-
1
-
-
84885022205
-
Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene
-
Sosnay PR, Siklosi KR, Van Goor F, Kaniecki K, Yu H, Sharma N, Ramalho AS, Amaral MD, Dorfman R, Zielenski J, et al. Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene. Nat Genet 2013; 45:1160-1167.
-
(2013)
Nat Genet
, vol.45
, pp. 1160-1167
-
-
Sosnay, P.R.1
Siklosi, K.R.2
Van Goor, F.3
Kaniecki, K.4
Yu, H.5
Sharma, N.6
Ramalho, A.S.7
Amaral, M.D.8
Dorfman, R.9
Zielenski, J.10
-
2
-
-
84942312604
-
Targeted therapies to improve CFTR function in cystic fibrosis
-
Brodlie M, Haq IJ, Roberts K, Elborn JS. Targeted therapies to improve CFTR function in cystic fibrosis. Genome Med 2015;7:101.
-
(2015)
Genome Med
, vol.7
, pp. 101
-
-
Brodlie, M.1
Haq, I.J.2
Roberts, K.3
Elborn, J.S.4
-
3
-
-
84956613592
-
From CFTR biology toward combinatorial pharmacotherapy: Expanded classification of cystic fibrosis mutations
-
Veit G, Avramescu RG, Chiang AN, Houck SA, Cai Z, Peters KW, Hong JS, Pollard HB, Guggino WB, Balch WE, et al. From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations. Mol Biol Cell 2016;27: 424-433.
-
(2016)
Mol Biol Cell
, vol.27
, pp. 424-433
-
-
Veit, G.1
Avramescu, R.G.2
Chiang, A.N.3
Houck, S.A.4
Cai, Z.5
Peters, K.W.6
Hong, J.S.7
Pollard, H.B.8
Guggino, W.B.9
Balch, W.E.10
-
4
-
-
78549279173
-
Effect of VX-770 in persons with cystic fibrosis and the G551D-CFTR mutation
-
Accurso FJ, Rowe SM, Clancy JP, BoyleMP, Dunitz JM, Durie PR, Sagel SD, Hornick DB, Konstan MW, Donaldson SH, et al. Effect of VX-770 in persons with cystic fibrosis and the G551D-CFTR mutation. N Engl J Med 2010;363:1991-2003.
-
(2010)
N Engl J Med
, vol.363
, pp. 1991-2003
-
-
Accurso, F.J.1
Rowe, S.M.2
Clancy, J.P.3
Boyle, M.P.4
Dunitz, J.M.5
Durie, P.R.6
Sagel, S.D.7
Hornick, D.B.8
Konstan, M.W.9
Donaldson, S.H.10
-
5
-
-
84937035647
-
Lumacaftor-ivacaftor in patients with cystic fibrosis homozygous for Phe508del CFTR
-
Wainwright CE, Elborn JS, Ramsey BW, Marigowda G, Huang X, Cipolli M, Colombo C, Davies JC, De Boeck K, Flume PA, et al.; TRAFFIC Study Group; TRANSPORT Study Group. Lumacaftor-ivacaftor in patients with cystic fibrosis homozygous for Phe508del CFTR. N Engl J Med 2015;373:220-231.
-
(2015)
N Engl J Med
, vol.373
, pp. 220-231
-
-
Wainwright, C.E.1
Elborn, J.S.2
Ramsey, B.W.3
Marigowda, G.4
Huang, X.5
Cipolli, M.6
Colombo, C.7
Davies, J.C.8
De Boeck, K.9
Flume, P.A.10
-
6
-
-
77954975403
-
Human keratinocytes are efficiently immortalized by a Rho kinase inhibitor
-
Chapman S, Liu X, Meyers C, Schlegel R, McBride AA. Human keratinocytes are efficiently immortalized by a Rho kinase inhibitor. J Clin Invest 2010;120:2619-2626.
