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Volumn 123, Issue 2, 2017, Pages 325-339

Lactic acid bacteria — promising vaccine vectors: possibilities, limitations, doubts

Author keywords

gut microflora; heterologous gene expression; lactic acid bacteria; oral administration; vaccine vectors

Indexed keywords

ANTIGENS; BACTERIA; GENE EXPRESSION; LABORATORIES; LACTIC ACID; PROTEINS; STRAIN;

EID: 85017368612     PISSN: 13645072     EISSN: 13652672     Source Type: Journal    
DOI: 10.1111/jam.13446     Document Type: Review
Times cited : (72)

References (91)
  • 1
    • 0031959148 scopus 로고    scopus 로고
    • Specific immunity induction at the mucosal level by viable Lactobacillus casei: a perspective for oral vaccine development
    • Alvarez, S., Gobbato, N., Bru, E., de Ruiz Holgado, A.P. and Perdigón, G. (1998) Specific immunity induction at the mucosal level by viable Lactobacillus casei: a perspective for oral vaccine development. Food Agric Immunol 10, 79–87.
    • (1998) Food Agric Immunol , vol.10 , pp. 79-87
    • Alvarez, S.1    Gobbato, N.2    Bru, E.3    de Ruiz Holgado, A.P.4    Perdigón, G.5
  • 2
    • 0003351156 scopus 로고
    • Effect of lactic microbes on superoxide anion generating ability of peritoneal macrophages and tissue histopathology of murines
    • Balasubramanya, N.N., Lokesh, B.R., Ramesh, H.P. and Krishnakantha, T.P. (1995) Effect of lactic microbes on superoxide anion generating ability of peritoneal macrophages and tissue histopathology of murines. Indian J Dairy Biosci 6, 28–33.
    • (1995) Indian J Dairy Biosci , vol.6 , pp. 28-33
    • Balasubramanya, N.N.1    Lokesh, B.R.2    Ramesh, H.P.3    Krishnakantha, T.P.4
  • 4
    • 0025787798 scopus 로고
    • Alpha-toxin of Staphylococcus aureus
    • Bhakdi, S. and Tranumjensen, J. (1991) Alpha-toxin of Staphylococcus aureus. Microbiol Rev 55, 733–751.
    • (1991) Microbiol Rev , vol.55 , pp. 733-751
    • Bhakdi, S.1    Tranumjensen, J.2
  • 5
    • 70349435397 scopus 로고    scopus 로고
    • Intra- and interspecies conjugal transfer of Tn916-like elements from Lactococcus lactis in vitro and in vivo
    • Boguslawska, J., Zycka-Krzesinska, J., Wilcks, A. and Bardowski, J. (2009) Intra- and interspecies conjugal transfer of Tn916-like elements from Lactococcus lactis in vitro and in vivo. Appl Environ Microbiol 75, 6352–6360.
    • (2009) Appl Environ Microbiol , vol.75 , pp. 6352-6360
    • Boguslawska, J.1    Zycka-Krzesinska, J.2    Wilcks, A.3    Bardowski, J.4
  • 6
    • 43649105546 scopus 로고    scopus 로고
    • Nasal immunization if mice with Lactobacillus casei expressing the pneumococcal surface protein A: induction of antibodies, complement deposition and partial protection against Streptococcus pneumoniae challenge on the mouse respiratory tract
    • Campos, I.B., Darriuex, M., Ferreira, D.M., Miyaji, E.N., Silva, D.A., Areas, A.P., Aires, K.A., Leite, L.C. et al. (2008) Nasal immunization if mice with Lactobacillus casei expressing the pneumococcal surface protein A: induction of antibodies, complement deposition and partial protection against Streptococcus pneumoniae challenge on the mouse respiratory tract. Microbes Infect 10, 481–488.
    • (2008) Microbes Infect , vol.10 , pp. 481-488
    • Campos, I.B.1    Darriuex, M.2    Ferreira, D.M.3    Miyaji, E.N.4    Silva, D.A.5    Areas, A.P.6    Aires, K.A.7    Leite, L.C.8
  • 7
    • 0029258924 scopus 로고
    • Development of a vaccine strategy against human and bovine schistosomiasis. Background and update
    • Capron, A., Riveau, G., Grzych, J.M., Boulanger, D., Capron, M. and Pierce, R. (1995) Development of a vaccine strategy against human and bovine schistosomiasis. Background and update. Mem Inst Oswaldo Cruz 90, 235–240.
    • (1995) Mem Inst Oswaldo Cruz , vol.90 , pp. 235-240
    • Capron, A.1    Riveau, G.2    Grzych, J.M.3    Boulanger, D.4    Capron, M.5    Pierce, R.6
  • 9
    • 14544291591 scopus 로고    scopus 로고
    • Oral administration of Lactobacillus casei CRL 431 increases immunity in bronchus and mammary glands
    • De Moreno de LeBlanc, A., Maldonado Galdeano, C., Chaves, S. and Perdigon, G. (2005) Oral administration of Lactobacillus casei CRL 431 increases immunity in bronchus and mammary glands. Eur J Inflamm 3, 23–28.
