Clostridium difficile-derived membrane vesicles induce the expression of pro-inflammatory cytokine genes and cytotoxicity in colonic epithelial cells in vitro

Microbial Pathogenesis

Volumn 107, Issue , 2017, Pages 6-11

  Nicholas, Asiimwe ^a   Jeon, Hyejin ^a   Selasi, Gati Noble ^a   Na, Seok Hyeon ^a   Kwon, Hyo Il ^a   Kim, Yoo Jeong ^a   Choi, Chi Won ^b   Kim, Seung Il ^b   Lee, Je Chul ^a  

^a Kyungpook National University School of Medicine   (South Korea)

^b Korea Basic Science Institute (KBSI)   (South Korea)

Author keywords

C. difficile; Cytotoxicity; Membrane vesicle; Pro inflammatory cytokines

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; BACTERIAL PROTEIN; BACTERIAL TOXIN; CCL2 PROTEIN, HUMAN; CYTOKINE; ENTEROTOXIN; TCDA PROTEIN, CLOSTRIDIUM DIFFICILE; TOXB PROTEIN, CLOSTRIDIUM DIFFICILE;

ARTICLE; BACTERIAL MEMBRANE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CELL MEMBRANE; CLOSTRIDIUM DIFFICILE INFECTION; COLON CELL; CONTROLLED STUDY; CYTOTOXICITY; EPITHELIUM CELL; FLOW CYTOMETRY; GEL ELECTROPHORESIS; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; IL 1BETA GENE; IL 6 GENE; IL 8 GENE; IN VITRO STUDY; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MCP 1 GENE; NONHUMAN; PEPTOCLOSTRIDIUM DIFFICILE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEOMICS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY; CACO-2 CELL LINE; CELL CULTURE TECHNIQUE; COLON; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEP-G2 CELL LINE; INTESTINE MUCOSA; METABOLISM; PATHOLOGY; PSEUDOMEMBRANOUS COLITIS; SECRETION (PROCESS);

BACTERIAL PROTEINS; BACTERIAL TOXINS; CACO-2 CELLS; CELL CULTURE TECHNIQUES; CHEMOKINE CCL2; CLOSTRIDIUM DIFFICILE; COLON; CYTOKINES; ENTEROCOLITIS, PSEUDOMEMBRANOUS; ENTEROTOXINS; EPITHELIAL CELLS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HEP G2 CELLS; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; INTESTINAL MUCOSA; MICROSCOPY, ELECTRON, TRANSMISSION; PROTEOMICS;

EID: 85014995659     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2017.03.006     Document Type: Article

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