메뉴 건너뛰기




Volumn 6, Issue 1, 2016, Pages

IL-2 in the tumor microenvironment is necessary for Wiskott-Aldrich syndrome protein deficient NK cells to respond to tumors in vivo article

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CD226 ANTIGEN; CD56 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; NCAM1 PROTEIN, HUMAN; T LYMPHOCYTE ANTIGEN; WISKOTT ALDRICH SYNDROME PROTEIN;

EID: 85015669882     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep30636     Document Type: Article
Times cited : (24)

References (53)
  • 1
    • 33745567831 scopus 로고    scopus 로고
    • Self-tolerance of natural killer cells
    • Raulet, D. H. & Vance, R. E. Self-tolerance of natural killer cells. Nat Rev Immunol 6, 520-531 (2006).
    • (2006) Nat Rev Immunol , vol.6 , pp. 520-531
    • Raulet, D.H.1    Vance, R.E.2
  • 2
    • 23044486686 scopus 로고    scopus 로고
    • Missing self, NK cells, and the white album
    • Lanier, L. L. Missing self, NK cells, and The White Album. J Immunol 174, 6565 (2005).
    • (2005) J Immunol , vol.174 , pp. 6565
    • Lanier, L.L.1
  • 3
    • 84858784892 scopus 로고    scopus 로고
    • Targeting natural killer cells and natural killer T cells in cancer
    • Vivier, E., Ugolini, S., Blaise, D., Chabannon, C. & Brossay, L. Targeting natural killer cells and natural killer T cells in cancer. Nat Rev Immunol 12, 239-252 (2012).
    • (2012) Nat Rev Immunol , vol.12 , pp. 239-252
    • Vivier, E.1    Ugolini, S.2    Blaise, D.3    Chabannon, C.4    Brossay, L.5
  • 4
    • 84872920040 scopus 로고    scopus 로고
    • Variable NK cell receptors and their MHC class i ligands in immunity, reproduction and human evolution
    • Parham, P. & Moffett, A. Variable NK cell receptors and their MHC class I ligands in immunity, reproduction and human evolution. Nat Rev Immunol 13, 133-144 (2013).
    • (2013) Nat Rev Immunol , vol.13 , pp. 133-144
    • Parham, P.1    Moffett, A.2
  • 5
    • 80053133221 scopus 로고    scopus 로고
    • NK cell development, homeostasis and function: Parallels with CD8(+) T cells
    • Sun, J. C. & Lanier, L. L. NK cell development, homeostasis and function: parallels with CD8(+) T cells. Nat Rev Immunol 11, 645-657 (2011).
    • (2011) Nat Rev Immunol , vol.11 , pp. 645-657
    • Sun, J.C.1    Lanier, L.L.2
  • 6
    • 0022616253 scopus 로고
    • Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy
    • Karre, K., Ljunggren, H. G., Piontek, G. & Kiessling, R. Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. Nature 319, 675-678 (1986).
    • (1986) Nature , vol.319 , pp. 675-678
    • Karre, K.1    Ljunggren, H.G.2    Piontek, G.3    Kiessling, R.4
  • 7
    • 63849099445 scopus 로고    scopus 로고
    • The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells
    • Brodin, P., Lakshmikanth, T., Johansson, S., Karre, K. & Hoglund, P. The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells. Blood 113, 2434-2441 (2009).
    • (2009) Blood , vol.113 , pp. 2434-2441
    • Brodin, P.1    Lakshmikanth, T.2    Johansson, S.3    Karre, K.4    Hoglund, P.5
  • 8
    • 18844365992 scopus 로고    scopus 로고
    • A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self- MHC molecules
    • Fernandez, N. C. et al. A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self- MHC molecules. Blood 105, 4416-4423 (2005).
    • (2005) Blood , vol.105 , pp. 4416-4423
    • Fernandez, N.C.1
  • 9
    • 23644458333 scopus 로고    scopus 로고
    • Licensing of natural killer cells by host major histocompatibility complex class i molecules
    • Kim, S. et al. Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature 436, 709-713 (2005).
    • (2005) Nature , vol.436 , pp. 709-713
    • Kim, S.1
  • 10
    • 84937837169 scopus 로고    scopus 로고
    • Molecular and cellular insights into T cell exhaustion
    • Wherry, E. J. & Kurachi, M. Molecular and cellular insights into T cell exhaustion. Nat Rev Immunol 15, 486-499 (2015).
