-
1
-
-
77449099985
-
Molecular neuropathology of low-grade gliomas and its clinical impact
-
Riemenschneider, M. J. & Reifenberger, G. Molecular neuropathology of low-grade gliomas and its clinical impact. Adv Tech Stand Neurosurg. 35, 35-64 (2010).
-
(2010)
Adv Tech Stand Neurosurg.
, vol.35
, pp. 35-64
-
-
Riemenschneider, M.J.1
Reifenberger, G.2
-
2
-
-
85015483774
-
Current trends in the surgical management and treatment of adult glioblastoma
-
Young, R. M., Jamshidi, A., Davis, G. & Sherman, J. H. Current trends in the surgical management and treatment of adult glioblastoma. Ann Transl Med. 3, 121 (2015).
-
(2015)
Ann Transl Med.
, vol.3
, pp. 121
-
-
Young, R.M.1
Jamshidi, A.2
Davis, G.3
Sherman, J.H.4
-
3
-
-
84942501073
-
Survival and low-grade glioma: The emergence of genetic information
-
Claus, E. B. et al. Survival and low-grade glioma: the emergence of genetic information. Neurosurg Focus. 38, E6 (2015).
-
(2015)
Neurosurg Focus.
, vol.38
, pp. E6
-
-
Claus, E.B.1
-
4
-
-
33745653513
-
Low-grade gliomas in adults
-
Grier, J. T. & Batchelor, T. Low-grade gliomas in adults. Oncologist. 11, 681-693 (2006).
-
(2006)
Oncologist.
, vol.11
, pp. 681-693
-
-
Grier, J.T.1
Batchelor, T.2
-
5
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan, H. et al. IDH1 and IDH2 mutations in gliomas. N Engl J Med. 360, 765-73 (2009).
-
(2009)
N Engl J Med.
, vol.360
, pp. 765-773
-
-
Yan, H.1
-
6
-
-
84945162385
-
IDH mutation, 1p19q codeletion and ATRX loss in WHO grade II gliomas
-
Leeper, H. E. et al. IDH mutation, 1p19q codeletion and ATRX loss in WHO grade II gliomas. Oncotarget. 6, 30295-305 (2015).
-
(2015)
Oncotarget.
, vol.6
, pp. 30295-30305
-
-
Leeper, H.E.1
-
7
-
-
84877632013
-
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
-
Rohle, D. et al. An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells. Science. 340, 626-630 (2013).
-
(2013)
Science
, vol.340
, pp. 626-630
-
-
Rohle, D.1
-
8
-
-
84886744421
-
Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine
-
Turcan, S. et al. Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine. Oncotarget. 4, 1729-36 (2013).
-
(2013)
Oncotarget
, vol.4
, pp. 1729-1736
-
-
Turcan, S.1
-
9
-
-
78649990315
-
Cancer-associated IDH mutations: Biomarker and therapeutic opportunities
-
Yen, K. E., Bittinger, M. A., Su, S. M. & Fantin, V. R. Cancer-associated IDH mutations: biomarker and therapeutic opportunities. Oncogene. 29, 6409-17 (2010).
-
(2010)
Oncogene
, vol.29
, pp. 6409-6417
-
-
Yen, K.E.1
Bittinger, M.A.2
Su, S.M.3
Fantin, V.R.4
-
10
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
Dang, L. et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 462, 739-744 (2009).
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
-
11
-
-
84858796263
-
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
-
Turcan, S. et al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature. 483, 479-83 (2012).
-
(2012)
Nature
, vol.483
, pp. 479-483
-
-
Turcan, S.1
-
12
-
-
33745315198
-
Nuclear magnetic resonance spectra from a crystal rotated at high speed
-
Andrew, E. R., Bradbury, A. & Eades, R. G. Nuclear magnetic resonance spectra from a crystal rotated at high speed. Nature 182, 1659 (1958).
-
(1958)
Nature
, vol.182
, pp. 1659
-
-
Andrew, E.R.1
Bradbury, A.2
Eades, R.G.3
-
13
-
-
84897960611
-
Characterization of metabolites in infiltrating gliomas using ex vivo H high-resolution magic angle spinning spectroscopy
-
Elkhaled, A. et al. Characterization of metabolites in infiltrating gliomas using ex vivo H high-resolution magic angle spinning spectroscopy. NMR Biomed. 27, 578-93 (2014).
-
(2014)
NMR Biomed.
, vol.27
, pp. 578-593
-
-
Elkhaled, A.1
-
14
-
-
51449121886
-
Evaluation of lactate and alanine as metabolic biomarkers of prostate cancer using 1H HR-MAS spectroscopy of biopsy tissues
-
Tessem, M. B. et al. Evaluation of lactate and alanine as metabolic biomarkers of prostate cancer using 1H HR-MAS spectroscopy of biopsy tissues. Magn Reson Med. 60, 510-6 (2008).
