-
1
-
-
19144368324
-
Cytochrome P450 2C8: substrates, inhibitors, pharmacogenetics, and clinical relevance
-
Totah, R.A., Rettie, A.E., Cytochrome P450 2C8: substrates, inhibitors, pharmacogenetics, and clinical relevance. Clin Pharmacol Ther 77 (2005), 341–352.
-
(2005)
Clin Pharmacol Ther
, vol.77
, pp. 341-352
-
-
Totah, R.A.1
Rettie, A.E.2
-
2
-
-
70149110672
-
Polymorphism of human cytochrome P450 enzymes and its clinical impact
-
Zhou, S.F., Liu, J.P., Chowbay, B., Polymorphism of human cytochrome P450 enzymes and its clinical impact. Drug Metab Rev 41 (2009), 89–295.
-
(2009)
Drug Metab Rev
, vol.41
, pp. 89-295
-
-
Zhou, S.F.1
Liu, J.P.2
Chowbay, B.3
-
3
-
-
84956645530
-
Cytochrome P450 2C8*2 allele in Botswana: human genetic diversity and public health implications
-
Motshoge, T., Tawe, L., Muthoga, C.W., Allotey, J., Romano, R., Quaye, I., et al. Cytochrome P450 2C8*2 allele in Botswana: human genetic diversity and public health implications. Acta Trop 157 (2016), 54–58.
-
(2016)
Acta Trop
, vol.157
, pp. 54-58
-
-
Motshoge, T.1
Tawe, L.2
Muthoga, C.W.3
Allotey, J.4
Romano, R.5
Quaye, I.6
-
4
-
-
0034791777
-
Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid
-
Dai, D., Zeldin, D.C., Blaisdell, J.A., Chanas, B., Coulter, S.J., Ghanayem, B.I., et al. Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid. Pharmacogenetics 11 (2001), 597–607.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 597-607
-
-
Dai, D.1
Zeldin, D.C.2
Blaisdell, J.A.3
Chanas, B.4
Coulter, S.J.5
Ghanayem, B.I.6
-
5
-
-
84943514846
-
Functional characterization of 12 allelic variants of CYP2C8 by assessment of paclitaxel 6α-hydroxylation and amodiaquine N-deethylation
-
Tsukada, C., Saito, T., Maekawa, M., Mano, N., Oda, A., Hirasawa, N., et al. Functional characterization of 12 allelic variants of CYP2C8 by assessment of paclitaxel 6α-hydroxylation and amodiaquine N-deethylation. Drug Metab Pharmacokinet 30 (2015), 366–373.
-
(2015)
Drug Metab Pharmacokinet
, vol.30
, pp. 366-373
-
-
Tsukada, C.1
Saito, T.2
Maekawa, M.3
Mano, N.4
Oda, A.5
Hirasawa, N.6
-
6
-
-
84863958746
-
Genetic polymorphisms of CYP2C8 in the Czech Republic
-
Pechandova, K., Buzkova, H., Matouskova, O., Perlik, F., Slanar, O., Genetic polymorphisms of CYP2C8 in the Czech Republic. Genet Test Mol Biomarkers 16 (2012), 812–816.
-
(2012)
Genet Test Mol Biomarkers
, vol.16
, pp. 812-816
-
-
Pechandova, K.1
Buzkova, H.2
Matouskova, O.3
Perlik, F.4
Slanar, O.5
-
7
-
-
84860195435
-
Distribution of human CYP2C8*2 allele in three different African populations
-
Paganotti, G.M., Gramolelli, S., Tabacchi, F., Russo, G., Modiano, D., Coluzzi, M., et al. Distribution of human CYP2C8*2 allele in three different African populations. Malar J, 11, 2012, 125.
-
(2012)
Malar J
, vol.11
, pp. 125
-
-
Paganotti, G.M.1
Gramolelli, S.2
Tabacchi, F.3
Russo, G.4
Modiano, D.5
Coluzzi, M.6
-
8
-
-
85020646883
-
Genetic polymorphisms of the drug-metabolizing enzyme cytochrome P450 3A5 in a Uyghur Chinese population
-
Chen, Z., Li, J., Chen, P., Wang, F., Zhang, N., Yang, M., et al. Genetic polymorphisms of the drug-metabolizing enzyme cytochrome P450 3A5 in a Uyghur Chinese population. Xenobiotica 7 (2016), 1–7.
