.
    • (2013) Nat. Rev. Immunol , Issue.13 , pp. 621-634
    • Canton, J.1    Neculai, D.2    Grinstein, S.3
  • 30
    • 0029128980 scopus 로고
    • Down-regulation of the afferent phase of T cell-mediated pulmonary inflammation and immunity by a high melanin-producing strain of Cryptococcus neoformans
    • Huffnagle, G. B., G. H. Chen, J. L. Curtis, R. A. McDonald, R. M. Strieter, and G. B. Toews. 1995. Down-regulation of the afferent phase of T cell-mediated pulmonary inflammation and immunity by a high melanin-producing strain of Cryptococcus neoformans. J. Immunol. 155: 3507-3516.
    • (1995) J. Immunol , vol.155 , pp. 3507-3516
    • Huffnagle, G.B.1    Chen, G.H.2    Curtis, J.L.3    McDonald, R.A.4    Strieter, R.M.5    Toews, G.B.6
  • 32
    • 84986568013 scopus 로고    scopus 로고
    • Disruption of early tumor necrosis factor alpha signaling prevents classical activation of dendritic cells in lung-Associated lymph nodes and development of protective immunity against cryptococcal infection
    • Xu, J., A. J. Eastman, A. Flaczyk, L. M. Neal, G. Zhao, J. Carolan, A. N. Malachowski, V. R. Stolberg, M. Yosri, S. W. Chensue, et al. 2016. Disruption of early tumor necrosis factor alpha signaling prevents classical activation of dendritic cells in lung-Associated lymph nodes and development of protective immunity against cryptococcal infection. MBio 7: e00510-16.
    • (2016) MBio , vol.7 , pp. e00510-e00516
    • Xu, J.1    Eastman, A.J.2    Flaczyk, A.3    Neal, L.M.4    Zhao, G.5    Carolan, J.6    Malachowski, A.N.7    Stolberg, V.R.8    Yosri, M.9    Chensue, S.W.10
  • 34
    • 84906348057 scopus 로고    scopus 로고
    • Classical versus alternative macrophage activation: The Ying and the Yang in host defense against pulmonary fungal infections
    • Leopold Wager, C. M., and F. L. Wormley, Jr. 2014. Classical versus alternative macrophage activation: The Ying and the Yang in host defense against pulmonary fungal infections. Mucosal Immunol. 7: 1023-1035.
    • (2014) Mucosal Immunol , Issue.7 , pp. 1023-1035
    • Leopold Wager, C.M.1    Wormley, F.L.2
  • 35
    • 15544372839 scopus 로고    scopus 로고
    • The gamma interferon receptor is required for the protective pulmonary inflammatory response to Cryptococcus neoformans
    • Chen, G.-H., R. A. McDonald, J. C. Wells, G. B. Huffnagle, N. W. Lukacs, and G. B. Toews. 2005. The gamma interferon receptor is required for the protective pulmonary inflammatory response to Cryptococcus neoformans. Infect. Immun. 73: 1788-1796.
    • (2005) Infect. Immun , vol.73 , pp. 1788-1796
    • Chen, G.-H.1    McDonald, R.A.2    Wells, J.C.3    Huffnagle, G.B.4    Lukacs, N.W.5    Toews, G.B.6
  • 37
    • 84879562515 scopus 로고    scopus 로고
    • Macrophage M1/M2 polarization dynamically adapts to changes in cytokine microenvironments in Cryptococcus neoformans infection
    • Davis, M. J., T. M. Tsang, Y. Qiu, J. K. Dayrit, J. B. Freij, G. B. Huffnagle, and M. A. Olszewski. 2013. Macrophage M1/M2 polarization dynamically adapts to changes in cytokine microenvironments in Cryptococcus neoformans infection. MBio 4: e00264-13.
    • (2013) MBio , vol.4 , pp. e00264-e00313
    • Davis, M.J.1    Tsang, T.M.2    Qiu, Y.3    Dayrit, J.K.4    Freij, J.B.5    Huffnagle, G.B.6    Olszewski, M.A.7
  • 38
    • 85191983349 scopus 로고    scopus 로고
    • From monocytes to M1/M2 macrophages: Phenotypical vs functional differentiation
    • Italiani, P., and D. Boraschi. 2014. From monocytes to M1/M2 macrophages: phenotypical vs. functional differentiation. Front. Immunol. 5: 514.
    • (2014) Front. Immunol , vol.5 , pp. 514
    • Italiani, P.1    Boraschi, D.2
  • 40
    • 67649394036 scopus 로고    scopus 로고
    • SR-A, MARCO and TLRs differentially recognise selected surface proteins from Neisseria meningitidis: An example of fine specificity in microbial ligand recognition by innate immune receptors
    • Plüddemann, A., S. Mukhopadhyay, M. Sankala, S. Savino, M. Pizza, R. Rappuoli, K. Tryggvason, and S. Gordon. 2009. SR-A, MARCO and TLRs differentially recognise selected surface proteins from Neisseria meningitidis: An example of fine specificity in microbial ligand recognition by innate immune receptors. J. Innate Immun. 1: 153-163.
