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Volumn 148, Issue 2, 2017, Pages 173-187

Low molecular weight hyaluronan induces migration of human choriocarcinoma JEG-3 cells mediated by RHAMM as well as by PI3K and MAPK pathways

Author keywords

Choriocarcinoma; Hyaluronan; Hydatidiform mole; Migration; RHAMM; Signalling pathways

Indexed keywords

HERMES ANTIGEN; HYALURONIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN RHAMM; RECEPTOR PROTEIN; UNCLASSIFIED DRUG; HYALURONAN-MEDIATED MOTILITY RECEPTOR; HYALURONIC ACID BINDING PROTEIN; SCLEROPROTEIN;

EID: 85016500506     PISSN: 09486143     EISSN: 1432119X     Source Type: Journal    
DOI: 10.1007/s00418-017-1559-3     Document Type: Article
Times cited : (24)

References (54)
  • 1
    • 33646145082 scopus 로고    scopus 로고
    • Hyaluronan oligosaccharides induce cell death through PI3-K/Akt pathway independently of NF- B transcription factor
    • COI: 1:CAS:528:DC%2BD28XjslKkur0%3D, PID: 16461453
    • Alaniz L, García MG, Gallo-Rodriguez C, Agusti R, Sterín-Speziale N, Hajos SE, Alvarez E (2006) Hyaluronan oligosaccharides induce cell death through PI3-K/Akt pathway independently of NF- B transcription factor. Glycobiology 16:359–367
    • (2006) Glycobiology , vol.16 , pp. 359-367
    • Alaniz, L.1    García, M.G.2    Gallo-Rodriguez, C.3    Agusti, R.4    Sterín-Speziale, N.5    Hajos, S.E.6    Alvarez, E.7
  • 2
    • 0031850550 scopus 로고    scopus 로고
    • The human hyaluronan receptor RHAMM is expressed as an intracellular protein in breast cancer cells
    • COI: 1:CAS:528:DyaK1cXksFant7s%3D, PID: 9601098
    • Assmann V, Marshall JF, Fieber C, Hofmann M, Hart IR (1998) The human hyaluronan receptor RHAMM is expressed as an intracellular protein in breast cancer cells. J Cell Sci 111:1685–1694
    • (1998) J Cell Sci , vol.111 , pp. 1685-1694
    • Assmann, V.1    Marshall, J.F.2    Fieber, C.3    Hofmann, M.4    Hart, I.R.5
  • 4
    • 37349028055 scopus 로고    scopus 로고
    • Putative role of hyaluronan and its related genes, HAS2andRHAMM, in human early preimplantation embryogenesis and embryonic stem cell characterization
    • COI: 1:CAS:528:DC%2BD1cXnvFClsA%3D%3D, PID: 17872502
    • Choudhary M, Zhang X, Stojković P, Hyslop L, Anyfantis G, Herbert M, Murdoch AP, Stojković M, Lako M (2007) Putative role of hyaluronan and its related genes, HAS2andRHAMM, in human early preimplantation embryogenesis and embryonic stem cell characterization. Stem Cells 25:3045–3057
    • (2007) Stem Cells , vol.25 , pp. 3045-3057
    • Choudhary, M.1    Zhang, X.2    Stojković, P.3    Hyslop, L.4    Anyfantis, G.5    Herbert, M.6    Murdoch, A.P.7    Stojković, M.8    Lako, M.9
  • 5
    • 77955818331 scopus 로고    scopus 로고
    • Biological functions of hCG and hCG-related molecules
    • PID: 20735820
    • Cole LA (2010) Biological functions of hCG and hCG-related molecules. Reprod Biol Endocrinol 8:102
    • (2010) Reprod Biol Endocrinol , vol.8 , pp. 102
    • Cole, L.A.1
  • 6
    • 77957020564 scopus 로고    scopus 로고
