메뉴 건너뛰기




Volumn 19, Issue 5, 2017, Pages

Cardiac Complications of Cancer Therapy: Pathophysiology, Identification, Prevention, Treatment, and Future Directions

Author keywords

Anthracyclines; Checkpoint inhibitors; Congestive heart failure; Doxorubicin; Radionuclide ventriculography; Trastuzumab

Indexed keywords

BEVACIZUMAB; BORTEZOMIB; BUSULFAN; CAPECITABINE; CARFILZOMIB; CISPLATIN; CYCLOPHOSPHAMIDE; CYTARABINE; DASATINIB; DAUNORUBICIN; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; FLUDARABINE; FLUOROURACIL; IDARUBICIN; IFOSFAMIDE; IMATINIB; METHOTREXATE; MITOMYCIN; MITOXANTRONE; PACLITAXEL; PERTUZUMAB; SUNITINIB; TENIPOSIDE; TRASTUZUMAB; UNINDEXED DRUG; VINBLASTINE; VINCRISTINE; ANTHRACYCLINE; ANTINEOPLASTIC AGENT;

EID: 85016931320     PISSN: 15233782     EISSN: 15343170     Source Type: Journal    
DOI: 10.1007/s11886-017-0846-x     Document Type: Review
Times cited : (75)

References (86)
  • 1
    • 84954400636 scopus 로고    scopus 로고
    • Cancer statistics 2016
    • PID: 26742998, An important resource for current cancer statistics
    • • Siegel RL, Miller KD, Jemal A. Cancer statistics 2016. CA Cancer J Clin. 2016;66:7–30. An important resource for current cancer statistics
    • (2016) CA Cancer J Clin , vol.66 , pp. 7-30
    • Siegel, R.L.1    Miller, K.D.2    Jemal, A.3
  • 2
    • 77954582454 scopus 로고    scopus 로고
    • Long-term cause-specific mortality among survivors of childhood cancer
    • COI: 1:CAS:528:DC%2BC3cXovFSqtrw%3D, PID: 20628130
    • Reulen RC, Winter DL, Frobisher C, et al. Long-term cause-specific mortality among survivors of childhood cancer. JAMA. 2010;304:172–9.
    • (2010) JAMA , vol.304 , pp. 172-179
    • Reulen, R.C.1    Winter, D.L.2    Frobisher, C.3
  • 3
    • 84886021050 scopus 로고    scopus 로고
    • Long-term cardiovascular toxicity in children, adolescents, and young adults who receive cancer therapy: pathophysiology, course, monitoring, management, prevention, and research directions: a scientific statement from the American Heart Association
    • PID: 24081971
    • Lipshultz SE, Adams MJ, Colan SD, et al. Long-term cardiovascular toxicity in children, adolescents, and young adults who receive cancer therapy: pathophysiology, course, monitoring, management, prevention, and research directions: a scientific statement from the American Heart Association. Circulation. 2013;128:1927–95.
    • (2013) Circulation , vol.128 , pp. 1927-1995
    • Lipshultz, S.E.1    Adams, M.J.2    Colan, S.D.3
  • 4
    • 74049097142 scopus 로고    scopus 로고
    • Cardiotoxicity of anticancer drugs: the need for cardio-oncology and cardio-oncological prevention
    • COI: 1:CAS:528:DC%2BC3cXkt1Cksg%3D%3D, PID: 20007921
    • Albini A, Pennesi G, Donatelli F, et al. Cardiotoxicity of anticancer drugs: the need for cardio-oncology and cardio-oncological prevention. J Natl Cancer Inst. 2010;102:14–25.
    • (2010) J Natl Cancer Inst , vol.102 , pp. 14-25
    • Albini, A.1    Pennesi, G.2    Donatelli, F.3
  • 5
    • 84878013653 scopus 로고    scopus 로고
    • Traditional and novel methods to assess and prevent chemotherapy-related cardiac dysfunction noninvasively
    • PID: 23572315
    • Schwartz RG, Jain D, Storozynsky E. Traditional and novel methods to assess and prevent chemotherapy-related cardiac dysfunction noninvasively. J Nucl Cardiol. 2013;20:443–64.
    • (2013) J Nucl Cardiol , vol.20 , pp. 443-464
    • Schwartz, R.G.1    Jain, D.2    Storozynsky, E.3
  • 6
    • 84973131628 scopus 로고    scopus 로고
    • The role and clinical effectiveness of multimodality imaging in the management of cardiac complications of cancer and cancer therapy
    • PID: 27251147, An important comprehensive recent article on cardiovascula issues in cancer patients
    • •• Russell RR, Alexander J, Jain D, et al. The role and clinical effectiveness of multimodality imaging in the management of cardiac complications of cancer and cancer therapy. J Nucl Cardiol. 2016;23:856–84. doi:10.1007/s12350-016-0538-8. An important comprehensive recent article on cardiovascula issues in cancer patients
    • (2016) J Nucl Cardiol , vol.23 , pp. 856-884
    • Russell, R.R.1    Alexander, J.2    Jain, D.3
  • 7
    • 6044274062 scopus 로고    scopus 로고
    • Cardiovascular complications of cancer therapy: diagnosis, pathogenesis, and management
    • PID: 15226229
    • Yeh ETH, Tong AT, Lenihan DJ, et al. Cardiovascular complications of cancer therapy: diagnosis, pathogenesis, and management. Circulation. 2004;109:3122–31.
    • (2004) Circulation , vol.109 , pp. 3122-3131
    • Yeh, E.T.H.1    Tong, A.T.2    Lenihan, D.J.3
  • 8
    • 84861325625 scopus 로고    scopus 로고
    • Anthracycline cardiotoxicity: prevalence, pathogenesis and treatment
    • COI: 1:CAS:528:DC%2BC38Xmt12qsrc%3D, PID: 22758622
    • Volkova M, Russell R. Anthracycline cardiotoxicity: prevalence, pathogenesis and treatment. Curr Cardiol Rev. 2011;7:214–20.
    • (2011) Curr Cardiol Rev , vol.7 , pp. 214-220
    • Volkova, M.1    Russell, R.2
  • 9
    • 0018123277 scopus 로고
    • Early anthracycline cardiotoxicity
    • COI: 1:STN:280:DyaE1M%2FjvFelsQ%3D%3D, PID: 707541
    • Bristow MR, Thompson PD, Martin RP, et al. Early anthracycline cardiotoxicity. Am J Med. 1978;65:823–32.
