메뉴 건너뛰기




Volumn 13, Issue 4, 2017, Pages

Phenome-wide heritability analysis of the UK Biobank

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BIOBANK; BLOOD PRESSURE; BODY HEIGHT; BODY MASS; EDUCATION; FEMALE; GENETIC TRAIT; GENETIC VARIATION; HERITABILITY; HUMAN; MALE; PHENOTYPE; QUANTITATIVE TRAIT; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SOCIAL STATUS; UNITED KINGDOM; GENETIC DISORDER; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE ENVIRONMENT INTERACTION; MIDDLE AGED; SEXUAL DEVELOPMENT; SOCIAL CLASS;

EID: 85018389876     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1006711     Document Type: Article
Times cited : (158)

References (75)
  • 1
    • 40849097776 scopus 로고    scopus 로고
    • Heritability in the genomics era—concepts and misconceptions
    • 18319743
    • Visscher P. M., Hill W. G., Wray N. R., (2008). Heritability in the genomics era—concepts and misconceptions. Nature Reviews Genetics, 9(4), 255–266. doi: 10.1038/nrg2322 18319743
    • (2008) Nature Reviews Genetics , vol.9 , Issue.4 , pp. 255-266
    • Visscher, P.M.1    Hill, W.G.2    Wray, N.R.3
  • 2
    • 84933279742 scopus 로고    scopus 로고
    • Meta-analysis of the heritability of human traits based on fifty years of twin studies
    • 25985137
    • Polderman T. J., Benyamin B., De Leeuw C. A., Sullivan P. F., Van Bochoven A., Visscher P. M., et al. (2015). Meta-analysis of the heritability of human traits based on fifty years of twin studies. Nature Genetics, 47(7), 702–709. doi: 10.1038/ng.3285 25985137
    • (2015) Nature Genetics , vol.47 , Issue.7 , pp. 702-709
    • Polderman, T.J.1    Benyamin, B.2    De Leeuw, C.A.3    Sullivan, P.F.4    Van Bochoven, A.5    Visscher, P.M.6
  • 3
    • 79952489475 scopus 로고    scopus 로고
    • Estimating missing heritability for disease from genome-wide association studies
    • 21376301
    • Lee S. H., Wray N. R., Goddard M. E., Visscher P. M., (2011). Estimating missing heritability for disease from genome-wide association studies. The American Journal of Human Genetics, 88(3), 294–305. doi: 10.1016/j.ajhg.2011.02.002 21376301
    • (2011) The American Journal of Human Genetics , vol.88 , Issue.3 , pp. 294-305
    • Lee, S.H.1    Wray, N.R.2    Goddard, M.E.3    Visscher, P.M.4
  • 4
    • 77954140531 scopus 로고    scopus 로고
    • Common SNPs explain a large proportion of the heritability for human height
    • 20562875
    • Yang J., Benyamin B., McEvoy B. P., Gordon S., Henders A. K., Nyholt D. R., et al. (2010). Common SNPs explain a large proportion of the heritability for human height. Nature Genetics, 42(7), 565–569. doi: 10.1038/ng.608 20562875
    • (2010) Nature Genetics , vol.42 , Issue.7 , pp. 565-569
    • Yang, J.1    Benyamin, B.2    McEvoy, B.P.3    Gordon, S.4    Henders, A.K.5    Nyholt, D.R.6
  • 6
    • 0346361698 scopus 로고    scopus 로고
    • Socioeconomic status modifies heritability of IQ in young children
    • 14629696
    • Turkheimer E., Haley A., Waldron M., D'Onofrio B., Gottesman I. I., (2003). Socioeconomic status modifies heritability of IQ in young children. Psychological Science, 14(6), 623–628. doi: 10.1046/j.0956-7976.2003.psci_1475.x 14629696
    • (2003) Psychological Science , vol.14 , Issue.6 , pp. 623-628
    • Turkheimer, E.1    Haley, A.2    Waldron, M.3    D'Onofrio, B.4    Gottesman, I.I.5
  • 7
    • 84926430250 scopus 로고    scopus 로고
    • UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age
    • 25826379
    • Sudlow C., Gallacher J., Allen N., Beral V., Burton P., Danesh J., et al. (2015). UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age. PLoS Medicine, 12(3), e1001779. doi: 10.1371/journal.pmed.1001779 25826379
    • (2015) PLoS Medicine , vol.12 , Issue.3 , pp. e1001779
    • Sudlow, C.1    Gallacher, J.2    Allen, N.3    Beral, V.4    Burton, P.5    Danesh, J.6
  • 8
    • 84923946495 scopus 로고    scopus 로고
    • LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
    • 25642630
    • Bulik-Sullivan B. K., Loh P. R., Finucane H. K., Ripke S., Yang J., Patterson N., et al. (2015). LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nature Genetics, 47(3), 291–295. doi: 10.1038/ng.3211 25642630
    • (2015) Nature Genetics , vol.47 , Issue.3 , pp. 291-295
    • Bulik-Sullivan, B.K.1    Loh, P.R.2    Finucane, H.K.3    Ripke, S.4    Yang, J.5    Patterson, N.6
  • 9
    • 84965076156 scopus 로고    scopus 로고
    • Developing and evaluating polygenic risk prediction models for stratified disease prevention
    • 27140283
    • Chatterjee N., Shi J., García-Closas M., (2016). Developing and evaluating polygenic risk prediction models for stratified disease prevention. Nature Reviews Genetics, 17(7), 392–406. doi: 10.1038/nrg.2016.27 27140283
    • (2016) Nature Reviews Genetics , vol.17 , Issue.7 , pp. 392-406
    • Chatterjee, N.1    Shi, J.2    García-Closas, M.3
  • 10
    • 84916623158 scopus 로고    scopus 로고
    • Measuring missing heritability: inferring the contribution of common variants
    • Golan D., Lander E. S., Rosset S., (2014). Measuring missing heritability: inferring the contribution of common variants. Proceedings of the National Academy of Sciences, 111(49), E5272–E5281.
