Immunogenicity and efficacy of a DNA vaccine encoding a human anti-idiotype single chain antibody against nasopharyngeal carcinoma

Vaccine

Volumn 28, Issue 15, 2010, Pages 2769-2774

  Luo, Chen ^a   Wang, Jia Jia ^a   Li, Yue Hui ^a   Hu, Jin Yue ^a   Li, Guan Cheng ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Anti idiotype antibody; DNA immunity; Nasopharyngeal carcinoma; Vaccine

Indexed keywords

ANTIIDIOTYPIC ANTIBODY; ANTIIDIOTYPIC ANTIBODY G22; DNA VACCINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; FEMALE; HUMORAL IMMUNITY; IMMUNOCYTOCHEMISTRY; IMMUNOGENICITY; MOLECULAR CLONING; MOUSE; NASOPHARYNX CARCINOMA; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; TUMOR VOLUME;

ANIMALS; ANTIBODIES; CANCER VACCINES; CARCINOMA; FEMALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NASOPHARYNGEAL NEOPLASMS; SINGLE-CHAIN ANTIBODIES; SURVIVAL ANALYSIS; T-LYMPHOCYTES; VACCINES, DNA;

EID: 77649239189     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.01.033     Document Type: Article

References (33)

1. Yu M.C., and Yuan J.M. Epidemiology of nasopharyngeal carcinoma. Semin Cancer Biol 12 6 (2002) 421-429
2. Chan A.T.C., Teo P.M.L., and Johnson P.J. Nasopharyngeal carcinoma. Ann Oncol 13 7 (2002) 1007-1015
3. Baral R., Sherrat A., Das R., Foon K.A., and Bhattacharya-Chatterjee M. Murine monoclonal anti-idiotypic antibody as a surrogate antigen for human Her-2/neu. Int J Cancer 92 1 (2001) 88-95
4. Spendlove L., Li L., Potter V., Christiansen D., Loveland B.E., and Durrant L.G. A therapeutic human anti-idiotypic antibody mimics CD55 in three distinct regions. Eur J Immunol 30 10 (2000) 2944-2953
5. Li G.C., Zhu J.G., Zhou G.H., and Sun Q.B. Induction of humoral and cellular immune responses with anti-idiotypic antibody for nasopharyngeal carcinoma. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 16 2 (2000) 134-137
6. Syrengelas A.D., and Levy R. DNA vaccination against the idiotype of a murine B cell lymphoma: mechanism of tumor protection. J Immunol 162 8 (1999) 4790-4795
7. Zbar A.P., Thomas H., Wilkinson R.W., Wadhwa M., Syrigos K.N., Ross E.L., et al. Immune responses in advanced colorectal cancer following repeated intradermal vaccination with the anti-CEA murine monoclonal antibody, PR1A3: results of a phase I study. Int J Colorectal Dis 20 5 (2005) 403-414
8. Chen S., Li B., Xie H., Xu L., Niu G., Fan K., et al. Phase I clinical trial of targeted therapy using 131I-Hepama-1 mAb in patients with hepatocellular carcinoma. Cancer Biother Radiopharm 19 5 (2004) 589-600
9. Otsuji E., Tsuruta H., Toma A., Kobayashi S., Okamoto K., Yata Y., et al. Effects of idiotypic human anti-mouse antibody against in vitro binding and antitumor activity of a monoclonal antibody-drug conjugate. Hepatogastroenterology 50 50 (2003) 380-384
10. Zhu H., Yang B., Yang X., Wang L., Xu J., Liao C., et al. A novel antibody fragment targeting HAb18G/CD147 with cytotoxicity and decreased immunogenicity. Cancer Biol Ther 8 11 (2009) 1035-1044
11. He X.J., Li G.C., Zhu J.G., Li Y.H., and Zhou G.H. Construction and screening of human anti-idiotypic single chain antibodies of nasopharyngeal carcinoma. Ai Zheng 23 2 (2004) 124-129
12. He X.J., Li G.C., Zhu J.G., and Li Y.H. Construction of phage anti-idiotypic antibody library using sensitized in vitro B-lymphocytes of nasopharyngeal cancer patients. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 19 3 (2003) 266-271
13. Luo C., He X.J., Zhao Y., Zhang Z.J., and Li G.C. Construction of eukaryotic expression vector encoding human nasopharyngeal carcinoma anti-idiotype antibody single chain fragment gene G22 and its expression. J Cent South Univ (Med Sci) 33 1 (2008) 16-20
14. Saha A., Chatterjee S.K., Foon K.A., Primus F.J., and Bhattacharya-Chatterjee M. Murine dendritic cells pulsed with an anti-idiotype antibody induce antigen-specific protective antitumor immunity. Cancer Res 63 11 (2003) 2844-2854