-
(2010)
J Clin Invest
, vol.120
, pp. 2619-2626
-
-
Chapman, S.1
Liu, X.2
Meyers, C.3
Schlegel, R.4
McBride, A.A.5
-
7
-
-
84862908154
-
ROCK inhibitor and feeder cells induce the conditional reprogramming of epithelial cells
-
Liu X, Ory V, Chapman S, Yuan H, Albanese C, Kallakury B, Timofeeva OA, Nealon C, Dakic A, Simic V, et al. ROCK inhibitor and feeder cells induce the conditional reprogramming of epithelial cells. Am J Pathol 2012;180:599-607.
-
(2012)
Am J Pathol
, vol.180
, pp. 599-607
-
-
Liu, X.1
Ory, V.2
Chapman, S.3
Yuan, H.4
Albanese, C.5
Kallakury, B.6
Timofeeva, O.A.7
Nealon, C.8
Dakic, A.9
Simic, V.10
-
8
-
-
84870599083
-
Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells
-
Suprynowicz FA, Upadhyay G, Krawczyk E, Kramer SC, Hebert JD, Liu X, Yuan H, Cheluvaraju C, Clapp PW, Boucher RC Jr, et al. Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells. Proc Natl Acad Sci USA 2012;109: 20035-20040.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 20035-20040
-
-
Suprynowicz, F.A.1
Upadhyay, G.2
Krawczyk, E.3
Kramer, S.C.4
Hebert, J.D.5
Liu, X.6
Yuan, H.7
Cheluvaraju, C.8
Clapp, P.W.9
Boucher, R.C.10
-
9
-
-
84883473051
-
Rho-associated protein kinase inhibition enhances airway epithelial Basal-cell proliferation and lentivirus transduction
-
Horani A, Nath A, Wasserman MG, Huang T, Brody SL. Rho-associated protein kinase inhibition enhances airway epithelial Basal-cell proliferation and lentivirus transduction. Am J Respir Cell Mol Biol 2013;49:341-347.
-
(2013)
Am J Respir Cell Mol Biol
, vol.49
, pp. 341-347
-
-
Horani, A.1
Nath, A.2
Wasserman, M.G.3
Huang, T.4
Brody, S.L.5
-
10
-
-
84896534982
-
Mutations in RSPH1 cause primary ciliary dyskinesia with a unique clinical and ciliary phenotype
-
Knowles MR, Ostrowski LE, Leigh MW, Sears PR, Davis SD, Wolf WE, Hazucha MJ, Carson JL, Olivier KN, Sagel SD, et al. Mutations in RSPH1 cause primary ciliary dyskinesia with a unique clinical and ciliary phenotype. Am J Respir Crit Care Med 2014;189:707-717.
-
(2014)
Am J Respir Crit Care Med
, vol.189
, pp. 707-717
-
-
Knowles, M.R.1
Ostrowski, L.E.2
Leigh, M.W.3
Sears, P.R.4
Davis, S.D.5
Wolf, W.E.6
Hazucha, M.J.7
Carson, J.L.8
Olivier, K.N.9
Sagel, S.D.10
-
11
-
-
84943449480
-
CRISPR-Cas9-mediated gene knockout in primary human airway epithelial cells reveals a proinflammatory role for MUC18
-
Chu HW, Rios C, Huang C, Wesolowska-Andersen A, Burchard EG, O'Connor BP, Fingerlin TE, Nichols D, Reynolds SD, Seibold MA. CRISPR-Cas9-mediated gene knockout in primary human airway epithelial cells reveals a proinflammatory role for MUC18. Gene Ther 2015;22:822-829.
-
(2015)
Gene Ther
, vol.22
, pp. 822-829
-
-
Chu, H.W.1
Rios, C.2
Huang, C.3
Wesolowska-Andersen, A.4
Burchard, E.G.5
O'Connor, B.P.6
Fingerlin, T.E.7
Nichols, D.8
Reynolds, S.D.9
Seibold, M.A.10
-
12
-
-
84988938994
-
Rapid expansion of human epithelial stem cells suitable for airway tissue engineering
-
Butler CR, Hynds RE, Gowers KH, Lee DdoH, Brown JM, Crowley C, Teixeira VH, Smith CM, Urbani L, Hamilton NJ, et al. Rapid expansion of human epithelial stem cells suitable for airway tissue engineering. Am J Respir Crit Care Med 2016;194:156-168.
