Structure-activity relationships of epolactaene derivatives: Structural requirements for inhibition of Hsp60 chaperone activity

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 17, 2004, Pages 4425-4429

  Nagumo, Yoko ^a   Kakeya, Hideaki ^a   Yamaguchi, Junichiro ^b   Uno, Takao ^b   Shoji, Mitsuru ^b   Hayashi, Yujiro ^b   Osada, Hiroyuki ^a  

^a RIKEN   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Chaperone; Epolactaene; Heat shock protein 60

Indexed keywords

CHAPERONE; EPOLACTEANE; HEAT SHOCK PROTEIN 60; LACTAM DERIVATIVE; MICROBIAL PRODUCTS NOT CLASSIFIED ELSEWHERE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; DRUG BINDING; FUNGAL STRAIN; HUMAN; HUMAN CELL; NERVE FIBER GROWTH; NEUROBLASTOMA; PENICILLIUM; STRUCTURE ACTIVITY RELATION;

CELL SURVIVAL; CHAPERONIN 60; EPOXY COMPOUNDS; HUMANS; JURKAT CELLS; POLYENES; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP;

PENICILLIUM; PENICILLIUM SP.;

EID: 3843120076     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.06.054     Document Type: Article

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