    • (2005) Eur J Inflamm , vol.3 , pp. 23-28
    • De Moreno de LeBlanc, A.1    Maldonado Galdeano, C.2    Chaves, S.3    Perdigon, G.4
  • 10
    • 0142152433 scopus 로고    scopus 로고
    • Innate CD4CD25 regulatory T cells are required for oral tolerance and inhibition of CD8 T cells mediating skin inflammation
    • Dubois, B., Chapat, L., Goubier, A., Papiernik, M., Nicolas, J.F. and Kaiserlian, D. (2003) Innate CD4CD25 regulatory T cells are required for oral tolerance and inhibition of CD8 T cells mediating skin inflammation. Blood 102, 3295–3301.
    • (2003) Blood , vol.102 , pp. 3295-3301
    • Dubois, B.1    Chapat, L.2    Goubier, A.3    Papiernik, M.4    Nicolas, J.F.5    Kaiserlian, D.6
  • 11
    • 0028898650 scopus 로고
    • Characterisation of genetic elements required for site-specific integration of Lactobacillus delbrueckii subsp. bulgaricus bacteriophage mv4 and construction of an integration proficient vector for Lactobacillus plantarum
    • Dupont, L., Boizet-Bonhoure, B., Coddeville, M., Auvray, F. and Ritzenthaler, P. (1995) Characterisation of genetic elements required for site-specific integration of Lactobacillus delbrueckii subsp. bulgaricus bacteriophage mv4 and construction of an integration proficient vector for Lactobacillus plantarum. J Bacteriol 177, 586–595.
    • (1995) J Bacteriol , vol.177 , pp. 586-595
    • Dupont, L.1    Boizet-Bonhoure, B.2    Coddeville, M.3    Auvray, F.4    Ritzenthaler, P.5
  • 12
    • 0025855140 scopus 로고
    • Demonstration of peptidoglycan-binding sites on lymphocytes and macrophages by photoaffinity cross-linking
    • Dziarski, R. (1991) Demonstration of peptidoglycan-binding sites on lymphocytes and macrophages by photoaffinity cross-linking. J Biol Chem 266, 4713–4718.
    • (1991) J Biol Chem , vol.266 , pp. 4713-4718
    • Dziarski, R.1
  • 14
    • 0023272674 scopus 로고
    • Immunisation of mice against tetanus toxin with fragments of tetanus toxin synthesised in Escherichia coli
    • Fairweather, N.F., Lyness, V.A. and Maskell, D.J. (1987) Immunisation of mice against tetanus toxin with fragments of tetanus toxin synthesised in Escherichia coli. Infect Immun 55, 2541–2545.
    • (1987) Infect Immun , vol.55 , pp. 2541-2545
    • Fairweather, N.F.1    Lyness, V.A.2    Maskell, D.J.3
  • 15
    • 33748605901 scopus 로고    scopus 로고
    • Systemic and mucosal immunity to respiratory sincitial virus induced by recombinant Streptococcus gordonii surface displaying a domain of viral glycoprotein G
    • Falcone, V., Mihm, D., Neumann-Haefelin, D., Costa, C., Nguyen, T., Pozzi, G. and Ricci, S. (2006) Systemic and mucosal immunity to respiratory sincitial virus induced by recombinant Streptococcus gordonii surface displaying a domain of viral glycoprotein G. FEMS Immunol Med Microbiol 48, 116–122.
    • (2006) FEMS Immunol Med Microbiol , vol.48 , pp. 116-122
    • Falcone, V.1    Mihm, D.2    Neumann-Haefelin, D.3    Costa, C.4    Nguyen, T.5    Pozzi, G.6    Ricci, S.7
  • 16
    • 84964322267 scopus 로고
    • Anticarcinogenic and immunological properties of dietary lactobacilli
    • Fernandes, C.F. and Shahani, K.M. (1990) Anticarcinogenic and immunological properties of dietary lactobacilli. J Food Prot 53, 704–710.
    • (1990) J Food Prot , vol.53 , pp. 704-710
    • Fernandes, C.F.1    Shahani, K.M.2
  • 17
    • 0027357826 scopus 로고
    • Biologically active peptides from milk proteins with emphasis on two examples concerning antithrombotic and immunomodulating activities
    • Fiat, A.M., Migliore-Samour, D., Jollès, P., Drouet, L., Sollier, C.B. and Caen, J. (1993) Biologically active peptides from milk proteins with emphasis on two examples concerning antithrombotic and immunomodulating activities. J Dairy Sci 76, 301–310.
    • (1993) J Dairy Sci , vol.76 , pp. 301-310
    • Fiat, A.M.1    Migliore-Samour, D.2    Jollès, P.3    Drouet, L.4    Sollier, C.B.5    Caen, J.6
  • 18
    • 0346775764 scopus 로고    scopus 로고
    • An introduction
    • In, ed., Fuller, R., pp, London, England, Chapman & Hall
    • Fuller, R. (1997) An introduction. In Probiotics 2: Applications and Practical Aspects ed. Fuller, R., pp 1–9. London, England: Chapman & Hall.
    • (1997) Probiotics 2: Applications and Practical Aspects , pp. 1-9
    • Fuller, R.1
  • 20
    • 0033987529 scopus 로고    scopus 로고
    • Use of GreenFluorescent protein to tag lactic acid bacterium strains under development as live vaccine vectors
    • Geoffroy, M.C., Guyard, C., Quatannens, B., Pavan, S., Lange, M. and Mercenier, A. (2000) Use of GreenFluorescent protein to tag lactic acid bacterium strains under development as live vaccine vectors. Appl Environ Microbiol 66, 383–391.
