New solutions to reduce discard of kidneys donated for transplantation

Journal of the American Society of Nephrology

Volumn 27, Issue 4, 2016, Pages 973-980

  Reese, Peter P ^a,b   Harhay, Meera N ^c   Abt, Peter L ^a   Levine, Matthew H ^a   Halpern, Scott D ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DISEASE TRANSMISSION; GRAFT SURVIVAL; HUMAN; KIDNEY DONOR; KIDNEY TRANSPLANTATION; NEPHROLOGIST; ORGAN DONOR; PATIENT REFERRAL; PRIORITY JOURNAL; DONOR; STANDARDS; STATISTICS AND NUMERICAL DATA; TRANSPLANTATION; WASTE DISPOSAL;

WASTE DISPOSAL;

HUMANS; KIDNEY TRANSPLANTATION; MEDICAL WASTE DISPOSAL; TISSUE AND ORGAN PROCUREMENT; TISSUE DONORS;

EID: 85016050258     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/asn.2015010023     Document Type: Article

References (40)

1. Based on OPTN data as of August 21, 2015. URL:http://optn.transplant.hrsa.gov/converge/latestData/rptData.asp
2. Wolfe RA, McCullough KP, Schaubel DE, Kalbfleisch JD, Murray S, Stegall MD, Leichtman AB: Calculating life years from transplant (LYFT): methods for kidney and kidney-pancreas candidates. Am J Transplant 8: 997–1011, 2008
3. Schold J, Srinivas TR, Sehgal AR, Meier-Kriesche HU: Half of kidney transplant candidates who are older than 60 years now placed on the waiting list will die before receiving a deceased-donor transplant. Clin J Am Soc Nephrol 4: 1239–1245, 2009
4. Grams ME, Massie AB, Schold JD, Chen BP, Segev DL: Trends in the inactive kidney transplant waitlist and implications for candidate survival. Am J Transplant 13: 1012–1018, 2013
5. Delmonico FL, McBride MA: Analysis of the wait list and deaths among candidates waiting for a kidney transplant. Transplantation 86: 1678–1683, 2008
6. Shafi S, Zimmerman B, Kalil R: Temporary inactive status on renal transplant waiting list: causes, risk factors, and outcomes. Transplant Proc 44: 1236–1240, 2012
7. Rao PS, Ojo A: The alphabet soup of kidney transplantation:SCD,DCD,ECD–fundamentals for the practicing nephrologist. Clin J Am Soc Nephrol 4: 1827–1831, 2009
8. Locke JE, Segev DL, Warren DS, Dominici F, Simpkins CE, Montgomery RA: Outcomes of kidneys from donors after cardiac death: implications for allocation and preservation. Am J Transplant 7: 1797–1807, 2007
9. Saidi RF, Elias N, Kawai T, Hertl M, Farrell ML, Goes N, Wong W, Hartono C, Fishman JA, Kotton CN, Tolkoff-Rubin N, Delmonico FL, Cosimi AB, Ko DS: Outcome of kidney transplantation using expanded criteria donors and donation after cardiac death kidneys: realities and costs. Am J Transplant 7: 2769–2774, 2007
10. Israni AK, Salkowski N, Gustafson S, Snyder JJ, Friedewald JJ, Formica RN, Wang X, Shteyn E, Cherikh W, Stewart D, Samana CJ, Chung A, Hart A, Kasiske BL: New national allocation policy for deceased donor kidneys in the United States and possible effect on patient outcomes. J Am Soc Nephrol 25: 1842–1848, 2014
11. Rao PS, Schaubel DE, Guidinger MK, Andreoni KA, Wolfe RA, Merion RM, Port FK, Sung RS: A comprehensive risk quantification score for deceased donor kidneys: the kidney donor risk index. Transplantation 88: 231–236, 2009
12. Organ Procurement and Transplantation Network: Guide to Calculating and Interpreting the KDPI. Available at: http://optn.transplant.hrsa.gov/ContentDocuments/Guide_to_Calculating_Interpreting_KDPI.pdf. Accessed December 31, 2014