    • Hyaluronan induces migration of multidrug-resistant lymphoma cell lines in vitro through Tiam1 activation by a PI3K-dependent mechanism
    • COI: 1:CAS:528:DC%2BC3cXht1WmurzL, PID: 20299090
    • Cordo Russo RI, Alaniz LD, Saccodossi N, Lompardía S, Blanco G, Álvarez É, García MG, Hajos SE (2010) Hyaluronan induces migration of multidrug-resistant lymphoma cell lines in vitro through Tiam1 activation by a PI3K-dependent mechanism. Leuk Res 34:1525–1532
    • (2010) Leuk Res , vol.34 , pp. 1525-1532
    • Cordo Russo, R.I.1    Alaniz, L.D.2    Saccodossi, N.3    Lompardía, S.4    Blanco, G.5    Álvarez, É.6    García, M.G.7    Hajos, S.E.8
  • 7
    • 84864303917 scopus 로고    scopus 로고
    • Increased hyaluronan levels and decreased dendritic cell activation are associated with tumor invasion in murine lymphoma cell lines
    • COI: 1:CAS:528:DC%2BC38XhvFejsL4%3D, PID: 22304941
    • Cordo Russo RI, Ernst G, Lompardía S, Blanco G, Álvarez É, Garcia MG, Hajos S (2012) Increased hyaluronan levels and decreased dendritic cell activation are associated with tumor invasion in murine lymphoma cell lines. Immunobiology 217:842–850
    • (2012) Immunobiology , vol.217 , pp. 842-850
    • Cordo Russo, R.I.1    Ernst, G.2    Lompardía, S.3    Blanco, G.4    Álvarez, É.5    Garcia, M.G.6    Hajos, S.7
  • 8
    • 84995938229 scopus 로고    scopus 로고
    • Endotoxin free hyaluronan and hyaluronan fragments do not stimulate TNF-α, interleukin-12 or upregulate costimulatory molecules in dendritic cells or macrophages
    • Dong Y, Arif A, Olsson M, Cali V, Hardman B, Dosanjh M, Lauer M, Midura RJ, Hascall VC, Brown KL, Johnson P (2016) Endotoxin free hyaluronan and hyaluronan fragments do not stimulate TNF-α, interleukin-12 or upregulate costimulatory molecules in dendritic cells or macrophages. Sci Rep 6:36928
    • (2016) Sci Rep , vol.6 , pp. 36928
    • Dong, Y.1    Arif, A.2    Olsson, M.3    Cali, V.4    Hardman, B.5    Dosanjh, M.6    Lauer, M.7    Midura, R.J.8    Hascall, V.C.9    Brown, K.L.10    Johnson, P.11
  • 11
    • 67650504966 scopus 로고    scopus 로고
    • TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays
    • PID: 19450233
    • Gebäck T, Peter Schulz MM, Koumoutsakos P, Detmar M (2009) TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays. Biotechniques 46:265–274
    • (2009) Biotechniques , vol.46 , pp. 265-274
    • Gebäck, T.1    Peter Schulz, M.M.2    Koumoutsakos, P.3    Detmar, M.4
  • 12
  • 13
    • 33749647713 scopus 로고    scopus 로고
    • Hyaluronan induces vascular smooth muscle cell migration through RHAMM-mediated PI3K-dependent Rac activation
    • COI: 1:CAS:528:DC%2BD28XhtVygsLnI, PID: 16934786
    • Goueffic Y, Guilluy C, Guerin P, Patra P, Pacaud P, Loirand G (2006) Hyaluronan induces vascular smooth muscle cell migration through RHAMM-mediated PI3K-dependent Rac activation. Cardiovasc Res 72:339–348
    • (2006) Cardiovasc Res , vol.72 , pp. 339-348
    • Goueffic, Y.1    Guilluy, C.2    Guerin, P.3    Patra, P.4    Pacaud, P.5    Loirand, G.6