    • (2000) Appl Environ Microbiol , vol.66 , pp. 383-391
    • Geoffroy, M.C.1    Guyard, C.2    Quatannens, B.3    Pavan, S.4    Lange, M.5    Mercenier, A.6
  • 21
    • 0027996351 scopus 로고
    • Regulatory effects of bifidobacteria on the growth of other colonic bacteria
    • Gibson, G.R. and Wang, X. (1994) Regulatory effects of bifidobacteria on the growth of other colonic bacteria. J Appl Bacteriol 77, 412–420.
    • (1994) J Appl Bacteriol , vol.77 , pp. 412-420
    • Gibson, G.R.1    Wang, X.2
  • 23
    • 33846141477 scopus 로고    scopus 로고
    • Mucosal delivery of a pneumococcal vaccine using Lactococcus lactis affords protection against respiratory infection
    • Hanniffy, S.B., Carter, A.T., Hitchin, E. and Wells, J.M. (2007) Mucosal delivery of a pneumococcal vaccine using Lactococcus lactis affords protection against respiratory infection. J Infect Dis 195, 185–193.
    • (2007) J Infect Dis , vol.195 , pp. 185-193
    • Hanniffy, S.B.1    Carter, A.T.2    Hitchin, E.3    Wells, J.M.4
  • 24
  • 25
  • 26
    • 84865957800 scopus 로고    scopus 로고
    • Food-grade selection markers in lactic acid bacteria
    • He, S., Gong, F., Guo, Y. and Zhang, D. (2012) Food-grade selection markers in lactic acid bacteria. TAF Prev Med Bull 11(4), 499–510.
    • (2012) TAF Prev Med Bull , vol.11 , Issue.4 , pp. 499-510
    • He, S.1    Gong, F.2    Guo, Y.3    Zhang, D.4
  • 27
    • 0032917778 scopus 로고    scopus 로고
    • Immunomodulatory effects of Lactobacillus plantarum colonizing the intestine of gnotobiotic rats
    • Herias, M.V., Hessle, C., Telemo, E., Midtvedt, T., Hanson, L.A. and Wold, A.E. (1999) Immunomodulatory effects of Lactobacillus plantarum colonizing the intestine of gnotobiotic rats. Clin Exp Immunol 116, 283–290.
    • (1999) Clin Exp Immunol , vol.116 , pp. 283-290
    • Herias, M.V.1    Hessle, C.2    Telemo, E.3    Midtvedt, T.4    Hanson, L.A.5    Wold, A.E.6
  • 28
    • 0033996191 scopus 로고    scopus 로고
    • Antigen processing and presentation by intestinal epithelial cells – polarity and complexity
    • Hershberg, R.M. and Mayer, L.F. (2000) Antigen processing and presentation by intestinal epithelial cells – polarity and complexity. Immunol Today 21, 123–128.
    • (2000) Immunol Today , vol.21 , pp. 123-128
    • Hershberg, R.M.1    Mayer, L.F.2
  • 29
    • 0028751907 scopus 로고
    • Elemental speciation with liquid chromatography-inductively coupled plasma isotope dilution mass spectrometry
    • Heumann, K.G., Rottman, L. and Vogl, J. (1994) Elemental speciation with liquid chromatography-inductively coupled plasma isotope dilution mass spectrometry. J Anal At Spectrom 9, 1351–1355.
    • (1994) J Anal At Spectrom , vol.9 , pp. 1351-1355
    • Heumann, K.G.1    Rottman, L.2    Vogl, J.3
  • 31
    • 58149477054 scopus 로고    scopus 로고
    • Effect of trehalose on protein structure
    • Jain, N.K. and Roy, I. (2009) Effect of trehalose on protein structure. Protein Sci 18, 24–36.
    • (2009) Protein Sci , vol.18 , pp. 24-36
    • Jain, N.K.1    Roy, I.2
  • 32
    • 84955620666 scopus 로고    scopus 로고
    • New insight into the physiological role of bile salt hydrolase among intestinal bacteria from the genus Bifidobacterium
    • Jarocki, P., Podleśny, M., Glibowski, P. and Targoński, Z.A. (2014) New insight into the physiological role of bile salt hydrolase among intestinal bacteria from the genus Bifidobacterium. PLoS ONE 9(12), e114379.
    • (2014) PLoS ONE , vol.9 , Issue.12
    • Jarocki, P.1    Podleśny, M.2    Glibowski, P.3    Targoński, Z.A.4
  • 33
    • 84930664245 scopus 로고    scopus 로고
    • Oral administration of Lactococcus lactis expressing synthetic genes of myelin antigens in decreasing experimental autoimmune encephalomyelitis in rats
    • Kasarello, K., Kwiatkowska-Patzer, B., Lipkowski, A.W., Bardowski, J.K. and Szczepankowska, A.K. (2015) Oral administration of Lactococcus lactis expressing synthetic genes of myelin antigens in decreasing experimental autoimmune encephalomyelitis in rats. Med Sci Monit 21, 1587–1597.
    • (2015) Med Sci Monit , vol.21 , pp. 1587-1597
    • Kasarello, K.1    Kwiatkowska-Patzer, B.2    Lipkowski, A.W.3    Bardowski, J.K.4    Szczepankowska, A.K.5
  • 34
    • 0030721749 scopus 로고    scopus 로고
    • Controlled gene expression systems for lactic acid bacteria: transferable nisin-inducible expression cassettes for Lactococcus, Leuconostoc, and Lactobacillus spp
    • Kleerebezem, M., Beerthuyzen, M.M., Vaughan, E.E., de Vos, W.M. and Kuipers, O.P. (1997) Controlled gene expression systems for lactic acid bacteria: transferable nisin-inducible expression cassettes for Lactococcus, Leuconostoc, and Lactobacillus spp. Appl Environ Microbiol 63, 4581–4584.