    • (2015) Nat Rev Immunol , vol.15 , pp. 486-499
    • Wherry, E.J.1    Kurachi, M.2
  • 11
    • 36048963838 scopus 로고    scopus 로고
    • LAG-3 regulates CD8+ T cell accumulation and effector function in murine self- and tumor-tolerance systems
    • Grosso, J. F. et al. LAG-3 regulates CD8+ T cell accumulation and effector function in murine self- and tumor-tolerance systems. J Clin Invest 117, 3383-3392 (2007).
    • (2007) J Clin Invest , vol.117 , pp. 3383-3392
    • Grosso, J.F.1
  • 12
    • 68249151160 scopus 로고    scopus 로고
    • Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition
    • Li, Y. et al. Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition. Immunity 31, 35-46 (2009).
    • (2009) Immunity , vol.31 , pp. 35-46
    • Li, Y.1
  • 13
    • 77951764036 scopus 로고    scopus 로고
    • Functional plasticity and robustness are essential characteristics of biological systems: Lessons learned from KLRG1- deficient mice
    • Jonjic, S. Functional plasticity and robustness are essential characteristics of biological systems: lessons learned from KLRG1- deficient mice. Eur J Immunol 40, 1241-1243 (2010).
    • (2010) Eur J Immunol , vol.40 , pp. 1241-1243
    • Jonjic, S.1
  • 14
    • 84896713527 scopus 로고    scopus 로고
    • KLRG1+ NK cells protect T-bet-deficient mice from pulmonary metastatic colorectal carcinoma
    • Malaise, M. et al. KLRG1+ NK cells protect T-bet-deficient mice from pulmonary metastatic colorectal carcinoma. J Immunol 192, 1954-1961 (2014).
    • (2014) J Immunol , vol.192 , pp. 1954-1961
    • Malaise, M.1
  • 15
    • 84885364301 scopus 로고    scopus 로고
    • The central role of the cytoskeleton in mechanisms and functions of the NK cell immune synapse
    • Lagrue, K. et al. The central role of the cytoskeleton in mechanisms and functions of the NK cell immune synapse. Immunol Rev 256, 203-221 (2013).
    • (2013) Immunol Rev , vol.256 , pp. 203-221
    • Lagrue, K.1
  • 16
    • 14044276352 scopus 로고    scopus 로고
    • The Wiskott-Aldrich syndrome protein regulates nuclear translocation of NFAT2 and NF-kappa B (RelA) independently of its role in filamentous actin polymerization and actin cytoskeletal rearrangement
    • Huang, W., Ochs, H. D., Dupont, B. & Vyas, Y. M. The Wiskott-Aldrich syndrome protein regulates nuclear translocation of NFAT2 and NF-kappa B (RelA) independently of its role in filamentous actin polymerization and actin cytoskeletal rearrangement. J Immunol 174, 2602-2611 (2005).
    • (2005) J Immunol , vol.174 , pp. 2602-2611
    • Huang, W.1    Ochs, H.D.2    Dupont, B.3    Vyas, Y.M.4
  • 17
    • 79953331939 scopus 로고    scopus 로고
    • IL-2 induces a WAVE2-dependent pathway for actin reorganization that enables WASp-independent human NK cell function
    • Orange, J. S. et al. IL-2 induces a WAVE2-dependent pathway for actin reorganization that enables WASp-independent human NK cell function. J Clin Invest 121, 1535-1548, (2011).
    • (2011) J Clin Invest , vol.121 , pp. 1535-1548
    • Orange, J.S.1
  • 20
    • 0028116532 scopus 로고
    • A multiinstitutional survey of the Wiskott-Aldrich syndrome
    • Sullivan, K. E., Mullen, C. A., Blaese, R. M. & Winkelstein, J. A. A multiinstitutional survey of the Wiskott-Aldrich syndrome. J Pediatr 125, 876-885 (1994).
    • (1994) J Pediatr , vol.125 , pp. 876-885
    • Sullivan, K.E.1    Mullen, C.A.2    Blaese, R.M.3    Winkelstein, J.A.4
  • 21
    • 0026697955 scopus 로고
    • Primary immunodeficiencies: Genetic risk factors for lymphoma
    • Filipovich, A. H., Mathur, A., Kamat, D. & Shapiro, R. S. Primary immunodeficiencies: genetic risk factors for lymphoma. Cancer Res 52, 5465s-5467s (1992).