  • 16
    • 34447530390 scopus 로고    scopus 로고
    • The hyaluronan receptors CD44 and rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cells
    • COI: 1:CAS:528:DC%2BD2sXlvVajurg%3D, PID: 17392272
    • Hamilton SR, Fard SF, Paiwand FF, Tolg C, Veiseh M, Wang C, Mccarthy JB, Bissell MJ, Koropatnick J, Turley EA (2007) The hyaluronan receptors CD44 and rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cells. J Biol Chem 282:16667–16680
    • (2007) J Biol Chem , vol.282 , pp. 16667-16680
    • Hamilton, S.R.1    Fard, S.F.2    Paiwand, F.F.3    Tolg, C.4    Veiseh, M.5    Wang, C.6    Mccarthy, J.B.7    Bissell, M.J.8    Koropatnick, J.9    Turley, E.A.10
  • 17
    • 79952088448 scopus 로고    scopus 로고
    • RHAMM/ERK interaction induces proliferative activities of cementifying fibroma cells through a mechanism based on the CD44–EGFR
    • PID: 20956971
    • Hatano H, Shigeishi H, Kudo Y, Higashikawa K, Tobiume K, Takata T, Kamata N (2010) RHAMM/ERK interaction induces proliferative activities of cementifying fibroma cells through a mechanism based on the CD44–EGFR. Lab Invest 91:379–391
    • (2010) Lab Invest , vol.91 , pp. 379-391
    • Hatano, H.1    Shigeishi, H.2    Kudo, Y.3    Higashikawa, K.4    Tobiume, K.5    Takata, T.6    Kamata, N.7
  • 18
    • 84901272575 scopus 로고    scopus 로고
    • Recombinant human hyaluronidase PH20 does not stimulate an acute inflammatory response and inhibits lipopolysaccharide-induced neutrophil recruitment in the air pouch model of inflammation
    • Huang Z, Zhao C, Chen Y, Cowell JA, Wei G, Kultti A, Huang L, Thompson CB, Rosengren S, Frost GI, Shepard HM (2014) Recombinant human hyaluronidase PH20 does not stimulate an acute inflammatory response and inhibits lipopolysaccharide-induced neutrophil recruitment in the air pouch model of inflammation. J Immunol 192:5285–5295
    • (2014) J Immunol , vol.192 , pp. 5285-5295
    • Huang, Z.1    Zhao, C.2    Chen, Y.3    Cowell, J.A.4    Wei, G.5    Kultti, A.6    Huang, L.7    Thompson, C.B.8    Rosengren, S.9    Frost, G.I.10    Shepard, H.M.11
  • 19
    • 78751670809 scopus 로고    scopus 로고
    • Hyaluronan as an immune regulator in human diseases
    • COI: 1:CAS:528:DC%2BC3MXisVCht70%3D, PID: 21248167
    • Jiang D, Liang J, Noble P (2011) Hyaluronan as an immune regulator in human diseases. Physiol Rev 91:221–264
    • (2011) Physiol Rev , vol.91 , pp. 221-264
    • Jiang, D.1    Liang, J.2    Noble, P.3
  • 20
    • 84883324629 scopus 로고    scopus 로고
    • The cytoskeletal protein RHAMM and ERK1/2 activity mantain the pluripotency of murine embryonic stem cells
    • COI: 1:CAS:528:DC%2BC3sXhsVCku7bL, PID: 24019927
    • Jiang J, Mohan P, Maxwell CA (2013) The cytoskeletal protein RHAMM and ERK1/2 activity mantain the pluripotency of murine embryonic stem cells. PLoS One 8:e73548
    • (2013) PLoS One , vol.8
    • Jiang, J.1    Mohan, P.2    Maxwell, C.A.3
  • 21
    • 0036084793 scopus 로고    scopus 로고