    • (1997) Appl Environ Microbiol , vol.63 , pp. 4581-4584
    • Kleerebezem, M.1    Beerthuyzen, M.M.2    Vaughan, E.E.3    de Vos, W.M.4    Kuipers, O.P.5
  • 35
    • 0029063557 scopus 로고
    • Genetic marking of Lactococcus lactis shows its survival in the human gastrointestinal tract
    • Klijn, N., Weerkamp, A.H. and de Vos, W.M. (1995) Genetic marking of Lactococcus lactis shows its survival in the human gastrointestinal tract. Appl Environ Microbiol 61, 2771–2774.
    • (1995) Appl Environ Microbiol , vol.61 , pp. 2771-2774
    • Klijn, N.1    Weerkamp, A.H.2    de Vos, W.M.3
  • 36
    • 16244365147 scopus 로고    scopus 로고
    • Clinical and microbiological responses of volunteers to combined intranasal and oral inoculation with a Streptococcus gordonii carrier strain intended for future use as a group A Streptococcus vaccine
    • Kotloff, K.L., Wasserman, S.S., Jones, K.F., Livio, S., Hruby, D.E., Franke, C.A. and Fischetti, V.A. (2005) Clinical and microbiological responses of volunteers to combined intranasal and oral inoculation with a Streptococcus gordonii carrier strain intended for future use as a group A Streptococcus vaccine. Infect Immun 3, 2360–2366.
    • (2005) Infect Immun , vol.3 , pp. 2360-2366
    • Kotloff, K.L.1    Wasserman, S.S.2    Jones, K.F.3    Livio, S.4    Hruby, D.E.5    Franke, C.A.6    Fischetti, V.A.7
  • 37
    • 0030964959 scopus 로고    scopus 로고
    • Comparison of the oral, rectal, and vaginal immunization routes for induction of antibodies in rectal and genital tract secretions of women
    • Kozlowski, P.A., Cu-Uvin, S., Neutra, M.R. and Flanigan, T.P. (1997) Comparison of the oral, rectal, and vaginal immunization routes for induction of antibodies in rectal and genital tract secretions of women. Infect Immun 65, 1387–1394.
    • (1997) Infect Immun , vol.65 , pp. 1387-1394
    • Kozlowski, P.A.1    Cu-Uvin, S.2    Neutra, M.R.3    Flanigan, T.P.4
  • 38
    • 33645796224 scopus 로고    scopus 로고
    • Mucosal immunization with surface-display severe acute respiratory syndrome Coronavirus spike protein on Lactobaclillus casei induces neutralizing antibodies in mice
    • Lee, J.S., Poo, H., Han, D.P., Hong, S.P., Kim, K., Cho, M.W., Kim, E., Sung, M.H. et al. (2006) Mucosal immunization with surface-display severe acute respiratory syndrome Coronavirus spike protein on Lactobaclillus casei induces neutralizing antibodies in mice. J Virol 80, 4079–4087.
    • (2006) J Virol , vol.80 , pp. 4079-4087
    • Lee, J.S.1    Poo, H.2    Han, D.P.3    Hong, S.P.4    Kim, K.5    Cho, M.W.6    Kim, E.7    Sung, M.H.8
  • 39
    • 84961577123 scopus 로고    scopus 로고
    • Dead Lactobacillus plantarum stimulates and skews immune responses toward T helper 1 and 17 polarizations in RAW 264.7 cells and mouse splenocytes
    • Lee, H.A., Kim, H., Lee, K.W. and Park, K.Y. (2016) Dead Lactobacillus plantarum stimulates and skews immune responses toward T helper 1 and 17 polarizations in RAW 264.7 cells and mouse splenocytes. J Microbiol Biotechnol 26, 469–476.
    • (2016) J Microbiol Biotechnol , vol.26 , pp. 469-476
    • Lee, H.A.1    Kim, H.2    Lee, K.W.3    Park, K.Y.4
  • 40
    • 0027240994 scopus 로고
    • Lactobacilli and the normal human anaerobic microflora
    • Lidbeck, A. and Nord, C.E. (1993) Lactobacilli and the normal human anaerobic microflora. Clin Infect Dis 16, S181–S187.
    • (1993) Clin Infect Dis , vol.16 , pp. S181-S187
    • Lidbeck, A.1    Nord, C.E.2
  • 41
    • 0031602351 scopus 로고    scopus 로고
    • Is IgG2a a good Th1 marker in mice
    • Martin, R.M. and Lew, A.M. (1998) Is IgG2a a good Th1 marker in mice. Immunol Today 19, 49.
    • (1998) Immunol Today , vol.19 , pp. 49
    • Martin, R.M.1    Lew, A.M.2
  • 42
    • 0029118119 scopus 로고
    • Mucosal and systemic immune responses to a recombinant protein expressed on the surface of the oral commensal bacterium Streptococcus gordonii after oral colonisation
    • Medaglini, D., Pozzi, G., King, T.P. and Fischetti, V.A. (1995) Mucosal and systemic immune responses to a recombinant protein expressed on the surface of the oral commensal bacterium Streptococcus gordonii after oral colonisation. Proc Natl Acad Sci USA 92, 6868–6872.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6868-6872
    • Medaglini, D.1    Pozzi, G.2    King, T.P.3    Fischetti, V.A.4
  • 46
    • 0023243066 scopus 로고
    • The common mucosal immune system and current strategies for induction of immune responses in external secretions
    • Mestecky, J. (1987) The common mucosal immune system and current strategies for induction of immune responses in external secretions. J Clin Immunol 7, 265.