    • (1992) Cancer Res , vol.52 , pp. 5465s-5467s
    • Filipovich, A.H.1    Mathur, A.2    Kamat, D.3    Shapiro, R.S.4
  • 22
    • 42549137374 scopus 로고    scopus 로고
    • Development of cancer in patients with primary immunodeficiencies
    • Salavoura, K., Kolialexi, A., Tsangaris, G. & Mavrou, A. Development of cancer in patients with primary immunodeficiencies. Anticancer Res 28, 1263-1269 (2008).
    • (2008) Anticancer Res , vol.28 , pp. 1263-1269
    • Salavoura, K.1    Kolialexi, A.2    Tsangaris, G.3    Mavrou, A.4
  • 23
    • 84898006391 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein deficiency in natural killer and dendritic cells affects antitumor immunity
    • Catucci, M. et al. Wiskott-Aldrich syndrome protein deficiency in natural killer and dendritic cells affects antitumor immunity. Eur J Immunol 44, 1039-1045 (2014).
    • (2014) Eur J Immunol , vol.44 , pp. 1039-1045
    • Catucci, M.1
  • 24
    • 84881610907 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein regulates leukocyte-dependent breast cancer metastasis
    • Ishihara, D. et al. Wiskott-Aldrich syndrome protein regulates leukocyte-dependent breast cancer metastasis. Cell reports 4, 429-436 (2013).
    • (2013) Cell Reports , vol.4 , pp. 429-436
    • Ishihara, D.1
  • 25
    • 3142585003 scopus 로고    scopus 로고
    • Impaired natural and CD16-mediated NK cell cytotoxicity in patients with WAS and XLT: Ability of IL-2 to correct NK cell functional defect
    • Gismondi, A. et al. Impaired natural and CD16-mediated NK cell cytotoxicity in patients with WAS and XLT: ability of IL-2 to correct NK cell functional defect. Blood 104, 436-443 (2004).
    • (2004) Blood , vol.104 , pp. 436-443
    • Gismondi, A.1
  • 26
    • 81555208975 scopus 로고    scopus 로고
    • Identification of the earliest natural killer cell-committed progenitor in murine bone marrow
    • Fathman, J. W. et al. Identification of the earliest natural killer cell-committed progenitor in murine bone marrow. Blood 118, 5439-5447 (2011).
    • (2011) Blood , vol.118 , pp. 5439-5447
    • Fathman, J.W.1
  • 27
    • 17144365824 scopus 로고    scopus 로고
    • Natural killer cell education in mice with single or multiple major histocompatibility complex class i molecules
    • Johansson, S. et al. Natural killer cell education in mice with single or multiple major histocompatibility complex class I molecules. J Exp Med 201, 1145-1155 (2005).
    • (2005) J Exp Med , vol.201 , pp. 1145-1155
    • Johansson, S.1
  • 28
    • 9144273834 scopus 로고    scopus 로고
    • CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation
    • Shibuya, K. et al. CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation. J Exp Med 198, 1829-1839 (2003).
    • (2003) J Exp Med , vol.198 , pp. 1829-1839
    • Shibuya, K.1
  • 29
    • 84862777436 scopus 로고    scopus 로고
    • The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation
    • Gordon, S. M. et al. The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation. Immunity 36, 55-67 (2012).
    • (2012) Immunity , vol.36 , pp. 55-67
    • Gordon, S.M.1
  • 30
    • 84937596884 scopus 로고    scopus 로고
    • Quiescence of memory CD8(+) T cells is mediated by regulatory T cells through inhibitory receptor CTLA-4
    • Kalia, V., Penny, L. A., Yuzefpolskiy, Y., Baumann, F. M. & Sarkar, S. Quiescence of Memory CD8(+) T Cells Is Mediated by Regulatory T Cells through Inhibitory Receptor CTLA-4. Immunity 42, 1116-1129 (2015).
    • (2015) Immunity , vol.42 , pp. 1116-1129
    • Kalia, V.1    Penny, L.A.2    Yuzefpolskiy, Y.3    Baumann, F.M.4    Sarkar, S.5
  • 31
    • 0037143734 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cellactivating immunologic synapses
    • Orange, J. S. et al. Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cellactivating immunologic synapses. Proc Natl Acad Sci USA 99, 11351-11356 (2002).
