HLA-G immunoreactivity is specific for intermediate trophoblast in gestational trophoblastic disease and can serve as a useful marker in differential diagnosis

American Journal of Surgical Pathology

Volumn 26, Issue 7, 2002, Pages 914-920

  Singer, Gad ^a   Kurman, Robert J ^a   McMaster, Michael T ^b   Shih, Ie Ming ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

Diagnosis; HLA G; Trophoblast

Indexed keywords

CELL MARKER; HLA G ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MONOCLONAL ANTIBODY;

ARTICLE; CHORIOCARCINOMA; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PLACENTA DISORDER; PREGNANCY COMPLICATION; TISSUE DISTRIBUTION; TROPHOBLAST; TROPHOBLASTIC DISEASE; TROPHOBLASTIC TUMOR; TUMOR CLASSIFICATION;

ANTIBODIES; DIAGNOSIS, DIFFERENTIAL; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; IMMUNOHISTOCHEMISTRY; PREGNANCY; TROPHOBLASTIC NEOPLASMS; TROPHOBLASTS; TUMOR MARKERS, BIOLOGICAL; UTERINE NEOPLASMS;

EID: 0036304571     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-200207000-00010     Document Type: Article

References (24)

1. Reaction patterns of monoclonal antibodies to HLA-G in human tissues and on cell lines: A comparative study
2. HLA-G expression by tumors
3. A study of human leukocyte antigen G expression in hydatidiform moles
4. Tumor-specific up-regulation of the nonclassical class I HLA-G antigen expression in renal carcinoma
5. HLA-G isoforms produced by placental cytotrophoblasts and found in amniotic fluid are due to unusual glycosylation
6. HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance
7. Expression of the nonclassical HLA-G antigen in tumor cell lines is extremely restricted
8. HLA-G expression in trophoblast cells is independent of embryonic development
9. Expression of HLA G in human tumors is not a frequent event
10. Placental site nodules and plaques: A clinicopathologic and immunohistochemical study of 25 cases with ultrastructural findings
11. Expression of melanoma cell adhesion molecule in intermediate trophoblast
12. Immunohistochemical localization of inhibin-alpha in the placenta and gestational trophoblastic lesions
13. Epithelioid trophoblastic tumor: A neoplasm distinct from choriocarcinoma and placental site trophoblastic tumor simulating carcinoma
14. The pathology of intermediate trophoblastic tumors and tumor-like lesions
15. Gestational trophoblastic disease
16. Gestational trophoblastic disease
17. Placental site nodule and characterization of distinctive types of intermediate trophoblast
18. Diagnostic and biologic implications of mel-CAM expression in mesenchymal neoplasms
19. The placental site nodule: An immunohistochemical study
20. Human leukocyte antigen G up-regulation in lung cancer associates with high-grade histology, human leukocyte antigen class I loss and interleukin-10 production
21. HLA-G polymorphisms and molecule function: Questions and more questions - A review
22. Vacuolated cytotrophoblast: A subpopulation of trophoblast in the chorion laeve
23. Intermediate trophoblast: Further immunocytochemical characterization
24. Placental site nodules and plaques: A clinicopathologic analysis of 20 cases