Mitochondria and tumor progression in ulcerative colitis

Journal of the National Cancer Institute

Volumn 105, Issue 16, 2013, Pages 1239-1248

  Ussakli, Cigdem Himmetoglu ^a   Ebaee, Anoosheh ^a   Binkley, Jennifer ^a   Brentnall, Teresa A ^b   Emond, Mary J ^a   Rabinovitch, Peter S ^a,c   Risques, Rosa Ana ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Division of Gastroenterology and Nutrition   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA;

ADULT; AGED; ARTICLE; BIOGENESIS; CANCER PATIENT; CARCINOGENESIS; CLINICAL ARTICLE; COLON BIOPSY; COLON CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GASTROINTESTINAL DYSPLASIA; GENE DOSAGE; GLYCOLYSIS; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; MITOCHONDRION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RESPIRATORY CHAIN; TELOMERE SHORTENING; TUMOR BIOPSY; TUMOR GROWTH; ULCERATIVE COLITIS;

ADULT; AGED; CASE-CONTROL STUDIES; CELL TRANSFORMATION, NEOPLASTIC; COLITIS, ULCERATIVE; COLORECTAL NEOPLASMS; DISEASE PROGRESSION; DNA COPY NUMBER VARIATIONS; ELECTRON TRANSPORT COMPLEX IV; FEMALE; GLYCOLYSIS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MIDDLE AGED; MITOCHONDRIA; POLYMERASE CHAIN REACTION; PRECANCEROUS CONDITIONS; TELOMERE SHORTENING; TRANSCRIPTION FACTORS;

EID: 84883151825     PISSN: 00278874     EISSN: 14602105     Source Type: Journal    
DOI: 10.1093/jnci/djt167     Document Type: Article

References (30)

1. Chatterjee A, Dasgupta S, Sidransky D. Mitochondrial subversion in cancer. Cancer Prev Res (Phila). 2011;4(5):638-654.
2. Yu M. Somatic mitochondrial DNA mutations in human cancers. Adv Clin Chem. 2012;57:99-138.
3. Warburg O. On the origin of cancer cells. Science. 1956;123(3191):309- 314.
4. Ward PS, Thompson CB. Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell. 2012;21(3):297-308.
5. Taylor RW, Barron MJ, Borthwick GM, et al. Mitochondrial DNA mutations in human colonic crypt stem cells. J Clin Invest. 2003;112(9):1351-1360.
6. Greaves LC, Preston SL, Tadrous PJ, et al. Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission. Proc Natl Acad Sci USA. 2006;103(3):714-719.
7. Bernstein C, Facista A, Nguyen H, et al. Cancer and age related colonic crypt deficiencies in cytochrome c oxidase I. World J Gastrointest Oncol. 2010;2(12):429-442.
8. Payne CM, Holubec H, Bernstein C, et al. Crypt-restricted loss and decreased protein expression of cytochrome C oxidase subunit I as potential hypothesis-driven biomarkers of colon cancer risk. Cancer Epidemiol Biomarkers Prev. 2005;14(9):2066-2075.
9. Brentnall TA, Crispin DA, Rabinovitch PS, et al. Mutations in the p53 gene: an early marker of neoplastic progression in ulcerative colitis. Gastroenterology. 1994;107(2):369-378.
10. Burmer GC, Rabinovitch PS, Haggitt RC, et al. Neoplastic progression in ulcerative colitis: histology, DNA content, and loss of a p53 allele. Gastroenterology. 1992;103(5):1602-1610.
11. Rabinovitch PS, Dziadon S, Brentnall TA, et al. Pancolonic chromosomal instability precedes dysplasia and cancer in ulcerative colitis. Cancer Res. 1999;59(20):5148-5153.
12. Risques RA, Lai LA, Himmetoglu C, et al. Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation. Cancer Res. 2011;71(5):1669-1679.
13. Roessner A, Kuester D, Malfertheiner P, et al. Oxidative stress in ulcerative colitis-associated carcinogenesis. Pathol Res Pract. 2008;204(7):511-524.
14. Santhanam S, Rajamanickam S, Motamarry A, et al. Mitochondrial electron transport chain complex dysfunction in the colonic mucosa in ulcera-tive colitis. Inflamm Bowel Dis. 2012;18(11):2158-2168.
15. Santhanam S, Venkatraman A, Ramakrishna BS. Impairment of mitochon-drial acetoacetyl CoA thiolase activity in the colonic mucosa of patients with ulcerative colitis. Gut. 2007;56(11):1543-1549.
16. Sifroni KG, Damiani CR, Stoffel C, et al. Mitochondrial respiratory chain in the colonic mucosal of patients with ulcerative colitis. Mol Cell Biochem. 2010;342(1-2):111-115.
17. Brentnall TA, Pan S, Bronner MP, et al. Proteins that underlie neoplastic progression of ulcerative colitis. Proteomics Clin Appl. 2009;3(11):1326.
18. Hsieh SY, Shih TC, Yeh CY, et al. Comparative proteomic studies on the pathogenesis of human ulcerative colitis. Proteomics. 2006;6(19):5322-5331.
19. May D, Pan S, Crispin DA, et al. Investigating neoplastic progression of ulcerative colitis with label-free comparative proteomics. J Proteome Res. 2011;10(1):200-209.
20. O'Sullivan JN, Bronner MP, Brentnall TA, et al. Chromosomal instability in ulcerative colitis is related to telomere shortening. Nat Genet. 2002;32(2):280-284.
21. O'Sullivan JN, Finley JC, Risques RA, et al. Telomere length assessment in tissue sections by quantitative FISH: image analysis algorithms. Cytometry. 2004;58A(2):120-131.
22. Liang KY, Zeger SL. Longitudinal data analysis using generalized linear models. Biometrika. 1986;73(1):13-22.
23. Osman C, Merkwirth C, Langer T. Prohibitins and the functional com-partmentalization of mitochondrial membranes. J Cell Sci. 2009;122(Pt 21):3823-3830.
24. Zorzano A, Liesa M, Sebastian D, et al. Mitochondrial fusion proteins: dual regulators of morphology and metabolism. Semin Cell Dev Biol. 2010;21(6):566-574.
25. Aquilano K, Vigilanza P, Baldelli S, et al. Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis. J Biol Chem. 2010;285(28):21590-21599.
26. Sahin E, Depinho RA. Linking functional decline of telomeres, mitochondria and stem cells during ageing. Nature. 2010;464(7288):520-528.
27. Dimmer KS, Friedrich B, Lang F, et al. The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells. Biochem J. 2000;350(Pt 1):219-227.
28. Sahin E, Colla S, Liesa M, et al. Telomere dysfunction induces metabolic and mitochondrial compromise. Nature. 2011;470(7334):359-365.
29. Jose C, Bellance N, Rossignol R. Choosing between glycolysis and oxidative phosphorylation: a tumor's dilemma? Biochim Biophys Acta. 2011;1807(6):552-561.
30. Smolkova K, Plecita-Hlavata L, Bellance N, et al. Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells. Int J Biochem Cell Biol. 2011;43(7):950-968.