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Volumn 1, Issue 5, 2016, Pages

IL-10 induces a STAT3-dependent autoregulatory loop in TH2 cells that promotes Blimp-1 restriction of cell expansion via antagonism of STAT5 target genes

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EID: 85016317149     PISSN: None     EISSN: 24709468     Source Type: Journal    
DOI: 10.1126/sciimmunol.aaf8612     Document Type: Article
Times cited : (21)

References (41)
  • 2
    • 75649136214 scopus 로고    scopus 로고
    • Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation
    • S. Crotty, R. J. Johnston, S. P. Schoenberger, Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation. Nat. Immunol. 11, 114–120 (2010).
    • (2010) Nat. Immunol. , vol.11 , pp. 114-120
    • Crotty, S.1    Johnston, R.J.2    Schoenberger, S.P.3
  • 6
    • 84861423126 scopus 로고    scopus 로고
    • Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation
    • A. Ballesteros-Tato, B. León, B. A. Graf, A. Moquin, P. S. Adams, F. E. Lund, T. D. Randall, Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation. Immunity 36, 847–856 (2012).
    • (2012) Immunity , vol.36 , pp. 847-856
    • Ballesteros-Tato, A.1    León, B.2    Graf, B.A.3    Moquin, A.4    Adams, P.S.5    Lund, F.E.6    Randall, T.D.7
  • 18
    • 79957629559 scopus 로고    scopus 로고
    • Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population
    • X.-J. Zhou, X.-L. Lu, J.-C. Lv, H.-Z. Yang, L.-X. Qin, M.-H. Zhao, Y. Su, Z.-G. Li, H. Zhang, Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population. Ann. Rheum. Dis. 70, 1330–1337 (2011).
    • (2011) Ann. Rheum. Dis. , vol.70 , pp. 1330-1337
    • Zhou, X.-J.1    Lu, X.-L.2    Lv, J.-C.3    Yang, H.-Z.4    Qin, L.-X.5    Zhao, M.-H.6    Su, Y.7    Li, Z.-G.8    Zhang, H.9
  • 19
    • 84891765853 scopus 로고    scopus 로고
    • Regulatory mechanisms that control T-follicular helper and T-helper 1 cell flexibility
    • A. S. Weinmann, Regulatory mechanisms that control T-follicular helper and T-helper 1 cell flexibility. Immunol. Cell Biol. 92, 34–39 (2014).
    • (2014) Immunol. Cell Biol. , vol.92 , pp. 34-39
    • Weinmann, A.S.1
  • 20
    • 77958611660 scopus 로고    scopus 로고
    • + T-cell differentiation regulated by networks of cytokines and transcription factors
    • + T-cell differentiation regulated by networks of cytokines and transcription factors. Immunol. Rev. 238, 247–262 (2010).
    • (2010) Immunol. Rev. , vol.238 , pp. 247-262
    • Zhu, J.1    Paul, W.E.2
  • 21
    • 51049092937 scopus 로고    scopus 로고
    • Blimp-1 directly represses Il2 and the Il2 activator Fos, attenuating T cell proliferation and survival
    • G. A. Martins, L. Cimmino, J. Liao, E. Magnusdottir, K. Calame, Blimp-1 directly represses Il2 and the Il2 activator Fos, attenuating T cell proliferation and survival. J. Exp. Med. 205, 1959–1965 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 1959-1965
    • Martins, G.A.1    Cimmino, L.2    Liao, J.3    Magnusdottir, E.4    Calame, K.5
  • 22
    • 33845958028 scopus 로고    scopus 로고
    • Cytokine-dependent Blimp-1 expression in activated T cells inhibits IL-2 production
    • D. Gong, T. R. Malek, Cytokine-dependent Blimp-1 expression in activated T cells inhibits IL-2 production. J. Immunol. 178, 242–252 (2007).
    • (2007) J. Immunol. , vol.178 , pp. 242-252
    • Gong, D.1    Malek, T.R.2
  • 24
    • 0027260963 scopus 로고
    • Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni
    • T. A. Wynn, I. Eltoum, A. W. Cheever, F. A. Lewis, W. C. Gause, A. Sher, Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni. J. Immunol. 151, 1430–1440 (1993).
    • (1993) J. Immunol. , vol.151 , pp. 1430-1440
    • Wynn, T.A.1    Eltoum, I.2    Cheever, A.W.3    Lewis, F.A.4    Gause, W.C.5    Sher, A.6
  • 25
    • 0026562075 scopus 로고
    • CD4+ Th2 response induced by Schistosoma mansoni eggs develops rapidly, through an early, transient, Th0-like stage
