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Volumn 7, Issue 12, 2009, Pages

Scientific Opinion on marine biotoxins in shellfish – Palytoxin group
[No Author Info available]

Author keywords

acute reference dose; human health; Marine biotoxins; methods of analysis; mouse bioassay (MBA); mussels; palytoxin (PlTX) toxin group toxins; portion size; risk assessment; sea urchins; shellfish

Indexed keywords


EID: 85017103208     PISSN: None     EISSN: 18314732     Source Type: Journal    
DOI: 10.2903/j.efsa.2009.1393     Document Type: Article
Times cited : (94)

References (108)
  • 1
    • 0023870328 scopus 로고
    • Human fatality due to ingestion of the crab Demania reynaudii that contained a palytoxin-like toxin
    • Alcala AC, Alcala LC, Garth JS, Yasumura D, Yasumoto T, 1988. Human fatality due to ingestion of the crab Demania reynaudii that contained a palytoxin-like toxin. Toxicon 26 (1), 105–107.
    • (1988) Toxicon , vol.26 , Issue.1 , pp. 105-107
    • Alcala, A.C.1    Alcala, L.C.2    Garth, J.S.3    Yasumura, D.4    Yasumoto, T.5
  • 2
    • 39149140730 scopus 로고    scopus 로고
    • First episode of shellfish contamination by palytoxin-like compounds from Ostreopsis species (Aegean Sea, Greece)
    • Aligizaki K, Katikou P, Nikolaidis G, Panou A, 2008. First episode of shellfish contamination by palytoxin-like compounds from Ostreopsis species (Aegean Sea, Greece). Toxicon 51 (3), 418–427.
    • (2008) Toxicon , vol.51 , Issue.3 , pp. 418-427
    • Aligizaki, K.1    Katikou, P.2    Nikolaidis, G.3    Panou, A.4
  • 4
    • 1842736450 scopus 로고    scopus 로고
    • Large diameter of palytoxin-induced Na/K pump channels and modulation of palytoxin interaction by Na/K pump ligands
    • Artigas P, Gadsby DC, 2004. Large diameter of palytoxin-induced Na/K pump channels and modulation of palytoxin interaction by Na/K pump ligands. The Journal of General Physiology 123 (4), 357–376.
    • (2004) The Journal of General Physiology , vol.123 , Issue.4 , pp. 357-376
    • Artigas, P.1    Gadsby, D.C.2
  • 6
    • 0028414112 scopus 로고
    • A hemolytic test to assay toxins excreted by the marine dinoflagellate Gyrodinium cf. aureolum
    • Arzul G, Gentien P, Crassous MP, 1994. A hemolytic test to assay toxins excreted by the marine dinoflagellate Gyrodinium cf. aureolum. Water Research 28, 961–965.
    • (1994) Water Research , vol.28 , pp. 961-965
    • Arzul, G.1    Gentien, P.2    Crassous, M.P.3
  • 9
    • 0027160539 scopus 로고
    • A rapid and sensitive hemolysis neutralization assay for palytoxins
    • Bignami GS, 1993. A rapid and sensitive hemolysis neutralization assay for palytoxins. Toxicon 31 (6), 817–820.
    • (1993) Toxicon , vol.31 , Issue.6 , pp. 817-820
    • Bignami, G.S.1
  • 12
    • 50949107209 scopus 로고    scopus 로고
    • Comparative study of the use of neuroblastoma cells (Neuro-2a) and neuroblastomaxglioma hybrid cells (NG108-15) for the toxic effect quantification of marine toxins
    • Cañete E, Diogène J, 2008. Comparative study of the use of neuroblastoma cells (Neuro-2a) and neuroblastomaxglioma hybrid cells (NG108-15) for the toxic effect quantification of marine toxins. Toxicon 52 (4), 541–550.
    • (2008) Toxicon , vol.52 , Issue.4 , pp. 541-550
    • Cañete, E.1    Diogène, J.2
  • 14
    • 84912833441 scopus 로고
    • Palytoxin-its action on erythrocytes and rat mast-cells
    • p
    • Chhatwal GS, Ahnerthilger G, Beress L, 1982. Palytoxin-its action on erythrocytes and rat mast-cells. Toxicon 20 (1), p. 62.
