Neutralization of interleukin-17 suppresses allergic rhinitis symptoms by downregulating Th2 and Th17 responses and upregulating the Treg response

Oncotarget

Volumn 8, Issue 14, 2017, Pages 22361-22369

  Gu, Zhao Wei ^a   Wang, Yun Xiu ^a   Cao, Zhi Wei ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Allergic rhinitis; Immune response; Immunity; Immunology and Microbiology Section; Interleukin 17; Neutralization; Th17; Th2

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 17; INTERLEUKIN 17 ANTIBODY; NEUTRALIZING ANTIBODY; STAT3 PROTEIN; STAT5 PROTEIN;

ALLERGIC RHINITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; CELLULAR DISTRIBUTION; CELLULAR IMMUNITY; CELLULAR PARAMETERS; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; EOSINOPHIL COUNT; FEASIBILITY STUDY; FEMALE; IMMUNOPATHOGENESIS; IMMUNOREGULATION; MOUSE; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NONHUMAN; NOSE MUCOSA; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; SNEEZING; SYMPTOM; TH1 CELL; TH17 CELL; TH2 CELL; TREATMENT RESPONSE; UPREGULATION; ANIMAL; CELL CULTURE; CELL MOTION; DISEASE MODEL; DRUG EFFECTS; EOSINOPHIL; HUMAN; IMMUNOLOGY; IMMUNOTHERAPY; METABOLISM; NEUTROPHIL; PROCEDURES; RHINITIS, ALLERGIC; SIGNAL TRANSDUCTION; TH1 TH2 BALANCE;

ANIMALS; ANTIBODIES, NEUTRALIZING; CELL MOVEMENT; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EOSINOPHILS; FEMALE; HUMANS; IMMUNOTHERAPY; INTERLEUKIN-17; MICE; MICE, INBRED BALB C; NEUTROPHILS; RHINITIS, ALLERGIC; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STAT5 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, REGULATORY; TH1-TH2 BALANCE; TH17 CELLS; TH2 CELLS;

EID: 85017034312     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.15652     Document Type: Article

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