    • (2014) Proceedings of the National Academy of Sciences , vol.111 , Issue.49 , pp. E5272-E5281
    • Golan, D.1    Lander, E.S.2    Rosset, S.3
  • 11
    • 85000443086 scopus 로고    scopus 로고
    • Partitioning heritability by functional annotation using genome-wide association summary statistics
    • 26414678
    • Finucane H. K., Bulik-Sullivan B., Gusev A., Trynka G., Reshef Y., Loh P. R., et al. (2015). Partitioning heritability by functional annotation using genome-wide association summary statistics. Nature Genetics, 47(11), 1228–1235. doi: 10.1038/ng.3404 26414678
    • (2015) Nature Genetics , vol.47 , Issue.11 , pp. 1228-1235
    • Finucane, H.K.1    Bulik-Sullivan, B.2    Gusev, A.3    Trynka, G.4    Reshef, Y.5    Loh, P.R.6
  • 13
    • 85009844693 scopus 로고    scopus 로고
    • LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis
    • . ., btw613
    • Zheng J., Erzurumluoglu A. M., Elsworth B. L., Kemp J. P., Howe L., Haycock P. C., et al. (2016). LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis. Bioinformatics, btw613.
    • (2016) Bioinformatics
    • Zheng, J.1    Erzurumluoglu, A.M.2    Elsworth, B.L.3    Kemp, J.P.4    Howe, L.5    Haycock, P.C.6
  • 14
    • 0033949377 scopus 로고    scopus 로고
    • Haseman and Elston revisited
    • 10861893
    • Elston R. C., Buxbaum S., Jacobs K. B., Olson J. M., (2000). Haseman and Elston revisited. Genetic Epidemiology, 19(1), 1–17. doi: 10.1002/1098-2272(200007)19:1<1::AID-GEPI1>3.0.CO;2-E 10861893
    • (2000) Genetic Epidemiology , vol.19 , Issue.1 , pp. 1-17
    • Elston, R.C.1    Buxbaum, S.2    Jacobs, K.B.3    Olson, J.M.4
  • 15
    • 0015309467 scopus 로고
    • The investigation of linkage between a quantitative trait and a marker locus
    • 4157472
    • Haseman J. K., Elston R. C., (1972). The investigation of linkage between a quantitative trait and a marker locus. Behavior Genetics, 2(1), 3–19. 4157472
    • (1972) Behavior Genetics , vol.2 , Issue.1 , pp. 3-19
    • Haseman, J.K.1    Elston, R.C.2
  • 16
    • 0034987802 scopus 로고    scopus 로고
    • Equivalence between Haseman-Elston and variance-components linkage analyses for sib pairs
    • 11353401
    • Sham P. C., Purcell S., (2001). Equivalence between Haseman-Elston and variance-components linkage analyses for sib pairs. The American Journal of Human Genetics, 68(6), 1527–1532. doi: 10.1086/320593 11353401
    • (2001) The American Journal of Human Genetics , vol.68 , Issue.6 , pp. 1527-1532
    • Sham, P.C.1    Purcell, S.2
  • 17
    • 84901380413 scopus 로고    scopus 로고
    • Statistical power to detect genetic (co) variance of complex traits using SNP data in unrelated samples
    • 24721987
    • Visscher P. M., Hemani G., Vinkhuyzen A. A., Chen G. B., Lee S. H., Wray N. R., et al. (2014). Statistical power to detect genetic (co) variance of complex traits using SNP data in unrelated samples. PLoS Genetics, 10(4), e1004269. doi: 10.1371/journal.pgen.1004269 24721987
    • (2014) PLoS Genetics , vol.10 , Issue.4 , pp. e1004269
    • Visscher, P.M.1    Hemani, G.2    Vinkhuyzen, A.A.3    Chen, G.B.4    Lee, S.H.5    Wray, N.R.6
  • 19
    • 33750544922 scopus 로고    scopus 로고
    • Bias, precision and heritability of self-reported and clinically measured height in Australian twins
    • 16933140
    • MacGregor S., Cornes B. K., Martin N. G., Visscher P. M., (2006). Bias, precision and heritability of self-reported and clinically measured height in Australian twins. Human Genetics, 120(4), 571–580. doi: 10.1007/s00439-006-0240-z 16933140
    • (2006) Human Genetics , vol.120 , Issue.4 , pp. 571-580
    • MacGregor, S.1    Cornes, B.K.2    Martin, N.G.3    Visscher, P.M.4
  • 20
    • 43249106445 scopus 로고    scopus 로고