    • (1987) J Clin Immunol , vol.7 , pp. 265
    • Mestecky, J.1
  • 47
    • 84890600756 scopus 로고    scopus 로고
    • Surface proteome analysis of a natural isolate of Lactococcus lctis reveals the presence of pili able to bind human intestinal epithelial cells
    • Meyrand, M., Guillot, A., Goin, M., Furlan, S., Armalyte, J., Kulakauskas, S., Cortes-Perez, N.G., Thomas, G. et al. (2013) Surface proteome analysis of a natural isolate of Lactococcus lctis reveals the presence of pili able to bind human intestinal epithelial cells. Mol Cell Proteomics 12, 3935–3947.
    • (2013) Mol Cell Proteomics , vol.12 , pp. 3935-3947
    • Meyrand, M.1    Guillot, A.2    Goin, M.3    Furlan, S.4    Armalyte, J.5    Kulakauskas, S.6    Cortes-Perez, N.G.7    Thomas, G.8
  • 48
    • 84977643680 scopus 로고    scopus 로고
    • Display of recombinant proteins at the surface of lactic acid bacteria: strategies and applications
    • Michon, C., Langella, P., Eijsink, V.G.H., Mathiesen, G. and Chatel, J.M. (2016) Display of recombinant proteins at the surface of lactic acid bacteria: strategies and applications. Microb Cell Fact 15, 70.
    • (2016) Microb Cell Fact , vol.15 , pp. 70
    • Michon, C.1    Langella, P.2    Eijsink, V.G.H.3    Mathiesen, G.4    Chatel, J.M.5
  • 49
    • 0029807059 scopus 로고    scopus 로고
    • Production of human tumor necrosis factor alpha, interleukin-6, and interleukin-10 is induced by lactic acid bacteria
    • Miettinen, M., Vuopio-Varkila, J. and Varkila, K. (1996) Production of human tumor necrosis factor alpha, interleukin-6, and interleukin-10 is induced by lactic acid bacteria. Infect Immun 64, 5403–5405.
    • (1996) Infect Immun , vol.64 , pp. 5403-5405
    • Miettinen, M.1    Vuopio-Varkila, J.2    Varkila, K.3
  • 50
    • 0000238548 scopus 로고
    • Effect of feeding fermented milks on the pulmonary macrophage activity in mice
    • Moineau, S. and Goulet, J. (1991) Effect of feeding fermented milks on the pulmonary macrophage activity in mice. Milchwissenschaft 46, 551–554.
    • (1991) Milchwissenschaft , vol.46 , pp. 551-554
    • Moineau, S.1    Goulet, J.2
  • 51
    • 0000689557 scopus 로고    scopus 로고
    • Oral tolerance: physiological basis and clinical applications
    • In, ed., Ogra, P.L., Mestecky, J., Lamm, M.E., Strober, W., Bienenstock, J., McGhee, J.R., 2nd edn, New York, NY, Academic Press
    • Mowat, A.M. and Weiner, H.L. (1999) Oral tolerance: physiological basis and clinical applications. In Mucosal Immunology ed. Ogra, P.L., Mestecky, J., Lamm, M.E., Strober, W., Bienenstock, J. and McGhee, J.R., 2nd edn. pp. 587–618. New York, NY: Academic Press.
    • (1999) Mucosal Immunology , pp. 587-618
    • Mowat, A.M.1    Weiner, H.L.2
  • 52
    • 0023908178 scopus 로고
    • Interferon-gamma, the activated macrophage, and host defense against microbial challenge
    • Murray, H.W. (1988) Interferon-gamma, the activated macrophage, and host defense against microbial challenge. Ann Intern Med 108, 595–608.
    • (1988) Ann Intern Med , vol.108 , pp. 595-608
    • Murray, H.W.1
  • 54
    • 0035074535 scopus 로고    scopus 로고
    • Vaccination strategies for mucosal immune responses
    • Ogra, P.L., Faden, H. and Welliver, R.C. (2001) Vaccination strategies for mucosal immune responses. Clin Microbiol Rev 14, 430–445.
    • (2001) Clin Microbiol Rev , vol.14 , pp. 430-445
    • Ogra, P.L.1    Faden, H.2    Welliver, R.C.3
  • 55
    • 33646151139 scopus 로고    scopus 로고
    • Induction of systemic and mucosal immune response and decrease in Streptococcus pneumoniae colonization by nasal inoculation of mice with recombinant lactic acid bacteria expressing pneumococcal surface antigen A
    • Oliveira, M.L., Areas, A.P., Campos, I.B., Monedero, V., Perez-Martinez, G., Miyaji, E.N., Leite, L.C., Aire, K.S. et al. (2006) Induction of systemic and mucosal immune response and decrease in Streptococcus pneumoniae colonization by nasal inoculation of mice with recombinant lactic acid bacteria expressing pneumococcal surface antigen A. Microbes Infect 8, 1016–1024.