    • Growth-associated gene expression profiles by microarray analysis of trophoblast of molar pregnancies and normal villi
    • COI: 1:STN:280:DC%2BD38zkvFSjsw%3D%3D, PID: 12068171
    • Kato HD, Terao Y, Ogawa M, Matsuda T, Arima T, Kato K, Yong Z, Wake N (2002) Growth-associated gene expression profiles by microarray analysis of trophoblast of molar pregnancies and normal villi. Int J Gynecol Pathol 21:255–260
    • (2002) Int J Gynecol Pathol , vol.21 , pp. 255-260
    • Kato, H.D.1    Terao, Y.2    Ogawa, M.3    Matsuda, T.4    Arima, T.5    Kato, K.6    Yong, Z.7    Wake, N.8
  • 22
    • 80055068206 scopus 로고    scopus 로고
    • Role of receptor for hyaluronic acid-mediated motility (RHAMM) in low molecular weight hyaluronan (LMWHA)-mediated fibrosarcoma cell adhesion
    • COI: 1:CAS:528:DC%2BC3MXhtlykur7F, PID: 21914806
    • Kouvidi K, Berdiaki A, Nikitovic D, Katonis P, Afratis N, Hascall VC, Karamanos NK, Tzanakakis GN (2011) Role of receptor for hyaluronic acid-mediated motility (RHAMM) in low molecular weight hyaluronan (LMWHA)-mediated fibrosarcoma cell adhesion. J Biol Chem 286:38509–38520
    • (2011) J Biol Chem , vol.286 , pp. 38509-38520
    • Kouvidi, K.1    Berdiaki, A.2    Nikitovic, D.3    Katonis, P.4    Afratis, N.5    Hascall, V.C.6    Karamanos, N.K.7    Tzanakakis, G.N.8
  • 23
    • 84887923318 scopus 로고    scopus 로고
    • Human leukemic cell lines synthesize hyaluronan to avoid senescence and resist chemotherapy
    • PID: 24013961
    • Lompardía SL, Papademetrio DL, Mascaró M, Álvarez EMDC, Hajos SE (2013) Human leukemic cell lines synthesize hyaluronan to avoid senescence and resist chemotherapy. Glycobiology 23:1463–1476
    • (2013) Glycobiology , vol.23 , pp. 1463-1476
    • Lompardía, S.L.1    Papademetrio, D.L.2    Mascaró, M.3    Álvarez, E.M.D.C.4    Hajos, S.E.5
  • 25
    • 77955051047 scopus 로고    scopus 로고
    • Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer
    • COI: 1:CAS:528:DC%2BC3cXpt1Oitrs%3D, PID: 20606680
    • Lugli A, Iezzi G, Hostettler I, Muraro MG, Mele V, Tornillo L, Carafa V, Spagnoli G, Terracciano L, Zlobec I (2010) Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer. Br J Cancer 103:382–390
    • (2010) Br J Cancer , vol.103 , pp. 382-390
    • Lugli, A.1    Iezzi, G.2    Hostettler, I.3    Muraro, M.G.4    Mele, V.5    Tornillo, L.6    Carafa, V.7    Spagnoli, G.8    Terracciano, L.9    Zlobec, I.10
  • 27
    • 34247892927 scopus 로고    scopus 로고
    • Immunohistochemistry of choriocarcinoma: an aid in differential diagnosis and in elucidating pathogenesis
    • PID: 18059230
    • Mao T-L, Kurman RJ, Huang C-C, Lin M-C, Shih I-M (2007) Immunohistochemistry of choriocarcinoma: an aid in differential diagnosis and in elucidating pathogenesis. Am J Surg Pathol 31:1726–1732
    • (2007) Am J Surg Pathol , vol.31 , pp. 1726-1732
    • Mao, T.-L.1    Kurman, R.J.2    Huang, C.-C.3    Lin, M.-C.4    Shih, I.-M.5
  • 28
    • 43149106462 scopus 로고    scopus 로고
    • Cell-surface and mitotic-spindle RHAMM: moonlighting or dual oncogenic functions?