    • (1978) Am J Med , vol.65 , pp. 823-832
    • Bristow, M.R.1    Thompson, P.D.2    Martin, R.P.3
  • 10
    • 84935443652 scopus 로고    scopus 로고
    • Early detection of anthracycline cardiotoxicity and improvement with heart failure therapy
    • COI: 1:CAS:528:DC%2BC2MXpt1WrtLo%3D, PID: 25948538
    • Cardinale D, Colombo A, Bacchiani G, et al. Early detection of anthracycline cardiotoxicity and improvement with heart failure therapy. Circulation. 2015;131:1981–8.
    • (2015) Circulation , vol.131 , pp. 1981-1988
    • Cardinale, D.1    Colombo, A.2    Bacchiani, G.3
  • 11
    • 23044447053 scopus 로고    scopus 로고
    • Molecular pharmacology of the interaction of anthracyclines with iron
    • COI: 1:CAS:528:DC%2BD2MXntVSgu7g%3D, PID: 15883202
    • Xu X, Persson HL, Richardson DR. Molecular pharmacology of the interaction of anthracyclines with iron. Mol Pharmacol. 2005;68:261–71.
    • (2005) Mol Pharmacol , vol.68 , pp. 261-271
    • Xu, X.1    Persson, H.L.2    Richardson, D.R.3
  • 12
    • 84869209094 scopus 로고    scopus 로고
    • Identification of the molecular basis of doxorubicin-induced cardiotoxicity
    • PID: 23104132
    • Zhang S, Liu X, Bawa-Khalfe T, et al. Identification of the molecular basis of doxorubicin-induced cardiotoxicity. Nat Med. 2012;18:1639–42.
    • (2012) Nat Med , vol.18 , pp. 1639-1642
    • Zhang, S.1    Liu, X.2    Bawa-Khalfe, T.3
  • 13
    • 0038521374 scopus 로고    scopus 로고
    • Congestive heart failure in patients treated with doxorubicin
    • COI: 1:CAS:528:DC%2BD3sXkslWrsLs%3D, PID: 12767102
    • Swain SM, Whaley FS, Ewer MS. Congestive heart failure in patients treated with doxorubicin. Cancer. 2003;97:2869–79.
    • (2003) Cancer , vol.97 , pp. 2869-2879
    • Swain, S.M.1    Whaley, F.S.2    Ewer, M.S.3
  • 14
    • 34250787016 scopus 로고    scopus 로고
    • Potentiation of doxorubicin cardiotoxicity by iron loading in a rodent model
    • COI: 1:CAS:528:DC%2BD2sXntFyhs7o%3D, PID: 17599610
    • Panjrath GS, Patel V, Valdiviezo CI, et al. Potentiation of doxorubicin cardiotoxicity by iron loading in a rodent model. J Am Coll Cardiol. 2007;49:2457–64.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 2457-2464
    • Panjrath, G.S.1    Patel, V.2    Valdiviezo, C.I.3
  • 15
    • 0034909855 scopus 로고    scopus 로고
    • Anthracycline-induced acute cardiotoxicity in adults treated for leukaemia. Analysis of the clinico-pathological aspects of documented acute anthracycline-induced cardiotoxicity in patients treated for acute leukaemia at the University Hospital of Zurich, Switzerland, between 1990 and 1996
    • COI: 1:STN:280:DC%2BD3MvnvVehtw%3D%3D, PID: 11521803
    • Dazzi H, Kaufmann K, Follath F. Anthracycline-induced acute cardiotoxicity in adults treated for leukaemia. Analysis of the clinico-pathological aspects of documented acute anthracycline-induced cardiotoxicity in patients treated for acute leukaemia at the University Hospital of Zurich, Switzerland, between 1990 and 1996. Ann Oncol. 2001;12:963–6.
    • (2001) Ann Oncol , vol.12 , pp. 963-966
    • Dazzi, H.1    Kaufmann, K.2    Follath, F.3
  • 16
    • 0026031848 scopus 로고
    • Late cardiac effects of doxorubicin therapy for acute lymphoblastic leukemia in childhood
    • COI: 1:STN:280:DyaK3M7kvVKksQ%3D%3D, PID: 1997853
    • Lipshultz SE, Colan SD, Gelber RD, et al. Late cardiac effects of doxorubicin therapy for acute lymphoblastic leukemia in childhood. N Engl J Med. 1991;324:808–15.
    • (1991) N Engl J Med , vol.324 , pp. 808-815
    • Lipshultz, S.E.1    Colan, S.D.2    Gelber, R.D.3
  • 17
    • 18444416815 scopus 로고    scopus 로고
    • Chronic progressive cardiac dysfunction years after doxorubicin therapy for childhood acute lymphoblastic leukemia
    • COI: 1:CAS:528:DC%2BD2MXktleqtr4%3D, PID: 15837978
    • Lipshultz SE, Lipsitz SR, Sallan SE, et al. Chronic progressive cardiac dysfunction years after doxorubicin therapy for childhood acute lymphoblastic leukemia. J Clin Oncol. 2005;23:2629–36.
    • (2005) J Clin Oncol , vol.23 , pp. 2629-2636
    • Lipshultz, S.E.1    Lipsitz, S.R.2    Sallan, S.E.3
  • 18
    • 0018716636 scopus 로고
    • Risk factors for doxorubicin-induced congestive heart failure
    • COI: 1:STN:280:DyaL3c%2FktVGqtw%3D%3D, PID: 496103
    • Von Hoff DD, Layard MW, Basa P, et al. Risk factors for doxorubicin-induced congestive heart failure. Ann Intern Med. 1979;91:710–7.
    • (1979) Ann Intern Med , vol.91 , pp. 710-717
    • Von Hoff, D.D.1    Layard, M.W.2    Basa, P.3
  • 19
    • 0141816698 scopus 로고    scopus 로고
    • Hfe deficiency increases susceptibility to cardiotoxicity and exacerbates changes in iron metabolism induced by doxorubicin
    • COI: 1:CAS:528:DC%2BD3sXnslykur0%3D, PID: 12805055
    • Miranda CJ, Makui H, Soares RJ, et al. Hfe deficiency increases susceptibility to cardiotoxicity and exacerbates changes in iron metabolism induced by doxorubicin. Blood. 2003;102:2574–80.
    • (2003) Blood , vol.102 , pp. 2574-2580
    • Miranda, C.J.1    Makui, H.2    Soares, R.J.3
  • 20
    • 0018757883 scopus 로고
    • Serial assessment of doxorubicin cardiotoxicity with quantitative radionuclide angiocardiography
    • COI: 1:STN:280:DyaE1M%2Fptlymtw%3D%3D, PID: 759880
    • Alexander J, Dainiak N, Berger HJ, et al. Serial assessment of doxorubicin cardiotoxicity with quantitative radionuclide angiocardiography. N Engl J Med. 1979;300:278–83.
