Plerixafor and G-CSF combination mobilizes hematopoietic stem and progenitors cells with a distinct transcriptional profile and a reduced in vivo homing capacity compared to plerixafor alone

Haematologica

Volumn 102, Issue 4, 2017, Pages e120-e124

  Lidonnici, Maria Rosa ^a,b   Aprile, Annamaria ^a,c   Frittoli, Marta Claudia ^d   Mandelli, Giacomo ^a   Paleari, Ylenia ^a,b   Spinelli, Antonello ^d   Gentner, Bernhard ^d   Zambelli, Matilde ^d   Parisi, Cristina ^d   Bellio, Laura ^d   Cassinerio, Elena ^e   Zanaboni, Laura ^e   Cappellini, Maria Domenica ^e   Ciceri, Fabio ^d   Marktel, Sarah ^d   Ferrari, Giuliana ^a,b  

^a SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d SAN RAFFAELE HOSPITAL   (Italy)

^e UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; CELL CYCLE PROTEIN 6; CHECKPOINT KINASE 1; CHEMOKINE RECEPTOR CXCR4; GRANULOCYTE COLONY STIMULATING FACTOR; PLERIXAFOR; PROTEIN KINASE; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTION FACTOR; CD34 ANTIGEN; CELL CYCLE PROTEIN; CXCL12 PROTEIN, HUMAN; CXCR4 PROTEIN, HUMAN; ENDONUCLEASE; HETEROCYCLIC COMPOUND; PROTEIN BINDING;

CD34 SELECTION; CELL HOMING; CELL PROLIFERATION; DNA TRANSCRIPTION; DOWN REGULATION; GENE; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNOPHENOTYPING; INTRACELLULAR SIGNALING; LETTER; META ANALYSIS (TOPIC); NONHUMAN; STEM CELL MOBILIZATION; UPREGULATION; ANIMAL; BETA THALASSEMIA; CYTOLOGY; DRUG COMBINATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNOLOGY; LEUKAPHERESIS; MESENCHYMAL STROMA CELL; MOUSE; PATHOLOGY; PROCEDURES; SIGNAL TRANSDUCTION; STEM CELL NICHE;

ANIMALS; ANTIGENS, CD34; BETA-THALASSEMIA; CELL CYCLE PROTEINS; CHEMOKINE CXCL12; DRUG COMBINATIONS; ENDONUCLEASES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HETEROCYCLIC COMPOUNDS; HUMANS; IMMUNOPHENOTYPING; LEUKAPHERESIS; MESENCHYMAL STROMAL CELLS; MICE; PROTEIN BINDING; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION; STEM CELL NICHE;

EID: 85017001668     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2016.154740     Document Type: Letter

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