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Volumn 25, Issue 24, 2016, Pages 5500-5512

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci

(57)  Zubair, Niha a   Graff, Mariaelisa b   Ambite, Jose Luis c   Bush, William S d   Kichaev, Gleb e   Lu, Yingchang f   Manichaikul, Ani g   Sheu, Wayne H H h   Absher, Devin i   Assimes, Themistocles L j   Bielinski, Suzette J k   Bottinger, Erwin P f   Buzkova, Petra l   Chuang, Lee Ming m   Chung, Ren Hua n   Cochran, Barbara o   Dumitrescu, Logan p   Gottesman, Omri f   Haessler, Jeffrey W a   Haiman, Christopher q   more..


Author keywords

[No Author keywords available]

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; ABC TRANSPORTER G8; ABCG8 PROTEIN, HUMAN; APOA5 PROTEIN, HUMAN; APOLIPOPROTEIN A5; LIPID; LIPOPROTEIN LIPASE; LPL PROTEIN, HUMAN;

EID: 85016010547     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddw358     Document Type: Article
Times cited : (24)

References (48)
  • 3
    • 84878502589 scopus 로고    scopus 로고
    • Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits
    • Zaitlen, N., Kraft, P., Patterson, N., Pasaniuc, B., Bhatia, G., Pollack, S. and Price, A.L. (2013) Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits. PLoS Genet., 9, e1003520.
    • (2013) PLoS Genet , vol.9
    • Zaitlen, N.1    Kraft, P.2    Patterson, N.3    Pasaniuc, B.4    Bhatia, G.5    Pollack, S.6    Price, A.L.7
  • 5
    • 37249029830 scopus 로고    scopus 로고
    • Genetic heterogeneity of autosomal dominant hypercholesterolemia
    • Varret, M., Abifadel, M., Rabes, J.P. and Boileau, C. (2008) Genetic heterogeneity of autosomal dominant hypercholesterolemia. Clin. Genet., 73, 1-13.
    • (2008) Clin. Genet , vol.73 , pp. 1-13
    • Varret, M.1    Abifadel, M.2    Rabes, J.P.3    Boileau, C.4
  • 6
    • 43449107670 scopus 로고    scopus 로고
    • Silent exonic mutations in the low-density lipoprotein receptor gene that cause familial hypercholesterolemia by affecting mRNA splicing
    • Defesche, J.C., Schuurman, E.J., Klaaijsen, L.N., Khoo, K.L., Wiegman, A. and Stalenhoef, A.F. (2008) Silent exonic mutations in the low-density lipoprotein receptor gene that cause familial hypercholesterolemia by affecting mRNA splicing. Clin. Genet., 73, 573-578.
    • (2008) Clin. Genet , vol.73 , pp. 573-578
    • Defesche, J.C.1    Schuurman, E.J.2    Klaaijsen, L.N.3    Khoo, K.L.4    Wiegman, A.5    Stalenhoef, A.F.6
  • 9
    • 84875996758 scopus 로고    scopus 로고
    • Trans-ethnic fine-mapping of lipid Loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained
    • Wu, Y., Waite, L.L., Jackson, A.U., Sheu, W.H., Buyske, S., Absher, D., Arnett, D.K., Boerwinkle, E., Bonnycastle, L.L., Carty, C.L., et al. (2013) Trans-ethnic fine-mapping of lipid Loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. PLoS Genet., 9, e1003379.
    • (2013) PLoS Genet , vol.9
    • Wu, Y.1    Waite, L.L.2    Jackson, A.U.3    Sheu, W.H.4    Buyske, S.5    Absher, D.6    Arnett, D.K.7    Boerwinkle, E.8    Bonnycastle, L.L.9    Carty, C.L.10
  • 11
    • 77958604488 scopus 로고    scopus 로고
    • Identifying candidate causal variants via trans-population fine-mapping
    • Teo, Y.Y., Ong, R.T., Sim, X., Tai, E.S. and Chia, K.S. (2010) Identifying candidate causal variants via trans-population fine-mapping. Genet. Epidemiol., 34, 653-664.
    • (2010) Genet. Epidemiol , vol.34 , pp. 653-664
    • Teo, Y.Y.1    Ong, R.T.2    Sim, X.3    Tai, E.S.4    Chia, K.S.5
  • 13
  • 16
    • 67649834099 scopus 로고    scopus 로고
    • Inhibition of PCSK9: a powerful weapon for achieving ideal LDL cholesterol levels
    • Steinberg, D. and Witztum, J.L. (2009) Inhibition of PCSK9: a powerful weapon for achieving ideal LDL cholesterol levels. Proc. Natl Acad. Sci. U S A, 106, 9546-9547.
    • (2009) Proc. Natl Acad. Sci. U S A , vol.106 , pp. 9546-9547
    • Steinberg, D.1    Witztum, J.L.2
  • 25
  • 29
    • 84902532316 scopus 로고    scopus 로고