-
(2008)
Magn Reson Med.
, vol.60
, pp. 510-516
-
-
Tessem, M.B.1
-
15
-
-
84982187318
-
Magnetic resonance analysis of malignant transformation in recurrent glioma
-
Jalbert, L. E. et al. Magnetic resonance analysis of malignant transformation in recurrent glioma. Neuro-Oncology Advanced electronic publication, doi: 10.1093/neuonc/now008 (2016).
-
(2016)
Neuro-Oncology Advanced Electronic Publication
-
-
Jalbert, L.E.1
-
16
-
-
0030162959
-
Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI
-
Basser, P. J. & Pierpaoli, C. Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. J Magn Reson. 111, 209-19 (1996).
-
(1996)
J Magn Reson.
, vol.111
, pp. 209-219
-
-
Basser, P.J.1
Pierpaoli, C.2
-
17
-
-
85016050029
-
VTK CISG Registration Toolkit: An open source software package for affine and non-rigid registration of single-and multimodal 3D images
-
Germany Springer-Verlag
-
Hartkens, T., Rueckert, D., Schnabel, J. A., Hawkes, D. J. & Hill, D. L. G. VTK CISG Registration Toolkit: An open source software package for affine and non-rigid registration of single-and multimodal 3D images. BVM Leipzig, Germany, Springer-Verlag 185 (2012).
-
(2012)
BVM Leipzig
, vol.185
-
-
Hartkens, T.1
Rueckert, D.2
Schnabel, J.A.3
Hawkes, D.J.4
Hill, D.L.G.5
-
18
-
-
20044384204
-
Dynamic susceptibility contrast perfusion imaging of radiation effects in normalappearing brain tissue: Changes in the first-pass and recirculation phases
-
Lee, M. C., Cha, S., Chang, S. M. & Nelson, S. J. Dynamic susceptibility contrast perfusion imaging of radiation effects in normalappearing brain tissue: changes in the first-pass and recirculation phases. J Magn Reson Imaging. 21, 683-93 (2005).
-
(2005)
J Magn Reson Imaging.
, vol.21
, pp. 683-693
-
-
Lee, M.C.1
Cha, S.2
Chang, S.M.3
Nelson, S.J.4
-
19
-
-
27944474903
-
Dynamic susceptibility weighted perfusion imaging of high-grade gliomas: Characterization of spatial heterogeneity
-
Lupo, J. M., Cha, S., Chang, S. M. & Nelson, S. J. Dynamic susceptibility weighted perfusion imaging of high-grade gliomas: characterization of spatial heterogeneity. Am J Neuroradiol. 26, 1446-54 (2005).
-
(2005)
Am J Neuroradiol.
, vol.26
, pp. 1446-1454
-
-
Lupo, J.M.1
Cha, S.2
Chang, S.M.3
Nelson, S.J.4
-
20
-
-
84877100892
-
Survival analysis in patients with newly diagnosed glioblastoma using pre-and postradiotherapy MR spectroscopic imaging
-
Li, Y. et al. Survival analysis in patients with newly diagnosed glioblastoma using pre-and postradiotherapy MR spectroscopic imaging. J Neurooncol. 15, 607-617 (2013).
-
(2013)
J Neurooncol.
, vol.15
, pp. 607-617
-
-
Li, Y.1
-
21
-
-
84881398824
-
SIVIC: Open-source, standards-based software for DICOM MR spectroscopy workflows
-
Crane, J. C., Olson, M. P. & Nelson, S. J. SIVIC: Open-Source, Standards-Based Software for DICOM MR Spectroscopy Workflows. Int J Biomed Imaging 2013, 169526-12 (2013).
-
(2013)
Int J Biomed Imaging
, vol.2013
, pp. 169526-169612
-
-
Crane, J.C.1
Olson, M.P.2
Nelson, S.J.3
-
22
-
-
0002899752
-
Modified spin-echo method for measuring nuclear relaxation times
-
Meiboom, S. & Gill, D. Modified spin-echo method for measuring nuclear relaxation times. Rev Sci Instrum. 29, 688-691 (1958).
-
(1958)
Rev Sci Instrum.
, vol.29
, pp. 688-691
-
-
Meiboom, S.1
Gill, D.2
-
23
-
-
70449518400
-
Monoclonal antibody specific for IDH1 R132H mutation
-
Capper, D., Zentgraf, H., Balss, J., Hartmann, C. & Von Deimling, A. Monoclonal antibody specific for IDH1 R132H mutation. Acta Neuropathol. 118, 599-601 (2009).
-
(2009)
Acta Neuropathol.