    • (1979) N Engl J Med , vol.300 , pp. 278-283
    • Alexander, J.1    Dainiak, N.2    Berger, H.J.3
  • 21
    • 0020591843 scopus 로고
    • Serial radionuclide assessment of doxorubicin cardiotoxicity in cancer patients with abnormal baseline resting left ventricular performance
    • COI: 1:STN:280:DyaL3szgsFCntA%3D%3D, PID: 6613807
    • Choi BW, Berger HJ, Schwartz PE, et al. Serial radionuclide assessment of doxorubicin cardiotoxicity in cancer patients with abnormal baseline resting left ventricular performance. Am Heart J. 1983;106:638–43.
    • (1983) Am Heart J , vol.106 , pp. 638-643
    • Choi, B.W.1    Berger, H.J.2    Schwartz, P.E.3
  • 22
    • 0037368303 scopus 로고    scopus 로고
    • Doxorubicin cardiotoxicity: prevention of congestive heart failure with serial cardiac function monitoring with equilibrium radionuclide angiocardiography in the current era
    • PID: 12673177
    • Mitani I, Jain D, Joska TM, Burtness B, Zaret BL. Doxorubicin cardiotoxicity: prevention of congestive heart failure with serial cardiac function monitoring with equilibrium radionuclide angiocardiography in the current era. J Nucl Cardiol. 2003;10:132–9.
    • (2003) J Nucl Cardiol , vol.10 , pp. 132-139
    • Mitani, I.1    Jain, D.2    Joska, T.M.3    Burtness, B.4    Zaret, B.L.5
  • 23
    • 0023634395 scopus 로고
    • Congestive heart failure and left ventricular dysfunction complicating doxorubicin therapy: seven-year experience using serial radionuclide angiocardiography
    • COI: 1:STN:280:DyaL2s3mslKlsQ%3D%3D, PID: 3605130
    • Schwartz RG, McKenzie WB, Alexander J, et al. Congestive heart failure and left ventricular dysfunction complicating doxorubicin therapy: seven-year experience using serial radionuclide angiocardiography. Am J Med. 1987;82:1109–18.
    • (1987) Am J Med , vol.82 , pp. 1109-1118
    • Schwartz, R.G.1    McKenzie, W.B.2    Alexander, J.3
  • 24
    • 34548522479 scopus 로고    scopus 로고
    • American Society of Clinical Oncology clinical evidence review on the ongoing care of adult cancer survivors: cardiac and pulmonary late effects
    • COI: 1:CAS:528:DC%2BD2sXhtFanu73F, PID: 17577017
    • Carver JR, Shapiro CL, Ng A, et al. American Society of Clinical Oncology clinical evidence review on the ongoing care of adult cancer survivors: cardiac and pulmonary late effects. J Clin Oncol. 2007;25:3991–4008.
    • (2007) J Clin Oncol , vol.25 , pp. 3991-4008
    • Carver, J.R.1    Shapiro, C.L.2    Ng, A.3
  • 25
    • 33644876141 scopus 로고    scopus 로고
    • NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity
    • COI: 1:CAS:528:DC%2BD2MXht1yitb7K, PID: 16330681
    • Wojnowski L, Kulle B, Schirmer M, et al. NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity. Circulation. 2005;112:3754–62.
    • (2005) Circulation , vol.112 , pp. 3754-3762
    • Wojnowski, L.1    Kulle, B.2    Schirmer, M.3
  • 26
    • 51649092308 scopus 로고    scopus 로고
    • Cardiac management during adjuvant trastuzumab therapy: recommendations of the Canadian Trastuzumab Working Group
    • COI: 1:STN:280:DC%2BD1c7lvVKmtQ%3D%3D, PID: 18317582
    • Mackey JR, Clemons M, Cote MA, et al. Cardiac management during adjuvant trastuzumab therapy: recommendations of the Canadian Trastuzumab Working Group. Curr Oncol. 2008;15:24–35.
    • (2008) Curr Oncol , vol.15 , pp. 24-35
    • Mackey, J.R.1    Clemons, M.2    Cote, M.A.3
  • 27
    • 0017893505 scopus 로고
    • Variability in sequential measures of left ventricular performance assessed with radionuclide angiocardiography
    • COI: 1:STN:280:DyaE1c7itFSntQ%3D%3D, PID: 626129
    • Marshall RC, Berger HJ, Reduto LA, et al. Variability in sequential measures of left ventricular performance assessed with radionuclide angiocardiography. Am J Cardiol. 1978;41:531–6.
    • (1978) Am J Cardiol , vol.41 , pp. 531-536
    • Marshall, R.C.1    Berger, H.J.2    Reduto, L.A.3
  • 28
    • 84872033896 scopus 로고    scopus 로고
    • Reproducibility of echocardiographic techniques for sequential assessment of left ventricular ejection fraction and volumes: application to patients undergoing cancer chemotherapy
    • PID: 23199515
    • Thavendiranathan P, Grant AD, Negishi T, et al. Reproducibility of echocardiographic techniques for sequential assessment of left ventricular ejection fraction and volumes: application to patients undergoing cancer chemotherapy. J Am Coll Cardiol. 2013;61:77–84.
    • (2013) J Am Coll Cardiol , vol.61 , pp. 77-84
    • Thavendiranathan, P.1    Grant, A.D.2    Negishi, T.3
  • 29
    • 77955294878 scopus 로고    scopus 로고
    • Role of three-dimensional echocardiography in breast cancer: comparison with two-dimensional echocardiography, multiple-gated acquisition scans, and cardiac magnetic resonance imaging
    • Walker J, Bhullar N, Fallah-Rad N, et al. Role of three-dimensional echocardiography in breast cancer: comparison with two-dimensional echocardiography, multiple-gated acquisition scans, and cardiac magnetic resonance imaging. J Clin Onc. 2010;28:3429–36.
    • (2010) J Clin Onc , vol.28 , pp. 3429-3436
    • Walker, J.1    Bhullar, N.2    Fallah-Rad, N.3
  • 30
    • 55149092326 scopus 로고    scopus 로고
    • American Society of Echocardiography consensus statement on the clinical applications of ultrasonic contrast agents in echocardiography
    • PID: 18992671
    • Mulvagh SL, Rakowski H, Vannan MA, et al. American Society of Echocardiography consensus statement on the clinical applications of ultrasonic contrast agents in echocardiography. J Am Soc Echocardiogr. 2008;21:1179–201.
