Inhibition and Degradation of Amyloid Beta (Aβ40) Fibrillation by Designed Small Peptide: A Combined Spectroscopy, Microscopy, and Cell Toxicity Study

ACS Chemical Neuroscience

Volumn 8, Issue 4, 2017, Pages 718-722

  Ghosh, Anirban ^a   Pradhan, Nibedita ^b   Bera, Swapna ^a   Datta, Aritreyee ^a   Krishnamoorthy, Janarthanan ^c   Jana, Nikhil R ^b   Bhunia, Anirban ^a  

^a BOSE INSTITUTE   (India)

^b DEPARTMENT OF MATERIALS SCIENCE   (India)

^c SRI RAMACHANDRA UNIVERSITY   (India)

Author keywords

Alzheimer's disease; amyloid beta (A ); fibril disintegration; peptide; STD NMR; toxicity inhibitor

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; NF 11; PEPTIDOMIMETIC AGENT; TRYPTOPHAN; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; NF11 PEPTIDE; OLIGOPEPTIDE; PEPTIDE FRAGMENT;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANISOTROPY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DISSOCIATION CONSTANT; DISSOLUTION; FLUORESCENCE MICROSCOPY; HETERONUCLEAR MULTIPLE QUANTUM COHERENCE; HYDROPHOBICITY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTON NUCLEAR MAGNETIC RESONANCE; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; CHEMISTRY; DRUG EFFECTS; HUMAN; METABOLISM; NERVE CELL; PROTEIN AGGREGATION, PATHOLOGICAL;

AMYLOID BETA-PEPTIDES; ANIMALS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; NEURONS; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PROTEIN AGGREGATION, PATHOLOGICAL;

EID: 85018192829     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/acschemneuro.6b00349     Document Type: Article

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