-
(2016)
Am J Respir Crit Care Med
, vol.194
, pp. 156-168
-
-
Butler, C.R.1
Hynds, R.E.2
Gowers, K.H.3
Lee, D.H.4
Brown, J.M.5
Crowley, C.6
Teixeira, V.H.7
Smith, C.M.8
Urbani, L.9
Hamilton, N.J.10
-
13
-
-
84870502577
-
Human nasal and tracheo-bronchial respiratory epithelial cell culture
-
Fulcher ML, Randell SH. Human nasal and tracheo-bronchial respiratory epithelial cell culture. Methods Mol Biol 2013;945: 109-121.
-
(2013)
Methods Mol Biol
, vol.945
, pp. 109-121
-
-
Fulcher, M.L.1
Randell, S.H.2
-
14
-
-
80052327898
-
Use of primary cultures of human bronchial epithelial cells isolated from cystic fibrosis patients for the pre-clinical testing of CFTR modulators
-
Neuberger T, Burton B, Clark H, Van Goor F. Use of primary cultures of human bronchial epithelial cells isolated from cystic fibrosis patients for the pre-clinical testing of CFTR modulators. Methods Mol Biol 2011;741:39-54.
-
(2011)
Methods Mol Biol
, vol.741
, pp. 39-54
-
-
Neuberger, T.1
Burton, B.2
Clark, H.3
Van Goor, F.4
-
15
-
-
16644381108
-
Welldifferentiated human airway epithelial cell cultures
-
Fulcher ML, Gabriel S, Burns KA, Yankaskas JR, Randell SH. Welldifferentiated human airway epithelial cell cultures. Methods Mol Med 2005;107:183-206.
-
(2005)
Methods Mol Med
, vol.107
, pp. 183-206
-
-
Fulcher, M.L.1
Gabriel, S.2
Burns, K.A.3
Yankaskas, J.R.4
Randell, S.H.5
-
16
-
-
84988946309
-
Airway progenitor clone formation is enhanced by Y-27632- dependent changes in the transcriptome
-
Reynolds SD, Rios C, Wesolowska-Andersen A, Zhuang Y, Pinter M, Happoldt C, Hill CL, Lallier SW, Cosgrove GP, Solomon GM, et al. Airway progenitor clone formation is enhanced by Y-27632- dependent changes in the transcriptome. Am J Respir Cell Mol Biol 2016;55:323-336.
-
(2016)
Am J Respir Cell Mol Biol
, vol.55
, pp. 323-336
-
-
Reynolds, S.D.1
Rios, C.2
Wesolowska-Andersen, A.3
Zhuang, Y.4
Pinter, M.5
Happoldt, C.6
Hill, C.L.7
Lallier, S.W.8
Cosgrove, G.P.9
Solomon, G.M.10
-
17
-
-
84990922590
-
Dual SMAD signaling inhibition enables long-term expansion of diverse epithelial basal cells
-
Mou H, Vinarsky V, Tata PR, Brazauskas K, Choi SH, Crooke AK, Zhang B, Solomon GM, Turner B, Bihler H, et al. Dual SMAD signaling inhibition enables long-term expansion of diverse epithelial basal cells. Cell Stem Cell 2016;19:217-231.
-
(2016)
Cell Stem Cell
, vol.19
, pp. 217-231
-
-
Mou, H.1
Vinarsky, V.2
Tata, P.R.3
Brazauskas, K.4
Choi, S.H.5
Crooke, A.K.6
Zhang, B.7
Solomon, G.M.8
Turner, B.9
Bihler, H.10
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