    • (2008) J Am Soc Echocardiogr , vol.21 , pp. 1179-1201
    • Mulvagh, S.L.1    Rakowski, H.2    Vannan, M.A.3
  • 31
    • 0024373675 scopus 로고
    • Early detection of doxorubicin cardiotoxicity: interest of Doppler echocardiographic analysis of left ventricular filling dynamics
    • COI: 1:STN:280:DyaL1MzgtVGmsA%3D%3D, PID: 2741800
    • Marchandise B, Schroeder E, Bosly A, et al. Early detection of doxorubicin cardiotoxicity: interest of Doppler echocardiographic analysis of left ventricular filling dynamics. Am Heart J. 1989;118:92–8.
    • (1989) Am Heart J , vol.118 , pp. 92-98
    • Marchandise, B.1    Schroeder, E.2    Bosly, A.3
  • 32
    • 0026694165 scopus 로고
    • Prolongation of isovolumetric relaxation time as assessed by Doppler echocardiography predicts doxorubicin-induced systolic dysfunction in humans
    • COI: 1:STN:280:DyaK383pvFymsQ%3D%3D, PID: 1607540
    • Stoddard MF, Seeger J, Liddell NE, et al. Prolongation of isovolumetric relaxation time as assessed by Doppler echocardiography predicts doxorubicin-induced systolic dysfunction in humans. J Am Coll Cardiol. 1992;20:62–9.
    • (1992) J Am Coll Cardiol , vol.20 , pp. 62-69
    • Stoddard, M.F.1    Seeger, J.2    Liddell, N.E.3
  • 33
    • 32944478766 scopus 로고    scopus 로고
    • Tissue Doppler imaging and conventional echocardiography after anthracycline treatment in adults: early and late alterations of left ventricular function during a prospective study
    • PID: 15941672
    • Tassan-Mangina S, Codorean D, Metivier M, et al. Tissue Doppler imaging and conventional echocardiography after anthracycline treatment in adults: early and late alterations of left ventricular function during a prospective study. Eur J Echocardiogr. 2006;7:141–6.
    • (2006) Eur J Echocardiogr , vol.7 , pp. 141-146
    • Tassan-Mangina, S.1    Codorean, D.2    Metivier, M.3
  • 34
    • 84872043378 scopus 로고    scopus 로고
    • Is echocardiography reliable for monitoring the adverse cardiac effects of chemotherapy?
    • PID: 23199517, An important article describing the role and limitations of echocardiography in monitoring cardiac function in patients receiving cardiotoxic cancer therapy
    • • Mor-Avi V, Lang RM. Is echocardiography reliable for monitoring the adverse cardiac effects of chemotherapy? J Am Coll Cardiol. 2013;61:85–7. An important article describing the role and limitations of echocardiography in monitoring cardiac function in patients receiving cardiotoxic cancer therapy
    • (2013) J Am Coll Cardiol , vol.61 , pp. 85-87
    • Mor-Avi, V.1    Lang, R.M.2
  • 35
    • 84903142814 scopus 로고    scopus 로고
    • Use of myocardial strain imaging by echocardiography for the early detection of cardiotoxicity in patients during and after cancer chemotherapy: a systematic review
    • PID: 24703918, Important article describing the role of echocardiographic strain imaging for monitoring cardiotoxicity of cancer therapy
    • •• Thavendiranathan P, Poulin F, Lim KD, et al. Use of myocardial strain imaging by echocardiography for the early detection of cardiotoxicity in patients during and after cancer chemotherapy: a systematic review. J Am Coll Cardiol. 2014;63:2751–68. Important article describing the role of echocardiographic strain imaging for monitoring cardiotoxicity of cancer therapy
    • (2014) J Am Coll Cardiol , vol.63 , pp. 2751-2768
    • Thavendiranathan, P.1    Poulin, F.2    Lim, K.D.3
  • 36
    • 79954593490 scopus 로고    scopus 로고
    • Early detection and prediction of cardiotoxicity in chemotherapy-treated patients
    • COI: 1:CAS:528:DC%2BC3MXkvVWgtrY%3D, PID: 21371685
    • Sawaya H, Sebag IA, Plana JC, et al. Early detection and prediction of cardiotoxicity in chemotherapy-treated patients. Am J Cardiol. 2011;107:1375–80.
    • (2011) Am J Cardiol , vol.107 , pp. 1375-1380
    • Sawaya, H.1    Sebag, I.A.2    Plana, J.C.3
  • 37
    • 84866164871 scopus 로고    scopus 로고
    • Assessment of echocardiography and biomarkers for the extended prediction of cardiotoxicity in patients treated with anthracyclines, taxanes, and trastuzumab
    • PID: 22744937
    • Sawaya H, Sebag IA, Plana JC, et al. Assessment of echocardiography and biomarkers for the extended prediction of cardiotoxicity in patients treated with anthracyclines, taxanes, and trastuzumab. Circulation Cardiovascular Imaging. 2012;5:596–603.
    • (2012) Circulation Cardiovascular Imaging , vol.5 , pp. 596-603
    • Sawaya, H.1    Sebag, I.A.2    Plana, J.C.3
  • 38
    • 77955907895 scopus 로고    scopus 로고
    • Role of biomarkers in chemotherapy-induced cardiotoxicity
    • COI: 1:CAS:528:DC%2BC3cXhtVGmt7rM, PID: 20728699
    • Cardinale D, Sandri MT. Role of biomarkers in chemotherapy-induced cardiotoxicity. Prog Cardiovasc Dis. 2010;53:121–9.
    • (2010) Prog Cardiovasc Dis , vol.53 , pp. 121-129
    • Cardinale, D.1    Sandri, M.T.2
  • 39
    • 55249107586 scopus 로고    scopus 로고
    • Biochemical markers for prediction of chemotherapy-induced cardiotoxicity: systematic review of the literature and recommendations for use
    • COI: 1:CAS:528:DC%2BD1cXhsVSjtrbL, PID: 18854260
    • Dolci A, Dominici R, Cardinale D, et al. Biochemical markers for prediction of chemotherapy-induced cardiotoxicity: systematic review of the literature and recommendations for use. Am J Clin Pathol. 2008;130:688–95.