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 11351-11356
    • Orange, J.S.1
  • 32
    • 10844246498 scopus 로고    scopus 로고
    • Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: Critical role of DNAX accessory molecule-1-poliovirus receptor interaction
    • Castriconi, R. et al. Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: critical role of DNAX accessory molecule-1-poliovirus receptor interaction. Cancer Res 64, 9180-9184 (2004).
    • (2004) Cancer Res , vol.64 , pp. 9180-9184
    • Castriconi, R.1
  • 34
    • 57149128460 scopus 로고    scopus 로고
    • Primary immune deficiencies with aberrant IgE production
    • Ozcan, E., Notarangelo, L. D. & Geha, R. S. Primary immune deficiencies with aberrant IgE production. J Allergy Clin Immunol 122, 1054-1062 (2008).
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 1054-1062
    • Ozcan, E.1    Notarangelo, L.D.2    Geha, R.S.3
  • 35
    • 79953840956 scopus 로고    scopus 로고
    • Confinement of activating receptors at the plasma membrane controls natural killer cell tolerance
    • Guia, S. et al. Confinement of activating receptors at the plasma membrane controls natural killer cell tolerance. Sci Signal 4, ra21 (2011).
    • (2011) Sci Signal , vol.4 , pp. ra21
    • Guia, S.1
  • 36
    • 84880909774 scopus 로고    scopus 로고
    • Superresolution microscopy reveals nanometer-scale reorganization of inhibitory natural killer cell receptors upon activation of NKG2D
    • Pageon, S. V. et al. Superresolution microscopy reveals nanometer-scale reorganization of inhibitory natural killer cell receptors upon activation of NKG2D. Sci Signal 6, ra62 (2013).
    • (2013) Sci Signal , vol.6 , pp. ra62
    • Pageon, S.V.1
  • 37
    • 34848899850 scopus 로고    scopus 로고
    • Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development
    • Cotta-de-Almeida, V. et al. Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development. Proc Natl Acad Sci USA 104, 15424-15429 (2007).
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15424-15429
    • Cotta-De-Almeida, V.1
  • 38
    • 84860333144 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein (WASP) and N-WASP are critical for peripheral B-cell development and function
    • Westerberg, L. S. et al. Wiskott-Aldrich syndrome protein (WASP) and N-WASP are critical for peripheral B-cell development and function. Blood 119, 3966-3974 (2012).
    • (2012) Blood , vol.119 , pp. 3966-3974
    • Westerberg, L.S.1
  • 39
    • 78049252250 scopus 로고    scopus 로고
    • CD56 negative NK cells: Origin, function, and role in chronic viral disease
    • Bjorkstrom, N. K., Ljunggren, H. G. & Sandberg, J. K. CD56 negative NK cells: origin, function, and role in chronic viral disease. Trends in immunology 31, 401-406 (2010).
    • (2010) Trends in Immunology , vol.31 , pp. 401-406
    • Bjorkstrom, N.K.1    Ljunggren, H.G.2    Sandberg, J.K.3
  • 40
    • 84894261203 scopus 로고    scopus 로고
    • Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection
    • Nabekura, T. et al. Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection. Immunity 40, 225-234 (2014).
    • (2014) Immunity , vol.40 , pp. 225-234
    • Nabekura, T.1
  • 41
    • 84927691776 scopus 로고    scopus 로고
    • DNAM-1 expression marks an alternative program of NK cell maturation
    • Martinet, L. et al. DNAM-1 expression marks an alternative program of NK cell maturation. Cell reports 11, 85-97 (2015).
    • (2015) Cell Reports , vol.11 , pp. 85-97
    • Martinet, L.1
  • 42
    • 68849120512 scopus 로고    scopus 로고
    • Heterogeneous expression of the adhesion receptor CD226 on murine NK and T cells and its function in NK-mediated killing of immature dendritic cells
    • Seth, S. et al. Heterogeneous expression of the adhesion receptor CD226 on murine NK and T cells and its function in NK-mediated killing of immature dendritic cells. J Leukoc Biol 86, 91-101 (2009).
