Structural basis for inhibition of erythrocyte invasion by antibodies to plasmodium falciparum protein CyRPA

eLife

Volumn 6, Issue , 2017, Pages

  Chen, Lin ^a,b   Xu, Yibin ^a,b   Wong, Wilson ^a,b   Thompson, Jennifer K ^a   Healer, Julie ^a   Goddard Borger, Ethan D ^a,b   Lawrence, Michael C ^a,b   Cowman, Alan F ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CYRPA PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; PEPTIDES AND PROTEINS; PFRH5; UNCLASSIFIED DRUG; CARRIER PROTEIN; CYRPA PROTEIN, PLASMODIUM FALCIPARUM; MALARIA VACCINE; PARASITE ANTIGEN; PROTEIN BINDING; PROTOZOAL PROTEIN; PROTOZOON ANTIBODY; RH5 PROTEIN, PLASMODIUM FALCIPARUM; RIPR PROTEIN, PLASMODIUM FALCIPARUM;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIGEN BINDING; ARTICLE; CELL INVASION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ERYTHROCYTE; GROWTH INHIBITION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PURIFICATION; SIZE EXCLUSION CHROMATOGRAPHY; CHEMISTRY; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; CARRIER PROTEINS; CRYSTALLOGRAPHY, X-RAY; MALARIA VACCINES; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTOZOAN PROTEINS;

EID: 85015334698     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.21347     Document Type: Article

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