TGF-β inhibitors stimulate red blood cell production by enhancing self-renewal of BFU-E erythroid progenitors

Blood

Volumn 128, Issue 23, 2016, Pages 2637-2641

  Gao, Xiaofei ^a   Lee, Hsiang Ying ^a   Da Rocha, Edroaldo Lummertz ^b   Zhang, Cheng ^b   Lu, Yi Fen ^c   Li, Dandan ^d   Feng, Yuxiong ^a   Ezike, Jideofor ^a   Elmes, Russell R ^a   Inmaculada Barrasa, M ^a   Cahan, Patrick ^e   Li, Hu ^b   Daley, George Q ^c   Lodish, Harvey F ^a,f  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^e Johns Hopkins University   (United States)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GALUNISERTIB; GLUCOCORTICOID RECEPTOR; RIBOSOME PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; DIFFERENTIATION ANTIGEN; ERYTHROPOIETIN; PROTEOGLYCAN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3;

ANIMAL CELL; ARTICLE; BURST FORMING UNIT E; CELL DIFFERENTIATION; CELL SELF-RENEWAL; CONTROLLED STUDY; ERYTHROBLAST; ERYTHROCYTE; ERYTHROID PRECURSOR CELL; FETUS LIVER; GENE EXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; RNA SEQUENCE; ANEMIA; ANIMAL; CYTOLOGY; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANEMIA; ANIMALS; ANTIGENS, DIFFERENTIATION; ERYTHROCYTES; ERYTHROID PRECURSOR CELLS; ERYTHROPOIETIN; HUMANS; MICE; PROTEOGLYCANS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 85015630429     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2016-05-718320     Document Type: Article

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