    • (1982) Toxicon , vol.20 , Issue.1 , pp. 62
    • Chhatwal, G.S.1    Ahnerthilger, G.2    Beress, L.3
  • 16
    • 33748482635 scopus 로고    scopus 로고
    • The Genoa 2005 outbreak. Determination of putative palytoxin in Mediterranean Ostreopsis ovata by a new liquid chromatography tandem mass spectrometry method
    • Ciminiello P, Dell'Aversano C, Fattorusso E, Forino M, Magno GS, Tartaglione L, Grillo C, Melchiorre N, 2006. The Genoa 2005 outbreak. Determination of putative palytoxin in Mediterranean Ostreopsis ovata by a new liquid chromatography tandem mass spectrometry method. Analytical Chemistry 78 (17), 6153–6159.
    • (2006) Analytical Chemistry , vol.78 , Issue.17 , pp. 6153-6159
    • Ciminiello, P.1    Dell'Aversano, C.2    Fattorusso, E.3    Forino, M.4    Magno, G.S.5    Tartaglione, L.6    Grillo, C.7    Melchiorre, N.8
  • 28
    • 0025270222 scopus 로고
    • Palytoxin acidifies chick cardiac cells and activates the Na+/H+ antiporter
    • Frelin C, Vigne P, Breittmayer JP, 1990. Palytoxin acidifies chick cardiac cells and activates the Na+/H+ antiporter. FEBS Letters 264 (1), 63–66.
    • (1990) FEBS Letters , vol.264 , Issue.1 , pp. 63-66
    • Frelin, C.1    Vigne, P.2    Breittmayer, J.P.3
  • 29
    • 0028842073 scopus 로고
    • Palytoxin. Recent electrophysiological and pharmacological evidence for several mechanisms of action
    • Frelin C, Van Renterghem C, 1995. Palytoxin. Recent electrophysiological and pharmacological evidence for several mechanisms of action. General Pharmacology 26 (1), 33–37.
    • (1995) General Pharmacology , vol.26 , Issue.1 , pp. 33-37
    • Frelin, C.1    Van Renterghem, C.2
  • 30
    • 0022965231 scopus 로고
    • Palytoxin is a non-12-O-tetradecanoylphorbol-13-acetate type tumor promoter in two-stage mouse skin carcinogenesis
    • Fujiki H, Suganuma M, Nakayasu M, Hakii H, Horiuchi T, Takayama S, Sugimura T, 1986. Palytoxin is a non-12-O-tetradecanoylphorbol-13-acetate type tumor promoter in two-stage mouse skin carcinogenesis. Carcinogenesis 7 (5), 707–710.
    • (1986) Carcinogenesis , vol.7 , Issue.5 , pp. 707-710
    • Fujiki, H.1    Suganuma, M.2    Nakayasu, M.3    Hakii, H.4    Horiuchi, T.5    Takayama, S.6    Sugimura, T.7
  • 31
    • 61449428171 scopus 로고    scopus 로고
    • Review. Peering into an ATPase ion pump with single-channel recordings. Philosophical transactions of the Royal Society of London. Series B
    • Gadsby DC, Takeuchi A, Artigas P, Reyes N, 2009. Review. Peering into an ATPase ion pump with single-channel recordings. Philosophical transactions of the Royal Society of London. Series B, Biological Sciences 364 (1514), 229–238.
    • (2009) Biological Sciences , vol.364 , Issue.1514 , pp. 229-238
    • Gadsby, D.C.1    Takeuchi, A.2    Artigas, P.3    Reyes, N.4
  • 35
    • 0019995534 scopus 로고
    • Ouabain inhibits the increase due to palytoxin of cation permeability of erythrocytes
    • Habermann E, Chhatwal GS, 1982. Ouabain inhibits the increase due to palytoxin of cation permeability of erythrocytes. Naunyn-Schmiedeberg's Archives of Pharmacology 319 (2), 101–107.
    • (1982) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.319 , Issue.2 , pp. 101-107
    • Habermann, E.1    Chhatwal, G.S.2
  • 36
    • 0022551712 scopus 로고
    • Depolarization increases inositolphosphate production in a particulate preparation from rat brain
    • Habermann E, Laux M, 1986. Depolarization increases inositolphosphate production in a particulate preparation from rat brain. Naunyn-Schmiedeberg's Archives of Pharmacology 334 (1), 1–9.
    • (1986) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.334 , Issue.1 , pp. 1-9
    • Habermann, E.1    Laux, M.2
  • 37
    • 0024470756 scopus 로고
    • Palytoxin acts through Na+,K+-ATPase
    • Habermann E, 1989. Palytoxin acts through Na+,K+-ATPase. Toxicon 27 (11), 1171–1187.
