Structural insights into adiponectin receptors suggest ceramidase activity

Nature

Volumn 544, Issue 7648, 2017, Pages 120-123

  Vasiliauskaité Brooks, Ieva ^a   Sounier, Remy ^a   Rochaix, Pascal ^a   Bellot, Gaëtan ^a   Fortier, Mathieu ^a   Hoh, François ^a   De Colibus, Luigi ^b   Bechara, Chérine ^c   Saied, Essa M ^d,e   Arenz, Christoph ^d   Leyrat, Cédric ^a   Granier, Sébastien ^a  

^a UNIV MONTPELLIER   (France)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITÉ DE MONTPELLIER   (France)

^d HUMBOLDT UNIVERSITY   (Germany)

^e Suez Canal University   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN RECEPTOR; ADIPONECTIN RECEPTOR 1; AMIDE; CARBONYL DERIVATIVE; CERAMIDASE; CERAMIDE; HYDROXIDE; ZINC; ADIPONECTIN; ADIPOR1 PROTEIN, HUMAN; ADIPOR2 PROTEIN, HUMAN; FATTY ACID; HYDROXIDE ION;

CHEMICAL BINDING; CRYSTAL STRUCTURE; ENZYME ACTIVITY; FATTY ACID; GENE EXPRESSION; HYDROLYSIS; HYDROXIDE; METABOLISM; MOLECULAR ANALYSIS; PROTEIN;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; HYDROLYSIS; INNER MEMBRANE; MOLECULAR DYNAMICS; NUCLEOPHILICITY; PRIORITY JOURNAL; BINDING SITE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECTS; ENZYME ACTIVE SITE; HUMAN; METABOLISM; MOLECULAR MODEL; PROTEIN DOMAIN; X RAY CRYSTALLOGRAPHY;

ADIPONECTIN; BINDING SITES; CATALYTIC DOMAIN; CERAMIDES; CRYSTALLOGRAPHY, X-RAY; FATTY ACIDS, NONESTERIFIED; HUMANS; HYDROLYSIS; HYDROXIDES; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN DOMAINS; RECEPTORS, ADIPONECTIN; ZINC;

EID: 85017122497     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature21714     Document Type: Article

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