-
(2016)
Xenobiotica
, vol.7
, pp. 1-7
-
-
Chen, Z.1
Li, J.2
Chen, P.3
Wang, F.4
Zhang, N.5
Yang, M.6
-
9
-
-
84875211310
-
Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation
-
Zanger, U.M., Schwab, M., Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation. Pharmacol Ther 138 (2013), 103–141.
-
(2013)
Pharmacol Ther
, vol.138
, pp. 103-141
-
-
Zanger, U.M.1
Schwab, M.2
-
10
-
-
66249116333
-
The genetic structure and history of Africans and African Americans
-
Tishkoff, S.A., Reed, F.A., Friedlaender, F.R., Ehret, C., Ranciaro, A., Froment, A., et al. The genetic structure and history of Africans and African Americans. Science 324 (2009), 1035–1044.
-
(2009)
Science
, vol.324
, pp. 1035-1044
-
-
Tishkoff, S.A.1
Reed, F.A.2
Friedlaender, F.R.3
Ehret, C.4
Ranciaro, A.5
Froment, A.6
-
11
-
-
0028914819
-
Taxol metabolism and disposition in cancer patients
-
Walle, T., Walle, U.K., Kumar, G.N., Bhalla, K.N., Taxol metabolism and disposition in cancer patients. Drug Metab Dispos 23 (1995), 506–512.
-
(1995)
Drug Metab Dispos
, vol.23
, pp. 506-512
-
-
Walle, T.1
Walle, U.K.2
Kumar, G.N.3
Bhalla, K.N.4
-
12
-
-
1842636202
-
Development and evaluation of a rapid and reliable method for cytochrome P450 2C8 genotyping
-
Weise, A., Grundler, S., Zaumsegel, D., Klotzek, M., Gröndahl, B., Forst, T., et al. Development and evaluation of a rapid and reliable method for cytochrome P450 2C8 genotyping. Clin Lab 50 (2004), 141–148.
-
(2004)
Clin Lab
, vol.50
, pp. 141-148
-
-
Weise, A.1
Grundler, S.2
Zaumsegel, D.3
Klotzek, M.4
Gröndahl, B.5
Forst, T.6
-
13
-
-
0038532388
-
Genetic polymorphisms of CYP2C8 in Japanese population
-
Nakajima, M., Fujiki, Y., Noda, K., Ohtsuka, H., Ohkuni, H., Kyo, S., et al. Genetic polymorphisms of CYP2C8 in Japanese population. Drug Metab Dispos 31 (2003), 687–690.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 687-690
-
-
Nakajima, M.1
Fujiki, Y.2
Noda, K.3
Ohtsuka, H.4
Ohkuni, H.5
Kyo, S.6
-
14
-
-
84920829535
-
Cytochrome P450 single nucleotide polymorphisms in an indigenous Tanzanian population: a concern about the metabolism of artemisinin-based combinations
-
420
-
Marwa, K.J., Schmidt, T., Sjögren, M., Minzi, O.M., Kamugisha, E., Swedberg, G., Cytochrome P450 single nucleotide polymorphisms in an indigenous Tanzanian population: a concern about the metabolism of artemisinin-based combinations. Malar J, 3, 2014 420.
-
(2014)
Malar J
, vol.3
-
-
Marwa, K.J.1
Schmidt, T.2
Sjögren, M.3
Minzi, O.M.4
Kamugisha, E.5
Swedberg, G.6
-
15
-
-
85020663399
-
-
The 1000 genome project. [Accessed 22.08.2016].
-
The 1000 genome project. http://www.1000genomes.org. [Accessed 22.08.2016].
-
-
-
-
16
-
-
80155194178
-
Human genetic variation is associated with Plasmodium falciparum drug-resistance
-
Paganotti, G.M., Gallo, B.C., Verra, F., Sirima, B.S., Nebié, I., Diarra, A., et al. Human genetic variation is associated with Plasmodium falciparum drug-resistance. J Infect Dis 204 (2011), 1772–1778.