    • (1989) Toxicon , vol.27 , Issue.11 , pp. 1171-1187
    • Habermann, E.1
  • 38
    • 0031081706 scopus 로고    scopus 로고
    • Palytoxin-induced single-channel currents from the sodium pump synthesized by in vitro expression
    • Hirsh JK, Wu CH, 1997. Palytoxin-induced single-channel currents from the sodium pump synthesized by in vitro expression. Toxicon 35 (2), 169–176.
    • (1997) Toxicon , vol.35 , Issue.2 , pp. 169-176
    • Hirsh, J.K.1    Wu, C.H.2
  • 40
    • 0032883243 scopus 로고    scopus 로고
    • Mechanisms underlying the hemolytic and ichthyotoxic activities of maitotoxin
    • Igarashi T, Aritake S, Yasumoto T, 1999. Mechanisms underlying the hemolytic and ichthyotoxic activities of maitotoxin. Natural Toxins 7, 71–79.
    • (1999) Natural Toxins , vol.7 , pp. 71-79
    • Igarashi, T.1    Aritake, S.2    Yasumoto, T.3
  • 41
    • 0023919542 scopus 로고
    • Palytoxin induces a nonselective cation channel in single ventricular cells of rat
    • Ikeda M, Mitani K, Ito K, 1988. Palytoxin induces a nonselective cation channel in single ventricular cells of rat. Naunyn-Schmiedeberg's Archives of Pharmacology 337 (5), 591–593.
    • (1988) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.337 , Issue.5 , pp. 591-593
    • Ikeda, M.1    Mitani, K.2    Ito, K.3
  • 42
    • 0032488926 scopus 로고    scopus 로고
    • Loss of cellular K+ mimics ribotoxic stress. Inhibition of protein synthesis and activation of the stress kinases SEK1/MKK4, stress-activated protein kinase/c-Jun NH2-terminal kinase 1, and p38/HOG1 by palytoxin
    • Iordanov MS, Magun BE, 1998. Loss of cellular K+ mimics ribotoxic stress. Inhibition of protein synthesis and activation of the stress kinases SEK1/MKK4, stress-activated protein kinase/c-Jun NH2-terminal kinase 1, and p38/HOG1 by palytoxin. The Journal of Biological Chemistry 273 (6), 3528–3534.
    • (1998) The Journal of Biological Chemistry , vol.273 , Issue.6 , pp. 3528-3534
    • Iordanov, M.S.1    Magun, B.E.2
  • 43
    • 0017726847 scopus 로고
    • The mode of contractile action of palytoxin on vascular smooth muscle
    • Ito K, Karaki H, Urakawa N, 1977. The mode of contractile action of palytoxin on vascular smooth muscle. European Journal of Pharmacology 46 (1), 9–14.
    • (1977) European Journal of Pharmacology , vol.46 , Issue.1 , pp. 9-14
    • Ito, K.1    Karaki, H.2    Urakawa, N.3
  • 44
    • 0030175344 scopus 로고    scopus 로고
    • Intestinal injuries caused by experimental playtoxicosis in mice
    • Ito E, Ohkusu M, Yasumoto T, 1996. Intestinal injuries caused by experimental playtoxicosis in mice. Toxicon 34 (6), 643–652.
    • (1996) Toxicon , vol.34 , Issue.6 , pp. 643-652
    • Ito, E.1    Ohkusu, M.2    Yasumoto, T.3
  • 45
    • 0030998806 scopus 로고    scopus 로고
    • Effects on repeated injections of palytoxin on lymphoid tissues in mice
    • Ito E, Okhusu M, Terao K, Yasumoto T, 1997. Effects on repeated injections of palytoxin on lymphoid tissues in mice. Toxicon 35 (5), 679–688.
    • (1997) Toxicon , vol.35 , Issue.5 , pp. 679-688
    • Ito, E.1    Okhusu, M.2    Terao, K.3    Yasumoto, T.4
  • 46
    • 67649390781 scopus 로고    scopus 로고
    • Toxicological studies on palytoxin and ostreocin-D administered to mice by three different routes
    • Ito E, Yasumoto T, 2009. Toxicological studies on palytoxin and ostreocin-D administered to mice by three different routes. Toxicon 54, 244–251.
    • (2009) Toxicon , vol.54 , pp. 244-251
    • Ito, E.1    Yasumoto, T.2
  • 48
    • 1842418882 scopus 로고    scopus 로고
    • Further guidance on derivation of the ARfD
    • Report of the JMPR 2002, FAO Plant Production and Protection Paper, 172,, FAO, Rome
    • JMPR (Joint FAO/WHO Meetings on Pesticide Residues), 2002 Further guidance on derivation of the ARfD. Pesticide residues in food-2002. Report of the JMPR 2002, FAO Plant Production and Protection Paper, 172, FAO, Rome, 4–8.