    • A. T. Vella, E. J. Pearce, CD4+ Th2 response induced by Schistosoma mansoni eggs develops rapidly, through an early, transient, Th0-like stage. J. Immunol. 148, 2283–2290 (1992).
    • (1992) J. Immunol. , vol.148 , pp. 2283-2290
    • Vella, A.T.1    Pearce, E.J.2
  • 26
    • 0025186453 scopus 로고
    • Isolation of monoclonal antibodies specific for IL-4, IL-5, IL-6, and a new Th2-specific cytokine (IL-10), cytokine synthesis inhibitory factor, by using a solid phase radioimmunoadsorbent assay
    • T. R. Mosmann, J. H. Schumacher, D. F. Fiorentino, J. Leverah, K. W. Moore, M. W. Bond, Isolation of monoclonal antibodies specific for IL-4, IL-5, IL-6, and a new Th2-specific cytokine (IL-10), cytokine synthesis inhibitory factor, by using a solid phase radioimmunoadsorbent assay. J. Immunol. 145, 2938–2945 (1990).
    • (1990) J. Immunol. , vol.145 , pp. 2938-2945
    • Mosmann, T.R.1    Schumacher, J.H.2    Fiorentino, D.F.3    Leverah, J.4    Moore, K.W.5    Bond, M.W.6
  • 27
    • 0029981103 scopus 로고    scopus 로고
    • Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain
    • R. M. Weber-Nordt, J. K. Riley, A. C. Greenlund, K. W. Moore, J. E. Darnell, R. D. Schreiber, Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain. J. Biol. Chem. 271, 27954–27961 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 27954-27961
    • Weber-Nordt, R.M.1    Riley, J.K.2    Greenlund, A.C.3    Moore, K.W.4    Darnell, J.E.5    Schreiber, R.D.6
  • 28
    • 0030573991 scopus 로고    scopus 로고
    • IL-10 induces DNA binding activity of three STAT proteins (Stat1, Stat3, and Stat5) and their distinct combinatorial assembly in the promoters of selected genes
    • J. Wehinger, F. Gouilleux, B. Groner, J. Finke, R. Mertelsmann, R. M. Weber-Nordt, IL-10 induces DNA binding activity of three STAT proteins (Stat1, Stat3, and Stat5) and their distinct combinatorial assembly in the promoters of selected genes. FEBS Lett. 394, 365–370 (1996).
    • (1996) FEBS Lett , vol.394 , pp. 365-370
    • Wehinger, J.1    Gouilleux, F.2    Groner, B.3    Finke, J.4    Mertelsmann, R.5    Weber-Nordt, R.M.6
  • 34
    • 79952637807 scopus 로고    scopus 로고
    • IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation
    • D. Eto, C. Lao, D. DiToro, B. Barnett, T. C. Escobar, R. Kageyama, I. Yusuf, S. Crotty, IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation. PLOS ONE 6, e17739 (2011).
    • (2011) PLOS ONE , vol.6
    • Eto, D.1    Lao, C.2    DiToro, D.3    Barnett, B.4    Escobar, T.C.5    Kageyama, R.6    Yusuf, I.7    Crotty, S.8
  • 35
    • 84896372779 scopus 로고    scopus 로고
    • Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells
    • J. P. Ray, H. D. Marshall, B. J. Laidlaw, M. M. Staron, S. M. Kaech, J. Craft, Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells. Immunity 40, 367–377 (2014).
    • (2014) Immunity , vol.40 , pp. 367-377
    • Ray, J.P.1    Marshall, H.D.2    Laidlaw, B.J.3    Staron, M.M.4    Kaech, S.M.5    Craft, J.6
  • 37
    • 0030024563 scopus 로고    scopus 로고
    • Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
    • J. E. Durbin, R. Hackenmiller, M. C. Simon, D. E. Levy, Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 84, 443–450 (1996).
    • (1996) Cell , vol.84 , pp. 443-450
    • Durbin, J.E.1    Hackenmiller, R.2    Simon, M.C.3    Levy, D.E.4
  • 40
    • 84895806505 scopus 로고    scopus 로고
    • Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression
    • W. Liao, R. Spolski, P. Li, N. Du, E. E. West, M. Ren, S. Mitra, W. J. Leonard, Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression. Proc. Natl. Acad. Sci. U.S.A. 111, 3508–3513 (2014).
    • (2014) Proc. Natl. Acad. Sci. U.S.A. , vol.111 , pp. 3508-3513
    • Liao, W.1    Spolski, R.2    Li, P.3    Du, N.4    West, E.E.5    Ren, M.6    Mitra, S.7    Leonard, W.J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.