15. Seder R.A. Gurunathan S.DNA vaccines-designer vaccines for the 21st century. New Engl J Med 341 4 (1999) 277-278
16. Shedlock D.J., and Shen H. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 300 5617 (2003) 337-339
17. Sun J.C., and Bevan M.J. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 300 5617 (2003) 339-342
18. Saha A., Chatterjee S.K., Foon K.A., and Bhattacharya-Chatterjee M. Anti-idiotype antibody induced cellular immunity in mice transgenic for human carcinoembryonic antigen. Immunology 118 4 (2006) 483-496
19. Li G.C., Zhu J.G., Zhou G.H., and Sun Q.B. Production of mono-clonal antibodies against nasopharyngeal cancer (NPC) by in vivo and vitro combining immunization. Hunan Med J 16 5 (1999) 326-328
20. Wilson N.B. Immunoflurorescene and related staning techniques (1978), Biomedical Press, New York
21. Wang S., Zhang C., Zhang L., Li J., Huang Z., and Lu S. The relative immunogenicity of DNA vaccines delivered by the intramuscular needle injection, electroporation and gene gun methods. Vaccine 26 17 (2008) 2100-2110
22. Moreno A., Brocchi E., Lelli D., Gamba D., Tranquillo M., and Cordioli P. Monoclonal antibody based ELISA tests to detect antibodies against neuraminidase subtypes 1, 2 and 3 of avian influenza viruses in avian sera. Vaccine 27 36 (2009) 4967-4974
23. Coelho M., Gauthier P., Pugnière M., Roquet F., Pèlegrin A., and Navarro-Teulon I. Isolation and characterisation of a human anti-idiotypic scFv used as a surrogate tumour antigen to elicit an anti-HER-2/neu humoral response in mice. Br J Cancer 90 10 (2004) 2032-2041
24. Timmerman J.M., Singh G., Hermanson G., Hobart P., Czerwinski D.K., Taidi B., et al. Immunogenicity of a plasmid DNA vaccine encoding chimeric idiotype in patients with B-cell lymphoma. Cancer Res 62 20 (2002) 5845-5852
25. Mosolits S., Markovic K., Frödin J.E., Virving L., Magnusson C.G., Steinitz M., et al. Vaccination with Ep-CAM protein or anti-idiotypic antibody induces Th1-biased response against MHC Class I- and II-restricted Ep-CAM epitopes in colorectal carcinoma patients. Clin Cancer Res 10 16 (2004) 5391-5402
26. Alfonso M., Díaz A., Hernández A.M., Perez A., Rodriguez E., Bitton R., et al. An anti-idiotype vaccine elicits a specific response to N-glycolyl sialic acid residues of glycoconjugates in melanoma patients. J Immunol 168 5 (2002) 2523-2529
27. Pfisterer J., du Bois A., Sehouli J., Loibl S., Reinartz S., Reuß A., et al. The anti-idiotypic antibody abagovomab in patients with recurrent ovarian cancer. A phase I trial of the AGO-OVAR. Ann Oncol 17 10 (2006) 1568-1577
28. Hernández A.M., Toledo D., Martínez D., Grinan T., Brito V., Macias A., et al. Characterization of the antibody response against NeuGcGM3 ganglioside elicited in non-small cell lung cancer patients immunized with an anti-idiotype antibody. J. Immunol 181 9 (2008) 6625-6634
29. Li G.C., Xie L., Zhou G.H., Fu H.P., Zhou J.H., and Sun Q.B. A clinical trial of active immunotherapy with anti-idiotypic vaccine in nasopharyngeal carcinoma patients. Chin Med J 115 4 (2002) 567-570
30. Janssen E.M., Lemmens E.E., Wolfe T., Christen U., von Herrath M.G., and Schoenberger S.P. CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes. Nature 421 6925 (2003) 852-856
31. Snyder L.A., Goletz T.J., Gunn G.R., Shi F.F., Harris M.C., Cochlin K., et al. A MUC1/IL-18 DNA vaccine induces anti-tumor immunity and increased survival in MUC1 transgenic mice. Vaccine 24 16 (2006) 3340-3352
32. Shi F.F., Gunn G.R., and Snyder L.A. Intradermal vaccination of MUC1 transgenic mice with MUC1/IL-18 plasmid DNA suppresses experimental pulmonary metastases. Vaccine 25 17 (2007) 3338-3346
33. Morisaki T., Morton D.L., Uchiyama A., Yuzuki D., Barth A., and Hoon D.S. Characterization and augmentation of CD4+ cytotoxic T cell lines against melanoma. Cancer Immunol Immunother 39 3 (1994) 172-178