    • (2002) Pesticide residues in food-2002 , pp. 4-8
  • 49
    • 0023752761 scopus 로고
    • Palytoxin-induced contraction and release of endogenous noradrenaline in rat tail artery
    • Karaki H, Nagase H, Ohizumi Y, Satake N, Shibata S, 1988. Palytoxin-induced contraction and release of endogenous noradrenaline in rat tail artery. British Journal of Pharmacology 95 (1), 183–188.
    • (1988) British Journal of Pharmacology , vol.95 , Issue.1 , pp. 183-188
    • Karaki, H.1    Nagase, H.2    Ohizumi, Y.3    Satake, N.4    Shibata, S.5
  • 50
    • 84889405019 scopus 로고    scopus 로고
    • The chemistry of palytoxins and ostreocins
    • Botana LM, Hui YH, (Eds),, Blackwell Publishing, Iowa, USA
    • Katikou P, 2007. The chemistry of palytoxins and ostreocins. In: Phycotoxins: Chemistry and Biochemistry. Botana LM, Hui YH (Eds), Blackwell Publishing, Iowa, USA, 75–93.
    • (2007) Phycotoxins: Chemistry and Biochemistry , pp. 75-93
    • Katikou, P.1
  • 52
    • 0024421294 scopus 로고
    • Clinical and laboratory findings implicating palytoxin as cause of ciguatera poisoning due to Decapterus macrosoma (mackerel)
    • Kodama AM, Hokama Y, Yasumoto T, Fukui M, Manea SJ, Sutherland N, 1989. Clinical and laboratory findings implicating palytoxin as cause of ciguatera poisoning due to Decapterus macrosoma (mackerel). Toxicon 27(9), 1051–1053.
    • (1989) Toxicon , vol.27 , Issue.9 , pp. 1051-1053
    • Kodama, A.M.1    Hokama, Y.2    Yasumoto, T.3    Fukui, M.4    Manea, S.J.5    Sutherland, N.6
  • 53
    • 0029664514 scopus 로고    scopus 로고
    • Activation of stress-activator protein kinase/c-Jun N-terminal kinase by the non-TPA-type tumor promoter palytoxin
    • Kuroki DW, Bignami GS, Wattenberg EV, 1996. Activation of stress-activator protein kinase/c-Jun N-terminal kinase by the non-TPA-type tumor promoter palytoxin. Cancer Research 56 (3), 637–644.
    • (1996) Cancer Research , vol.56 , Issue.3 , pp. 637-644
    • Kuroki, D.W.1    Bignami, G.S.2    Wattenberg, E.V.3
  • 54
    • 0027378028 scopus 로고
    • Isolation of a novel fluorescent toxin from the coral reef crab, Lophozozymus pictor
    • Lau CO, Khoo HE, Yuen R, Wan M, Tan CH, 1993. Isolation of a novel fluorescent toxin from the coral reef crab, Lophozozymus pictor. Toxicon 31 (10), 1341–1345.
    • (1993) Toxicon , vol.31 , Issue.10 , pp. 1341-1345
    • Lau, C.O.1    Khoo, H.E.2    Yuen, R.3    Wan, M.4    Tan, C.H.5
  • 55
    • 0023219630 scopus 로고
    • Palytoxin: an extraordinarily potent stimulator of prostaglandin production and bone resorption in cultured mouse calvariae
    • Lazzaro M, Tashjian AH Jr., Fujiki H, Levine L, 1987. Palytoxin: an extraordinarily potent stimulator of prostaglandin production and bone resorption in cultured mouse calvariae. Endocrinology 120 (4), 1338–1345.
    • (1987) Endocrinology , vol.120 , Issue.4 , pp. 1338-1345
    • Lazzaro, M.1    Tashjian, A.H.2    Fujiki, H.3    Levine, L.4
  • 56
    • 58149484909 scopus 로고    scopus 로고
    • Suitability of the Neuro-2a cell line for the detection of palytoxin and analogues (neurotoxic phycotoxins)
    • Ledreux A, Krys S, Bernard C, 2009. Suitability of the Neuro-2a cell line for the detection of palytoxin and analogues (neurotoxic phycotoxins). Toxicon 53 (2), 300–308.