-
(2011)
J Infect Dis
, vol.204
, pp. 1772-1778
-
-
Paganotti, G.M.1
Gallo, B.C.2
Verra, F.3
Sirima, B.S.4
Nebié, I.5
Diarra, A.6
-
17
-
-
84871579941
-
Evaluation of the relationship between sex, polymorphisms in CYP2C8 and CYP2C9, and pharmacokinetics of angiotensin receptor blockers
-
Cabaleiro, T., Román, M., Ochoa, D., Talegón, M., Prieto-Pérez, R., Wojnicz, A., et al. Evaluation of the relationship between sex, polymorphisms in CYP2C8 and CYP2C9, and pharmacokinetics of angiotensin receptor blockers. Drug Metab Dispos 41 (2013), 224–229.
-
(2013)
Drug Metab Dispos
, vol.41
, pp. 224-229
-
-
Cabaleiro, T.1
Román, M.2
Ochoa, D.3
Talegón, M.4
Prieto-Pérez, R.5
Wojnicz, A.6
-
18
-
-
84976451961
-
Chronic myeloid leukemia in nigerian patients: anemia is an independent predictor of overall survival
-
Oyekunle, A.A., Durosinmi, M.A., Bolarinwa, R.A., Owojuyigbe, T., Salawu, L., Akinola, N.O., Chronic myeloid leukemia in nigerian patients: anemia is an independent predictor of overall survival. Clin Med Insights Blood Disord 20 (2016), 9–13.
-
(2016)
Clin Med Insights Blood Disord
, vol.20
, pp. 9-13
-
-
Oyekunle, A.A.1
Durosinmi, M.A.2
Bolarinwa, R.A.3
Owojuyigbe, T.4
Salawu, L.5
Akinola, N.O.6
-
19
-
-
84871540169
-
Autoinhibition of CYP3A4 leads to important role of CYP2C8 in imatinib metabolism: variability in CYP2C8 activity may alter plasma concentrations and response
-
Filppula, A.M., Neuvonen, M., Laitila, J., Neuvonen, P.J., Backman, J.T., Autoinhibition of CYP3A4 leads to important role of CYP2C8 in imatinib metabolism: variability in CYP2C8 activity may alter plasma concentrations and response. Drug Metab Dispos 41 (2013), 50–59.
-
(2013)
Drug Metab Dispos
, vol.41
, pp. 50-59
-
-
Filppula, A.M.1
Neuvonen, M.2
Laitila, J.3
Neuvonen, P.J.4
Backman, J.T.5
-
20
-
-
84955128528
-
Role of cytochrome P450 2C8 in drug metabolism and interactions
-
Backman, J.T., Filppula, A.M., Niemi, M., Neuvonen, P.J., Role of cytochrome P450 2C8 in drug metabolism and interactions. Pharmacol Rev 68 (2016), 168–241.
-
(2016)
Pharmacol Rev
, vol.68
, pp. 168-241
-
-
Backman, J.T.1
Filppula, A.M.2
Niemi, M.3
Neuvonen, P.J.4
-
21
-
-
84947996823
-
The Absence of CYP3A5*3 is a protective factor to anticonvulsants hypersensitivity reactions: a case-control study in brazilian subjects
-
e0136141
-
Tanno, L.K., Kerr, D.S., dos Santos, B., Talib, L.L., Yamaguti, C., Rodrigues, H., et al. The Absence of CYP3A5*3 is a protective factor to anticonvulsants hypersensitivity reactions: a case-control study in brazilian subjects. PLoS One, 10, 2015 e0136141.
-
(2015)
PLoS One
, vol.10
-
-
Tanno, L.K.1
Kerr, D.S.2
dos Santos, B.3
Talib, L.L.4
Yamaguti, C.5
Rodrigues, H.6
-
22
-
-
84881477865
-
Androgen metabolism gene polymorphisms, associations with prostate cancer risk and pathological characteristics: a comparative analysis between south african and senegalese men
-
Fernandez, P., Zeigler-Johnson, C.M., Spangler, E., van der Merwe, A., Jalloh, M., Gueye, S.M., et al. Androgen metabolism gene polymorphisms, associations with prostate cancer risk and pathological characteristics: a comparative analysis between south african and senegalese men. Prostate Cancer, 2012, 2012, 798634.