    • (2009) J Leukoc Biol , vol.86 , pp. 91-101
    • Seth, S.1
  • 43
    • 0042922822 scopus 로고    scopus 로고
    • Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule
    • Bottino, C. et al. Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule. J Exp Med 198, 557-567 (2003).
    • (2003) J Exp Med , vol.198 , pp. 557-567
    • Bottino, C.1
  • 44
    • 34548027000 scopus 로고    scopus 로고
    • Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor
    • Joshi, N. S. et al. Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity 27, 281-295 (2007).
    • (2007) Immunity , vol.27 , pp. 281-295
    • Joshi, N.S.1
  • 45
    • 84862776988 scopus 로고    scopus 로고
    • Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'
    • Levin, A. M. et al. Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'. Nature 484, 529-533 (2012).
    • (2012) Nature , vol.484 , pp. 529-533
    • Levin, A.M.1
  • 46
    • 84908636831 scopus 로고    scopus 로고
    • Cytokine therapy reverses NK cell anergy in MHC-deficient tumors
    • Ardolino, M. et al. Cytokine therapy reverses NK cell anergy in MHC-deficient tumors. J Clin Invest 124, 4781-4794 (2014).
    • (2014) J Clin Invest , vol.124 , pp. 4781-4794
    • Ardolino, M.1
  • 47
    • 77957747686 scopus 로고    scopus 로고
    • Mature natural killer cells reset their responsiveness when exposed to an altered MHC environment
    • Joncker, N. T., Shifrin, N., Delebecque, F. & Raulet, D. H. Mature natural killer cells reset their responsiveness when exposed to an altered MHC environment. J Exp Med 207, 2065-2072 (2010).
    • (2010) J Exp Med , vol.207 , pp. 2065-2072
    • Joncker, N.T.1    Shifrin, N.2    Delebecque, F.3    Raulet, D.H.4
  • 48
    • 84962040501 scopus 로고    scopus 로고
    • Retuning of mouse NK cells after interference with MHC class i sensing adjusts self-tolerance but preserves anticancer response
    • Wagner, A. K. et al. Retuning of Mouse NK Cells after Interference with MHC Class I Sensing Adjusts Self-Tolerance but Preserves Anticancer Response. Cancer immunology research 4, 113-123 (2016).
    • (2016) Cancer Immunology Research , vol.4 , pp. 113-123
    • Wagner, A.K.1
  • 49
    • 75949102905 scopus 로고    scopus 로고
    • Use of cytokine therapy in primary immunodeficiency
    • Roy-Ghanta, S. & Orange, J. S. Use of cytokine therapy in primary immunodeficiency. Clin Rev Allergy Immunol 38, 39-53 (2010).
    • (2010) Clin Rev Allergy Immunol , vol.38 , pp. 39-53
    • Roy-Ghanta, S.1    Orange, J.S.2
  • 51
    • 67650433317 scopus 로고    scopus 로고
    • Natural killer cell-based immunotherapy in cancer: Current insights and future prospects
    • Sutlu, T. & Alici, E. Natural killer cell-based immunotherapy in cancer: current insights and future prospects. Journal of internal medicine 266, 154-181 (2009).
    • (2009) Journal of Internal Medicine , vol.266 , pp. 154-181
    • Sutlu, T.1    Alici, E.2
  • 52
    • 23244465352 scopus 로고    scopus 로고
    • Genotype-proteotype linkage in the Wiskott-Aldrich syndrome
    • Lutskiy, M. I., Rosen, F. S. & Remold-O'Donnell, E. Genotype-proteotype linkage in the Wiskott-Aldrich syndrome. J Immunol 175, 1329-1336 (2005).
    • (2005) J Immunol , vol.175 , pp. 1329-1336
    • Lutskiy, M.I.1    Rosen, F.S.2    Remold-O'Donnell, E.3
  • 53
    • 84896698546 scopus 로고    scopus 로고
    • A genetic defect in mice that impairs missing self recognition despite evidence for normal maturation and MHC class I-dependent education of NK cells
    • Wickstrom, S. L., Oberg, L., Karre, K. & Johansson, M. H. A genetic defect in mice that impairs missing self recognition despite evidence for normal maturation and MHC class I-dependent education of NK cells. J Immunol 192, 1577-1586 (2014).
    • (2014) J Immunol , vol.192 , pp. 1577-1586
    • Wickstrom, S.L.1    Oberg, L.2    Karre, K.3    Johansson, M.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.