    • (2009) Toxicon , vol.53 , Issue.2 , pp. 300-308
    • Ledreux, A.1    Krys, S.2    Bernard, C.3
  • 57
    • 11144302536 scopus 로고    scopus 로고
    • First evidence of palytoxin analogues from an Ostreopsis mascarenensis (Dinophyceae) benthic bloom in Southwestern Indian Ocean
    • Lenoir S, Ten-Hage L, Turquet J, Quod JP, Bernard C, Hennion MC, 2004. First evidence of palytoxin analogues from an Ostreopsis mascarenensis (Dinophyceae) benthic bloom in Southwestern Indian Ocean. Journal of Phycology 40 (6), 1042–1051.
    • (2004) Journal of Phycology , vol.40 , Issue.6 , pp. 1042-1051
    • Lenoir, S.1    Ten-Hage, L.2    Turquet, J.3    Quod, J.P.4    Bernard, C.5    Hennion, M.C.6
  • 58
    • 0022218969 scopus 로고
    • Stimulation of arachidonic-acid metabolism by different types of tumor promoters
    • Levine L, Fujiki H, 1985. Stimulation of arachidonic-acid metabolism by different types of tumor promoters. Carcinogenesis 6 (11), 1631–1634.
    • (1985) Carcinogenesis , vol.6 , Issue.11 , pp. 1631-1634
    • Levine, L.1    Fujiki, H.2
  • 60
    • 0032135775 scopus 로고    scopus 로고
    • Differential activation of mitogen-activated protein kinases by palytoxin and ouabain, two ligands for the Na+,K+-ATPase
    • Li S, Wattenberg EV, 1998. Differential activation of mitogen-activated protein kinases by palytoxin and ouabain, two ligands for the Na+,K+-ATPase. Toxicology and Applied Pharmacology 151 (2), 377–384.
    • (1998) Toxicology and Applied Pharmacology , vol.151 , Issue.2 , pp. 377-384
    • Li, S.1    Wattenberg, E.V.2
  • 61
    • 0032732969 scopus 로고    scopus 로고
    • Cell-type-specific activation of p38 protein kinase cascades by the novel tumor promoter palytoxin
    • Li S, Wattenberg EV, 1999. Cell-type-specific activation of p38 protein kinase cascades by the novel tumor promoter palytoxin. Toxicology and Applied Pharmacology 160 (2), 109–119.
    • (1999) Toxicology and Applied Pharmacology , vol.160 , Issue.2 , pp. 109-119
    • Li, S.1    Wattenberg, E.V.2
  • 63
    • 29544441533 scopus 로고    scopus 로고
    • Enhancement of transformed foci and induction of prostaglandins in Balb/c 3T3 cells by palytoxin: in vitro model reproduces carcinogenic responses in animal models regarding the inhibitory effect of indomethacin and reversal of indomethacin's effect by exogenous prostaglandins
    • Miura D, Kobayashi M, Kakiuchi S, Kasahara Y, Kondo S, 2006. Enhancement of transformed foci and induction of prostaglandins in Balb/c 3T3 cells by palytoxin: in vitro model reproduces carcinogenic responses in animal models regarding the inhibitory effect of indomethacin and reversal of indomethacin's effect by exogenous prostaglandins. Toxicological Sciences 89 (1), 154–163.
    • (2006) Toxicological Sciences , vol.89 , Issue.1 , pp. 154-163
    • Miura, D.1    Kobayashi, M.2    Kakiuchi, S.3    Kasahara, Y.4    Kondo, S.5
  • 64
    • 0029899051 scopus 로고    scopus 로고
    • Palytoxin modulates cytosolic pH in human osteoblast-like Saos-2 cells via an interaction with Na(+)-K(+)-ATPase
    • Pt 1)
    • Monroe JJ, Tashjian AH Jr, 1996. Palytoxin modulates cytosolic pH in human osteoblast-like Saos-2 cells via an interaction with Na(+)-K(+)-ATPase. The American Journal of Physiology 270 (5 Pt 1), C1277–1283.
    • (1996) The American Journal of Physiology , vol.270 , Issue.5 , pp. C1277-1283
    • Monroe, J.J.1    Tashjian, A.H.2
  • 66
    • 33749587971 scopus 로고    scopus 로고
    • Toxicological requirements for risk assessment of shellfish contaminants: a review
    • Munday R, 2006. Toxicological requirements for risk assessment of shellfish contaminants: a review. African Journal of Marine Science 28 (2), 447–449.
    • (2006) African Journal of Marine Science , vol.28 , Issue.2 , pp. 447-449
    • Munday, R.1
  • 67
    • 84919880901 scopus 로고    scopus 로고
    • Occurrence and Toxicology of Palytoxins
    • Botana LM, (Ed.), 2nd edition, ed., Boca Raton, FL, CRC Press (Taylor and Francys Group)
    • Munday R, 2008. Occurrence and Toxicology of Palytoxins. In: Seafood and Freshwater toxins: Pharmacology, Physiology and Detection. Botana LM (Ed.) 2nd edition ed. Boca Raton, FL: CRC Press (Taylor and Francys Group), 693–713.