    • COI: 1:CAS:528:DC%2BD1cXlsF2nsLk%3D, PID: 18354082
    • Maxwell CA, Mccarthy J, Turley E (2008) Cell-surface and mitotic-spindle RHAMM: moonlighting or dual oncogenic functions? J Cell Sci 121:925–932
    • (2008) J Cell Sci , vol.121 , pp. 925-932
    • Maxwell, C.A.1    Mccarthy, J.2    Turley, E.3
  • 29
    • 84934289193 scopus 로고    scopus 로고
    • Hyaluronan—a functional and structural sweet spot in the tissue microenvironment frontiers
    • Monslow J, Govindaraju P, Puré E (2015) Hyaluronan—a functional and structural sweet spot in the tissue microenvironment frontiers. Immunology 6:231
    • (2015) Immunology , vol.6 , pp. 231
    • Monslow, J.1    Govindaraju, P.2    Puré, E.3
  • 30
    • 84962552024 scopus 로고    scopus 로고
    • Editorial: interaction between hyaluronic acid and its receptors (CD44 RHAMM) regulates the activity of inflammation cancer
    • PID: 26904028
    • Naor D (2016) Editorial: interaction between hyaluronic acid and its receptors (CD44 RHAMM) regulates the activity of inflammation cancer. Front Immunol 7:39
    • (2016) Front Immunol , vol.7 , pp. 39
    • Naor, D.1
  • 34
    • 9644254252 scopus 로고    scopus 로고
    • Trophoblast differentiation during embryo implantation and formation of the maternal-fetal interface
    • COI: 1:CAS:528:DC%2BD2cXnslWitbk%3D, PID: 15372095
    • Red-Horse K (2004) Trophoblast differentiation during embryo implantation and formation of the maternal-fetal interface. J Clin Invest 114:744–754
    • (2004) J Clin Invest , vol.114 , pp. 744-754
    • Red-Horse, K.1
  • 35
    • 33846393272 scopus 로고    scopus 로고
    • Expression of CD44, E-cadherin, and antimetastatic protein nm23-H1 in complete hydatidiform moles
    • COI: 1:CAS:528:DC%2BD2sXpvVKitQ%3D%3D, PID: 17027071
    • Reynolds E, Dubeshter B, Katzman P, Larson K, Katzel S, Glantz C (2007) Expression of CD44, E-cadherin, and antimetastatic protein nm23-H1 in complete hydatidiform moles. Gynecol Oncol 104:451–454
    • (2007) Gynecol Oncol , vol.104 , pp. 451-454
    • Reynolds, E.1    Dubeshter, B.2    Katzman, P.3    Larson, K.4    Katzel, S.5    Glantz, C.6
  • 36
    • 0035965301 scopus 로고    scopus 로고
    • Differential involvement of the hyaluronan (HA) receptors CD44 and receptor for HA-mediated motility in endothelial cell function and angiogenesis
    • COI: 1:CAS:528:DC%2BD3MXnt1yrurk%3D, PID: 11448954
    • Savani RC, Cao G, Pooler PM, Zaman A, Zhou Z, Delisser HM (2001) Differential involvement of the hyaluronan (HA) receptors CD44 and receptor for HA-mediated motility in endothelial cell function and angiogenesis. J Biol Chem 276:36770–36778
    • (2001) J Biol Chem , vol.276 , pp. 36770-36778
    • Savani, R.C.1    Cao, G.2    Pooler, P.M.3    Zaman, A.4    Zhou, Z.5    Delisser, H.M.6
  • 37
    • 75149115093 scopus 로고    scopus 로고
    • Histopathological diagnosis of hydatiform mole: contemporary features and clinical implications fetal and pediatric
    • COI: 1:CAS:528:DC%2BC3cXitl2mtA%3D%3D
    • Sebire N (2010) Histopathological diagnosis of hydatiform mole: contemporary features and clinical implications fetal and pediatric. Pathology 29:1–16
    • (2010) Pathology , vol.29 , pp. 1-16
    • Sebire, N.1
  • 38
    • 75149186968 scopus 로고    scopus 로고
