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Volumn 7, Issue 1, 2017, Pages

In-Vivo Efficacy of Chloroquine to Clear Asymptomatic Infections in Mozambican Adults: A Randomized, Placebo-controlled Trial with Implications for Elimination Strategies

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE;

EID: 85018276748     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-01365-4     Document Type: Article
Times cited : (21)

References (41)
  • 1
    • 84857089282 scopus 로고    scopus 로고
    • Pfcrt haplotypes and the evolutionary history of chloroquine-resistant Plasmodium falciparum
    • Awasthi, G., Satya Prasad, G. B. & Das, A. Pfcrt haplotypes and the evolutionary history of chloroquine-resistant Plasmodium falciparum. Memorias do Instituto Oswaldo Cruz 107, 129-134, doi: 10.1590/S0074-02762012000100018 (2012).
    • (2012) Memorias Do Instituto Oswaldo Cruz , vol.107 , pp. 129-134
    • Awasthi, G.1    Satya Prasad, G.B.2    Das, A.3
  • 2
    • 0014907959 scopus 로고
    • Resistance of P. Falciparum to chloroquine in Africa: True or false
    • Bruce-Chwatt, L. J. Resistance of P. falciparum to chloroquine in Africa: True or false? Trans R Soc Trop Med Hyg 64, 776-784, doi: 10.1016/0035-9203(70)90022-2 (1970).
    • (1970) Trans R Soc Trop Med Hyg , vol.64 , pp. 776-784
    • Bruce-Chwatt, L.J.1
  • 3
    • 0013842098 scopus 로고
    • Chloroquine-resistant falciparum malaria in Thailand
    • Harinasuta, T., Suntharasamai, P. & Viravan, C. Chloroquine-resistant falciparum malaria in Thailand. Lancet 2, 657-660 (1965).
    • (1965) Lancet , vol.2 , pp. 657-660
    • Harinasuta, T.1    Suntharasamai, P.2    Viravan, C.3
  • 5
    • 68049117184 scopus 로고    scopus 로고
    • Impaired fitness of drug-resistant malaria parasites: Evidence and implication on drug-deployment policies
    • Babiker, H. A., Hastings, I. M. & Swedberg, G. Impaired fitness of drug-resistant malaria parasites: Evidence and implication on drug-deployment policies. Expert review of anti-infective therapy 7, 581-593, doi: 10.1586/eri.09.29 (2009).
    • (2009) Expert Review of Anti-infective Therapy , vol.7 , pp. 581-593
    • Babiker, H.A.1    Hastings, I.M.2    Swedberg, G.3
  • 6
    • 0035945682 scopus 로고    scopus 로고
    • A molecular marker for chloroquine-resistant falciparum malaria
    • Djimde, A. et al. A molecular marker for chloroquine-resistant falciparum malaria. N Engl J Med 344, 257-263, doi: 10.1056/NEJM200101253440403 (2001).
    • (2001) N Engl J Med , vol.344 , pp. 257-263
    • Djimde, A.1
  • 7
    • 0038239207 scopus 로고    scopus 로고
    • Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi
    • doi:JID30387 [pii] 10.1086/375419
    • Kublin, J. G. et al. Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi. J Infect Dis 187, 1870-1875, doi: 10.1086/jid.2003.187.issue-12, doi:JID30387 [pii]10.1086/375419 (2003).
    • (2003) J Infect Dis , vol.187 , pp. 1870-1875
    • Kublin, J.G.1
  • 8
    • 0042808413 scopus 로고    scopus 로고
    • Recovery of chloroquine sensitivity and low prevalence of the Plasmodium falciparum chloroquine resistance transporter gene mutation K76T following the discontinuance of chloroquine use in Malawi
    • Mita, T. et al. Recovery of chloroquine sensitivity and low prevalence of the Plasmodium falciparum chloroquine resistance transporter gene mutation K76T following the discontinuance of chloroquine use in Malawi. The American journal of tropical medicine and hygiene 68, 413-415 (2003).
    • (2003) The American Journal of Tropical Medicine and Hygiene , vol.68 , pp. 413-415
    • Mita, T.1
  • 9
    • 0034995901 scopus 로고    scopus 로고
    • Therapeutic efficacy of sulphadoxine/pyrimethamine and susceptibility in vitro of P. Falciparum isolates to sulphadoxine-pyremethamine and other antimalarial drugs in Malawian children
    • doi:tmi735 [pii]
    • Takechi, M. et al. Therapeutic efficacy of sulphadoxine/pyrimethamine and susceptibility in vitro of P. falciparum isolates to sulphadoxine-pyremethamine and other antimalarial drugs in Malawian children. Trop Med Int Health 6, 429-434, doi: 10.1046/j.1365-3156.2001.00735.x, doi:tmi735 [pii] (2001).
