Efficacy of psychotherapies for borderline personality disorder: A systematic review and meta-analysis

JAMA Psychiatry

Volumn 74, Issue 4, 2017, Pages 319-328

  Cristea, Ioana A ^a,b,c   Gentili, Claudio ^b   Cotet, Carmen D ^a   Palomba, Daniela ^b   Barbui, Corrado ^d   Cuijpers, Pim ^e  

^a BABE BOLYAI UNIVERSITY   (Romania)

^b UNIVERSITY OF PADOVA   (Italy)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF VERONA   (Italy)

^e UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOMUTILATION; BORDERLINE STATE; COGNITIVE BEHAVIORAL THERAPY; CONTROLLED STUDY; FOLLOW UP; HEALTH CARE UTILIZATION; HUMAN; MENTAL DISEASE; META ANALYSIS; PSYCHODYNAMIC PSYCHOTHERAPY; PSYCHOTHERAPY; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SUICIDE; SYSTEMATIC REVIEW; BEHAVIOR THERAPY; BORDERLINE PERSONALITY DISORDER; PSYCHOLOGY; SELF-INJURIOUS BEHAVIOR; TREATMENT OUTCOME;

BEHAVIOR THERAPY; BORDERLINE PERSONALITY DISORDER; HUMANS; PSYCHOTHERAPY; PSYCHOTHERAPY, PSYCHODYNAMIC; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SELF-INJURIOUS BEHAVIOR; SUICIDE; TREATMENT OUTCOME;

EID: 85017644100     PISSN: 2168622X     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamapsychiatry.2016.4287     Document Type: Review