, vol.118
, pp. 599-601
-
-
Capper, D.1
Zentgraf, H.2
Balss, J.3
Hartmann, C.4
Von Deimling, A.5
-
24
-
-
78650283281
-
Semi-parametric time-domain quantification of HR-MAS data from prostate tissue
-
Ratiney, H., Albers, M. J., Rabeson, H. & Kurhanewicz, J. Semi-parametric time-domain quantification of HR-MAS data from prostate tissue. NMR Biomed. 23, 1146-1157 (2010).
-
(2010)
NMR Biomed.
, vol.23
, pp. 1146-1157
-
-
Ratiney, H.1
Albers, M.J.2
Rabeson, H.3
Kurhanewicz, J.4
-
25
-
-
79955934629
-
Gitools analysis and visualisation of genomic data using interactive heat-maps
-
Perez-Llamas, C. & Lopez-Bigas, N. Gitools: Analysis and Visualisation of Genomic Data Using Interactive Heat-Maps. PLoS ONE. 6, e19541 (2011).
-
(2011)
PLoS ONE.
, vol.6
, pp. e19541
-
-
Perez-Llamas, C.1
Lopez-Bigas, N.2
-
26
-
-
79960858482
-
Metabolism and brain cancer
-
Marie, S. K. N. & Shinjo, S. M. O. Metabolism and Brain Cancer. Clinics. 66, 33-43 (2011).
-
(2011)
Clinics
, vol.66
, pp. 33-43
-
-
Marie, S.K.N.1
Shinjo, S.M.O.2
-
27
-
-
84904093345
-
Hyperpolarized 1-13C glutamate: A metabolic imaging biomarker of IDH1-mutation status in glioma
-
Chaumeil, M. M. et al. Hyperpolarized 1-13C glutamate: a metabolic imaging biomarker of IDH1-mutation status in glioma. Cancer Res. 74, 4247-57 (2014).
-
(2014)
Cancer Res.
, vol.74
, pp. 4247-4257
-
-
Chaumeil, M.M.1
-
28
-
-
84897222558
-
Non-invasive in vivo assessment of IDH1 mutational status in glioma
-
Chaumeil, M. M. et al. Non-invasive in vivo assessment of IDH1 mutational status in glioma. Nat Comm. 4, 2429 (2013).
-
(2013)
Nat Comm.
, vol.4
, pp. 2429
-
-
Chaumeil, M.M.1
-
29
-
-
84918565322
-
Changes in pyruvate metabolism detected by magnetic resonance imaging are linked to DNA damage and serve as a sensor for temozolomide response in glioblastoma cells
-
Park, I. et al. Changes in Pyruvate Metabolism Detected by Magnetic Resonance Imaging Are Linked to DNA Damage and Serve as a Sensor for Temozolomide Response in Glioblastoma Cells. Cancer Res. 74, 7115-7124 (2014).
-
(2014)
Cancer Res.
, vol.74
, pp. 7115-7124
-
-
Park, I.1
-
30
-
-
84858008628
-
The role of glutathione in brain tumor drug resistance
-
Backos, D. S., Franklin, C. C. & Reigan, P. The role of glutathione in brain tumor drug resistance. Biochem Pharmacol. 83, 1005-12 (2012).
-
(2012)
Biochem Pharmacol.
, vol.83
, pp. 1005-1012
-
-
Backos, D.S.1
Franklin, C.C.2
Reigan, P.3
-
31
-
-
79952741730
-
Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome
-
Reitman, Z. J. et al. Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome. Proc Natl Acad Sci USA 108, 3270-3275 (2011).
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 3270-3275
-
-
Reitman, Z.J.1
-
32
-
-
84925536048
-
Decreasing GSH and increasing ROS in chemosensitivity gliomas with IDH1 mutation
-
Shi, J. et al. Decreasing GSH and increasing ROS in chemosensitivity gliomas with IDH1 mutation. Tumor Biol. 36, 655 (2015).
-
(2015)
Tumor Biol.
, vol.36
, pp. 655
-
-
Shi, J.1
-
33
-
-
84869209736
-
The metabolomics signature of malignant glioma reflects accelerated anabolic metabolism
-
Chinnaiyan, P. et al. The metabolomics signature of malignant glioma reflects accelerated anabolic metabolism. Cancer Res. 72, 5878-88 (2012).
-
(2012)
Cancer Res.
, vol.72
, pp. 5878-5888
-
-
Chinnaiyan, P.1
-
34
-
-
84862907969
-
Magnetic resonance of 2-hydroxyglutarate in IDH1-mutated low-grade gliomas
-
Elkhaled, A., Jalbert, L. E. et al. Magnetic resonance of 2-hydroxyglutarate in IDH1-mutated low-grade gliomas. Sci Transl Med. 4, 116ra5 (2012).
