Mitochondrial Chaperonin HSP60 Is the Apoptosis-Related Target for Myrtucommulone

Cell Chemical Biology

Volumn 24, Issue 5, 2017, Pages 614-623.e6

  Wiechmann, Katja ^a   Müller, Hans ^b   König, Stefanie ^a   Wielsch, Natalie ^c   Svatoš, Aleš ^c   Jauch, Johann ^b   Werz, Oliver ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c MAX PLANCK INSTITUTE FOR CHEMICAL ECOLOGY   (Germany)

Author keywords

apoptosis; heat shock protein 60; Lon protease like protein; mitochondria; myrtucommulone; target fishing

Indexed keywords

CHAPERONIN 60; CYTOCHROME C; MITOCHONDRIAL PROTEIN; MYRTUCOMMULONE; PHLOROGLUCINOL DERIVATIVE; UNCLASSIFIED DRUG; MYRTUCOMMULONE A; PHLOROGLUCINOL; PROTEIN AGGREGATE;

APOPTOSIS; ARTICLE; CHEMICAL STRUCTURE; HL-60 CELL LINE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; PROTEIN TARGETING; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; HEAT SHOCK RESPONSE; HUMAN; METABOLISM; MOLECULARLY TARGETED THERAPY;

APOPTOSIS; CHAPERONIN 60; CYTOCHROMES C; DRUG DESIGN; HEAT-SHOCK RESPONSE; HL-60 CELLS; HUMANS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR TARGETED THERAPY; PHLOROGLUCINOL; PROTEIN AGGREGATES;

EID: 85018163531     PISSN: 24519456     EISSN: 24519448     Source Type: Journal    
DOI: 10.1016/j.chembiol.2017.04.008     Document Type: Article

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