CRISPR-Cas systems exploit viral DNA injection to establish and maintain adaptive immunity

Nature

Volumn 544, Issue 7648, 2017, Pages 101-104

  Modell, Joshua W ^a   Jiang, Wenyan ^a   Marraffini, Luciano A ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA; BACTERIOPHAGE RECEPTOR; CRISPR ASSOCIATED PROTEIN;

BACTERIOPHAGE; BACTERIUM; CELLS AND CELL COMPONENTS; DNA; GENETIC ANALYSIS; GENOME; IMMUNE RESPONSE; IMMUNITY; LIFE CYCLE; PLASMID;

ADAPTIVE IMMUNITY; ARTICLE; BACTERIAL CELL; BACTERIOPHAGE; CONTROLLED STUDY; CRISPR CAS SYSTEM; DNA PACKAGING; DNA REPLICATION; DNA VIRUS; GENOMICS; IMMUNE RESPONSE; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; BACILLUS PHAGE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENETIC TRANSFECTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; METABOLISM; MUTATION; PHYSIOLOGY; TIME FACTOR; VIROLOGY;

PROKARYOTA; STAPHYLOCOCCUS AUREUS;

ATTACHMENT SITES, MICROBIOLOGICAL; BACILLUS PHAGES; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; DNA, VIRAL; MUTATION; STAPHYLOCOCCUS AUREUS; TIME FACTORS; TRANSFECTION;

EID: 85017152413     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature21719     Document Type: Article

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