    • Heritability of body size and muscle strength in young adulthood: a study of one million Swedish men
    • 18271028
    • Silventoinen K., Magnusson P. K., Tynelius P., Kaprio J., Rasmussen F., (2008). Heritability of body size and muscle strength in young adulthood: a study of one million Swedish men. Genetic Epidemiology, 32(4), 341–349. doi: 10.1002/gepi.20308 18271028
    • (2008) Genetic Epidemiology , vol.32 , Issue.4 , pp. 341-349
    • Silventoinen, K.1    Magnusson, P.K.2    Tynelius, P.3    Kaprio, J.4    Rasmussen, F.5
  • 21
    • 9144254700 scopus 로고    scopus 로고
    • Heritability of adult body height: a comparative study of twin cohorts in eight countries
    • Silventoinen K., Sammalisto S., Perola M., Boomsma D. I., Cornes B. K., Davis C., et al. (2003). Heritability of adult body height: a comparative study of twin cohorts in eight countries. Twin Research, 6(05), 399–408.
    • (2003) Twin Research , vol.6 , Issue.5 , pp. 399-408
    • Silventoinen, K.1    Sammalisto, S.2    Perola, M.3    Boomsma, D.I.4    Cornes, B.K.5    Davis, C.6
  • 22
    • 79957456397 scopus 로고    scopus 로고
    • From Galton to GWAS: quantitative genetics of human height
    • 21429269
    • Visscher P. M., McEvoy B., Yang J., (2010). From Galton to GWAS: quantitative genetics of human height. Genetics Research, 92, 371–379. doi: 10.1017/S0016672310000571 21429269
    • (2010) Genetics Research , vol.92 , pp. 371-379
    • Visscher, P.M.1    McEvoy, B.2    Yang, J.3
  • 23
    • 84878502589 scopus 로고    scopus 로고
    • Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits
    • 23737753
    • Zaitlen N., Kraft P., Patterson N., Pasaniuc B., Bhatia G., Pollack S., et al. (2013). Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits. PLoS Genetics, 9(5), e1003520. doi: 10.1371/journal.pgen.1003520 23737753
    • (2013) PLoS Genetics , vol.9 , Issue.5 , pp. e1003520
    • Zaitlen, N.1    Kraft, P.2    Patterson, N.3    Pasaniuc, B.4    Bhatia, G.5    Pollack, S.6
  • 24
    • 84922537760 scopus 로고    scopus 로고
    • Leveraging population admixture to characterize the heritability of complex traits
    • 25383972
    • Zaitlen N., Pasaniuc B., Sankararaman S., Bhatia G., Zhang J., Gusev A., et al. (2014). Leveraging population admixture to characterize the heritability of complex traits. Nature Genetics, 46(12), 1356–1362. doi: 10.1038/ng.3139 25383972
    • (2014) Nature Genetics , vol.46 , Issue.12 , pp. 1356-1362
    • Zaitlen, N.1    Pasaniuc, B.2    Sankararaman, S.3    Bhatia, G.4    Zhang, J.5    Gusev, A.6
  • 26
    • 84859261092 scopus 로고    scopus 로고
    • Heritability and genetic correlations explained by common SNPs for metabolic syndrome traits
    • 22479213
    • Vattikuti S., Guo J., Chow C. C., (2012). Heritability and genetic correlations explained by common SNPs for metabolic syndrome traits. PLoS Genetics, 8(3), e1002637. doi: 10.1371/journal.pgen.1002637 22479213
    • (2012) PLoS Genetics , vol.8 , Issue.3 , pp. e1002637
    • Vattikuti, S.1    Guo, J.2    Chow, C.C.3
  • 27
    • 84944358132 scopus 로고    scopus 로고
    • Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
    • 26323059
    • Yang J., Bakshi A., Zhu Z., Hemani G., Vinkhuyzen A. A., Lee S. H., et al. (2015). Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index. Nature Genetics, 47(10), 1114–1120. doi: 10.1038/ng.3390 26323059
    • (2015) Nature Genetics , vol.47 , Issue.10 , pp. 1114-1120
    • Yang, J.1    Bakshi, A.2    Zhu, Z.3    Hemani, G.4    Vinkhuyzen, A.A.5    Lee, S.H.6
  • 28
    • 84885360262 scopus 로고    scopus 로고
    • Childhood socioeconomic status amplifies genetic effects on adult intelligence
    • 24002887
    • Bates T. C., Lewis G. J., Weiss A., (2013). Childhood socioeconomic status amplifies genetic effects on adult intelligence. Psychological Science, 24(10), 2111–2116. doi: 10.1177/0956797613488394 24002887