    • (2008) Am J Clin Pathol , vol.130 , pp. 688-695
    • Dolci, A.1    Dominici, R.2    Cardinale, D.3
  • 40
    • 79957576807 scopus 로고    scopus 로고
    • The utility of cardiac biomarkers, tissue velocity and strain imaging, and cardiac magnetic resonance imaging in predicting early left ventricular dysfunction in patients with human epidermal growth factor receptor II-positive breast cancer treated with adjuvant trastuzumab therapy
    • COI: 1:CAS:528:DC%2BC3MXot1yjsbg%3D, PID: 21616287
    • Fallah-Rad N, Walker JR, Wassef A, et al. The utility of cardiac biomarkers, tissue velocity and strain imaging, and cardiac magnetic resonance imaging in predicting early left ventricular dysfunction in patients with human epidermal growth factor receptor II-positive breast cancer treated with adjuvant trastuzumab therapy. J Am Coll Cardiol. 2011;57:2263–70.
    • (2011) J Am Coll Cardiol , vol.57 , pp. 2263-2270
    • Fallah-Rad, N.1    Walker, J.R.2    Wassef, A.3
  • 41
    • 56549101641 scopus 로고    scopus 로고
    • Strain rate imaging detects early cardiac effects of pegylated liposomal doxorubicin as adjuvant therapy in elderly patients with breast cancer
    • PID: 19041569
    • Jurcut R, Wildiers H, Ganame J, et al. Strain rate imaging detects early cardiac effects of pegylated liposomal doxorubicin as adjuvant therapy in elderly patients with breast cancer. J Am Soc Echocardiogr. 2008;21:1283–9.
    • (2008) J Am Soc Echocardiogr , vol.21 , pp. 1283-1289
    • Jurcut, R.1    Wildiers, H.2    Ganame, J.3
  • 42
    • 84870555288 scopus 로고    scopus 로고
    • Continuous versus bolus infusion of doxorubicin in children with ALL: long-term cardiac outcomes
    • PID: 23166343
    • Lipshultz SE, Miller TL, Lipsitz SR, et al. Continuous versus bolus infusion of doxorubicin in children with ALL: long-term cardiac outcomes. Pediatrics. 2012;130:1003–11. doi:10.1542/peds.2012-0727.
    • (2012) Pediatrics , vol.130 , pp. 1003-1011
    • Lipshultz, S.E.1    Miller, T.L.2    Lipsitz, S.R.3
  • 43
    • 84896392548 scopus 로고    scopus 로고
    • Multicenter experience of nonpegylated liposomal doxorubicin use in the management of metastatic breast cancer
    • COI: 1:CAS:528:DC%2BC3sXitVShurrN, PID: 24325950, Apr
    • Palmieri C, Misra V, Januszewski A, et al. Multicenter experience of nonpegylated liposomal doxorubicin use in the management of metastatic breast cancer. Clin Breast Cancer. 2014 Apr;14(2):85–93. doi:10.1016/j.clbc.2013.10.011.
    • (2014) Clin Breast Cancer , vol.14 , Issue.2 , pp. 85-93
    • Palmieri, C.1    Misra, V.2    Januszewski, A.3
  • 44
    • 85016969635 scopus 로고    scopus 로고
    • Children’s Oncology Group long-term follow up guidelines for survivors of childhood, adolescent and young adult cancer (version 4, Oct 2013). pp. 25–26
    • Children’s Oncology Group long-term follow up guidelines for survivors of childhood, adolescent and young adult cancer (version 4, Oct 2013). www.survivorshipguidelines.org/pdf/COG_LTFU_Guidelines_Appendix1_v4.pdf. pp. 25–26.
  • 45
    • 73549087024 scopus 로고    scopus 로고
    • Anthracycline-induced cardiomyopathy: clinical relevance and response to pharmacologic therapy
    • COI: 1:CAS:528:DC%2BC3cXitlagtrs%3D, PID: 20117401
    • Cardinale D, Colombo A, Lamantia G, et al. Anthracycline-induced cardiomyopathy: clinical relevance and response to pharmacologic therapy. J Am Coll Cardiol. 2010;55:213–20.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 213-220
    • Cardinale, D.1    Colombo, A.2    Lamantia, G.3
  • 46
    • 84900800135 scopus 로고    scopus 로고
    • A reevaluation of the costs of heart failure and its implications for allocation of health resources in the United States
    • PID: 24945038
    • Voigt J, Sasha John M, Taylor A, et al. A reevaluation of the costs of heart failure and its implications for allocation of health resources in the United States. Clin Cardiol. 2014;37:312–21.
    • (2014) Clin Cardiol , vol.37 , pp. 312-321
    • Voigt, J.1    Sasha John, M.2    Taylor, A.3
  • 47
    • 33947542048 scopus 로고    scopus 로고
    • Dexrazoxane-associated risk for acute myeloid leukemia/myelodysplastic syndrome and other secondary malignancies in pediatric Hodgkin’s disease
    • COI: 1:CAS:528:DC%2BD2sXivF2mt7c%3D, PID: 17290056
    • Tebbi CK, London WB, Friedman D, et al. Dexrazoxane-associated risk for acute myeloid leukemia/myelodysplastic syndrome and other secondary malignancies in pediatric Hodgkin’s disease. J Clin Oncol. 2007;25:493–500.
    • (2007) J Clin Oncol , vol.25 , pp. 493-500
    • Tebbi, C.K.1    London, W.B.2    Friedman, D.3
  • 48
    • 0036784463 scopus 로고    scopus 로고
    • Trastuzumab-associated cardiotoxicity
    • COI: 1:CAS:528:DC%2BD38XnvV2qur8%3D, PID: 12237930
    • Keefe DL. Trastuzumab-associated cardiotoxicity. Cancer. 2002;95:1592–600.
    • (2002) Cancer , vol.95 , pp. 1592-1600
    • Keefe, D.L.1
  • 49
    • 37349063756 scopus 로고    scopus 로고
    • Cardiotoxicity associated with the use of trastuzumab in breast cancer patients
    • COI: 1:CAS:528:DC%2BD2sXhsVSis7%2FO, PID: 18062750
    • Perik PJ, de Korte MA, van Veldhuisen DJ, et al. Cardiotoxicity associated with the use of trastuzumab in breast cancer patients. Expert Rev Anticancer Ther. 2007;7:1763–71.
    • (2007) Expert Rev Anticancer Ther , vol.7 , pp. 1763-1771
    • Perik, P.J.1    de Korte, M.A.2    van Veldhuisen, D.J.3
  • 50
    • 32144448027 scopus 로고    scopus 로고
    • Reversibility of trastuzumab-related cardiotoxicity: new insights based on clinical course and response to medical treatment
    • COI: 1:CAS:528:DC%2BD2MXht1Cqs7bP, PID: 16258084
    • Ewer MS, Vooletich MT, Durand JB, Woods ML, Davis JR, Valero V, et al. Reversibility of trastuzumab-related cardiotoxicity: new insights based on clinical course and response to medical treatment. J Clin Oncol. 2005;23:7820–6.
