Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis

Oncotarget

Volumn 8, Issue 13, 2017, Pages 20543-20557

  Dela Cruz, Mart ^a   Ledbetter, Sarah ^a   Chowdhury, Sanjib ^a   Tiwari, Ashish K ^a   Momi, Navneet ^a   Wali, Ramesh K ^a   Bliss, Charles ^a   Huang, Christopher ^a   Lichtenstein, David ^a   Bhattacharya, Swati ^a   Varma Wilson, Anisha ^a   Backman, Vadim ^b   Roy, Hemant K ^a  

^a BOSTON UNIVERSITY MEDICAL CENTER   (United States)

^b Northwestern University   (United States)

Author keywords

Colorectal carcinoma; Field carcinogenesis; Metabolic reprogramming; Metabolism; Warburg effect

Indexed keywords

GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LACTATE DEHYDROGENASE; MITOCHONDRIAL DNA; PYRUVATE KINASE; PYRUVATE KINASE M2; UNCLASSIFIED DRUG; TRANSCRIPTOME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER SCREENING; COLON CARCINOGENESIS; COLON MUCOSA; COLONOSCOPY; COLORECTAL CANCER; CONTROLLED STUDY; DRP1 GENE; GENE DOSAGE; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MITOCHONDRIAL BIOGENESIS; MITOCHONDRIAL DYNAMICS; NONHUMAN; NUCLEAR REPROGRAMMING; ONCOGENE; OPA1 GENE; OXIDATIVE PHOSPHORYLATION UNCOUPLING; PGC1 ALPHA GENE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; RECTUM BIOPSY; RECTUM MUCOSA; UCP2 GENE; VALIDATION STUDY; ANIMAL; CELL TRANSFORMATION; COLORECTAL TUMOR; IMMUNOHISTOCHEMISTRY; INTESTINE MUCOSA; METABOLISM; PATHOLOGY; PRECANCER;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; PRECANCEROUS CONDITIONS; RATS; REAL-TIME POLYMERASE CHAIN REACTION; TRANSCRIPTOME;

EID: 85016434360     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.16129     Document Type: Article

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