References (61)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Arlington, VA: American Psychiatric Association; 2013.
2. Oldham JM. Borderline personality disorder and suicidality. Am J Psychiatry. 2006;163(1):20-26.
3. American Psychiatric Association Practice Guidelines. Practice guideline for the treatment of patients with borderline personality disorder. Am J Psychiatry. 2001;158(10)(suppl):1-52.
4. Black DW, Blum N, Pfohl B, Hale N. Suicidal behavior in borderline personality disorder: prevalence, risk factors, prediction, and prevention. J Pers Disord. 2004;18(3):226-239.
5. Leichsenring F, Leibing E, Kruse J, New AS, Leweke F. Borderline personality disorder. Lancet. 2011;377(9759):74-84.
6. Gunderson JG. Borderline personality disorder: ontogeny of a diagnosis. Am J Psychiatry. 2009;166 (5):530-539.
7. Zanarini MC, Frankenburg FR, Hennen J, Silk KR. Mental health service utilization by borderline personality disorder patients and Axis II comparison subjects followed prospectively for 6 years. J Clin Psychiatry. 2004;65(1):28-36.
8. Zanarini MC, Frankenburg FR, Khera GS, Bleichmar J. Treatment histories of borderline inpatients. Compr Psychiatry. 2001;42(2):144-150.
9. Ten Have M, Verheul R, Kaasenbrood A, et al. Prevalence rates of borderline personality disorder symptoms:astudy based on the Netherlands Mental Health Survey and Incidence Study-2. BMC Psychiatry. 2016;16(1):249.
10. Skodol AE, Gunderson JG, McGlashan TH, et al. Functional impairment in patients with schizotypal, borderline, avoidant, or obsessive-compulsive personality disorder. Am J Psychiatry. 2002;159(2): 276-283.
11. Skodol AE, Pagano ME, Bender DS, et al. Stability of functional impairment in patients with schizotypal, borderline, avoidant, or obsessive-compulsive personality disorder over two years. Psychol Med. 2005;35(3):443-451.
12. Linehan MM. Cognitive-Behavioral Treatment of Borderline Personality Disorder. New York, NY: Guilford Press; 1993.
13. Beck AT, Freeman A. Cognitive Therapy of Personality Disorders. New York, NY: Guilford Press; 1990.
14. Bateman A, Fonagy P. Psychotherapy for Borderline Personality Disorder: Mentalisation Based Treatment. Oxford, England: Oxford University Press; 2004.
15. Clarkin JF, Yeomans FE, Kernberg OE. Psychotherapy for Borderline Personality. New York, NY: John Wiley& Sons; 1999.
16. Bateman A, Fonagy P. Randomized controlled trial of outpatient mentalization-based treatment versus structured clinical management for borderline personality disorder. Am J Psychiatry. 2009;166(12):1355-1364.
17. Davidson K, Norrie J, Tyrer P, et al. The effectiveness of cognitive behavior therapy for borderline personality disorder: results from the Borderline Personality Disorder Study of Cognitive Therapy (BOSCOT) trial. J Pers Disord. 2006;20(5): 450-465.
18. Doering S, Hörz S, Rentrop M, et al. Transference-focused psychotherapy v. treatment by community psychotherapists for borderline personality disorder: randomised controlled trial. Br J Psychiatry. 2010;196(5):389-395.
19. Linehan MM, Comtois KA, Murray AM, et al. Two-year randomized controlled trial and follow-up of dialectical behavior therapy vs therapy by experts for suicidal behaviors and borderline personality disorder. Arch Gen Psychiatry. 2006;63 (7):757-766.
20. Clarkin JF, Levy KN, Lenzenweger MF, Kernberg OF. Evaluating three treatments for borderline personality disorder: a multiwave study. Am J Psychiatry. 2007;164(6):922-928.
21. Giesen-Bloo J, van Dyck R, Spinhoven P, et al. Outpatient psychotherapy for borderline personality disorder: randomized trial of schema-focused therapy vs transference-focused psychotherapy. Arch Gen Psychiatry. 2006;63(6): 649-658.
22. Kliem S, Kröger C, Kosfelder J. Dialectical behavior therapy for borderline personality disorder: a meta-analysis using mixed-effects modeling. J Consult Clin Psychol. 2010;78(6):936-951.
23. Stoffers JM, Völlm BA, Rücker G, Timmer A, Huband N, Lieb K. Psychological therapies for people with borderline personality disorder. Cochrane Database Syst Rev. 2012;(8):CD005652.
24. Cox GR, Callahan P, Churchill R, et al. Psychological therapies versus antidepressant medication, alone and in combination for depression in children and adolescents. Cochrane Database Syst Rev. 2014;(11):CD008324.
25. Barth J, Munder T, Gerger H, et al. Comparative efficacy of seven psychotherapeutic interventions for patients with depression: a network meta-analysis. PLoS Med. 2013;10(5):e1001454. doi:10.1371/journal.pmed.1001454
26. Higgins JP, Altman DG, Gøtzsche PC, et al; Cochrane Bias Methods Group; Cochrane Statistical Methods Group. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928.
27. Hedges LV, Olkin I. Statistical Methods for Meta-Analysis. Orlando, FL: Academic Press; 1985.
28. Borenstein M, Hedges LV, Higgins JPT, Rothstein HR. Introduction to Meta-Analysis. Chichester, England: Wiley; 2009.
29. Kraemer HC, Kupfer DJ. Size of treatment effects and their importance to clinical research and practice. Biol Psychiatry. 2006;59(11):990-996.
30. Ioannidis JP, Patsopoulos NA, Evangelou E. Uncertainty in heterogeneity estimates in meta-analyses. BMJ. 2007;335(7626):914-916.
31. Orsini N, Bottai M, Higgins J, Buchan I. Heterogi: Stata module to quantify heterogeneity in a meta-analysis. http://econpapers.repec.org/software/bocbocode/s449201.htm. Published 2006. Accessed November 27, 2013.
32. Duval S, Tweedie R. Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics. 2000;56(2):455-463.
33. Kamalabadi MJ, Ahmadi SA, Etemadi O, Fatehizadeh M, Bahrami F, Firoozabadi A. A study of the effect of couple dialectical behavioral therapy on symptoms and quality of marital relationships and mental health of Iranian borderline personality couples: a controlled trial. Interdiscip J Contemp Res Bus. 2012;3(9):1480-1487.
34. Linehan MM, Schmidt H III, Dimeff LA, Craft JC, Kanter J, Comtois KA. Dialectical behavior therapy for patients with borderline personality disorder and drug-dependence. Am J Addict. 1999;8(4):279-292.