    • (2006) Microbes Infect , vol.8 , pp. 1016-1024
    • Oliveira, M.L.1    Areas, A.P.2    Campos, I.B.3    Monedero, V.4    Perez-Martinez, G.5    Miyaji, E.N.6    Leite, L.C.7    Aire, K.S.8
  • 56
    • 85024874397 scopus 로고    scopus 로고
    • Persistence of orally administered Lactobacillus strains in the gut of infant mice
    • Ozawa, K., Fujiwara, R., Watanbe, K. and Sonoyama, K. (2012) Persistence of orally administered Lactobacillus strains in the gut of infant mice. Biosci Microbiota Food Health 31, 85–91.
    • (2012) Biosci Microbiota Food Health , vol.31 , pp. 85-91
    • Ozawa, K.1    Fujiwara, R.2    Watanbe, K.3    Sonoyama, K.4
  • 57
    • 0029537471 scopus 로고
    • Enhancement of host resistance against Salmonella typhimurium in mice fed a diet supplemented with yoghurt or milks fermented with various Lactobacillus casei strains
    • Paubert-Braquet, M., Gan, X.H., Gaudichon, C., Hedef, N., Serikoff, A., Bouley, C., Bonavida, B. and Braquet, P. (1995) Enhancement of host resistance against Salmonella typhimurium in mice fed a diet supplemented with yoghurt or milks fermented with various Lactobacillus casei strains. Int J Immunother 11, 153–161.
    • (1995) Int J Immunother , vol.11 , pp. 153-161
    • Paubert-Braquet, M.1    Gan, X.H.2    Gaudichon, C.3    Hedef, N.4    Serikoff, A.5    Bouley, C.6    Bonavida, B.7    Braquet, P.8
  • 58
    • 0003075395 scopus 로고
    • Probiotics and the immune state
    • In, ed., Fuller, R., London, Chapman and Hall
    • Perdigón, G. and Alvarez, S. (1992) Probiotics and the immune state. In Probiotics, the Scientific Basis ed. Fuller, R., pp. 145–180. London: Chapman and Hall.
    • (1992) Probiotics, the Scientific Basis , pp. 145-180
    • Perdigón, G.1    Alvarez, S.2
  • 59
    • 0033142704 scopus 로고    scopus 로고
    • Study of the possible mechanisms involved in the mucosal immune system activation by lactic acid bacteria
    • Perdigón, G., Vintiñi, E., Alvarez, S., Medina, M. and Medici, M. (1999) Study of the possible mechanisms involved in the mucosal immune system activation by lactic acid bacteria. J Dairy Sci 82, 1108–1114.
    • (1999) J Dairy Sci , vol.82 , pp. 1108-1114
    • Perdigón, G.1    Vintiñi, E.2    Alvarez, S.3    Medina, M.4    Medici, M.5
  • 61
    • 80052633525 scopus 로고    scopus 로고
    • Food-grade gene expression in lactic acid bacteria
    • Peterbauer, C., Meichsberger, T. and Haltrich, D. (2011) Food-grade gene expression in lactic acid bacteria. Biotechnol J 6, 1147–1161.
    • (2011) Biotechnol J , vol.6 , pp. 1147-1161
    • Peterbauer, C.1    Meichsberger, T.2    Haltrich, D.3
  • 62
    • 0029200344 scopus 로고
    • Protective ability of certain lactic acid bacteria against an infection with Candida albicans in a mouse immunosuppression model by corticoid
    • de Petrino, S.F., de Jorrrat, M.E.B.B., Meson, O. and Perdigón, G. (1995) Protective ability of certain lactic acid bacteria against an infection with Candida albicans in a mouse immunosuppression model by corticoid. Food Agric Immunol 7, 365–373.
    • (1995) Food Agric Immunol , vol.7 , pp. 365-373
    • de Petrino, S.F.1    de Jorrrat, M.E.B.B.2    Meson, O.3    Perdigón, G.4
  • 63
    • 79956039870 scopus 로고    scopus 로고
    • Advances in fish vaccine delivery
    • Plant, K.P. and Lapatra, S.E. (2011) Advances in fish vaccine delivery. Dev Comp Immunol 35, 1256–1262.
    • (2011) Dev Comp Immunol , vol.35 , pp. 1256-1262
    • Plant, K.P.1    Lapatra, S.E.2
  • 65
    • 84907685071 scopus 로고    scopus 로고
    • Lactococcus lactis IBB477 presenting adhesive and muco-adhesive properties as a candidate carrier strain for oral vaccination against influenza virus
    • Radziwill-Bienkowska, J.M., Zochowska, D., Bardowski, J.K., Mercier-Bonin, M. and Kowalczyk, M. (2014) Lactococcus lactis IBB477 presenting adhesive and muco-adhesive properties as a candidate carrier strain for oral vaccination against influenza virus. Acta Biochim Pol 61, 603–607.
    • (2014) Acta Biochim Pol , vol.61 , pp. 603-607
    • Radziwill-Bienkowska, J.M.1    Zochowska, D.2    Bardowski, J.K.3    Mercier-Bonin, M.4    Kowalczyk, M.5
  • 67
    • 0033984376 scopus 로고    scopus 로고
    • Immunogenicity of the B Monomer of Escherichia coli HeatLabile toxin expressed on the surface of Streptococcus gordonii
    • Ricci, S., Medalgini, D., Rush, C.M., Marcello, A., Peppeloni, S., Manganelli, R., Palu, G. and Pozzi, G. (2000) Immunogenicity of the B Monomer of Escherichia coli HeatLabile toxin expressed on the surface of Streptococcus gordonii. Infect Immun 68, 760–766.