    • (2013) Psychological Science , vol.24 , Issue.10 , pp. 2111-2116
    • Bates, T.C.1    Lewis, G.J.2    Weiss, A.3
  • 29
    • 84856480950 scopus 로고    scopus 로고
    • Socioeconomic status (SES) and children's intelligence (IQ): In a UK-representative sample SES moderates the environmental, not genetic, effect on IQ
    • 22312423
    • Hanscombe K. B., Trzaskowski M., Haworth C. M., Davis O. S., Dale P. S., Plomin R., (2012). Socioeconomic status (SES) and children's intelligence (IQ): In a UK-representative sample SES moderates the environmental, not genetic, effect on IQ. PLoS One, 7(2), e30320. doi: 10.1371/journal.pone.0030320 22312423
    • (2012) PLoS One , vol.7 , Issue.2 , pp. e30320
    • Hanscombe, K.B.1    Trzaskowski, M.2    Haworth, C.M.3    Davis, O.S.4    Dale, P.S.5    Plomin, R.6
  • 30
    • 85017330967 scopus 로고    scopus 로고
    • Replication of a gene–environment interaction via multimodel inference: additive-genetic variance in Adolescents’ General Cognitive Ability Increases with Family-of-Origin Socioeconomic Status
    • 25539975
    • Kirkpatrick R. M., McGue M., Iacono W. G., (2015). Replication of a gene–environment interaction via multimodel inference: additive-genetic variance in Adolescents’ General Cognitive Ability Increases with Family-of-Origin Socioeconomic Status. Behavior Genetics, 45(2), 200–214. doi: 10.1007/s10519-014-9698-y 25539975
    • (2015) Behavior Genetics , vol.45 , Issue.2 , pp. 200-214
    • Kirkpatrick, R.M.1    McGue, M.2    Iacono, W.G.3
  • 31
    • 84957951489 scopus 로고    scopus 로고
    • The Scarr-Rowe interaction in complete seven-year WISC data from the Louisville twin study: Preliminary report
    • 26497158
    • Turkheimer E., Beam C. E., Davis D. W., (2015). The Scarr-Rowe interaction in complete seven-year WISC data from the Louisville twin study: Preliminary report. Behavior Genetics, 45(6), 635–639. doi: 10.1007/s10519-015-9760-4 26497158
    • (2015) Behavior Genetics , vol.45 , Issue.6 , pp. 635-639
    • Turkheimer, E.1    Beam, C.E.2    Davis, D.W.3
  • 32
    • 77958499255 scopus 로고    scopus 로고
    • The heritability of general cognitive ability increases linearly from childhood to young adulthood
    • 19488046
    • Haworth C. M., Wright M. J., Luciano M., Martin N. G., De Geus E. J. C., Van Beijsterveldt C. E. M., et al. (2010). The heritability of general cognitive ability increases linearly from childhood to young adulthood. Molecular psychiatry, 15(11), 1112–1120. doi: 10.1038/mp.2009.55 19488046
    • (2010) Molecular psychiatry , vol.15 , Issue.11 , pp. 1112-1120
    • Haworth, C.M.1    Wright, M.J.2    Luciano, M.3    Martin, N.G.4    De Geus, E.J.C.5    Van Beijsterveldt, C.E.M.6
  • 33
    • 70350585040 scopus 로고    scopus 로고
    • Dramatic increase in heritability of cognitive development from early to middle childhood: An 8-year longitudinal study of 8,700 pairs of twins
    • 19732386
    • Davis O. S., Haworth C. M., Plomin R., (2009). Dramatic increase in heritability of cognitive development from early to middle childhood: An 8-year longitudinal study of 8,700 pairs of twins. Psychological Science, 20(10), 1301–1308. doi: 10.1111/j.1467-9280.2009.02433.x 19732386
    • (2009) Psychological Science , vol.20 , Issue.10 , pp. 1301-1308
    • Davis, O.S.1    Haworth, C.M.2    Plomin, R.3
  • 34
    • 84958056096 scopus 로고    scopus 로고
    • Large cross-national differences in gene × socioeconomic status interaction on intelligence
    • ., 0956797615612727
    • Tucker-Drob E. M., Bates T. C., (2015). Large cross-national differences in gene × socioeconomic status interaction on intelligence. Psychological science, 0956797615612727.