    • (2005) J Clin Oncol , vol.23 , pp. 7820-7826
    • Ewer, M.S.1    Vooletich, M.T.2    Durand, J.B.3    Woods, M.L.4    Davis, J.R.5    Valero, V.6
  • 51
    • 43849094005 scopus 로고    scopus 로고
    • Cardiotoxicity profile of trastuzumab
    • COI: 1:CAS:528:DC%2BD1cXosFGksLo%3D, PID: 18484781
    • Ewer SM, Ewer MS. Cardiotoxicity profile of trastuzumab. Drug Saf. 2008;31:459–67.
    • (2008) Drug Saf , vol.31 , pp. 459-467
    • Ewer, S.M.1    Ewer, M.S.2
  • 52
    • 84863265688 scopus 로고    scopus 로고
    • Endothelial-derived neuregulin is an important mediator of ischaemia-induced angiogenesis and arteriogenesis
    • COI: 1:CAS:528:DC%2BC38XivVOmtL8%3D, PID: 22200588
    • Hedhli N, Dobrucki LW, Kalinowski A, et al. Endothelial-derived neuregulin is an important mediator of ischaemia-induced angiogenesis and arteriogenesis. Cardiovasc Res. 2012;93:516–24.
    • (2012) Cardiovasc Res , vol.93 , pp. 516-524
    • Hedhli, N.1    Dobrucki, L.W.2    Kalinowski, A.3
  • 53
    • 79958172866 scopus 로고    scopus 로고
    • Endothelium-derived neuregulin protects the heart against ischemic injury
    • Hedhli N, Huang Q, Kalinowski A, et al. Endothelium-derived neuregulin protects the heart against ischemic injury. Circulation. 2011.
    • (2011) Circulation
    • Hedhli, N.1    Huang, Q.2    Kalinowski, A.3
  • 54
    • 33845982943 scopus 로고    scopus 로고
    • Trastuzumab-induced cardiac dysfunction
    • PID: 17198344
    • Panjrath GS, Jain D. Trastuzumab-induced cardiac dysfunction. Nucl Med Commun. 2007;28:69–73.
    • (2007) Nucl Med Commun , vol.28 , pp. 69-73
    • Panjrath, G.S.1    Jain, D.2
  • 55
    • 84866599720 scopus 로고    scopus 로고
    • Cardiovascular toxicity induced by chemotherapy, targeted agents and radiotherapy: ESMO clinical practice guidelines
    • PID: 22997448
    • Curigliano G, Cardinale D, Suter T, et al. Cardiovascular toxicity induced by chemotherapy, targeted agents and radiotherapy: ESMO clinical practice guidelines. Ann Oncol. 2012;23(Suppl 7):vii155–66.
    • (2012) Ann Oncol , vol.23 , pp. vii155-vii166
    • Curigliano, G.1    Cardinale, D.2    Suter, T.3
  • 56
    • 84855297353 scopus 로고    scopus 로고
    • Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial
    • COI: 1:CAS:528:DC%2BC38XkslSmsQ%3D%3D, PID: 22153890
    • Gianni L, Pienkowski T, Im YH, et al. Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial. Lancet Oncol. 2012;13:25–32.
    • (2012) Lancet Oncol , vol.13 , pp. 25-32
    • Gianni, L.1    Pienkowski, T.2    Im, Y.H.3
  • 57
    • 77949884661 scopus 로고    scopus 로고
    • Randomized study of lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer
    • COI: 1:CAS:528:DC%2BC3cXktF2ltLo%3D, PID: 20124187
    • Blackwell KL, Burstein HJ, Storniolo AM, et al. Randomized study of lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer. J Clin Oncol. 2010;28:1124–30.
    • (2010) J Clin Oncol , vol.28 , pp. 1124-1130
    • Blackwell, K.L.1    Burstein, H.J.2    Storniolo, A.M.3
  • 58
    • 0035960101 scopus 로고    scopus 로고
    • Trastuzumab and breast cancer
    • COI: 1:CAS:528:DC%2BD3MXntlehtbk%3D, PID: 11575295
    • Behr TM, Behe M, Wormann B. Trastuzumab and breast cancer. N Engl J Med. 2001;345:995–6.
    • (2001) N Engl J Med , vol.345 , pp. 995-996
    • Behr, T.M.1    Behe, M.2    Wormann, B.3
  • 59
    • 84856736863 scopus 로고    scopus 로고
    • Distribution of coronary artery stenosis after radiation for breast cancer
    • Nilsson G, Holmberg L, Garmo H, et al. Distribution of coronary artery stenosis after radiation for breast cancer. J Clin Oncol. 2012;30:380–6.
    • (2012) J Clin Oncol , vol.30 , pp. 380-386
    • Nilsson, G.1    Holmberg, L.2    Garmo, H.3
  • 60
    • 0027069532 scopus 로고
    • Cardiotoxicity of high-dose continuous infusion fluorouracil: a prospective clinical study
    • de Forni M, Malet-Martino MC, Jaillais P, et al. Cardiotoxicity of high-dose continuous infusion fluorouracil: a prospective clinical study. J Clin Oncol. 1992;10:1795–801.
    • (1992) J Clin Oncol , vol.10 , pp. 1795-1801
    • de Forni, M.1    Malet-Martino, M.C.2    Jaillais, P.3
  • 61
    • 80052274711 scopus 로고    scopus 로고
    • Incidence of heart disease in 35,000 women treated with radiotherapy for breast cancer in Denmark and Sweden
    • McGale P, Darby SC, Hall P, et al. Incidence of heart disease in 35,000 women treated with radiotherapy for breast cancer in Denmark and Sweden. Radiotherapy and Oncology. 2011;100:167–75.
    • (2011) Radiotherapy and Oncology , vol.100 , pp. 167-175
    • McGale, P.1    Darby, S.C.2    Hall, P.3
  • 62
    • 84874984990 scopus 로고    scopus 로고
    • Risk of ischemic heart disease in women after radiotherapy for breast cancer
    • Darby SC, Ewertz M, McGale P, et al. Risk of ischemic heart disease in women after radiotherapy for breast cancer. N Engl J Med. 2013;368:987–98.
