Molecular Insight into Evolution of Symbiosis between Breast-Fed Infants and a Member of the Human Gut Microbiome Bifidobacterium longum

Cell Chemical Biology

Volumn 24, Issue 4, 2017, Pages 515-524.e5

  Yamada, Chihaya ^a,b   Gotoh, Aina ^b   Sakanaka, Mikiyasu ^c   Hattie, Mitchell ^d   Stubbs, Keith A ^d   Katayama Ikegami, Ayako ^c   Hirose, Junko ^e   Kurihara, Shin ^c   Arakawa, Takatoshi ^a   Kitaoka, Motomitsu ^f   Okuda, Shujiro ^g   Katayama, Takane ^b,c   Fushinobu, Shinya ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c ISHIKAWA PREFECTURAL UNIVERSITY   (Japan)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^e UNIVERSITY OF SHIGA PREFECTURE   (Japan)

^f FOOD RESEARCH INSTITUTE   (Japan)

^g NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

bifidobacteria; glycoside hydrolase; human microbe co evolution; human microbe symbiosis; human milk oligosaccharides; infant gut microbiota; inhibitors; lacto N biosidase; lacto N tetraose; X ray crystallography

Indexed keywords

ENZYME; GLYCOSIDASE; LNBX PROTEIN; UNCLASSIFIED DRUG; GLYCOSIDASE INHIBITOR; OLIGOSACCHARIDE; RNA 16S;

ARTICLE; BACTERIAL GROWTH; BIFIDOBACTERIUM LONGUM; BREAST MILK; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; HEREDITY; HUMAN; INFANT; INTESTINE FLORA; MOLECULAR EVOLUTION; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; SYMBIOSIS; BINDING SITE; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; FECES; GENETICS; GROWTH, DEVELOPMENT AND AGING; KINETICS; METABOLISM; MICROBIOLOGY; MOLECULAR DOCKING; SITE DIRECTED MUTAGENESIS; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

BIFIDOBACTERIUM LONGUM; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; EVOLUTION, MOLECULAR; FECES; GASTROINTESTINAL MICROBIOME; GLYCOSIDE HYDROLASE INHIBITORS; GLYCOSIDE HYDROLASES; HUMANS; INFANT; KINETICS; MILK, HUMAN; MOLECULAR DOCKING SIMULATION; MUTAGENESIS, SITE-DIRECTED; OLIGOSACCHARIDES; RNA, RIBOSOMAL, 16S; SUBSTRATE SPECIFICITY; SYMBIOSIS;

EID: 85017202260     PISSN: 24519456     EISSN: 24519448     Source Type: Journal    
DOI: 10.1016/j.chembiol.2017.03.012     Document Type: Article

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