    • (2001) Trop Med Int Health , vol.6 , pp. 429-434
    • Takechi, M.1
  • 10
    • 84906936219 scopus 로고    scopus 로고
    • The return of widespread chloroquine-sensitive Plasmodium falciparum to Malawi
    • doi:jiu216 [pii]10.1093/infdis/jiu216
    • Frosch, A. E. et al. The return of widespread chloroquine-sensitive Plasmodium falciparum to Malawi. J Infect Dis, doi:jiu216 [pii]10.1093/infdis/jiu216 (2014).
    • (2014) J Infect Dis
    • Frosch, A.E.1
  • 11
    • 85002252528 scopus 로고    scopus 로고
    • The return of chloroquine-susceptible Plasmodium falciparum malaria in Zambia
    • Mwanza, S. et al. The return of chloroquine-susceptible Plasmodium falciparum malaria in Zambia. Malaria journal 15, 584, doi: 10.1186/s12936-016-1637-3 (2016).
    • (2016) Malaria Journal , vol.15 , pp. 584
    • Mwanza, S.1
  • 12
    • 84887334412 scopus 로고    scopus 로고
    • Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania
    • doi:1475-2875-12-415[pii]10.1186/1475-2875-12-415
    • Mohammed, A. et al. Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania. Malaria journal 12, 415, doi: 10.1186/1475-2875-12-415, doi:1475-2875-12-415[pii]10.1186/1475-2875-12-415 (2013).
    • (2013) Malaria Journal , vol.12 , pp. 415
    • Mohammed, A.1
  • 13
    • 67650685545 scopus 로고    scopus 로고
    • Chloroquine resistance before and after its withdrawal in Kenya
    • doi:1475-2875-8-106 [pii]10.1186/1475-2875-8-106
    • Mwai, L. et al. Chloroquine resistance before and after its withdrawal in Kenya. Malaria journal 8, 106, doi: 10.1186/1475-2875-8-106, doi:1475-2875-8-106 [pii]10.1186/1475-2875-8-106 (2013).
    • (2013) Malaria Journal , vol.8 , pp. 106
    • Mwai, L.1
  • 14
    • 33750730913 scopus 로고    scopus 로고
    • Return of chloroquine antimalarial efficacy in Malawi
    • doi:355/19/1959 [pii]10.1056/NEJMoa062032
    • Laufer, M. K. et al. Return of chloroquine antimalarial efficacy in Malawi. N Engl J Med 355, 1959-1966, doi: 10.1056/NEJMoa062032, doi:355/19/1959 [pii]10.1056/NEJMoa062032 (2006).
    • (2006) N Engl J Med , vol.355 , pp. 1959-1966
    • Laufer, M.K.1
  • 15
    • 84865095149 scopus 로고    scopus 로고
    • A longitudinal trial comparing chloroquine as monotherapy or in combination with artesunate, azithromycin or atovaquone-proguanil to treat malaria
    • Laufer, M. K. et al. A longitudinal trial comparing chloroquine as monotherapy or in combination with artesunate, azithromycin or atovaquone-proguanil to treat malaria. PloS one 7, e42284, doi: 10.1371/journal.pone.0042284 (2012).
    • (2012) PloS One , vol.7 , pp. e42284
    • Laufer, M.K.1
  • 16
    • 0035341841 scopus 로고    scopus 로고
    • Prevalence of the K76T mutation in the putative Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene and its relation to chloroquine resistance in Mozambique
    • doi:JID001261 [pii] 10.1086/319856
    • Mayor, A. G. et al. Prevalence of the K76T mutation in the putative Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene and its relation to chloroquine resistance in Mozambique. J Infect Dis 183, 1413-1416, doi: 10.1086/jid.2001.183.issue-9, doi:JID001261 [pii]10.1086/319856 (2001).
    • (2001) J Infect Dis , vol.183 , pp. 1413-1416
    • Mayor, A.G.1
  • 17
    • 80054692859 scopus 로고    scopus 로고
    • Five years of antimalarial resistance marker surveillance in Gaza Province, Mozambique, following artemisinin-based combination therapy roll out
    • 0025992PONE-D-11-14300 [pii]
    • Raman, J. et al. Five years of antimalarial resistance marker surveillance in Gaza Province, Mozambique, following artemisinin-based combination therapy roll out. PLoS One 6, e25992, doi: 10.1371/journal.pone, 0025992PONE-D-11-14300 [pii] (2011).