    • (2013) N Engl J Med , vol.368 , pp. 987-998
    • Darby, S.C.1    Ewertz, M.2    McGale, P.3
  • 63
    • 18144367799 scopus 로고    scopus 로고
    • The incidence and functional consequences of RT-associated cardiac perfusion defects
    • Marks LB, Yu X, Prosnitz RG, et al. The incidence and functional consequences of RT-associated cardiac perfusion defects. Int J Radiat Oncol Biol Phys. 2005;63:214–23.
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 214-223
    • Marks, L.B.1    Yu, X.2    Prosnitz, R.G.3
  • 64
    • 0036661468 scopus 로고    scopus 로고
    • Detection of defects in myocardial perfusion imaging in patients with early breast cancer treated with radiotherapy
    • Seddon B, Cook A, Gothard L, et al. Detection of defects in myocardial perfusion imaging in patients with early breast cancer treated with radiotherapy. Radiotherapy and Oncology. 2002;64:53–63.
    • (2002) Radiotherapy and Oncology , vol.64 , pp. 53-63
    • Seddon, B.1    Cook, A.2    Gothard, L.3
  • 65
    • 34547688921 scopus 로고    scopus 로고
    • Coronary artery findings after left-sided compared with right-sided radiation treatment for early-stage breast cancer
    • Correa CR, Litt HI, Hwang WT, et al. Coronary artery findings after left-sided compared with right-sided radiation treatment for early-stage breast cancer. J Clin Oncol. 2007;25:3031–7.
    • (2007) J Clin Oncol , vol.25 , pp. 3031-3037
    • Correa, C.R.1    Litt, H.I.2    Hwang, W.T.3
  • 66
    • 84871186267 scopus 로고    scopus 로고
    • Local heart irradiation of ApoE(-/-) mice induces microvascular and endocardial damage and accelerates coronary atherosclerosis
    • Gabriels K, Hoving S, Seemann I, et al. Local heart irradiation of ApoE(-/-) mice induces microvascular and endocardial damage and accelerates coronary atherosclerosis. Radiotherapy and Oncology. 2012;105:358–64.
    • (2012) Radiotherapy and Oncology , vol.105 , pp. 358-364
    • Gabriels, K.1    Hoving, S.2    Seemann, I.3
  • 67
    • 66949158016 scopus 로고    scopus 로고
    • Fluoropyrimidine-associated cardiotoxicity: revisited
    • COI: 1:CAS:528:DC%2BD1MXjsVOhsrw%3D, PID: 19309247
    • Saif MW, Shah MM, Shah AR. Fluoropyrimidine-associated cardiotoxicity: revisited. Expert Opin Drug Saf. 2009;8:191–202.
    • (2009) Expert Opin Drug Saf , vol.8 , pp. 191-202
    • Saif, M.W.1    Shah, M.M.2    Shah, A.R.3
  • 68
    • 0028280275 scopus 로고
    • Fluorouracil cardiotoxicity
    • COI: 1:STN:280:DyaK2c3ltV2qtQ%3D%3D, PID: 8193429
    • Anand AJ. Fluorouracil cardiotoxicity. Ann Pharmacother. 1994;28:374–8.
    • (1994) Ann Pharmacother , vol.28 , pp. 374-378
    • Anand, A.J.1
  • 69
    • 0025649990 scopus 로고
    • Acute coronary events following cisplatin-based chemotherapy
    • COI: 1:STN:280:DyaK3M7lt1GntQ%3D%3D
    • Berliner S, Rahima M, Sidi Y, et al. Acute coronary events following cisplatin-based chemotherapy. Cancer Investig. 1990;8:583–6.
    • (1990) Cancer Investig , vol.8 , pp. 583-586
    • Berliner, S.1    Rahima, M.2    Sidi, Y.3
  • 70
    • 0035985332 scopus 로고    scopus 로고
    • Capecitabine can induce acute coronary syndrome similar to 5-fluorouracil
    • COI: 1:STN:280:DC%2BD38zjtlWqtw%3D%3D, PID: 12075751
    • Frickhofen N, Beck FJ, Jung B, et al. Capecitabine can induce acute coronary syndrome similar to 5-fluorouracil. Ann Oncol. 2002;13:797–801.
    • (2002) Ann Oncol , vol.13 , pp. 797-801
    • Frickhofen, N.1    Beck, F.J.2    Jung, B.3
  • 71
    • 79551610758 scopus 로고    scopus 로고
    • Cardiotoxicity of kinase inhibitors: the prediction and translation of preclinical models to clinical outcomes
    • COI: 1:CAS:528:DC%2BC3MXhtlektrg%3D, PID: 21283106
    • Force T, Kolaja KL. Cardiotoxicity of kinase inhibitors: the prediction and translation of preclinical models to clinical outcomes. Nat Rev Drug Discov. 2011;10:111–26.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 111-126
    • Force, T.1    Kolaja, K.L.2
  • 72
    • 55949123335 scopus 로고    scopus 로고
    • Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma
    • PID: 18838713
    • Schmidinger M, Zielinski CC, Vogl UM, et al. Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma. J Clin Oncol. 2008;26:5204–12.
    • (2008) J Clin Oncol , vol.26 , pp. 5204-5212
    • Schmidinger, M.1    Zielinski, C.C.2    Vogl, U.M.3
  • 73
    • 36849023013 scopus 로고    scopus 로고
    • Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib
    • COI: 1:CAS:528:DC%2BD2sXhsVent7bN, PID: 18083403
    • Chu TF, Rupnick MA, Kerkela R, et al. Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib. Lancet. 2007;370:2011–9.
    • (2007) Lancet , vol.370 , pp. 2011-2019
    • Chu, T.F.1    Rupnick, M.A.2    Kerkela, R.3
  • 74
    • 84880566944 scopus 로고    scopus 로고
    • Coronary microvascular pericytes are the cellular target of sunitinib malate-induced cardiotoxicity
    • PID: 23720580
    • Chintalgattu V, Rees ML, Culver JC, et al. Coronary microvascular pericytes are the cellular target of sunitinib malate-induced cardiotoxicity. Sci Transl Med. 2013;5:187ra69.
    • (2013) Sci Transl Med , vol.5
    • Chintalgattu, V.1    Rees, M.L.2    Culver, J.C.3
  • 75
    • 0141533074 scopus 로고    scopus 로고
    • Assessment of fatty acid metabolism in taxan-induced myocardial damage with iodine-123 BMIPP SPECT: comparative study with myocardial perfusion, left ventricular function, and histopathological findings
    • COI: 1:CAS:528:DC%2BD3sXpslyrtrs%3D, PID: 14575384
    • Saito K, Takeda K, Imanaka-Yoshida K, et al. Assessment of fatty acid metabolism in taxan-induced myocardial damage with iodine-123 BMIPP SPECT: comparative study with myocardial perfusion, left ventricular function, and histopathological findings. Ann Nucl Med. 2003;17:481–8.