    • (2015) Psychological science
    • Tucker-Drob, E.M.1    Bates, T.C.2
  • 36
    • 55649114631 scopus 로고    scopus 로고
    • Sex-specific genetic effects influence variation in body composition
    • 18839131
    • Zillikens M. C., Yazdanpanah M., Pardo L. M., Rivadeneira F., Aulchenko Y. S., Oostra B. A., et al. (2008). Sex-specific genetic effects influence variation in body composition. Diabetologia, 51(12), 2233–2241. doi: 10.1007/s00125-008-1163-0 18839131
    • (2008) Diabetologia , vol.51 , Issue.12 , pp. 2233-2241
    • Zillikens, M.C.1    Yazdanpanah, M.2    Pardo, L.M.3    Rivadeneira, F.4    Aulchenko, Y.S.5    Oostra, B.A.6
  • 38
    • 0034121235 scopus 로고    scopus 로고
    • Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins
    • MacGregor A. J., Snieder H., Rigby A. S., Koskenvuo M., Kaprio J., Aho K., et al. (2000). Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins. Arthritis & Rheumatism, 43(1), 30.
    • (2000) Arthritis & Rheumatism , vol.43 , Issue.1 , pp. 30
    • MacGregor, A.J.1    Snieder, H.2    Rigby, A.S.3    Koskenvuo, M.4    Kaprio, J.5    Aho, K.6
  • 39
    • 84872239752 scopus 로고    scopus 로고
    • Age-stratified heritability estimation in the Framingham Heart Study families
    • Brown W. M., Beck S. R., Lange E. M., Davis C. C., Kay C. M., Langefeld C. D., et al. (2003). Age-stratified heritability estimation in the Framingham Heart Study families. BMC Genetics, 4(1), 1.
    • (2003) BMC Genetics , vol.4 , Issue.1 , pp. 1
    • Brown, W.M.1    Beck, S.R.2    Lange, E.M.3    Davis, C.C.4    Kay, C.M.5    Langefeld, C.D.6
  • 40
    • 60049101443 scopus 로고    scopus 로고
    • Genetic influences on change in BMI from middle to old age: a 29-year follow-up study of twin sisters
    • 19067155
    • Ortega-Alonso A., Sipilä S., Kujala U. M., Kaprio J., Rantanen T., (2009). Genetic influences on change in BMI from middle to old age: a 29-year follow-up study of twin sisters. Behavior Genetics, 39(2), 154–164. doi: 10.1007/s10519-008-9245-9 19067155
    • (2009) Behavior Genetics , vol.39 , Issue.2 , pp. 154-164
    • Ortega-Alonso, A.1    Sipilä, S.2    Kujala, U.M.3    Kaprio, J.4    Rantanen, T.5
  • 41
    • 0942290488 scopus 로고    scopus 로고
    • Twin study of genetic and environmental influences on adult body size, shape, and composition
    • 14610529
    • Schousboe K., Visscher P. M., Erbas B., Kyvik K. O., Hopper J. L., Henriksen J. E., et al. (2004). Twin study of genetic and environmental influences on adult body size, shape, and composition. International Journal of Obesity, 28(1), 39–48. doi: 10.1038/sj.ijo.0802524 14610529
    • (2004) International Journal of Obesity , vol.28 , Issue.1 , pp. 39-48
    • Schousboe, K.1    Visscher, P.M.2    Erbas, B.3    Kyvik, K.O.4    Hopper, J.L.5    Henriksen, J.E.6
  • 42
    • 58149303021 scopus 로고    scopus 로고
    • Increasing heritability of BMI and stronger associations with the FTO gene over childhood
    • 18846049
    • Haworth C., Carnell S., Meaburn E. L., Davis O. S., Plomin R., Wardle J., (2008). Increasing heritability of BMI and stronger associations with the FTO gene over childhood. Obesity, 16(12), 2663–2668. doi: 10.1038/oby.2008.434 18846049
    • (2008) Obesity , vol.16 , Issue.12 , pp. 2663-2668
    • Haworth, C.1    Carnell, S.2    Meaburn, E.L.3    Davis, O.S.4    Plomin, R.5    Wardle, J.6