13. Lee AP, Abramowicz D: Is the Kidney Donor Risk Index a step forward in the assessment of deceased donor kidney quality? Nephrol Dial Transplant 30: 1285–1290, 2015
14. Epstein M: Aging and the kidney. J Am Soc Nephrol 7: 1106–1122, 1996
15. Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, Van Lente F, Levey AS: Prevalence of chronic kidney disease in the United States. JAMA 298: 2038–2047, 2007
16. Fliser D, Franek E, Ritz E: Renal function in the elderly – is the dogma of an inexorable decline of renal function correct? Nephrol Dial Transplant 12: 1553–1555, 1997
17. Sung RS, Christensen LL, Leichtman AB, Greenstein SM, Distant DA, Wynn JJ, Stegall MD, Delmonico FL, Port FK: Determinants of discard of expanded criteria donor kidneys: impact of biopsy and machine perfusion. Am J Transplant 8: 783–792, 2008
18. Munivenkatappa RB, Schweitzer EJ, Papadimitriou JC, Drachenberg CB, Thom KA, Perencevich EN, Haririan A, Rasetto F, Cooper M, Campos L, Barth RN, Bartlett ST, Philosophe B: The Maryland aggregate pathology index: a deceased donor kidney biopsy scoring system for predicting graft failure. Am J Transplant 8: 2316–2324, 2008
19. Cockfield SM, Moore RB, Todd G, Solez K, Gourishankar S: The prognostic utility of deceased donor implantation biopsy in determining function and graft survival after kidney transplantation. Transplantation 89: 559–566, 2010
20. Bhangoo RS, Hall IE, Reese PP, Parikh CR: Deceased-donor kidney perfusate and urine biomarkers for kidney allograft outcomes: a systematic review. Nephrol Dial Transplant 27: 3305–3314, 2012
21. Seem DL, Lee I, Umscheid CA, Kuehnert MJ; United States Public Health Service: PHS guideline for reducing human immunodeficiency virus, hepatitis B virus, and hepatitis C virus transmission through organ transplantation. Public Health Rep 128: 247–343, 2013
22. Duan KI, Englesbe MJ, Volk ML: Centers for Disease Control ‘high-risk’ donors and kidney utilization. Am J Transplant 10: 416–420, 2010
23. Kucirka LM, Sarathy H, Govindan P, Wolf JH, Ellison TA, Hart LJ, Montgomery RA, Ros RL, Segev DL: Risk of window period hepatitis-C infection in high infectious risk donors: systematic review and meta-analysis. Am J Transplant 11: 1188–1200, 2011
24. Kucirka LM, Sarathy H, Govindan P, Wolf JH, Ellison TA, Hart LJ, Montgomery RA, Ros RL, Segev DL: Risk of window period HIV infection in high infectious risk donors: systematic review and meta-analysis. Am J Transplant 11: 1176–1187, 2011
25. Matas AJ, Smith JM, Skeans MA, Thompson B, Gustafson SK, Stewart DE, Cherikh WS, Wainright JL, Boyle G, Snyder JJ, Israni AK, Kasiske BL: OPTN/SRTR 2013 Annual Data Report: kidney. Am J Transplant 15[Suppl 2]: 1–34, 2015
26. Reese PP, Feldman HI, Asch DA, Halpern SD, Blumberg EA, Thomasson A, Shults J, Bloom RD: Transplantation of kidneys from donors at increased risk for blood-borne viral infection: recipient outcomes and patterns of organ use. Am J Transplant 9: 2338–2345, 2009
27. Reese PP, Tehrani T, Lim MA, Asch DA, Blumberg EA, Simon MK, Bloom RD, Halpern SD: Determinants of the decision to accept a kidney from a donor at increased risk for blood-borne viral infection. Clin J Am Soc Nephrol 5: 917–923, 2010