    • (2003) Ann Nucl Med , vol.17 , pp. 481-488
    • Saito, K.1    Takeda, K.2    Imanaka-Yoshida, K.3
  • 76
    • 0025799973 scopus 로고
    • Cardiac disturbances during the administration of taxol
    • COI: 1:STN:280:DyaK3MzktFGguw%3D%3D, PID: 1678781
    • Rowinsky EK, McGuire WP, Guarnieri T, et al. Cardiac disturbances during the administration of taxol. J Clin Oncol. 1991;9:1704–12.
    • (1991) J Clin Oncol , vol.9 , pp. 1704-1712
    • Rowinsky, E.K.1    McGuire, W.P.2    Guarnieri, T.3
  • 77
    • 0035192488 scopus 로고    scopus 로고
    • Kidney cancer: the Cytokine Working Group experience (1986-2001): part II. Management of IL-2 toxicity and studies with other cytokines
    • COI: 1:CAS:528:DC%2BD38Xmt1Wqur4%3D, PID: 11917945
    • Dutcher J, Atkins MB, Margolin K, et al. Kidney cancer: the Cytokine Working Group experience (1986-2001): part II. Management of IL-2 toxicity and studies with other cytokines. Med Oncol. 2001;18:209–19.
    • (2001) Med Oncol , vol.18 , pp. 209-219
    • Dutcher, J.1    Atkins, M.B.2    Margolin, K.3
  • 78
    • 0033024863 scopus 로고    scopus 로고
    • High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993
    • COI: 1:CAS:528:DyaK1MXkvVSmur4%3D, PID: 10561265
    • Atkins MB, Lotze MT, Dutcher JP, et al. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J Clin Oncol. 1999;17:2105–16.
    • (1999) J Clin Oncol , vol.17 , pp. 2105-2116
    • Atkins, M.B.1    Lotze, M.T.2    Dutcher, J.P.3
  • 79
    • 84940403833 scopus 로고    scopus 로고
    • PD-1 blockers
    • Wolchok JD. PD-1 blockers. Cell. 2015;162:93.
    • (2015) Cell , vol.162 , pp. 93
    • Wolchok, J.D.1
  • 80
    • 84930630766 scopus 로고    scopus 로고
    • PD-1/PD-L1 inhibitors
    • COI: 1:CAS:528:DC%2BC2MXptFShu7k%3D
    • Sunshine J, Taube JM. PD-1/PD-L1 inhibitors. Curr Opinions Pharm. 2015;23:32–8.
    • (2015) Curr Opinions Pharm , vol.23 , pp. 32-38
    • Sunshine, J.1    Taube, J.M.2
  • 81
    • 84994057015 scopus 로고    scopus 로고
    • Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
    • COI: 1:CAS:528:DC%2BC28XhvVSisb7M, PID: 27796306
    • Lee JY, Lee HT, Shin W, et al. Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy. Nat Commun. 2016;7:13354. doi:10.1038/ncomms13354.
    • (2016) Nat Commun , vol.7 , pp. 13354
    • Lee, J.Y.1    Lee, H.T.2    Shin, W.3
  • 82
    • 84899873585 scopus 로고    scopus 로고
    • Endocrine-related adverse events following ipilimumab in patients with advanced melanoma: a comprehensive retrospective review from a single institution
    • COI: 1:CAS:528:DC%2BC2cXpsVSlsbg%3D, PID: 24610577
    • Ryder M, Callahan M, Postow MA, et al. Endocrine-related adverse events following ipilimumab in patients with advanced melanoma: a comprehensive retrospective review from a single institution. Endocr Relat Cancer. 2014;21:371–81.
    • (2014) Endocr Relat Cancer , vol.21 , pp. 371-381
    • Ryder, M.1    Callahan, M.2    Postow, M.A.3
  • 83
    • 84978962950 scopus 로고    scopus 로고
    • A novel melanoma therapy stirs up a storm: ipilimumab-induced thyrotoxicosis
    • PID: 25759760
    • Yu C, Chopra IJ, Ha E. A novel melanoma therapy stirs up a storm: ipilimumab-induced thyrotoxicosis. Endocrinol Diabetes Metab Case Rep. 2015;2015:140092.
    • (2015) Endocrinol Diabetes Metab Case Rep , vol.2015 , pp. 140092
    • Yu, C.1    Chopra, I.J.2    Ha, E.3
  • 84
    • 84994144982 scopus 로고    scopus 로고
    • Fulminant myocarditis with combined checkpoint inhibitors
    • PID: 27806233, A recent article describing catastrophic cardiac complications in patients undergoing therapy with a highly promising new group of anticancer medications. The use of this group of medicaitons is likely to grow exponentially in the coming years
    • • Johnson DB, Balko JM, Compton ML, et al. Fulminant myocarditis with combined checkpoint inhibitors. N Engl J Med. 2016;375:1749–55. A recent article describing catastrophic cardiac complications in patients undergoing therapy with a highly promising new group of anticancer medications. The use of this group of medicaitons is likely to grow exponentially in the coming years
    • (2016) N Engl J Med , vol.375 , pp. 1749-1755
    • Johnson, D.B.1    Balko, J.M.2    Compton, M.L.3
  • 85
    • 84991219713 scopus 로고    scopus 로고
    • Cardiovascular toxic effects of targeted cancer therapies
    • COI: 1:CAS:528:DC%2BC28XhvF2ksrnI, PID: 27732808, An excellent recent review article describing cardiotoxicity of newer targeted cancer therapies
    • •• Moslehi JJ. Cardiovascular toxic effects of targeted cancer therapies. N Engl J Med. 2016;375:1457–67. An excellent recent review article describing cardiotoxicity of newer targeted cancer therapies
    • (2016) N Engl J Med , vol.375 , pp. 1457-1467
    • Moslehi, J.J.1
  • 86
    • 77956658504 scopus 로고    scopus 로고
    • Cardiac PET imaging for the detection and monitoring of coronary artery disease and microvascular health
    • PID: 20541718
    • Schindler TH, Schelbert HR, Quercioli A, Dilsizian V. Cardiac PET imaging for the detection and monitoring of coronary artery disease and microvascular health. JACC Cardiovasc Imaging. 2010;3:623–40.
    • (2010) JACC Cardiovasc Imaging , vol.3 , pp. 623-640
    • Schindler, T.H.1    Schelbert, H.R.2    Quercioli, A.3    Dilsizian, V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.