    • Current issues in the histopathology of gestational trophoblastic tumors fetal and pediatric
    • COI: 1:CAS:528:DC%2BC3cXitl2mtQ%3D%3D
    • Sebire NJ, Lindsay I (2010) Current issues in the histopathology of gestational trophoblastic tumors fetal and pediatric. Pathology 29:30–44
    • (2010) Pathology , vol.29 , pp. 30-44
    • Sebire, N.J.1    Lindsay, I.2
  • 39
    • 34347273764 scopus 로고    scopus 로고
    • Gestational trophoblastic neoplasia—pathogenesis and potential therapeutic targets The
    • COI: 1:CAS:528:DC%2BD2sXnsFKkurg%3D, PID: 17613426
    • Shih I-M (2007) Gestational trophoblastic neoplasia—pathogenesis and potential therapeutic targets The. Lancet Oncol 8:642–650
    • (2007) Lancet Oncol , vol.8 , pp. 642-650
    • Shih, I.-M.1
  • 40
    • 0036304571 scopus 로고    scopus 로고
    • HLA-G immunoreactivity is specific for intermediate trophoblast in gestational trophoblastic disease and can serve as a useful marker in differential diagnosis
    • Singer G, Kurman RJ, Mcmaster M, Shih I (2002) HLA-G immunoreactivity is specific for intermediate trophoblast in gestational trophoblastic disease and can serve as a useful marker in differential diagnosis. Am J Surg Pathol 7:914–920
    • (2002) Am J Surg Pathol , vol.7 , pp. 914-920
    • Singer, G.1    Kurman, R.J.2    Mcmaster, M.3    Shih, I.4
  • 42
    • 33645372800 scopus 로고    scopus 로고
    • Hyaluronidases: their genomics, structures, and mechanisms of action
    • COI: 1:CAS:528:DC%2BD28XhtlOqs78%3D, PID: 16522010
    • Stern R, Jedrzejas M (2006) Hyaluronidases: their genomics, structures, and mechanisms of action. Chem Rev 106:818–839
    • (2006) Chem Rev , vol.106 , pp. 818-839
    • Stern, R.1    Jedrzejas, M.2
  • 44
    • 73349134974 scopus 로고    scopus 로고
    • Hyaluronan-CD44 Interactions in Cancer: Paradoxes and Possibilities
    • COI: 1:CAS:528:DC%2BD1MXhsFGgur3L, PID: 20008845
    • Toole BP (2009) Hyaluronan-CD44 Interactions in Cancer: Paradoxes and Possibilities. Clin Cancer Res 15:7462–7468
    • (2009) Clin Cancer Res , vol.15 , pp. 7462-7468
    • Toole, B.P.1
  • 45
    • 84859258205 scopus 로고    scopus 로고
    • RHAMM and CD44 peptides-analytic tools and potential drugs
    • Turley EA, Naor D (2012) RHAMM and CD44 peptides-analytic tools and potential drugs. Front Biosci 1:1775–1794
    • (2012) Front Biosci , vol.1 , pp. 1775-1794
    • Turley, E.A.1    Naor, D.2
  • 46
    • 0037085254 scopus 로고    scopus 로고
    • Signaling properties of hyaluronan receptors
    • PID: 11717317
    • Turley E, Noble P, Bourguignon L (2001) Signaling properties of hyaluronan receptors. J Biol Chem 277:4589–4592
    • (2001) J Biol Chem , vol.277 , pp. 4589-4592
    • Turley, E.1    Noble, P.2    Bourguignon, L.3
  • 47
    • 84969508713 scopus 로고    scopus 로고
    • Carcinoma cell hyaluronan as a “portable” cancerized prometastatic microenvironment
    • COI: 1:CAS:528:DC%2BC28XntVektb0%3D, PID: 27197262
    • Turley EA, Wood DK, Mccarthy JB (2016) Carcinoma cell hyaluronan as a “portable” cancerized prometastatic microenvironment. Cancer Res 76:2507–2512
    • (2016) Cancer Res , vol.76 , pp. 2507-2512
    • Turley, E.A.1    Wood, D.K.2    Mccarthy, J.B.3
  • 48
    • 77954938543 scopus 로고    scopus 로고
