Pre-steady-state kinetics reveal the substrate specificity and mechanism of halide oxidation of truncated human peroxidasin 1

Journal of Biological Chemistry

Volumn 292, Issue 11, 2017, Pages 4583-4592

  Paumann Page, Martina ^a   Katz, Romy Sophie ^a   Bellei, Marzia ^b   Schwartz, Irene ^a   Edenhofer, Eva ^a   Sevcnikar, Benjamin ^a   Soudi, Monika ^a   Hofbauer, Stefan ^a   Battistuzzi, Gianantonio ^b   Furtmüller, Paul G ^a   Obinger, Christian ^a  

^a UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; ENZYMES; IODINE; OXIDATION; PORPHYRINS; RATE CONSTANTS;

BIMOLECULAR RATE CONSTANTS; COVALENT CROSS-LINKS; EXTRACELLULAR MATRICES; IMMUNOGLOBULIN-LIKE DOMAINS; INTERMEDIATE COMPOUND; STANDARD REDUCTION POTENTIALS; STOPPED-FLOW STUDIES; SUBSTRATE SPECIFICITY;

REACTION INTERMEDIATES;

BROMIDE; CHLORIDE; COLLAGEN TYPE 4; HEME; HYDROGEN PEROXIDE; IODIDE; IRON; PEROXIDASE; PEROXIDASIN 1; THIOCYANATE; UNCLASSIFIED DRUG; FERRIC ION; PEROXIDASIN; SCLEROPROTEIN; THIOCYANIC ACID DERIVATIVE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HALIDE OXIDATION; HALOGENATION; HUMAN; HUMAN CELL; OXIDATION; OXIDATION REDUCTION REACTION; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN MODIFICATION; CHEMISTRY; ENZYME ACTIVE SITE; KINETICS; METABOLISM;

BROMIDES; CATALYTIC DOMAIN; CHLORIDES; COLLAGEN TYPE IV; EXTRACELLULAR MATRIX PROTEINS; FERRIC COMPOUNDS; HALOGENATION; HUMANS; HYDROGEN PEROXIDE; IODIDES; KINETICS; OXIDATION-REDUCTION; PEROXIDASE; PROTEIN DOMAINS; SUBSTRATE SPECIFICITY; THIOCYANATES;

EID: 85015345606     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M117.775213     Document Type: Article

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