-
(2012)
Sci Transl Med.
, vol.4
, pp. 116ra5
-
-
Elkhaled, A.1
Jalbert, L.E.2
-
35
-
-
84855710482
-
Detection of 2-hydroxyglutarate in IDH-mutated glioma patients by in vivo spectral-editing and 2D correlation magnetic resonance spectroscopy
-
Andronesi, O. C. et al. Detection of 2-hydroxyglutarate in IDH-mutated glioma patients by in vivo spectral-editing and 2D correlation magnetic resonance spectroscopy. Sci Transl Med. 4, 116ra4 (2012).
-
(2012)
Sci Transl Med.
, vol.4
, pp. 116ra4
-
-
Andronesi, O.C.1
-
36
-
-
84862776826
-
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas
-
Choi, C. et al. 2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas. Nat Med. 18, 624-9 (2012).
-
(2012)
Nat Med.
, vol.18
, pp. 624-629
-
-
Choi, C.1
-
37
-
-
85012045784
-
Central Role of glutamate metabolism in the maintenance of nitrogen homeostasis in normal and hyperammonemic brain
-
Cooper, A. J. L. & Jeitner, T. M. Central Role of Glutamate Metabolism in the Maintenance of Nitrogen Homeostasis in Normal and Hyperammonemic Brain. Biomolecules. 6, 1-33 (2016).
-
(2016)
Biomolecules
, vol.6
, pp. 1-33
-
-
Cooper, A.J.L.1
Jeitner, T.M.2
-
38
-
-
84858603856
-
Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy
-
Pope, W. B. et al. Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy. Journal of neuro-oncology. 107, 197-205 (2012).
-
(2012)
Journal of Neuro-oncology
, vol.107
, pp. 197-205
-
-
Pope, W.B.1
-
39
-
-
84960430663
-
Integration of 2-hydroxyglutarate-proton magnetic resonance spectroscopy into clinical practice for disease monitoring in isocitrate dehydrogenase-mutant glioma
-
De La Fuente, M. I. et al. Integration of 2-hydroxyglutarate-proton magnetic resonance spectroscopy into clinical practice for disease monitoring in isocitrate dehydrogenase-mutant glioma. Neuro Oncol. 18, 283-90 (2016).
-
(2016)
Neuro Oncol.
, vol.18
, pp. 283-290
-
-
De La Fuente, M.I.1
-
40
-
-
69949114447
-
Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: A study of 1,010 diffuse gliomas
-
Hartmann, C. et al. Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas. Acta Neuropathol. 118, 469-74 (2009).
-
(2009)
Acta Neuropathol.
, vol.118
, pp. 469-474
-
-
Hartmann, C.1
-
41
-
-
84873640990
-
The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization
-
Ward, P. S. et al. The Potential for Isocitrate Dehydrogenase Mutations to Produce 2-Hydroxyglutarate Depends on Allele Specificity and Subcellular Compartmentalization. The Journal of Biological Chemistry 288, 3804-3815 (2013).
-
(2013)
The Journal of Biological Chemistry
, vol.288
, pp. 3804-3815
-
-
Ward, P.S.1
-
42
-
-
78650855781
-
Implementation of 3T lactate-edited 3D 1H MR spectroscopic imaging with flyback echo-planar readout for gliomas patients
-
Park, I. et al. Implementation of 3T lactate-edited 3D 1H MR spectroscopic imaging with flyback echo-planar readout for gliomas patients. Ann Biomed Eng. 39, 193-204 (2011).
-
(2011)
Ann Biomed Eng.
, vol.39
, pp. 193-204
-
-
Park, I.1
-
43
-
-
70350695845
-
Quantification of magnetic resonance spectroscopy signals: The jMRUI software package
-
Stefan, D. et al. Quantification of magnetic resonance spectroscopy signals: the jMRUI software package. Meas Sci Technol. 20, 104035 (2009).
-
(2009)
Meas Sci Technol.
, vol.20
, pp. 104035
-
-
Stefan, D.1
-
44
-
-
84969659014
-
-
R Core Team R Foundation for Statistical Computing. ISBN 3-900051-07-0
-
R Core Team. R: A language and environment for statistical computing. R Foundation for Statistical Computing. ISBN 3-900051-07-0 (2013).
-
(2013)
A Language and Environment for Statistical Computing
-
-
-
45
-
-
84958985710
-
Noninvasive quantification of 2-hydroxyglutarate in human gliomas with IDH1 and IDH2 mutations
-
Emir, U. et al. Noninvasive Quantification of 2-Hydroxyglutarate in Human Gliomas with IDH1 and IDH2 mutations. Cancer Res. 76, 43-9 (2016).
-
(2016)
Cancer Res.
, vol.76
, pp. 43-49
-
-
Emir, U.1
|