-
(2012)
Prostate Cancer
, vol.2012
, pp. 798634
-
-
Fernandez, P.1
Zeigler-Johnson, C.M.2
Spangler, E.3
van der Merwe, A.4
Jalloh, M.5
Gueye, S.M.6
-
23
-
-
84876981068
-
Molecular diversity and population structure at the Cytochrome P450 3A5 gene in Africa
-
Bains, R.K., Kovacevic, M., Plaster, C.A., Tarekegn, A., Bekele, E., Bradman, N.N., et al. Molecular diversity and population structure at the Cytochrome P450 3A5 gene in Africa. BMC Genet, 14, 2013, 34.
-
(2013)
BMC Genet
, vol.14
, pp. 34
-
-
Bains, R.K.1
Kovacevic, M.2
Plaster, C.A.3
Tarekegn, A.4
Bekele, E.5
Bradman, N.N.6
-
24
-
-
0036381491
-
Allele and genotype frequencies of CYP2B6 and CYP3A5 in the Japanese population
-
Hiratsuka, M., Takekuma, Y., Endo, N., Narahara, K., Hamdy, S.I., Kishikawa, Y., et al. Allele and genotype frequencies of CYP2B6 and CYP3A5 in the Japanese population. Eur J Clin Pharmacol 58 (2002), 417–421.
-
(2002)
Eur J Clin Pharmacol
, vol.58
, pp. 417-421
-
-
Hiratsuka, M.1
Takekuma, Y.2
Endo, N.3
Narahara, K.4
Hamdy, S.I.5
Kishikawa, Y.6
-
25
-
-
84962869309
-
Prediction of tacrolimus metabolism and dosage requirements based on CYP3A4 phenotype and CYP3A5*3 genotype in Chinese renal transplant recipients
-
Luo, X., Zhu, L.J., Cai, N.F., Zheng, L.Y., Cheng, Z.N., Prediction of tacrolimus metabolism and dosage requirements based on CYP3A4 phenotype and CYP3A5*3 genotype in Chinese renal transplant recipients. Acta Pharmacol Sin 37 (2016), 555–560.
-
(2016)
Acta Pharmacol Sin
, vol.37
, pp. 555-560
-
-
Luo, X.1
Zhu, L.J.2
Cai, N.F.3
Zheng, L.Y.4
Cheng, Z.N.5
-
26
-
-
84957640649
-
CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma
-
Noll, E.M., Eisen, C., Stenzinger, A., Espinet, E., Muckenhuber, A., Klein, C., et al. CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma. Nat Med 22 (2016), 278–287.
-
(2016)
Nat Med
, vol.22
, pp. 278-287
-
-
Noll, E.M.1
Eisen, C.2
Stenzinger, A.3
Espinet, E.4
Muckenhuber, A.5
Klein, C.6
-
27
-
-
77952950824
-
Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans
-
Mukonzo, J.K., Waako, P., Ogwal-Okeng, J., Gustafsson, L.L., Aklillu, E., Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans. Ther Drug Monit 32 (2010), 346–352.
-
(2010)
Ther Drug Monit
, vol.32
, pp. 346-352
-
-
Mukonzo, J.K.1
Waako, P.2
Ogwal-Okeng, J.3
Gustafsson, L.L.4
Aklillu, E.5
-
28
-
-
84983203344
-
Influence of CYP3A5 genetic variation on everolimus maintenance dosing after cardiac transplantation
-
Lesche, D., Sigurdardottir, V., Setoud, R., Englberger, L., Fiedler, G.M., Largiadèr, C.R., et al. Influence of CYP3A5 genetic variation on everolimus maintenance dosing after cardiac transplantation. Clin Transpl 29 (2015), 1213–1220.
-
(2015)
Clin Transpl
, vol.29
, pp. 1213-1220
-
-
Lesche, D.1
Sigurdardottir, V.2
Setoud, R.3
Englberger, L.4
Fiedler, G.M.5
Largiadèr, C.R.6
-
29
-
-
84939832993
-
CYP3A5 mediates bioactivation and cytotoxicity of tetrandrine
-
Tian, Y., Shen, S., Jiang, Y., Shen, Q., Zeng, S., Zheng, J., CYP3A5 mediates bioactivation and cytotoxicity of tetrandrine. Arch Toxicol 90 (2016), 1737–1748.
-
(2016)
Arch Toxicol
, vol.90
, pp. 1737-1748
-
-
Tian, Y.1
Shen, S.2
Jiang, Y.3
Shen, Q.4
Zeng, S.5
Zheng, J.6
|