    • (2011) PLoS One , vol.6 , pp. e25992
    • Raman, J.1
  • 18
    • 84875513163 scopus 로고    scopus 로고
    • Rapid selection of Plasmodium falciparum chloroquine resistance transporter gene and multidrug resistance gene-1 haplotypes associated with past chloroquine and present artemether-lumefantrine use in Inhambane District, southern Mozambique
    • Thomsen, T. T. et al. Rapid selection of Plasmodium falciparum chloroquine resistance transporter gene and multidrug resistance gene-1 haplotypes associated with past chloroquine and present artemether-lumefantrine use in Inhambane District, southern Mozambique. The American journal of tropical medicine and hygiene 88, 536-541, doi: 10.4269/ajtmh.12-0525 (2013).
    • (2013) The American Journal of Tropical Medicine and Hygiene , vol.88 , pp. 536-541
    • Thomsen, T.T.1
  • 19
    • 10744232839 scopus 로고    scopus 로고
    • Efficacy of chloroquine, amodiaquine, sulphadoxine-pyrimethamine and combination therapy with artesunate in Mozambican children with non-complicated malaria
    • Abacassamo, F. et al. Efficacy of chloroquine, amodiaquine, sulphadoxine-pyrimethamine and combination therapy with artesunate in Mozambican children with non-complicated malaria. Trop Med Int Health 9, 200-208, doi: 10.1046/j.1365-3156.2003.01182.x (2004).
    • (2004) Trop Med Int Health , vol.9 , pp. 200-208
    • Abacassamo, F.1
  • 20
    • 0030858470 scopus 로고    scopus 로고
    • Assessment of the pharmacodynamic properties of antimalarial drugs in vivo
    • White, N. J. Assessment of the pharmacodynamic properties of antimalarial drugs in vivo. Antimicrobial agents and chemotherapy 41, 1413-1422 (1997).
    • (1997) Antimicrobial Agents and Chemotherapy , vol.41 , pp. 1413-1422
    • White, N.J.1
  • 21
    • 84984781456 scopus 로고    scopus 로고
    • A prospective cohort study to assess the micro-epidemiology of Plasmodium falciparum clinical malaria in Ilha Josina Machel (Manhica, Mozambique)
    • Galatas, B. et al. A prospective cohort study to assess the micro-epidemiology of Plasmodium falciparum clinical malaria in Ilha Josina Machel (Manhica, Mozambique). Malaria journal 15, 444, doi: 10.1186/s12936-016-1496-y (2016).
    • (2016) Malaria Journal , vol.15 , pp. 444
    • Galatas, B.1
  • 23
    • 0035208248 scopus 로고    scopus 로고
    • Comparison of methods for the rapid laboratory assessment of children with malaria
    • Planche, T. et al. Comparison of methods for the rapid laboratory assessment of children with malaria. Am J Trop Med Hyg 65, 599-602 (2001).
    • (2001) Am J Trop Med Hyg , vol.65 , pp. 599-602
    • Planche, T.1
  • 24
    • 60149107804 scopus 로고    scopus 로고
    • Sub-microscopic infections and long-term recrudescence of Plasmodium falciparum in Mozambican pregnant women
    • Mayor, A. et al. Sub-microscopic infections and long-term recrudescence of Plasmodium falciparum in Mozambican pregnant women. Malaria journal 8, 9, doi: 10.1186/1475-2875-8-9 (2009).
    • (2009) Malaria Journal , vol.8 , pp. 9
    • Mayor, A.1
  • 25
    • 84901651079 scopus 로고    scopus 로고
    • A quality control program within a clinical trial Consortium for PCR protocols to detect Plasmodium species
    • Taylor, S. M. et al. A quality control program within a clinical trial Consortium for PCR protocols to detect Plasmodium species. Journal of clinical microbiology 52, 2144-2149, doi: 10.1128/jcm.00565-14 (2014).
    • (2014) Journal of Clinical Microbiology , vol.52 , pp. 2144-2149
    • Taylor, S.M.1
  • 28
    • 70350552698 scopus 로고    scopus 로고
    • World Health Organization Available at accessed 25/02/2014). (WHO
    • World Health Organization. Methods for surveillance of antimalarial drug efficacy. Available at http://www.who.int/malaria/publications/atoz/9789241597531/en/(accessed 25/02/2014). (WHO, 2009).
    • (2009) Methods for Surveillance of Antimalarial Drug Efficacy
  • 29
    • 79954627480 scopus 로고    scopus 로고
    • The distribution of Plasmodium falciparum infection durations
    • Bretscher, M. T. et al. The distribution of Plasmodium falciparum infection durations. Epidemics 3, 109-118, doi: 10.1016/j.epidem.2011.03.002 (2011).