    • (2009) J. Innate Immun , vol.1 , pp. 153-163
    • Plüddemann, A.1    Mukhopadhyay, S.2    Sankala, M.3    Savino, S.4    Pizza, M.5    Rappuoli, R.6    Tryggvason, K.7    Gordon, S.8
  • 41
    • 0034651769 scopus 로고    scopus 로고
    • CCR2 expression determines T1 versus T2 polarization during pulmonary Cryptococcus neoformans infection
    • Traynor, T. R., W. A. Kuziel, G. B. Toews, and G. B. Huffnagle. 2000. CCR2 expression determines T1 versus T2 polarization during pulmonary Cryptococcus neoformans infection. J. Immunol. 164: 2021-2027.
    • (2000) J. Immunol , vol.164 , pp. 2021-2027
    • Traynor, T.R.1    Kuziel, W.A.2    Toews, G.B.3    Huffnagle, G.B.4
  • 42
    • 0036569787 scopus 로고    scopus 로고
    • Differential roles of CC chemokine ligand 2/monocyte chemotactic protein-1 and CCR2 in the development of T1 immunity
    • Traynor, T. R., A. C. Herring, M. E. Dorf, W. A. Kuziel, G. B. Toews, and G. B. Huffnagle. 2002. Differential roles of CC chemokine ligand 2/monocyte chemotactic protein-1 and CCR2 in the development of T1 immunity. J. Immunol. 168: 4659-4666.
    • (2002) J. Immunol , vol.168 , pp. 4659-4666
    • Traynor, T.R.1    Herring, A.C.2    Dorf, M.E.3    Kuziel, W.A.4    Toews, G.B.5    Huffnagle, G.B.6
  • 43
    • 42649108339 scopus 로고    scopus 로고
    • Monocyte-mediated defense against microbial pathogens
    • Serbina, N. V., T. Jia, T. M. Hohl, and E. G. Pamer. 2008. Monocyte-mediated defense against microbial pathogens. Annu. Rev. Immunol. 26: 421-452.
    • (2008) Annu. Rev. Immunol , vol.26 , pp. 421-452
    • Serbina, N.V.1    Jia, T.2    Hohl, T.M.3    Pamer, E.G.4
  • 44
    • 34547627853 scopus 로고    scopus 로고
    • Scavenger receptor A dampens induction of inflammation in response to the fungal pathogen Pneumocystis carinii
    • Hollifield, M., E. Bou Ghanem, W. J. de Villiers, and B. A. Garvy. 2007. Scavenger receptor A dampens induction of inflammation in response to the fungal pathogen Pneumocystis carinii. Infect. Immun. 75: 3999-4005.
    • (2007) Infect. Immun , vol.75 , pp. 3999-4005
    • Hollifield, M.1    Bou Ghanem, E.2    De Villiers, W.J.3    Garvy, B.A.4
  • 45
    • 0030588635 scopus 로고    scopus 로고
    • Afferent phase production of TNF-Alpha is required for the development of protective T cell immunity to Cryptococcus neoformans
    • Huffnagle, G. B., G. B. Toews, M. D. Burdick, M. B. Boyd, K. S. McAllister, R. A. McDonald, S. L. Kunkel, and R. M. Strieter. 1996. Afferent phase production of TNF-Alpha is required for the development of protective T cell immunity to Cryptococcus neoformans. J. Immunol. 157: 4529-4536.
    • (1996) J. Immunol , vol.157 , pp. 4529-4536
    • Huffnagle, G.B.1    Toews, G.B.2    Burdick, M.D.3    Boyd, M.B.4    McAllister, K.S.5    McDonald, R.A.6    Kunkel, S.L.7    Strieter, R.M.8
  • 46
    • 0031310135 scopus 로고    scopus 로고
    • IL-12 and IFN-g are required for initiating the protective Th1 response to pulmonary cryptococcosis in resistant C.B-17 mice
    • Hoag, K. A., M. F. Lipscomb, A. A. Izzo, and N. E. Street. 1997. IL-12 and IFN-g are required for initiating the protective Th1 response to pulmonary cryptococcosis in resistant C.B-17 mice. Am. J. Respir. Cell Mol. Biol. 17: 733-739.
    • (1997) Am. J. Respir. Cell Mol. Biol , vol.17 , pp. 733-739
    • Hoag, K.A.1    Lipscomb, M.F.2    Izzo, A.A.3    Street, N.E.4


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