    • Accuracy of administratively-assigned ancestry for diverse populations in an electronic medical record-linked biobank
    • Hall, J.B., Dumitrescu, L., Dilks, H.H., Crawford, D.C. and Bush, W.S. (2014) Accuracy of administratively-assigned ancestry for diverse populations in an electronic medical record-linked biobank. PLoS One, 9, e99161.
    • (2014) PLoS One , vol.9
    • Hall, J.B.1    Dumitrescu, L.2    Dilks, H.H.3    Crawford, D.C.4    Bush, W.S.5
  • 30
    • 84859120701 scopus 로고    scopus 로고
    • Genotype imputation of Metabochip SNPs using a study-specific reference panel of °4, 000 haplotypes in African Americans from the Women's Health Initiative
    • Liu, E.Y., Buyske, S., Aragaki, A.K., Peters, U., Boerwinkle, E., Carlson, C., Carty, C., Crawford, D.C., Haessler, J., Hindorff, L.A., et al. (2012) Genotype imputation of Metabochip SNPs using a study-specific reference panel of °4, 000 haplotypes in African Americans from the Women's Health Initiative. Genet. Epidemiol., 36, 107-117.
    • (2012) Genet. Epidemiol , vol.36 , pp. 107-117
    • Liu, E.Y.1    Buyske, S.2    Aragaki, A.K.3    Peters, U.4    Boerwinkle, E.5    Carlson, C.6    Carty, C.7    Crawford, D.C.8    Haessler, J.9    Hindorff, L.A.10
  • 32
    • 35648987626 scopus 로고    scopus 로고
    • An investigation of the effects of lipid-lowering medications: genomewide linkage analysis of lipids in the HyperGEN study
    • Wu, J., Province, M., Coon, H., Hunt, S., Eckfeldt, J., Arnett, D., Heiss, G., Lewis, C., Ellison, R., Rao, D., et al. (2007) An investigation of the effects of lipid-lowering medications: genomewide linkage analysis of lipids in the HyperGEN study. BMC Genet., 8, 60.
    • (2007) BMC Genet , vol.8 , pp. 60
    • Wu, J.1    Province, M.2    Coon, H.3    Hunt, S.4    Eckfeldt, J.5    Arnett, D.6    Heiss, G.7    Lewis, C.8    Ellison, R.9    Rao, D.10
  • 33
    • 0035897696 scopus 로고    scopus 로고
    • Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection, E. and Adults, T.o.H.B.C.i. (2001) Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA, 285, 2486-2497.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 34
    • 34548285811 scopus 로고    scopus 로고
    • Ezetimibe: an update on the mechanism of action, pharmacokinetics and recent clinical trials
    • Sweeney, M.E. and Johnson, R.R. (2007) Ezetimibe: an update on the mechanism of action, pharmacokinetics and recent clinical trials. Expert Opin. Drug Metab. Toxicol., 3, 441-450.
    • (2007) Expert Opin. Drug Metab. Toxicol , vol.3 , pp. 441-450
    • Sweeney, M.E.1    Johnson, R.R.2
  • 36
    • 34547628858 scopus 로고    scopus 로고
    • Family-based association tests for genomewide association scans
    • Chen, W.M. and Abecasis, G.R. (2007) Family-based association tests for genomewide association scans. Am. J. Hum.Genet., 81, 913-926.
    • (2007) Am. J. Hum.Genet , vol.81 , pp. 913-926
    • Chen, W.M.1    Abecasis, G.R.2
  • 37
    • 77955894071 scopus 로고    scopus 로고
    • METAL: fast and efficient meta-analysis of genomewide association scans
    • Willer, C.J., Li, Y. and Abecasis, G.R. (2010) METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics, 26, 2190-2191.
    • (2010) Bioinformatics , vol.26 , pp. 2190-2191
    • Willer, C.J.1    Li, Y.2    Abecasis, G.R.3
  • 38
    • 79955860273 scopus 로고    scopus 로고
    • Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies
    • Han, B. and Eskin, E. (2011) Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. Am. J. Hum. Genet., 88, 586-598.
    • (2011) Am. J. Hum. Genet , vol.88 , pp. 586-598
    • Han, B.1    Eskin, E.2
  • 39
    • 84938982145 scopus 로고    scopus 로고
    • Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies
    • Kichaev, G. and Pasaniuc, B. (2015) Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies. Am. J. Hum. Genet., 97, 260-271.
    • (2015) Am. J. Hum. Genet , vol.97 , pp. 260-271
    • Kichaev, G.1    Pasaniuc, B.2
  • 45


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