    • Hyaluronan stabilizes focal adhesions, filopodia, and the proliferative phenotype in esophageal squamous carcinoma cells
    • COI: 1:CAS:528:DC%2BC3cXovFelsb8%3D, PID: 20463012
    • Twarock S, Tammi MI, Savani RC, Fischer JW (2010) Hyaluronan stabilizes focal adhesions, filopodia, and the proliferative phenotype in esophageal squamous carcinoma cells. J Biol Chem 285:23276–23284
    • (2010) J Biol Chem , vol.285 , pp. 23276-23284
    • Twarock, S.1    Tammi, M.I.2    Savani, R.C.3    Fischer, J.W.4
  • 50
    • 0031948476 scopus 로고    scopus 로고
    • The overexpression of RHAMM, a hyaluronan-binding protein that regulates ras signaling, correlates with overexpression of mitogen-activated protein kinase and is a significant parameter in breast cancer progression
    • COI: 1:STN:280:DyaK1c7pt1Wqtg%3D%3D, PID: 9533523
    • Wang C, Thor A, Moore DN, Zhao Y, Kerschmann R, Stern R, Watson P, Turley E (1998) The overexpression of RHAMM, a hyaluronan-binding protein that regulates ras signaling, correlates with overexpression of mitogen-activated protein kinase and is a significant parameter in breast cancer progression. Clin Cancer Res 4:567–576
    • (1998) Clin Cancer Res , vol.4 , pp. 567-576
    • Wang, C.1    Thor, A.2    Moore, D.N.3    Zhao, Y.4    Kerschmann, R.5    Stern, R.6    Watson, P.7    Turley, E.8
  • 51
    • 37549017360 scopus 로고    scopus 로고
    • Hyaluronan synthases: a decade-plus of novel glycosyltransferases
    • COI: 1:CAS:528:DC%2BD2sXhsVamur%2FP, PID: 17981795
    • Weigel PH, Deangelis PL (2007) Hyaluronan synthases: a decade-plus of novel glycosyltransferases. J Biol Chem 282:36777–36781
    • (2007) J Biol Chem , vol.282 , pp. 36777-36781
    • Weigel, P.H.1    Deangelis, P.L.2
  • 52
    • 0032080068 scopus 로고    scopus 로고
    • The hyaluronan receptor RHAMM regulates extracellular-regulated kinase
    • COI: 1:CAS:528:DyaK1cXjtFGrsrk%3D, PID: 9556628
    • Zhang S, Chang M, Zylka D, Turley S, Harrison R, Turley E (1998) The hyaluronan receptor RHAMM regulates extracellular-regulated kinase. J Biol Chem 273:11342–11348
    • (1998) J Biol Chem , vol.273 , pp. 11342-11348
    • Zhang, S.1    Chang, M.2    Zylka, D.3    Turley, S.4    Harrison, R.5    Turley, E.6
  • 53
    • 84881477614 scopus 로고    scopus 로고
    • Hyaluronan up-regulates growth and invasion of trophoblasts in an autocrine manner via PI3K/AKT and MAPK/ERK1/2 pathways in early human pregnancy
    • COI: 1:CAS:528:DC%2BC3sXhtVSls7fM, PID: 23806178
    • Zhu R, Huang YH, Tao Y, Wang SC, Sun C, Piao HL, Wang XQ, Du MR, Li DJ (2013) Hyaluronan up-regulates growth and invasion of trophoblasts in an autocrine manner via PI3K/AKT and MAPK/ERK1/2 pathways in early human pregnancy. Placenta 34:784–791
    • (2013) Placenta , vol.34 , pp. 784-791
    • Zhu, R.1    Huang, Y.H.2    Tao, Y.3    Wang, S.C.4    Sun, C.5    Piao, H.L.6    Wang, X.Q.7    Du, M.R.8    Li, D.J.9
  • 54
    • 84934277764 scopus 로고    scopus 로고
    • CD44, hyaluronan, the hematopoietic stem cell, and leukemia-initiating cells frontiers
    • Zoller M (2015) CD44, hyaluronan, the hematopoietic stem cell, and leukemia-initiating cells frontiers. Immunology 6:235
    • (2015) Immunology , vol.6 , pp. 235
    • Zoller, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.