    • (2011) Epidemics , vol.3 , pp. 109-118
    • Bretscher, M.T.1
  • 30
    • 84876902157 scopus 로고    scopus 로고
    • Mathematical models of within-host and transmission dynamics to determine effects of malaria interventions in a variety of transmission settings
    • Eckhoff, P. Mathematical models of within-host and transmission dynamics to determine effects of malaria interventions in a variety of transmission settings. Am J Trop Med Hyg 88, 817-827, doi: 10.4269/ajtmh.12-0007 (2013).
    • (2013) Am J Trop Med Hyg , vol.88 , pp. 817-827
    • Eckhoff, P.1
  • 31
    • 84866518208 scopus 로고    scopus 로고
    • The dynamics of natural Plasmodium falciparum infections
    • Felger, I. et al. The dynamics of natural Plasmodium falciparum infections. PloS one 7, e45542, doi: 10.1371/journal.pone.0045542 (2012).
    • (2012) PloS One , vol.7 , pp. e45542
    • Felger, I.1
  • 32
    • 84978935340 scopus 로고    scopus 로고
    • World Health Organization
    • World Health Organization. Eliminating malaria (2016).
    • (2016) Eliminating Malaria
  • 33
    • 84950113740 scopus 로고    scopus 로고
    • Malaria parasites in the asymptomatic: Looking for the hay in the haystack
    • Galatas, B., Bassat, Q. & Mayor, A. Malaria Parasites in the Asymptomatic: Looking for the Hay in the Haystack. Trends in parasitology 32, 296-308, doi: 10.1016/j.pt.2015.11.015 (2016).
    • (2016) Trends in Parasitology , vol.32 , pp. 296-308
    • Galatas, B.1    Bassat, Q.2    Mayor, A.3
  • 34
    • 80053173631 scopus 로고    scopus 로고
    • The parasite clearance curve
    • White, N. J. The parasite clearance curve. Malaria journal 10, 278, doi: 10.1186/1475-2875-10-278 (2011).
    • (2011) Malaria Journal , vol.10 , pp. 278
    • White, N.J.1
  • 36
    • 84890450738 scopus 로고    scopus 로고
    • Assessment of pfcrt 72-76 haplotypes eight years after chloroquine withdrawal in Kinshasa, Democratic Republic of Congo
    • Mvumbi, D. M. et al. Assessment of pfcrt 72-76 haplotypes eight years after chloroquine withdrawal in Kinshasa, Democratic Republic of Congo. Malaria journal 12, 459, doi: 10.1186/1475-2875-12-459 (2013).
    • (2013) Malaria Journal , vol.12 , pp. 459
    • Mvumbi, D.M.1
  • 37
    • 0036786291 scopus 로고    scopus 로고
    • Origin and dissemination of Plasmodium falciparum drug-resistance mutations in South America
    • doi:JID020423 [pii] 10.1086/342946
    • Cortese, J. F., Caraballo, A., Contreras, C. E. & Plowe, C. V. Origin and dissemination of Plasmodium falciparum drug-resistance mutations in South America. J Infect Dis 186, 999-1006, doi: 10.1086/jid.2002.186.issue-7, doi:JID020423 [pii] 10.1086/342946 (2002).
    • (2002) J Infect Dis , vol.186 , pp. 999-1006
    • Cortese, J.F.1    Caraballo, A.2    Contreras, C.E.3    Plowe, C.V.4
  • 38
    • 0035877239 scopus 로고    scopus 로고
    • Analysis of the PfCRT K76T mutation in Plasmodium falciparum isolates from the Amazon region of Brazil
    • doi:JID010159[pii] 10.1086/320739
    • Vieira, P. P., das Gracas Alecrim, M., da Silva, L. H., Gonzalez-Jimenez, I. & Zalis, M. G. Analysis of the PfCRT K76T mutation in Plasmodium falciparum isolates from the Amazon region of Brazil. J Infect Dis 183, 1832-1833, doi: 10.1086/jid.2001.183.issue-12, doi:JID010159[pii] 10.1086/320739 (2001).
    • (2001) J Infect Dis , vol.183 , pp. 1832-1833
    • Vieira, P.P.1    Das Gracas Alecrim, M.2    Da Silva, L.H.3    Gonzalez-Jimenez, I.4    Zalis, M.G.5
  • 41
    • 40049110830 scopus 로고    scopus 로고
    • Artemisinin-based combination treatment of falciparum malaria
    • Nosten, F. & White, N. J. Artemisinin-based combination treatment of falciparum malaria. Am J Trop Med Hyg 77, 181-192 (2007).
    • (2007) Am J Trop Med Hyg , vol.77 , pp. 181-192
    • Nosten, F.1    White, N.J.2


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