28. Massie AB, Luo X, Chow EK, Alejo JL, Desai NM, Segev DL: Survival benefit of primary deceased donor transplantation with high-KDPI kidneys. Am J Transplant 14: 2310–2316, 2014
29. Chow EK, Massie AB, Muzaale AD, Singer AL, Kucirka LM, Montgomery RA, Lehmann HP, Segev DL: Identifying appropriate recipients for CDC infectious risk donor kidneys. Am J Transplant 13: 1227–1234, 2013
30. Dew MA, Switzer GE, Goycoolea JM, Allen AS, DiMartini A, Kormos RL, Griffith BP: Does transplantation produce quality of life benefits? A quantitative analysis of the literature. Transplantation 64: 1261–1273, 1997
31. Schold JD, Buccini LD, Srinivas TR, Srinivas RT, Poggio ED, Flechner SM, Soria C, Segev DL, Fung J, Goldfarb DA: The association of center performance evaluations and kidney transplant volume in the United States. Am J Transplant 13: 67–75, 2013
32. Kasiske BL, McBride MA, Cornell DL, Gaston RS, Henry ML, Irwin FD, Israni AK, Metzler NW, Murphy KW, Reed AI, Roberts JP, Salkowski N, Snyder JJ, Sweet SC: Report of a consensus conference on transplant program quality and surveillance. Am J Transplant 12: 1988–1996, 2012
33. Garonzik-Wang JM, James NT, Weatherspoon KC, Deshpande NA, Berger JA, Hall EC, Montgomery RA, Segev DL: The aggressive phenotype: center-level patterns in the utilization of suboptimal kidneys. Am J Transplant 12: 400–408, 2012
34. Scientific Registry of Transplant Recipients: Guide to the Program-Specific Reports v 13.5, 2013. Available at: http://www.srtr.org/csr/archives/201106/all_csr_documentation.pdf. Accessed September 1, 2015
35. Remuzzi G, Grinyò J, Ruggenenti P, Beatini M, Cole EH, Milford EL, Brenner BM; Double Kidney Transplant Group (DKG): Early experience with dual kidney transplantation in adults using expanded donor criteria. J Am Soc Nephrol 10: 2591–2598, 1999
36. Tanriover B, Mohan S, Cohen DJ, Radhakrishnan J, Nickolas TL, Stone PW, Tsapepas DS, Crew RJ, Dube GK, Sandoval PR, Samstein B, Dogan E, Gaston RS, Tanriover JN, Ratner LE, Hardy MA: Kidneys at higher risk of discard: expanding the role of dual kidney transplantation. Am J Transplant 14: 404–415, 2014
37. Snyder J, Salkowski N, Zaun D, Schold J, Israni A, Kasiske B: The Effects of High-Risk Donors and Recipients on Scientific Registry of Transplant Recipients Program-Specific Outcomes [abstract]. Am J Transplant 15 (Suppl 3), 2015. Available at: http://www.atcmeetingabstracts.com/abstract/the-effects-of-high-risk-donors-and-recipients-on-scientific-registry-of-transplant-recipients-program-specific-outcomes/. Accessed May 12, 2015
38. Organ Procurement and Transplantation Network. Proposal to Implement Pre-Transplant Performance Review by the Membership and Professional Standards Committee. Available at: http://optn.transplant.hrsa.gov/media/1124/11_mpsc_pre_transplant_ performance.pdf. Accessed November 15, 2014
39. Organ Procurement and Transplantation Network: Kidney Allocation System (KAS) “Out-of-the-gate” monitoring report, April 23, 2015. Available at: http://optn.transplant.hrsa.gov/media/1168/kas_report_04-2015.pdf. Accessed May 12, 2015
40. Halpern SD, Shaked A, Hasz RD, Caplan AL: Informing candidates for solid-organ transplantation about donor risk factors. N Engl J Med 358: 2832–2837, 2008