35. Linehan MM, Dimeff LA, Reynolds SK, et al. Dialectical behavior therapy versus comprehensive validation therapy plus 12-step for the treatment of opioid dependent women meeting criteria for borderline personality disorder. Drug Alcohol Depend. 2002;67(1):13-26.
36. Munroe-Blum H, Marziali E. A controlled trial of short-term group treatment for borderline personality disorder. J Pers Disord. 1995;9(3):190-198. doi:10.1521/pedi.1995.9.3.190
37. Bateman A, Fonagy P. Effectiveness of partial hospitalization in the treatment of borderline personality disorder: a randomized controlled trial. Am J Psychiatry. 1999;156(10):1563-1569.
38. Linehan MM, Armstrong HE, Suarez A, Allmon D, Heard HL. Cognitive-behavioral treatment of chronically parasuicidal borderline patients. Arch Gen Psychiatry. 1991;48(12):1060-1064.
39. Verheul R, Van Den Bosch LM, Koeter MW, De Ridder MA, Stijnen T, Van Den Brink W. Dialectical behaviour therapy for women with borderline personality disorder: 12-month, randomised clinical trial in the Netherlands. Br J Psychiatry. 2003;182: 135-140.
40. McMain SF, Links PS, Gnam WH, et al. A randomized trial of dialectical behavior therapy versus general psychiatric management for borderline personality disorder. Am J Psychiatry. 2009;166(12):1365-1374.
41. Bos EH, van Wel EB, Appelo MT, Verbraak MJ. A randomized controlled trial of a Dutch version of systems training for emotional predictability and problem solving for borderline personality disorder. J Nerv Ment Dis. 2010;198(4):299-304.
42. Koons CR, Robins CJ, Tweed JL, et al. Efficacy of dialectical behavior therapy in women veterans with borderline personality disorder. Behav Ther. 2001;32(2):371-390. doi:10.1016/S0005-7894(01) 80009-5
43. Amianto F, Ferrero A, Pierò A, et al. Supervised team management, with orwithout structured psychotherapy, in heavy users of a mental health service with borderline personality disorder: a two-year follow-up preliminary randomized study. BMC Psychiatry. 2011;11:181.
44. Blum N, St John D, Pfohl B, et al. Systems Training for Emotional Predictability and Problem Solving (STEPPS) for outpatients with borderline personality disorder: a randomized controlled trial and 1-year follow-up. Am J Psychiatry. 2008;165(4): 468-478.
45. Carter GL, Willcox CH, Lewin TJ, Conrad AM, Bendit N. Hunter DBT project: randomized controlled trial of dialectical behaviour therapy in women with borderline personality disorder. Aust N Z J Psychiatry. 2010;44(2):162-173.
46. Cottraux J, Note ID, Boutitie F, et al. Cognitive therapy versus Rogerian supportive therapy in borderline personality disorder: two-year follow-up of a controlled pilot study. Psychother Psychosom. 2009;78(5):307-316.
47. Farrell JM, Shaw IA, Webber MA. A schema-focused approach to group psychotherapy for outpatients with borderline personality disorder: a randomized controlled trial. J Behav Ther Exp Psychiatry. 2009;40(2):317-328.
48. Gratz KL, Gunderson JG. Preliminary data on an acceptance-based emotion regulation group intervention for deliberate self-harm among women with borderline personality disorder. Behav Ther. 2006;37(1):25-35.
49. Gratz KL, Tull MT, Levy R. Randomized controlled trial and uncontrolled 9-month follow-up of an adjunctive emotion regulation group therapy for deliberate self-harm among women with borderline personality disorder. Psychol Med. 2014; 44(10):2099-2112.
50. Gregory RJ, Chlebowski S, Kang D, et al. A controlled trial of psychodynamic psychotherapy for co-occurring borderline personality disorder and alcohol use disorder. Psychotherapy (Chic). 2008; 45(1):28-41.
51. Jørgensen CR, Freund C, Bøye R, Jordet H, Andersen D, Kjølbye M. Outcome of mentalization-based and supportive psychotherapy in patients with borderline personality disorder: a randomized trial. Acta Psychiatr Scand. 2013;127 (4):305-317.
52. Kramer U, Kolly S, Berthoud L, et al. Effects of motive-oriented therapeutic relationship in a ten-session general psychiatric treatment of borderline personality disorder: a randomized controlled trial. Psychother Psychosom. 2014;83(3): 176-186.
53. Leppänen V, Hakko H, Sintonen H, Lindeman S. Comparing effectiveness of treatments for borderline personality disorder in communal mental health care: the Oulu BPD Study. Community Ment Health J. 2016;52(2):216-227.
54. Pascual JC, Palomares N, Ibáñez Á, et al. Efficacy of cognitive rehabilitation on psychosocial functioning in borderline personality disorder: a randomized controlled trial. BMC Psychiatry. 2015;15:255.
55. Priebe S, Bhatti N, Barnicot K, et al. Effectiveness and cost-effectiveness of dialectical behaviour therapy for self-harming patients with personality disorder: a pragmatic randomised controlled trial. Psychother Psychosom. 2012;81(6): 356-365.
56. Reneses B, Galián M, Serrano R, et al. A new time limited psychotherapy for BPD: preliminary results of a randomized and controlled trial. Actas Esp Psiquiatr. 2013;41(3):139-148.
57. Soler J, Pascual JC, Tiana T, et al. Dialectical behaviour therapy skills training compared to standard group therapy in borderline personality disorder: a 3-month randomised controlled clinical trial. Behav Res Ther. 2009;47(5):353-358.
58. Turner RM. Naturalistic evaluation of dialectical behavior therapy-oriented treatment for borderline personality disorder. Cogn Behav Pract. 2000;7(4): 413-419.
59. Weinberg I, Gunderson JG, Hennen J, Cutter CJ Jr. Manual assisted cognitive treatment for deliberate self-harm in borderline personality disorder patients. J Pers Disord. 2006;20(5):482-492.
60. Barnicot K, Katsakou C, Marougka S, Priebe S. Treatment completion in psychotherapy for borderline personality disorder: a systematic review and meta-analysis. Acta Psychiatr Scand. 2011;123 (5):327-338.
61. Higgins JPT, Green S, eds. Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1.0. http://training.cochrane.org/handbook. Updated March 2011. Accessed November 2016.