Neutrophils orchestrate post-myocardial infarction healing by polarizing macrophages towards a reparative phenotype

European Heart Journal

Volumn 38, Issue 3, 2017, Pages 187-197

  Horckmans, Michael ^a   Ring, Larisa ^a   Duchene, Johan ^a   Santovito, Donato ^a,b   Schloss, Maximilian J ^a   Drechsler, Maik ^a,c,d   Weber, Christian ^a,c   Soehnlein, Oliver ^a,c,d   Steffens, Sabine ^a,c  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF CHIETI   (Italy)

^c DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Adverse remodeling; Efferocytosis; Lipocalin; Macrophages; Myocardial infarction healing; Neutrophils

Indexed keywords

ANTIINFLAMMATORY AGENT; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PROTEIN KINASE; MERTK PROTEIN, MOUSE; PROTEIN KINASE MER;

ACUTE HEART INFARCTION; ARTICLE; CELL PROLIFERATION; ECHOCARDIOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROSIS; FLOW CYTOMETRY; HEALING; HEART FAILURE; HEART FUNCTION; IMMUNOPRECIPITATION; MACROPHAGE; MORTALITY; MOUSE; NONHUMAN; POLARIZATION; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; TISSUE INJURY; WESTERN BLOTTING; ANIMAL; APOPTOSIS; C57BL MOUSE; HEART INFARCTION; HEART MUSCLE FIBROSIS; HEART VENTRICLE REMODELING; LIGATION; METABOLISM; MONOCYTE; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NEUTROPENIA; NEUTROPHIL; PATHOPHYSIOLOGY; PHENOTYPE; PHYSIOLOGY; WOUND HEALING;

ANIMALS; APOPTOSIS; C-MER TYROSINE KINASE; CELL PROLIFERATION; ENDOMYOCARDIAL FIBROSIS; FEMALE; HEART FAILURE; LIGATION; LIPOCALIN-2; MACROPHAGES; MICE, INBRED C57BL; MONOCYTES; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; NEUTROPENIA; NEUTROPHILS; PHENOTYPE; VENTRICULAR REMODELING; WOUND HEALING;

EID: 85015963502     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehw002     Document Type: Article

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