    • (2000) Infect Immun , vol.68 , pp. 760-766
    • Ricci, S.1    Medalgini, D.2    Rush, C.M.3    Marcello, A.4    Peppeloni, S.5    Manganelli, R.6    Palu, G.7    Pozzi, G.8
  • 68
    • 60849121449 scopus 로고    scopus 로고
    • Immunomodulatory properties of Lactobacillus plantarum and its use as a recombinant vaccine against mite allergy
    • Rigaux, P., Daniel, C., Hisbergues, M., Muraille, E., Hols, P., Pot, B., Pestel, J. and Jacquet, A. (2009) Immunomodulatory properties of Lactobacillus plantarum and its use as a recombinant vaccine against mite allergy. Allergy 64, 406–414.
    • (2009) Allergy , vol.64 , pp. 406-414
    • Rigaux, P.1    Daniel, C.2    Hisbergues, M.3    Muraille, E.4    Hols, P.5    Pot, B.6    Pestel, J.7    Jacquet, A.8
  • 70
    • 0003137952 scopus 로고    scopus 로고
    • Expression of vaccine antigens in Lactobacillus
    • In, ed., Pozzi, G., Wells, J.M, Landes, Austin, TX, Biotechnology Intelligence Unit
    • Rush, C.M., Mercenier, A. and Pozzi, G. (1997) Expression of vaccine antigens in Lactobacillus. In Gram-Positive Bacteria. Vaccine Vehicles for Mucosal Immunisation. ed. Pozzi, G. and Wells, J.M. pp. 107–144. Landes, Austin, TX: Biotechnology Intelligence Unit.
    • (1997) Gram-Positive Bacteria. Vaccine Vehicles for Mucosal Immunisation , pp. 107-144
    • Rush, C.M.1    Mercenier, A.2    Pozzi, G.3
  • 71
    • 0029912668 scopus 로고    scopus 로고
    • Clinical uses of probiotics for stabilising the gut mucosal barrier: successful strains and future challenges
    • Salminen, S., Isolauri, E. and Salminen, E. (1996) Clinical uses of probiotics for stabilising the gut mucosal barrier: successful strains and future challenges. Anton van Leeuwen 70, 347–358.
    • (1996) Anton van Leeuwen , vol.70 , pp. 347-358
    • Salminen, S.1    Isolauri, E.2    Salminen, E.3
  • 73
  • 74
    • 0035055339 scopus 로고    scopus 로고
    • Oral Immunization with Recombinant Streptococcus gordonii expressing porphyromonas gingivalis FimA domains
    • Sharma, A., Honma, K., Evans, R.T., Hruby, D.E. and Genco, R.J. (2001) Oral Immunization with Recombinant Streptococcus gordonii expressing porphyromonas gingivalis FimA domains. Infect Immun 69, 2928–2934.
    • (2001) Infect Immun , vol.69 , pp. 2928-2934
    • Sharma, A.1    Honma, K.2    Evans, R.T.3    Hruby, D.E.4    Genco, R.J.5
  • 75
    • 84925781319 scopus 로고    scopus 로고
    • Gene exchange of ThyA for interleukin-10 eecures live GMO bacterial therapeutics
    • Steidler, L. (2003) Gene exchange of ThyA for interleukin-10 eecures live GMO bacterial therapeutics. Discov Med 3, 49–51.
    • (2003) Discov Med , vol.3 , pp. 49-51
    • Steidler, L.1
  • 78
    • 84907695969 scopus 로고    scopus 로고
    • Expression of avian influenza haemagglutinin (H5) and chicken interleukin 2 (chIL-2) under control of the ptcB promoter in Lactococcus lactis
    • Szatraj, K., Szczepankowska, A.K., Sączyńska, V., Florys, K., Gromadzka, B., Łepek, K., Płucienniczak, G., Szewczyk, B. et al. (2014) Expression of avian influenza haemagglutinin (H5) and chicken interleukin 2 (chIL-2) under control of the ptcB promoter in Lactococcus lactis. Acta Biochim Pol 61, 609–614.
    • (2014) Acta Biochim Pol , vol.61 , pp. 609-614
    • Szatraj, K.1    Szczepankowska, A.K.2    Sączyńska, V.3    Florys, K.4    Gromadzka, B.5    Łepek, K.6    Płucienniczak, G.7    Szewczyk, B.8
  • 79
    • 0040653354 scopus 로고    scopus 로고
    • An introduction
    • In, ed., Tizard, I.R, 6th edn, Philadelphia, PA, Saunders W.B. Company
    • Tizard, I.R. (2000) An introduction. In: Veterinary immunology ed. Tizard, I.R. 6th edn. pp. 210–221. Philadelphia, PA: Saunders W.B. Company.
    • (2000) Veterinary immunology , pp. 210-221
    • Tizard, I.R.1
  • 80
    • 77949914618 scopus 로고    scopus 로고
    • Characterisation and transferability of antibiotic resistance genes from lactic acid bacteria isolated from Irish pork and beef abattoirs
    • Toomey, N., Bolton, D. and Fanning, S. (2010) Characterisation and transferability of antibiotic resistance genes from lactic acid bacteria isolated from Irish pork and beef abattoirs. Res Microbiol 161, 127–135.