  • 43
    • 84885861142 scopus 로고    scopus 로고
    • Variation in the heritability of body mass index based on diverse twin studies: a systematic review
    • 23980914
    • Min J., Chiu D. T., Wang Y., (2013). Variation in the heritability of body mass index based on diverse twin studies: a systematic review. Obesity Reviews, 14(11), 871–882. doi: 10.1111/obr.12065 23980914
    • (2013) Obesity Reviews , vol.14 , Issue.11 , pp. 871-882
    • Min, J.1    Chiu, D.T.2    Wang, Y.3
  • 44
    • 0025953819 scopus 로고
    • Heritability of ventilatory function in smoking and nonsmoking New Mexico Hispanics
    • 1928947
    • Coultas D. B., Hanis C. L., Howard C. A., Skipper B. J., Samet J. M., (1991). Heritability of ventilatory function in smoking and nonsmoking New Mexico Hispanics. American Review of Respiratory Disease, 144(4), 770–775. doi: 10.1164/ajrccm/144.4.770 1928947
    • (1991) American Review of Respiratory Disease , vol.144 , Issue.4 , pp. 770-775
    • Coultas, D.B.1    Hanis, C.L.2    Howard, C.A.3    Skipper, B.J.4    Samet, J.M.5
  • 46
  • 47
    • 84888137548 scopus 로고    scopus 로고
    • Heritability analyses show visit-to-visit blood pressure variability reflects different pathological phenotypes in younger and older adults: evidence from UK twins
    • 24029873
    • Menni C., Mangino M., Zhang F., Clement G., Snieder H., Padmanabhan S., et al. (2013). Heritability analyses show visit-to-visit blood pressure variability reflects different pathological phenotypes in younger and older adults: evidence from UK twins. Journal of Hypertension, 31(12), 2356–2361. doi: 10.1097/HJH.0b013e32836523c1 24029873
    • (2013) Journal of Hypertension , vol.31 , Issue.12 , pp. 2356-2361
    • Menni, C.1    Mangino, M.2    Zhang, F.3    Clement, G.4    Snieder, H.5    Padmanabhan, S.6
  • 48
    • 84940437553 scopus 로고    scopus 로고
    • Genetic influence on age at first birth of female twins born in the UK, 1919–68
    • 26234944
    • Tropf F. C., Barban N., Mills M. C., Snieder H., Mandemakers J. J., (2015). Genetic influence on age at first birth of female twins born in the UK, 1919–68. Population studies, 69(2), 129–145. doi: 10.1080/00324728.2015.1056823 26234944
    • (2015) Population studies , vol.69 , Issue.2 , pp. 129-145
    • Tropf, F.C.1    Barban, N.2    Mills, M.C.3    Snieder, H.4    Mandemakers, J.J.5
  • 49
    • 0035001426 scopus 로고    scopus 로고
    • The impact of genetic and environmental influences on blood pressure variance across age-groups
    • 11403347
    • Vinck W. J., Fagard R. H., Loos R., Vlietinck R., (2001). The impact of genetic and environmental influences on blood pressure variance across age-groups. Journal of Hypertension, 19(6), 1007–1013. 11403347
    • (2001) Journal of Hypertension , vol.19 , Issue.6 , pp. 1007-1013
    • Vinck, W.J.1    Fagard, R.H.2    Loos, R.3    Vlietinck, R.4
  • 50
    • 84928595221 scopus 로고    scopus 로고
    • Genetic contribution to the variance of blood pressure and heart rate: A systematic review and meta-regression of twin studies
    • Wang B., Liao C., Zhou B., Cao W., Lv J., Yu C., et al. (2015). Genetic contribution to the variance of blood pressure and heart rate: A systematic review and meta-regression of twin studies. Twin Research and Human Genetics, 18(02), 158–170.