    • (2008) Seafood and Freshwater toxins: Pharmacology, Physiology and Detection , pp. 693-713
    • Munday, R.1
  • 69
    • 0023875038 scopus 로고
    • Single ionic channels induced by palytoxin in guinea-pig ventricular myocytes
    • Muramatsu I, Nishio M, Kigoshi S and Uemura D, 1988. Single ionic channels induced by palytoxin in guinea-pig ventricular myocytes. British Journal of Pharmacology 93 (4), 811–816.
    • (1988) British Journal of Pharmacology , vol.93 , Issue.4 , pp. 811-816
    • Muramatsu, I.1    Nishio, M.2    Kigoshi, S.3    Uemura, D.4
  • 70
    • 0023635135 scopus 로고
    • Palytoxin-induced contraction and release of prostaglandins and norepinephrine in the aorta
    • Nagase H, Karaki H, 1987. Palytoxin-induced contraction and release of prostaglandins and norepinephrine in the aorta. Journal of Pharmacology and Experimental Therapeutics 242 (3), 1120–1125.
    • (1987) Journal of Pharmacology and Experimental Therapeutics , vol.242 , Issue.3 , pp. 1120-1125
    • Nagase, H.1    Karaki, H.2
  • 71
    • 33748136407 scopus 로고    scopus 로고
    • A modified assay to determine hemolytic toxin variability among Karenia clones isolated from the Gulf of Mexico
    • Neely T, Campbell L, 2006. A modified assay to determine hemolytic toxin variability among Karenia clones isolated from the Gulf of Mexico. Harmful Algae 5, 592–598.
    • (2006) Harmful Algae , vol.5 , pp. 592-598
    • Neely, T.1    Campbell, L.2
  • 73
    • 0034839850 scopus 로고    scopus 로고
    • Hemolytic activity of Heterocapsa circularisquama (Dinophyceae) and its possible involvement in shellfish toxicity
    • Oda T, Sato Y, Kim D, Muramatsu T, Matsuyama Y, Honjo T, 2001. Hemolytic activity of Heterocapsa circularisquama (Dinophyceae) and its possible involvement in shellfish toxicity. Journal of Phycology 37, 509–516.
    • (2001) Journal of Phycology , vol.37 , pp. 509-516
    • Oda, T.1    Sato, Y.2    Kim, D.3    Muramatsu, T.4    Matsuyama, Y.5    Honjo, T.6
  • 75
    • 1242292341 scopus 로고    scopus 로고
    • Identification of palytoxin as a principle which causes morphological changes in rat 3Y1 cells in the zoanthid Palythoa aff. margaritae
    • Oku N, Sata NU, Matsunaga S, Uchida H, Fusetani N, 2004. Identification of palytoxin as a principle which causes morphological changes in rat 3Y1 cells in the zoanthid Palythoa aff. margaritae. Toxicon 43 (1), 21–25.
    • (2004) Toxicon , vol.43 , Issue.1 , pp. 21-25
    • Oku, N.1    Sata, N.U.2    Matsunaga, S.3    Uchida, H.4    Fusetani, N.5
  • 77
    • 0029153948 scopus 로고
    • Isolation and chemical –structure of amphidinol-2, a potent haemolytic compound from the marine dinoflagellate Amphidinium klebsii
    • Paul GK, Matsumori N, Murata M, Tachibana K, 1995. Isolation and chemical –structure of amphidinol-2, a potent haemolytic compound from the marine dinoflagellate Amphidinium klebsii. Tetrahedron Letters 36, 6279–6282.
    • (1995) Tetrahedron Letters , vol.36 , pp. 6279-6282
    • Paul, G.K.1    Matsumori, N.2    Murata, M.3    Tachibana, K.4
  • 78
    • 13944275652 scopus 로고    scopus 로고
    • Characterization of Ostreopsis and Coolia (Dinophyceae) isolates in the western Mediterranean Sea based on morphology, toxicity and internal transcribed spacer 5.8s rDNA sequences
    • Penna A, Vila M, Fraga S, Giacobbe MG, Andreoni F, Riobó P, Vernesi C, 2005. Characterization of Ostreopsis and Coolia (Dinophyceae) isolates in the western Mediterranean Sea based on morphology, toxicity and internal transcribed spacer 5.8s rDNA sequences. Journal of Phycology 41 (1), 212–225.
