Sex-specific, reciprocal regulation of ERα and miR-22 controls muscle lipid metabolism in male mice

EMBO Journal

Volumn 36, Issue 9, 2017, Pages 1199-1214

  Schweisgut, Judith ^a   Schutt, Christian ^a   Wüst, Stas ^a   Wietelmann, Astrid ^a   Ghesquière, Bart ^b   Carmeliet, Peter ^b,c   Dröse, Stefan ^d   Korach, Kenneth S ^e   Braun, Thomas ^a   Boettger, Thomas ^a  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c Vesalius Research Center   (Belgium)

^d UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^e Laboratory of Reproductive and Developmental Toxicology   (United States)

Author keywords

ER ; miR 22; miRNA processing; muscle lipid metabolism; sexual dimorphism

Indexed keywords

BETA GALACTOSIDASE; CARNITINE PALMITOYLTRANSFERASE I; ESTROGEN RECEPTOR ALPHA; FATTY ACID; GENOMIC DNA; LEPTIN; LONG UNTRANSLATED RNA; MICRORNA 22; TRANSCRIPTOME; MICRORNA; MIRN22 MICRORNA, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; BODY COMPOSITION; BODY WEIGHT; CONTROLLED STUDY; ENERGY BALANCE; EXON; FATTY ACID OXIDATION; FEEDBACK SYSTEM; FEMALE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HEART STRESS; HEK293 CELL LINE; HUMAN; HUMAN CELL; IN VIVO STUDY; LIPID METABOLISM; LOCOMOTION; LUCIFERASE ASSAY; LUNG GAS EXCHANGE; MALE; MALIGNANT NEOPLASM; MOUSE; MUSCLE MASS; MUSCLE METABOLISM; MYOBLAST; NEGATIVE FEEDBACK; NONHUMAN; NORTHERN BLOTTING; PANCREAS ISLET; PRECURSOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECONDARY STRUCTURE; REGULATORY MECHANISM; RNA PROCESSING; SEX DIFFERENCE; SKELETAL MUSCLE; TRIACYLGLYCEROL BLOOD LEVEL; WESTERN BLOTTING; WHITE ADIPOSE TISSUE; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION REGULATION; METABOLISM; MUSCLE;

ANIMALS; ESTROGEN RECEPTOR ALPHA; GENE EXPRESSION REGULATION; LIPID METABOLISM; MALE; MICE; MICRORNAS; MUSCLES; SEX FACTORS;

EID: 85016301687     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201695988     Document Type: Article

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