    • (2015) Twin Research and Human Genetics , vol.18 , Issue.2 , pp. 158-170
    • Wang, B.1    Liao, C.2    Zhou, B.3    Cao, W.4    Lv, J.5    Yu, C.6
  • 53
    • 84977660577 scopus 로고    scopus 로고
    • Cognitive test scores in UK Biobank: data reduction in 480,416 participants and longitudinal stability in 20,346 participants
    • 27110937
    • Lyall D. M., Cullen B., Allerhand M., Smith D. J., Mackay D., Evans J., et al. (2016). Cognitive test scores in UK Biobank: data reduction in 480,416 participants and longitudinal stability in 20,346 participants. PloS one, 11(4), e0154222. doi: 10.1371/journal.pone.0154222 27110937
    • (2016) PloS one , vol.11 , Issue.4 , pp. e0154222
    • Lyall, D.M.1    Cullen, B.2    Allerhand, M.3    Smith, D.J.4    Mackay, D.5    Evans, J.6
  • 54
    • 84988442262 scopus 로고    scopus 로고
    • Characteristics of rheumatoid arthritis and its association with major comorbid conditions: cross-sectional study of 502 649 UK Biobank participants
    • 27403335
    • Siebert S., Lyall D. M., Mackay D. F., Porter D., McInnes I. B., Sattar N., et al. (2016). Characteristics of rheumatoid arthritis and its association with major comorbid conditions: cross-sectional study of 502 649 UK Biobank participants. RMD open, 2(1), e000267. doi: 10.1136/rmdopen-2016-000267 27403335
    • (2016) RMD open , vol.2 , Issue.1 , pp. e000267
    • Siebert, S.1    Lyall, D.M.2    Mackay, D.F.3    Porter, D.4    McInnes, I.B.5    Sattar, N.6
  • 55
    • 84961290792 scopus 로고    scopus 로고
    • Validation of electronic health record phenotyping of bipolar disorder cases and controls
    • 25827034
    • Castro V. M., Minnier J., Murphy S. N., Kohane I., Churchill S. E., Gainer V., et al. (2015). Validation of electronic health record phenotyping of bipolar disorder cases and controls. American Journal of Psychiatry, 172(4), 363–372. doi: 10.1176/appi.ajp.2014.14030423 25827034
    • (2015) American Journal of Psychiatry , vol.172 , Issue.4 , pp. 363-372
    • Castro, V.M.1    Minnier, J.2    Murphy, S.N.3    Kohane, I.4    Churchill, S.E.5    Gainer, V.6
  • 57
    • 84930651751 scopus 로고    scopus 로고
    • Development of phenotype algorithms using electronic medical records and incorporating natural language processing
    • 25911572
    • Liao K. P., Cai T., Savova G. K., Murphy S. N., Karlson E. W., Ananthakrishnan A. N., et al. (2015). Development of phenotype algorithms using electronic medical records and incorporating natural language processing. BMJ, 350, h1885. doi: 10.1136/bmj.h1885 25911572
    • (2015) BMJ , vol.350 , pp. h1885
    • Liao, K.P.1    Cai, T.2    Savova, G.K.3    Murphy, S.N.4    Karlson, E.W.5    Ananthakrishnan, A.N.6
  • 58
    • 82655165845 scopus 로고    scopus 로고
    • Using electronic medical records to enable large-scale studies in psychiatry: treatment resistant depression as a model
    • 21682950
    • Perlis R. H., Iosifescu D. V., Castro V. M., Murphy S. N., Gainer V. S., Minnier J., et al. (2012). Using electronic medical records to enable large-scale studies in psychiatry: treatment resistant depression as a model. Psychological Medicine, 42(1), 41–50. doi: 10.1017/S0033291711000997 21682950
    • (2012) Psychological Medicine , vol.42 , Issue.1 , pp. 41-50
    • Perlis, R.H.1    Iosifescu, D.V.2    Castro, V.M.3    Murphy, S.N.4    Gainer, V.S.5    Minnier, J.6
  • 59
    • 84870919039 scopus 로고    scopus 로고
    • Improved heritability estimation from genome-wide SNPs
    • 23217325
    • Speed D., Hemani G., Johnson M. R., Balding D. J., (2012). Improved heritability estimation from genome-wide SNPs. The American Journal of Human Genetics, 91(6), 1011–1021. doi: 10.1016/j.ajhg.2012.10.010 23217325
    • (2012) The American Journal of Human Genetics , vol.91 , Issue.6 , pp. 1011-1021
    • Speed, D.1    Hemani, G.2    Johnson, M.R.3    Balding, D.J.4
  • 61
    • 79957588287 scopus 로고    scopus 로고
    • Genome partitioning of genetic variation for complex traits using common SNPs
    • 21552263
    • Yang J., Manolio T. A., Pasquale L. R., Boerwinkle E., Caporaso N., Cunningham J. M., et al. (2011). Genome partitioning of genetic variation for complex traits using common SNPs. Nature genetics, 43(6), 519–525. doi: 10.1038/ng.823 21552263
    • (2011) Nature genetics , vol.43 , Issue.6 , pp. 519-525
    • Yang, J.1    Manolio, T.A.2    Pasquale, L.R.3    Boerwinkle, E.4    Caporaso, N.5    Cunningham, J.M.6
  • 62
    • 84997409303 scopus 로고    scopus 로고
    • Mega-analysis of 31,396 individuals from 6 countries uncovers strong gene-environment interaction for human fertility
    • 049163
    • Tropf, F. C., Verweij, R. M., van der Most, P. J., Stulp, G., Bakshi, A., Briley, D. A., et al. (2016). Mega-analysis of 31,396 individuals from 6 countries uncovers strong gene-environment interaction for human fertility. BioRxiv, 049163.