    • (2010) Res Microbiol , vol.161 , pp. 127-135
    • Toomey, N.1    Bolton, D.2    Fanning, S.3
  • 81
    • 0013361193 scopus 로고
    • Effect of inclusion of microbial culture in barley-based diets fed to laying hens
    • Tortuero, F. and Fernandez, E. (1995) Effect of inclusion of microbial culture in barley-based diets fed to laying hens. Anim Feed Sci Tec 53, 255–265.
    • (1995) Anim Feed Sci Tec , vol.53 , pp. 255-265
    • Tortuero, F.1    Fernandez, E.2
  • 82
    • 0032537538 scopus 로고    scopus 로고
    • Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes
    • Tynkkynen, S., Singh, K.V. and Varmanen, P. (1998) Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 41, 195–204.
    • (1998) Int J Food Microbiol , vol.41 , pp. 195-204
    • Tynkkynen, S.1    Singh, K.V.2    Varmanen, P.3
  • 83
    • 77954630921 scopus 로고    scopus 로고
    • Amylase production on submerged fermentationby Bacillus spp
    • Vidhyalakshmi, R., Parantham, R. and Indhumathi, J. (2009) Amylase production on submerged fermentationby Bacillus spp. World J Chem 4, 89–91.
    • (2009) World J Chem , vol.4 , pp. 89-91
    • Vidhyalakshmi, R.1    Parantham, R.2    Indhumathi, J.3
  • 84
    • 0028226559 scopus 로고
    • New strategies for using mucosal vaccination to achieve more effective immunisation
    • Walker, R.I. (1994) New strategies for using mucosal vaccination to achieve more effective immunisation. Vaccine 12, 387–400.
    • (1994) Vaccine , vol.12 , pp. 387-400
    • Walker, R.I.1
  • 85
    • 84876408364 scopus 로고    scopus 로고
    • Development of a Streptococcus gordonii vaccine strain expressing Schisostoma japonicum Sj-F1 and evaluation of using this strain for intranasal immunization in mice
    • Wang, L., Liu, W., Yang, M., Peng, D. and Chen, L. (2013) Development of a Streptococcus gordonii vaccine strain expressing Schisostoma japonicum Sj-F1 and evaluation of using this strain for intranasal immunization in mice. Parasitol Res 112, 1701–1708.
    • (2013) Parasitol Res , vol.112 , pp. 1701-1708
    • Wang, L.1    Liu, W.2    Yang, M.3    Peng, D.4    Chen, L.5
  • 86
    • 0000484862 scopus 로고
    • Progress in the development of mucosal vaccines based on Lactococcus lactis
    • Wells, J.M., Norton, P.M. and le Page, R.W.F. (1995) Progress in the development of mucosal vaccines based on Lactococcus lactis. Int Dairy J 5, 1071–1079.
    • (1995) Int Dairy J , vol.5 , pp. 1071-1079
    • Wells, J.M.1    Norton, P.M.2    le Page, R.W.F.3
  • 88
    • 84880071232 scopus 로고    scopus 로고
    • Geneva, Switzerland, WHO Press, immunization/global_vaccine_action_plan/en/
    • World Health Organization. Global Vaccine Action Plan: 2011–2020. Geneva, Switzerland: WHO Press; 2013. http://www.who.int/ immunization/global_vaccine_action_plan/en/
    • (2013) Global Vaccine Action Plan: 2011–2020
  • 89
    • 84891825111 scopus 로고    scopus 로고
    • Probiotic modulation of dendritic cell function is influenced by ageing
    • You, J., Dong, H., Mann, E.R., Knight, S.C. and Yaqoob, P. (2014) Probiotic modulation of dendritic cell function is influenced by ageing. Immunobiology 219, 138–148.
    • (2014) Immunobiology , vol.219 , pp. 138-148
    • You, J.1    Dong, H.2    Mann, E.R.3    Knight, S.C.4    Yaqoob, P.5
  • 90
    • 84863075697 scopus 로고    scopus 로고
    • Use of pre-S protein-containing hepatitis B virus surface antigens and a powerful adjuvant to develop an immune therapy for chronic hepatitis B virus infection
    • Yum, J.S., Ahn, B.C., Jin Jo, H.J., Kim, D.Y., Kim, K.H., Kim, H.S., Chul Sung, Y.C., Yoon, J. et al. (2012) Use of pre-S protein-containing hepatitis B virus surface antigens and a powerful adjuvant to develop an immune therapy for chronic hepatitis B virus infection. Clin Vaccine Immunol 19, 120–127.
    • (2012) Clin Vaccine Immunol , vol.19 , pp. 120-127
    • Yum, J.S.1    Ahn, B.C.2    Jin Jo, H.J.3    Kim, D.Y.4    Kim, K.H.5    Kim, H.S.6    Chul Sung, Y.C.7    Yoon, J.8
  • 91
    • 84919705414 scopus 로고    scopus 로고
    • Expression of Helicobacter pylori urease B on the surface of Bacillus subtilis spores
    • Zhou, Z., Gong, S., Li, X.M., Yangm, Y., Guan, R., Zhou, S., Yao, S., Xie, Y. et al. (2015) Expression of Helicobacter pylori urease B on the surface of Bacillus subtilis spores. J Med Microbiol 64, 104–110.
    • (2015) J Med Microbiol , vol.64 , pp. 104-110
    • Zhou, Z.1    Gong, S.2    Li, X.M.3    Yangm, Y.4    Guan, R.5    Zhou, S.6    Yao, S.7    Xie, Y.8


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