    • (2005) Journal of Phycology , vol.41 , Issue.1 , pp. 212-225
    • Penna, A.1    Vila, M.2    Fraga, S.3    Giacobbe, M.G.4    Andreoni, F.5    Riobó, P.6    Vernesi, C.7
  • 80
    • 0030070890 scopus 로고    scopus 로고
    • Palytoxin-induced Na+ influx into yeast cells expressing the mammalian sodium pump is due to the formation of a channel within the enzyme
    • Redondo J, Fiedler B, Scheiner-Bobis G, 1996. Palytoxin-induced Na+ influx into yeast cells expressing the mammalian sodium pump is due to the formation of a channel within the enzyme. Molecular Pharmacology 49 (1), 49–57.
    • (1996) Molecular Pharmacology , vol.49 , Issue.1 , pp. 49-57
    • Redondo, J.1    Fiedler, B.2    Scheiner-Bobis, G.3
  • 81
    • 33749169688 scopus 로고    scopus 로고
    • Ion permeation through the Na+,K+-ATPase
    • Reyes N, Gadsby DC, 2006. Ion permeation through the Na+,K+-ATPase. Nature 443 (7110), 470–474.
    • (2006) Nature , vol.443 , Issue.7110 , pp. 470-474
    • Reyes, N.1    Gadsby, D.C.2
  • 83
    • 85078375315 scopus 로고    scopus 로고
    • In Proceedings of the 20th Marine Biotoxin Science Workshop,, Wellington New Zealand, New Zealand Food Safety Authorities
    • Rhodes LL, Munday R, 2004. Palytoxins: a risk to human health? In: Proceedings of the 20th Marine Biotoxin Science Workshop, Wellington New Zealand, New Zealand Food Safety Authorities, vol. 23.
    • (2004) Palytoxins: a risk to human health? , vol.23
    • Rhodes, L.L.1    Munday, R.2
  • 84
    • 33748034413 scopus 로고    scopus 로고
    • Analysis of palytoxin-like in Ostreopsis cultures by liquid chromatography with precolumn derivatization and fluorescence detection
    • Riobó P, Paz B, Franco JM, 2006. Analysis of palytoxin-like in Ostreopsis cultures by liquid chromatography with precolumn derivatization and fluorescence detection. Analytica Chimica Acta 566 (2), 217–223.
    • (2006) Analytica Chimica Acta , vol.566 , Issue.2 , pp. 217-223
    • Riobó, P.1    Paz, B.2    Franco, J.M.3
  • 85
    • 47349110636 scopus 로고    scopus 로고
    • Mouse bioassay for palytoxin. Specific symptoms and dose-response against dose-death time relationships
    • Riobó P, Paz B, Franco JM, Vazquez JA, Murado MA, Cacho E, 2008. Mouse bioassay for palytoxin. Specific symptoms and dose-response against dose-death time relationships. Food and Chemical Toxicology 46 (8), 2639–2647.
    • (2008) Food and Chemical Toxicology , vol.46 , Issue.8 , pp. 2639-2647
    • Riobó, P.1    Paz, B.2    Franco, J.M.3    Vazquez, J.A.4    Murado, M.A.5    Cacho, E.6
  • 86
    • 0024452923 scopus 로고
    • Effect of palytoxin on the calcium current and the mechanical activity of frog heart muscle
    • Sauviat MP, 1989. Effect of palytoxin on the calcium current and the mechanical activity of frog heart muscle. British Journal of Pharmacology 98 (3), 773–780.
    • (1989) British Journal of Pharmacology , vol.98 , Issue.3 , pp. 773-780
    • Sauviat, M.P.1
  • 90
    • 56749163392 scopus 로고    scopus 로고
    • The ion pathway through the opened Na(+), K(+)-ATPase pump
    • Takeuchi A, Reyes N, Artigas P, Gadsby DC, 2008. The ion pathway through the opened Na(+), K(+)-ATPase pump. Nature 456 (7220), 413–416.
    • (2008) Nature , vol.456 , Issue.7220 , pp. 413-416
    • Takeuchi, A.1    Reyes, N.2    Artigas, P.3    Gadsby, D.C.4
  • 91
  • 92
  • 93
    • 0027025020 scopus 로고
    • Light and electron microscopic observation of experimental palytoxin poisoning in mice
    • Terao K, Ito E, Yasumoto T, 1992. Light and electron microscopic observation of experimental palytoxin poisoning in mice. Bulletin de la Societe de Pathologie Exotique 85, 494–496.