    • (2016) BioRxiv
    • Tropf, F.C.1    Verweij, R.M.2    van der Most, P.J.3    Stulp, G.4    Bakshi, A.5    Briley, D.A.6
  • 63
    • 84959227093 scopus 로고    scopus 로고
    • Genome-wide genetic homogeneity between sexes and populations for human height and body mass index
    • . ., ddv443
    • Yang J., Bakshi A., Zhu Z., Hemani G., Vinkhuyzen A. A., Nolte I. M., et al. (2015). Genome-wide genetic homogeneity between sexes and populations for human height and body mass index. Human molecular genetics, ddv443.
    • (2015) Human molecular genetics
    • Yang, J.1    Bakshi, A.2    Zhu, Z.3    Hemani, G.4    Vinkhuyzen, A.A.5    Nolte, I.M.6
  • 64
    • 84927126442 scopus 로고    scopus 로고
    • Relatedness in the post-genomic era: is it still useful?
    • 25404112
    • Speed D., Balding D. J., (2015). Relatedness in the post-genomic era: is it still useful?Nature Reviews Genetics, 16(1), 33–44. doi: 10.1038/nrg3821 25404112
    • (2015) Nature Reviews Genetics , vol.16 , Issue.1 , pp. 33-44
    • Speed, D.1    Balding, D.J.2
  • 66
    • 84982976085 scopus 로고    scopus 로고
    • GCTA-GREML accounts for linkage disequilibrium when estimating genetic variance from genome-wide SNPs
    • Yang J., Lee S. H., Wray N. R., Goddard M. E., Visscher P. M., (2016). GCTA-GREML accounts for linkage disequilibrium when estimating genetic variance from genome-wide SNPs. Proceedings of the National Academy of Sciences, 113(32), E4579–E4580.
    • (2016) Proceedings of the National Academy of Sciences , vol.113 , Issue.32 , pp. E4579-E4580
    • Yang, J.1    Lee, S.H.2    Wray, N.R.3    Goddard, M.E.4    Visscher, P.M.5
  • 68
  • 70
    • 84995478515 scopus 로고    scopus 로고
    • Multidimensional heritability analysis of neuroanatomical shape
    • 27845344
    • Ge T., Reuter M., Winkler A. M., Holmes A. J., Lee P. H., Tirrell L. S., et al. (2016). Multidimensional heritability analysis of neuroanatomical shape. Nature Communications, 7, 13291. doi: 10.1038/ncomms13291 27845344
    • (2016) Nature Communications , vol.7 , pp. 13291
    • Ge, T.1    Reuter, M.2    Winkler, A.M.3    Holmes, A.J.4    Lee, P.H.5    Tirrell, L.S.6
  • 72
    • 77955058518 scopus 로고
    • The inheritance of liability to certain diseases, estimated from the incidence among relatives
    • Falconer D. S., (1965). The inheritance of liability to certain diseases, estimated from the incidence among relatives. Annals of Human Genetics, 29(1), 51–76.
    • (1965) Annals of Human Genetics , vol.29 , Issue.1 , pp. 51-76
    • Falconer, D.S.1
  • 73
    • 84885837543 scopus 로고
    • Mathematical contributions to the theory of evolution VII—On the application of certain formulae in the theory of correlation to the inheritance of characters not capable of quantitative measurement
    • Pearson K., Lee A., (1901). Mathematical contributions to the theory of evolution VII—On the application of certain formulae in the theory of correlation to the inheritance of characters not capable of quantitative measurement. Proceedings of the Royal Society of London, 66(424–433), 324–327.
    • (1901) Proceedings of the Royal Society of London , vol.66 , Issue.424-433 , pp. 324-327
    • Pearson, K.1    Lee, A.2
  • 74
    • 0001118328 scopus 로고
    • Heritability of threshold characters
    • 17247344
    • Dempster E. R., Lerner I. M., (1950). Heritability of threshold characters. Genetics, 35(2), 212. 17247344
    • (1950) Genetics , vol.35 , Issue.2 , pp. 212
    • Dempster, E.R.1    Lerner, I.M.2
  • 75
    • 84899513456 scopus 로고    scopus 로고
    • Fast principal component analysis of large-scale genome-wide data
    • 24718290
    • Abraham G., Inouye M., (2014). Fast principal component analysis of large-scale genome-wide data. PLoS One, 9(4), e93766. doi: 10.1371/journal.pone.0093766 24718290
    • (2014) PLoS One , vol.9 , Issue.4 , pp. e93766
    • Abraham, G.1    Inouye, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.