A novel cycloartane triterpenoid from Cimicifuga induces apoptotic and autophagic cell death in human colon cancer HT-29 cells

Oncology Reports

Volumn 37, Issue 4, 2017, Pages 2079-2086

  Dai, Xiaoli ^a   Liu, Jing ^a   Nian, Yin ^b   Qiu, Ming Hua ^b   Luo, Ying ^a   Zhang, Jihong ^a  

^a KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b KUNMING INSTITUTE OF BOTANY   (China)

Author keywords

Apoptosis; Autophagy; Cimicifuga; Colon cancer cells

Indexed keywords

ANTINEOPLASTIC AGENT; BAFILOMYCIN A1; CASPASE 3; CASPASE 8; CIMICIFUGA RACEMOSA EXTRACT; CIMIGENOL; GREEN FLUORESCENT PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; UNCLASSIFIED DRUG; CYCLOARTANE; TRITERPENE; TUMOR PROTEIN;

ACTAEA; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; BIOACCUMULATION; CANCER INHIBITION; CELL DEATH; CELL STRUCTURE; CIMICIFUGA DAHURICA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STRUCTURE; G2 PHASE CELL CYCLE CHECKPOINT; HT-29 CELL LINE; HUMAN; HUMAN CELL; MTT ASSAY; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; WESTERN BLOTTING; BIOSYNTHESIS; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; COLONIC NEOPLASMS; DRUG EFFECTS; GENE EXPRESSION REGULATION; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CIMICIFUGA; COLONIC NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HT29 CELLS; HUMANS; NEOPLASM PROTEINS; SIGNAL TRANSDUCTION; TRITERPENES;

EID: 85016420769     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2017.5444     Document Type: Article

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