    • (1992) Bulletin de la Societe de Pathologie Exotique , vol.85 , pp. 494-496
    • Terao, K.1    Ito, E.2    Yasumoto, T.3
  • 94
    • 0043211785 scopus 로고    scopus 로고
    • Mechanism of action, pharmacology and toxicology
    • Botana LM, (Ed),, Marcel Dekker, New York, USA
    • Tosteson MT, 2000. Mechanism of action, pharmacology and toxicology. In: Seafood and Freshwater Toxins. Botana LM (Ed), Marcel Dekker, New York, USA, 549–566.
    • (2000) Seafood and Freshwater Toxins , pp. 549-566
    • Tosteson, M.T.1
  • 95
    • 33846225692 scopus 로고    scopus 로고
    • Bioorganic studies on marine natural products-diverse chemical structures and bioactivities
    • Uemura D, 2006. Bioorganic studies on marine natural products-diverse chemical structures and bioactivities. The Chemical Record 6 (5), 235–248.
    • (2006) The Chemical Record , vol.6 , Issue.5 , pp. 235-248
    • Uemura, D.1
  • 99
    • 33744913282 scopus 로고    scopus 로고
    • Modulation of calcium entry and glutamate release in cultured cerebellar granule cells by palytoxin
    • Vale C, Alfonso A, Sunol C, Vieytes MR, Botana LM, 2006. Modulation of calcium entry and glutamate release in cultured cerebellar granule cells by palytoxin. Journal of Neuroscience Research 83 (8), 1393–1406.
    • (2006) Journal of Neuroscience Research , vol.83 , Issue.8 , pp. 1393-1406
    • Vale, C.1    Alfonso, A.2    Sunol, C.3    Vieytes, M.R.4    Botana, L.M.5
  • 100
    • 33846277239 scopus 로고    scopus 로고
    • Palytoxin: exploiting a novel skin tumor promoter to explore signal transduction and carcinogenesis
    • Wattenberg EV, 2007. Palytoxin: exploiting a novel skin tumor promoter to explore signal transduction and carcinogenesis. American Journal of Physiology-Cell Physiology 292, C24–C32.
    • (2007) American Journal of Physiology-Cell Physiology , vol.292 , pp. C24-C32
    • Wattenberg, E.V.1
  • 101
    • 0016590780 scopus 로고
    • The mechanism of action and treatment of palytoxin poisoning
    • Vick JA, Wiles JS, 1975. The mechanism of action and treatment of palytoxin poisoning. Toxicology and Applied Pharmacology 34 (2), 214–223.
    • (1975) Toxicology and Applied Pharmacology , vol.34 , Issue.2 , pp. 214-223
    • Vick, J.A.1    Wiles, J.S.2
  • 103
    • 0016171571 scopus 로고
    • Toxicological evaluation of palytoxin in several animal species
    • Wiles JS, Vick JA, Christensen MK, 1974. Toxicological evaluation of palytoxin in several animal species. Toxicon 12 (4), 427–433.
    • (1974) Toxicon , vol.12 , Issue.4 , pp. 427-433
    • Wiles, J.S.1    Vick, J.A.2    Christensen, M.K.3
  • 107
    • 0025827226 scopus 로고
    • Mechanism of palytoxin-induced Na+ influx into cultured bovine adrenal chromaffin cells: possible involvement of Na+/H+ exchange system
    • Yoshizumi M, Houchi H, Ishimura Y, Masuda Y, Morita K, Oka M, 1991. Mechanism of palytoxin-induced Na+ influx into cultured bovine adrenal chromaffin cells: possible involvement of Na+/H+ exchange system. Neuroscience Letters 130, 103–106.
    • (1991) Neuroscience Letters , vol.130 , pp. 103-106
    • Yoshizumi, M.1    Houchi, H.2    Ishimura, Y.3    Masuda, Y.4    Morita, K.5    Oka, M.6
  • 108
    • 0142219793 scopus 로고    scopus 로고
    • Mitogen activated protein kinases selectively regulate palytoxin-stimulated gene expression in mouse keratinocytes
    • Zeliadt NA, Warmka JK, Wattenberg EV, 2003. Mitogen activated protein kinases selectively regulate palytoxin-stimulated gene expression in mouse keratinocytes. Toxicology and Applied Pharmacology 192 (3), 212–221.
    • (2003) Toxicology and Applied Pharmacology , vol.192 , Issue.3 , pp. 212-221
    • Zeliadt, N.A.1    Warmka, J.K.2    Wattenberg, E.V.3


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